Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 104114873 . G A CCDS782.1:NM_020978.4:c.310Gtt>Att_NP_066188.1:p.104V>I Homo sapiens amylase, alpha 2B (pancreatic) (AMY2B), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3old 1 P04746 98.99 0.0 X-RAY
 2011-04-13 VAL A:89 A:89 48.0 0.31 T -109.9 19.5 48.0 0.31 0.0 HOH
 2.660
 O
 O
3ole 1 P04746 98.99 0.0 X-RAY
 2011-04-13 VAL A:89 A:89 50.0 0.323 T -113.2 16.5 50.0 0.323 0.0 HOH
 2.691
 O
 O
3olg 1 P04746 98.99 0.0 X-RAY
 2011-04-13 VAL A:89 A:89 49.0 0.316 T -109.1 15.3 49.0 0.316 0.0 HOH
 2.885
 O
 O
3oli 1 P04746 98.99 0.0 X-RAY
 2011-04-13 VAL A:89 A:89 48.0 0.31 T -112.0 16.5 48.0 0.31 0.0 MPD
HOH
 7.497
2.902
 N
O
 O2
O
6z8l 1 P04746 98.79 0.0 X-RAY
 2020-12-02 VAL A:89 A:89 51.0 0.329 T -108.7 13.8 51.0 0.329 0.0 HOH
 2.784
 O
 O
1b2y 1 P04746 98.79 0.0 X-RAY
 2000-02-16 VAL A:89 A:89 55.0 0.355 T -111.8 12.5 55.0 0.355 0.0 HOH
 3.128
 CG2
 O
1bsi 1 P04746 98.59 0.0 X-RAY
 1999-05-18 VAL A:89 A:89 47.0 0.303 T -117.0 11.4 47.0 0.303 0.0 HOH
 2.998
 O
 O
1cpu 1 P04746 98.59 0.0 X-RAY
 1999-06-14 VAL A:89 A:89 48.0 0.31 T -112.8 15.2 48.0 0.31 0.0 HOH
 3.018
 O
 O
1hny 1 P04746 98.59 0.0 X-RAY
 1996-03-08 VAL A:89 A:89 58.0 0.374 T -110.1 10.7 58.0 0.374 0.0 HOH
 3.301
 CG2
 O
1u2y 1 P04746 98.59 0.0 X-RAY
 2004-09-07 VAL A:89 A:89 45.0 0.29 T -111.4 9.7 45.0 0.29 0.0 HOH
 3.009
 O
 O
1u30 1 P04746 98.59 0.0 X-RAY
 2004-09-07 VAL A:89 A:89 50.0 0.323 T -110.9 10.6 50.0 0.323 0.0 HOH
 4.183
 CB
 O
1u33 1 P04746 98.59 0.0 X-RAY
 2004-09-07 VAL A:89 A:89 44.0 0.284 T -104.4 12.8 44.0 0.284 0.0 HOH
 2.844
 O
 O
1xcw 1 P04746 98.59 0.0 X-RAY
 2004-12-07 VAL A:89 A:89 46.0 0.297 T -113.1 11.2 46.0 0.297 0.0 HOH
 4.604
 CB
 O
1xcx 1 P04746 98.59 0.0 X-RAY
 2004-12-07 VAL A:89 A:89 42.0 0.271 T -110.0 6.6 42.0 0.271 0.0 HOH
 2.909
 O
 O
1xd0 1 P04746 98.59 0.0 X-RAY
 2004-12-07 VAL A:89 A:89 45.0 0.29 T -110.0 11.4 45.0 0.29 0.0 HOH
 3.450
 CG1
 O
1xd1 1 P04746 98.59 0.0 X-RAY
 2004-12-07 VAL A:89 A:89 47.0 0.303 T -122.2 2.1 47.0 0.303 0.0 HOH
 9.236
 N
 O
2qmk 1 P04746 98.59 0.0 X-RAY
 2008-03-25 VAL A:89 A:89 55.0 0.355 T -117.8 19.2 55.0 0.355 0.0 HOH
 2.969
 O
 O
2qv4 1 P04746 98.59 0.0 X-RAY
