Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 104114786 . G A CCDS782.1:NM_020978.4:c.223Gaa>Aaa_NP_066188.1:p.75E>K Homo sapiens amylase, alpha 2B (pancreatic) (AMY2B), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3old 1 P04746 98.99 0.0 X-RAY
 2011-04-13 GLU A:60 A:60 0.0 0.0 G -68.2 -20.4 0.0 0.0 0.0 GLC
GLC
ACI
HOH
 4.468
6.878
7.864
2.674
 N
N
N
OE2
 O6
C1
O4
O
3ole 1 P04746 98.99 0.0 X-RAY
 2011-04-13 GLU A:60 A:60 0.0 0.0 G -65.7 -23.8 0.0 0.0 0.0 GLC
G6D
ACI
HOH
 4.426
6.835
7.839
2.703
 N
N
N
OE2
 O6
C1
O4
O
3olg 1 P04746 98.99 0.0 X-RAY
 2011-04-13 GLU A:60 A:60 0.0 0.0 G -66.1 -22.3 0.0 0.0 0.0 GLC
G6D
HSD
HOH
 4.427
6.742
7.754
2.612
 N
N
N
OE2
 O6
C1
O2
O
3oli 1 P04746 98.99 0.0 X-RAY
 2011-04-13 GLU A:60 A:60 0.0 0.0 G -66.3 -22.4 0.0 0.0 0.0 GLC
G6D
HSD
HOH
 4.424
6.752
7.850
2.652
 N
N
N
OE2
 O6
C1
O2
O
6z8l 1 P04746 98.79 0.0 X-RAY
 2020-12-02 GLU A:60 A:60 1.0 0.005 G -62.0 -25.3 1.0 0.005 0.0 GLC
GLC
HOH
 3.774
5.864
2.672
 HA
HA
OE2
 HO6
H1
O
1b2y 1 P04746 98.79 0.0 X-RAY
 2000-02-16 GLU A:60 A:60 0.0 0.0 G -68.5 -21.5 0.0 0.0 0.0 AC1
GLC
G6D
HOH
 7.789
4.474
6.673
3.713
 N
N
N
CG
 O4
O6
C1
O
1bsi 1 P04746 98.59 0.0 X-RAY
 1999-05-18 GLU A:60 A:60 1.0 0.005 G -66.8 -20.9 1.0 0.005 0.0 HOH
 2.832
 OE2
 O
1cpu 1 P04746 98.59 0.0 X-RAY
 1999-06-14 GLU A:60 A:60 0.0 0.0 G -65.7 -21.8 0.0 0.0 0.0 GLC
GLC
HMC
HOH
 4.446
6.859
7.874
2.816
 N
N
N
OE2
 O6
C1
O4
O
1hny 1 P04746 98.59 0.0 X-RAY
 1996-03-08 GLU A:60 A:60 1.0 0.005 G -62.5 -28.5 1.0 0.005 0.0 HOH
 2.576
 OE2
 O
1u2y 1 P04746 98.59 0.0 X-RAY
 2004-09-07 GLU A:60 A:60 0.0 0.0 G -68.3 -21.6 0.0 0.0 0.0 GOX
HOH
 9.475
2.717
 N
OE2
 O7
O
1u30 1 P04746 98.59 0.0 X-RAY
 2004-09-07 GLU A:60 A:60 0.0 0.0 G -66.3 -23.7 0.0 0.0 0.0 LAG
HOH
 4.371
2.666
 N
OE2
 OB6
O
1u33 1 P04746 98.59 0.0 X-RAY
 2004-09-07 GLU A:60 A:60 0.0 0.0 G -63.7 -22.3 0.0 0.0 0.0 LM2
HOH
 4.239
2.741
 N
OE2
 OB6
O
1xcw 1 P04746 98.59 0.0 X-RAY
 2004-12-07 GLU A:60 A:60 0.0 0.0 G -71.2 -21.8 0.0 0.0 0.0 AC1
HOH
 7.540
2.894
 N
OE2
 O4
O
1xcx 1 P04746 98.59 0.0 X-RAY
 2004-12-07 GLU A:60 A:60 0.0 0.0 G -70.6 -20.8 0.0 0.0 0.0 AC1
HOH
 7.406
2.704
 N
OE2
 O4
O
1xd0 1 P04746 98.59 0.0 X-RAY
 2004-12-07 GLU A:60 A:60 1.0 0.005 G -65.2 -22.3 1.0 0.005 0.0 ARE
HOH
 4.420
2.755
 N
OE2
 O6B
O
1xd1 1 P04746 98.59 0.0 X-RAY
 2004-12-07 GLU A:60 A:60 1.0 0.005 G -71.4 -19.0 1.0 0.005 0.0 6SA
HOH
 4.497
2.540
 N
OE2
 OP6
O
2qmk 1 P04746 98.59 0.0 X-RAY
 2008-03-25 GLU A:60 A:60 0.0 0.0 G -68.6 -7.3 0.0 0.0 0.0 HOH
 2.609
 OE2
 O
2qv4 1 P04746 98.59 0.0 X-RAY
 2008-03-25 GLU A:60 A:60 0.0 0.0 G -68.6 -16.8 0.0 0.0 0.0 QV4
HOH
 4.620
2.709
 N
OE2
 O6B
O
3bai 1 P04746 98.59 0.0 X-RAY
 2008-03-25 GLU A:60 A:60 0.0 0.0 G -67.6 -19.1 0.0 0.0 0.0 HOH
 2.638
 OE2
 O
3baj 1 P04746 98.59 0.0 X-RAY
 2008-03-25 GLU A:60 A:60 0.0 0.0 G -68.9 -13.7 0.0 0.0 0.0 ARE
HOH
 4.879
2.489
 N
OE2
 O6B
O
3baw 1 P04746 98.59 0.0 X-RAY
 2008-03-25 GLU A:60 A:60 0.0 0.0 G -70.5 -16.8 0.0 0.0 0.0 HOH
 2.729
 OE2
 O
3ij7 1 P04746 98.59 0.0 X-RAY
 2009-10-27 GLU A:60 A:60 0.0 0.0 G -64.3 -23.5 0.0 0.0 0.0 B9D
BGC
B8D
HOH
 7.624
4.232
6.927
2.742
 N
N
N
OE2
 O2
O6
C1
O
3ij8 1 P04746 98.59 0.0 X-RAY
 2009-10-27 GLU A:60 A:60 0.0 0.0 G -65.6 -23.5 0.0 0.0 0.0 B9D
HOH
 7.594
2.697
 C
OE2
 F1
O
3ij9 1 P04746 98.59 0.0 X-RAY
 2009-10-27 GLU A:60 A:60 0.0 0.0 G -64.5 -23.7 0.0 0.0 0.0 B9D
BGC
HOH
 7.667
4.487
2.756
 N
N
OE2
 O2
O6
O
4gqq 1 P04746 98.59 0.0 X-RAY
 2012-10-24 GLU A:60 A:60 0.0 0.0 G -58.4 -29.5 0.0 0.0 0.0 HOH
 4.749
 O
 O
4gqr 1 P04746 98.59 0.0 X-RAY
 2012-10-24 GLU A:60 A:60 0.0 0.0 G -65.1 -24.2 0.0 0.0 0.0 MYC
HOH
 5.126
2.671
 N
OE2
 O13
O
4w93 1 P04746 98.59 0.0 X-RAY
 2015-07-15 GLU A:60 A:60 0.0 0.0 G -61.7 -24.6 0.0 0.0 0.0 3L9
HOH
 6.851
2.662
 N
OE2
 O6D
O
4x9y 1 P04746 98.59 0.0 X-RAY
 2014-12-31 GLU A:60 A:60 0.0 0.0 G -61.3 -25.3 0.0 0.0 0.0 HOH