 2008-03-25 VAL A:89 A:89 50.0 0.323 T -109.2 15.8 50.0 0.323 0.0 HOH
 2.915
 O
 O
3bai 1 P04746 98.59 0.0 X-RAY
 2008-03-25 VAL A:89 A:89 46.0 0.297 T -109.0 13.5 46.0 0.297 0.0 HOH
 2.868
 O
 O
3baj 1 P04746 98.59 0.0 X-RAY
 2008-03-25 VAL A:89 A:89 44.0 0.284 T -113.1 18.2 44.0 0.284 0.0 HOH
 3.665
 CG1
 O
3baw 1 P04746 98.59 0.0 X-RAY
 2008-03-25 VAL A:89 A:89 48.0 0.31 T -109.5 13.4 48.0 0.31 0.0 HOH
 2.790
 O
 O
3ij7 1 P04746 98.59 0.0 X-RAY
 2009-10-27 VAL A:89 A:89 44.0 0.284 T -110.0 7.8 44.0 0.284 0.0 HOH
 2.687
 O
 O
3ij8 1 P04746 98.59 0.0 X-RAY
 2009-10-27 VAL A:89 A:89 47.0 0.303 T -111.1 15.5 47.0 0.303 0.0 HOH
 2.884
 O
 O
3ij9 1 P04746 98.59 0.0 X-RAY
 2009-10-27 VAL A:89 A:89 43.0 0.277 T -106.0 8.9 43.0 0.277 0.0 HOH
 2.671
 O
 O
4gqq 1 P04746 98.59 0.0 X-RAY
 2012-10-24 VAL A:89 A:89 49.0 0.316 T -108.0 19.7 49.0 0.316 0.0 HOH
 3.788
 CG1
 O
4gqr 1 P04746 98.59 0.0 X-RAY
 2012-10-24 VAL A:89 A:89 54.0 0.348 T -109.4 17.7 54.0 0.348 0.0 HOH
 2.691
 O
 O
4w93 1 P04746 98.59 0.0 X-RAY
 2015-07-15 VAL A:89 A:89 49.0 0.316 T -101.4 10.2 49.0 0.316 0.0 HOH
 2.928
 O
 O
4x9y 1 P04746 98.59 0.0 X-RAY
 2014-12-31 VAL A:89 A:89 51.0 0.329 T -109.5 14.6 51.0 0.329 0.0 HOH
 2.752
 O
 O
5e0f 1 P04746 98.59 0.0 X-RAY
 2016-09-07 VAL A:89 A:89 53.0 0.342 T -110.9 17.1 53.0 0.342 0.0 HOH
 2.770
 O
 O
5emy 1 P04746 98.59 0.0 X-RAY
 2016-07-06 VAL A:89 A:89 52.0 0.335 T -105.3 14.3 52.0 0.335 0.0 HOH
 2.830
 O
 O
5kez 1 P04746 98.59 0.0 X-RAY
 2017-03-29 VAL A:89 A:89 52.0 0.335 T -112.9 14.5 52.0 0.335 0.0 HOH
 3.381
 CG1
 O
5u3a 1 P04746 98.59 0.0 X-RAY
 2017-12-06 VAL A:89 A:89 51.0 0.329 T -108.6 15.2 51.0 0.329 0.0 HOH
 2.745
 O
 O
5va9 1 P04746 98.59 0.0 X-RAY
 2018-03-28 VAL A:89 A:89 50.0 0.323 T -102.8 9.9 50.0 0.323 0.0 HOH
 5.663
 N
 O
VAL B:89 B:89 49.0 0.316 T -102.2 8.8 NA NA NA
6obx 1 P04746 98.59 0.0 X-RAY
 2020-02-12 VAL A:89 A:89 52.0 0.335 T -106.3 13.0 52.0 0.335 0.0 HOH
 2.758
 O
 O
6ocn 1 P04746 98.59 0.0 X-RAY
 2020-02-12 VAL A:89 A:89 52.0 0.335 T -107.4 13.3 52.0 0.335 0.0 HOH
 2.755
 O
 O
1xgz 1 P04746 98.39 0.0 X-RAY
 2005-05-24 VAL A:89 A:89 46.0 0.297 T -109.7 9.7 46.0 0.297 0.0 HOH
 2.893
 O
 O
1xh0 1 P04746 98.39 0.0 X-RAY