 2.685
 OE2
 O
5e0f 1 P04746 98.59 0.0 X-RAY
 2016-09-07 GLU A:60 A:60 1.0 0.005 G -62.3 -26.6 1.0 0.005 0.0 5J7
HOH
 6.590
2.651
 N
OE2
 H571
O
5emy 1 P04746 98.59 0.0 X-RAY
 2016-07-06 GLU A:60 A:60 1.0 0.005 G -61.7 -24.8 1.0 0.005 0.0 5QP
HOH
 3.798
2.652
 HA
OE2
 HO6
O
5kez 1 P04746 98.59 0.0 X-RAY
 2017-03-29 GLU A:60 A:60 0.0 0.0 G -61.3 -25.6 0.0 0.0 0.0 HOH
 2.850
 OE2
 O
5u3a 1 P04746 98.59 0.0 X-RAY
 2017-12-06 GLU A:60 A:60 0.0 0.0 G -62.5 -24.7 0.0 0.0 0.0 HOH
 2.651
 OE2
 O
5va9 1 P04746 98.59 0.0 X-RAY
 2018-03-28 GLU A:60 A:60 0.0 0.0 G -63.0 -24.2 0.0 0.0 0.0 HOH
 2.886
 OE1
 O
GLU B:60 B:60 0.0 0.0 G -62.1 -24.7 NA NA NA
6obx 1 P04746 98.59 0.0 X-RAY
 2020-02-12 GLU A:60 A:60 0.0 0.0 G -61.1 -25.2 0.0 0.0 0.0 ZXU
MPD
HOH
 5.563
7.310
2.681
 HA
HA
OE2
 HD1
HO4
O
6ocn 1 P04746 98.59 0.0 X-RAY
 2020-02-12 GLU A:60 A:60 0.0 0.0 G -62.4 -25.4 0.0 0.0 0.0 ZXY
HOH
 5.671
2.675
 N
OE2
 HD2
O
1xgz 1 P04746 98.39 0.0 X-RAY
 2005-05-24 GLU A:60 A:60 1.0 0.005 G -70.8 -18.7 1.0 0.005 0.0 HOH
 2.731
 OE2
 O
1xh0 1 P04746 98.39 0.0 X-RAY
 2005-05-24 GLU A:60 A:60 0.0 0.0 G -68.5 -20.2 0.0 0.0 0.0 AAO
HOH
 4.445
2.786
 N
OE2
 O6B
O
1xh1 1 P04746 98.39 0.0 X-RAY
 2005-05-24 GLU A:60 A:60 0.0 0.0 G -68.9 -18.6 0.0 0.0 0.0 HOH
 2.663
 OE2
 O
1xh2 1 P04746 98.39 0.0 X-RAY
 2005-05-24 GLU A:60 A:60 0.0 0.0 G -68.5 -17.9 0.0 0.0 0.0 ARE
HOH
 4.567
2.567
 N
OE2
 O6B
O
3bak 1 P04746 98.39 0.0 X-RAY
 2008-03-25 GLU A:60 A:60 0.0 0.0 G -66.5 -19.4 0.0 0.0 0.0 HOH
 2.586
 OE2
 O
3bax 1 P04746 98.39 0.0 X-RAY
 2008-03-25 GLU A:60 A:60 0.0 0.0 G -68.5 -21.0 0.0 0.0 0.0 HOH
 2.668
 OE2
 O
3bay 1 P04746 98.39 0.0 X-RAY
 2008-03-25 GLU A:60 A:60 0.0 0.0 G -71.6 -11.7 0.0 0.0 0.0 ARE
HOH
 4.780
2.807
 N
OE2
 O6B
O
1kgw 1 P04746 98.39 0.0 X-RAY
 2002-01-16 GLU A:60 A:60 0.0 0.0 G -69.8 -22.5 0.0 0.0 0.0 HOH
 2.647
 OE2
 O
2cpu 1 P04746 98.39 0.0 X-RAY
 2001-06-30 GLU A:60 A:60 0.0 0.0 G -65.7 -19.3 0.0 0.0 0.0 HOH
 3.704
 CG
 O
3cpu 1 P04746 98.39 0.0 X-RAY
 2001-06-30 GLU A:60 A:60 0.0 0.0 G -72.3 -21.9 0.0 0.0 0.0 GLC
GLC
HOH
 4.740
6.923
3.849
 N
N
CG
 O6
C1
O
5td4 1 P04746 98.39 0.0 X-RAY
 2016-11-02 GLU A:60 A:60 0.0 0.0 G -62.9 -26.5 0.0 0.0 0.0 GLC
GLC
GLC
HOH
 8.154
4.408
6.728
2.571
 N
N
N
OE2
 O4
O6
C1
O
1kgx 1 P04746 98.39 0.0 X-RAY
 2002-01-16 GLU A:60 A:60 0.0 0.0 G -66.7 -21.9 0.0 0.0 0.0 HOH
 2.698
 OE2
 O
1kbb 1 P04746 98.39 0.0 X-RAY
 2002-04-10 GLU A:60 A:60 0.0 0.0 G -69.0 -25.3 0.0 0.0 0.0 HOH
 2.614
 OE2
 O
1kgu 1 P04746 98.39 0.0 X-RAY
 2002-01-16 GLU A:60 A:60 0.0 0.0 G -69.2 -22.1 0.0 0.0 0.0 HOH
 2.695
 OE2
 O
1kb3 1 P04746 98.39 0.0 X-RAY
 2002-05-01 GLU A:60 A:60 0.0 0.0 G -66.9 -21.5 0.0 0.0 0.0 HOH
 2.755
 OE2
 O
1kbk 1 P04746 98.39 0.0 X-RAY
 2002-04-10 GLU A:60 A:60 0.0 0.0 G -66.5 -22.7 0.0 0.0 0.0 HOH
 2.706
 OE2
 O
1c8q 1 P04745 97.58 0.0 X-RAY
 2001-06-13 GLU A:60 A:60 0.0 0.0 G -69.5 -24.7 0.0 0.0 0.0 HOH
 2.675
 OE2
 O
1mfv 1 P04745 97.58 0.0 X-RAY
 2002-11-20 GLU A:60 A:60 1.0 0.005 G -61.1 -25.8 1.0 0.005 0.0 GLC
AGL
HMC
HOH
 4.408
6.922
7.794
2.609
 N
N
N
OE2
 O6
C1
O4
O
1smd 1 P04745 97.58 0.0 X-RAY
 1996-07-11 GLU A:60 A:60 1.0 0.005 G -71.8 -21.5 1.0 0.005 0.0 HOH
 3.814
 CG
 O
1xv8 1 P04745 97.58 0.0 X-RAY
 2005-10-11 GLU A:60 A:60 0.0 0.0 G -73.3 -14.9 0.0 0.0 0.0 HOH
 3.547
 CG
 O
GLU B:60 B:60 0.0 0.0 G -73.3 -14.9 0.0 0.0 0.0 HOH
 3.547
 CG
 O
1q4n 1 P04745 97.38 0.0 X-RAY
 2004-03-16 GLU A:60 X:60 0.0 0.0 G -60.5 -27.6 0.0 0.0 0.0 TAM
HOH
 8.273
2.599
 O
OE2
 O6
O
1z32 1 P04745 97.38 0.0 X-RAY
 2005-05-31 GLU A:60 X:60 1.0 0.005 G -61.1 -26.0 1.0 0.005 0.0 GLC
HMC
HOH
 4.630
7.611
2.704
 N
N
OE2
 O6
O4
O
1jxj 1 P04745 97.38 0.0 X-RAY
 2001-09-14 GLU A:60 A:60 0.0 0.0 G -68.6 -22.8 0.0 0.0 0.0 HOH
 2.691
 OE2
 O
1nm9 1 P04745 97.38 0.0 X-RAY
 2004-01-20 GLU A:60 A:60 0.0 0.0 G -64.2 -27.9 0.0 0.0 0.0 HMC
HOH
 7.479
2.659
 N
OE2
 O4
O
3blk 1 P04745 97.38 0.0 X-RAY
 2008-11-25 GLU A:60 A:60 0.0 0.0 G -61.3 -25.5 0.0 0.0 0.0 GLC
AGL
HMC
HOH
 4.575
7.000
7.935
2.630
 N
N
N
OE2
 O6
C1
O4
O
3blp 1 P04745 97.38 0.0 X-RAY
 2008-11-18 GLU A:60 X:60 0.0 0.0 G -61.8 -26.5 0.0 0.0 0.0 GLC
AGL
HMC
HOH
 4.505
6.948
7.853
2.621
 N
N
N
OE2
 O6
C1
O4
O
1jxk 1 P04745 96.57 0.0 X-RAY
 2001-09-14 GLU A:60 A:60 1.0 0.005 G -64.0 -21.5 1.0 0.005 0.0 HOH
 2.586
 OE2
 O
1mfu 1 P04745 96.57 0.0 X-RAY
 2002-11-20 GLU A:60 A:60 1.0 0.005 G -60.3 -31.2 1.0 0.005 0.0 GLC
AGL
HMC
HOH
 4.367
6.800
7.771
2.612
 N
N
N
OE2
 O6
C1
O4
O
3dhp 1 P04745 96.37 0.0 X-RAY
 2008-07-01 GLU A:60 A:60 0.0 0.0 G -60.6 -26.7 0.0 0.0 0.0 GLC
HMC
HOH
 4.685
7.437
2.662
 N
N
OE2
 O6
O4
O
1kxq 1 P00690 87.1 0.0 X-RAY
 2002-06-19 GLU A:60 A:60 0.0 0.0 G -67.4 -22.5 0.0 0.0 0.0 HOH
 3.750
 CG
 O
GLU B:60 B:60 0.0 0.0 G -67.4 -21.0 NA NA NA
GLU C:60 C:60 0.0 0.0 G -65.0 -22.0 NA NA NA
GLU D:60 D:60 0.0 0.0 G -66.3 -22.3 NA NA NA
1kxt 1 P00690 87.1 0.0 X-RAY
 2002-06-19 GLU A:60 A:60 0.0 0.0 G -63.6 -23.5 0.0 0.0 0.0 HOH
 2.625
 CB
 O
GLU C:60 C:60 0.0 0.0 G -75.9 -22.8 NA NA NA
GLU E:60 E:60 0.0 0.0 G -59.5 -24.6 NA NA NA
1kxv 1 P00690 87.1 0.0 X-RAY
 2002-06-19 GLU A:60 A:60 0.0 0.0 G -65.3 -21.1 0.0 0.0 0.0 HOH
 2.591
 OE1
 O
GLU B:60 B:60 0.0 0.0 G -67.3 -21.9 NA NA NA
1dhk 1 P00690 87.1 0.0 X-RAY
 1997-12-24 GLU A:60 A:60 0.0 0.0 G -66.2 -25.6 0.0 0.0 0.0 HOH
 2.032
 OE2
 H1
1ppi 1 P00690 87.1 0.0 X-RAY
 1995-05-24 GLU A:60 A:60 0.0 0.0 G -64.3 -22.2 0.0 0.0 0.0 GLC
GLC
DAF
HOH
 4.544
6.661
7.986
2.776
 N
N
N
OE2
 O6
C1
O4H
O
3l2l 1 P00690 86.9 0.0 X-RAY
 2010-04-14 GLU A:60 A:60 0.0 0.0 G -64.7 -23.5 0.0 0.0 0.0 GLC
GLC
GLC
GLC
GLC
HOH
 9.953
7.811
3.856
5.654
5.550
2.560
 OE1
N
HA
HA
HA
OE2
 HO3
H61
HO6
H1
H1
O
3l2m 1 P00690 86.9 0.0 X-RAY
 2010-04-14 GLU A:60 A:60 0.0 0.0 G -62.1 -23.7 0.0 0.0 0.0 GLC
GLC
GLC
GLC
GLC
GLC
HOH
 8.481
8.890
9.776
5.937
9.512
6.134
2.735
 HA
HA
OE1
N
HA
N
OE2
 HO3
HO2
HO3
H1
H1
H62
O
1ua3 1 P00690 86.9 0.0 X-RAY
 2003-10-14 GLU A:60 A:60 0.0 0.0 G -60.7 -25.2 0.0 0.0 0.0 GLC
GLC
GLC
HOH
 7.766
4.398
6.762
2.637
 N
N
N
OE1
 O4
O6
C1
O
1vah 1 P00690 86.9 0.0 X-RAY
 2005-04-26 GLU A:60 A:60 0.0 0.0 G -71.3 -19.8 0.0 0.0 0.0 NPO
HOH
 5.776
2.736
 N
OE1
 C5
O
1jfh 1 P00690 86.9 0.0 X-RAY
 1998-12-02 GLU A:60 A:60 0.0 0.0 G -67.7 -21.5 0.0 0.0 0.0 MA3
MA2
HG
HOH
 4.505
7.138
9.199
2.697
 N
N
O
OE2
 O6
C1
HG
O
1ose 1 P00690 86.69 0.0 X-RAY
 1997-04-01 GLU A:60 A:60 0.0 0.0 G -65.4 -20.9 0.0 0.0 0.0 AC1
GLC
AC1
HOH
 7.893
4.237
6.761
2.741
 N
N
N
OE2
 O4
O6
C1
O
1hx0 1 P00690 86.69 0.0 X-RAY
 2001-08-08 GLU A:60 A:60 0.0 0.0 G -61.1 -24.2 0.0 0.0 0.0 AC1
GLC
AC1
EDO
HOH
 7.971
4.441
6.705
8.373
2.680
 N
N
N
OE2
OE1
 O4
O6
C1
O2
O
1wo2 1 P00690 86.69 0.0 X-RAY
 2005-03-15 GLU A:60 A:60 0.0 0.0 G -67.2 -22.8 0.0 0.0 0.0 BGC
GLC
GLC
EDO
EDO
HOH
 7.844
4.482
6.854
6.704
5.168
2.687
 N
N
N
CA
OE1
OE1
 O4
O6
C1
O1
O1
O
1bvn 1 P00690 86.69 0.0 X-RAY
 1998-09-23 GLU A:60 P:60 0.0 0.0 G -85.2 -13.5 0.0 0.0 0.0 HOH
 2.785
 OE2
 O
1pif 1 P00690 86.49 0.0 X-RAY
 1996-12-07 GLU A:60 A:60 0.0 0.0 G -66.0 -26.4 0.0 0.0 0.0 HOH
 2.648
 OE2
 O
1pig 1 P00690 86.49 0.0 X-RAY
 1996-12-07 GLU A:60 A:60 0.0 0.0 G -64.8 -23.5 0.0 0.0 0.0 GLC
AGL
HMC
HOH
 4.504
6.763
7.962
3.307
 N
N
N
CG
 O6
C1
O4
O
4x0n 1 P00690 86.49 0.0 X-RAY
 2015-11-25 GLU A:60 A:60 0.0 0.0 G -62.7 -25.9 0.0 0.0 0.0 GOL
HOH
 9.494
2.482
 N
OE2
 O3
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p19961-f1 1 P19961 100.0 0.0 GLU A:75 A:75 0.0 0.0 G -59.1 -27.1
af-p04746-f1 1 P04746 98.83 0.0 GLU A:75 A:75 0.0 0.0 G -59.8 -26.4
af-p0dte7-f1 1 P0DTE7 97.46 0.0 GLU A:75 A:75 0.0 0.0 G -59.6 -27.3
af-p0dte8-f1 1 P0DTE8 97.46 0.0 GLU A:75 A:75 0.0 0.0 G -59.7 -27.4
af-p0dub6-f1 1 P0DUB6 97.46 0.0 GLU A:75 A:75 0.0 0.0 G -60.0 -26.6