 2005-05-24 VAL A:89 A:89 47.0 0.303 T -110.4 8.1 47.0 0.303 0.0 HOH
 3.274
 CG2
 O
1xh1 1 P04746 98.39 0.0 X-RAY
 2005-05-24 VAL A:89 A:89 44.0 0.284 T -109.7 4.9 44.0 0.284 0.0 HOH
 2.895
 O
 O
1xh2 1 P04746 98.39 0.0 X-RAY
 2005-05-24 VAL A:89 A:89 49.0 0.316 T -115.4 10.3 49.0 0.316 0.0 HOH
 2.780
 O
 O
3bak 1 P04746 98.39 0.0 X-RAY
 2008-03-25 VAL A:89 A:89 46.0 0.297 T -112.4 14.4 46.0 0.297 0.0 HOH
 2.979
 O
 O
3bax 1 P04746 98.39 0.0 X-RAY
 2008-03-25 VAL A:89 A:89 50.0 0.323 T -113.1 18.7 50.0 0.323 0.0 HOH
 2.799
 O
 O
3bay 1 P04746 98.39 0.0 X-RAY
 2008-03-25 VAL A:89 A:89 44.0 0.284 T -107.3 16.0 44.0 0.284 0.0 HOH
 3.155
 O
 O
1kgw 1 P04746 98.39 0.0 X-RAY
 2002-01-16 VAL A:89 A:89 46.0 0.297 T -108.3 -1.5 46.0 0.297 0.0 HOH
 4.308
 CB
 O
2cpu 1 P04746 98.39 0.0 X-RAY
 2001-06-30 VAL A:89 A:89 49.0 0.316 T -118.5 6.3 49.0 0.316 0.0 HOH
 3.463
 CG2
 O
3cpu 1 P04746 98.39 0.0 X-RAY
 2001-06-30 VAL A:89 A:89 51.0 0.329 T -108.9 7.5 51.0 0.329 0.0 HOH
 3.731
 CG2
 O
5td4 1 P04746 98.39 0.0 X-RAY
 2016-11-02 VAL A:89 A:89 51.0 0.329 T -104.3 15.3 51.0 0.329 0.0 HOH
 3.157
 O
 O
1kgx 1 P04746 98.39 0.0 X-RAY
 2002-01-16 VAL A:89 A:89 46.0 0.297 T -113.1 8.2 46.0 0.297 0.0 HOH
 2.901
 O
 O
1kbb 1 P04746 98.39 0.0 X-RAY
 2002-04-10 VAL A:89 A:89 47.0 0.303 T -107.2 6.9 47.0 0.303 0.0 HOH
 3.162
 CG2
 O
1kgu 1 P04746 98.39 0.0 X-RAY
 2002-01-16 VAL A:89 A:89 47.0 0.303 T -106.4 8.1 47.0 0.303 0.0 HOH
 3.621
 CG1
 O
1kb3 1 P04746 98.39 0.0 X-RAY
 2002-05-01 VAL A:89 A:89 47.0 0.303 T -115.7 12.3 47.0 0.303 0.0 HOH
 2.762
 CB
 O
1kbk 1 P04746 98.39 0.0 X-RAY
 2002-04-10 VAL A:89 A:89 46.0 0.297 T -109.1 9.2 46.0 0.297 0.0 HOH
 2.754
 O
 O
1c8q 1 P04745 97.58 0.0 X-RAY
 2001-06-13 VAL A:89 A:89 48.0 0.31 T -116.4 25.0 48.0 0.31 0.0 HOH
 2.780
 O
 O
1mfv 1 P04745 97.58 0.0 X-RAY
 2002-11-20 VAL A:89 A:89 49.0 0.316 T -107.5 12.2 49.0 0.316 0.0 HOH
 2.912
 O
 O
1smd 1 P04745 97.58 0.0 X-RAY
 1996-07-11 VAL A:89 A:89 53.0 0.342 T -106.1 14.2 53.0 0.342 0.0 HOH
 3.514
 CG1
 O
1xv8 1 P04745 97.58 0.0 X-RAY
 2005-10-11 VAL A:89 A:89 43.0 0.277 T -113.7 12.3 43.0 0.277 0.0 HOH
 7.791
 C
 O
VAL B:89 B:89 45.0 0.29 T -113.7 12.3 45.0 0.29 0.0 HOH
 7.791
 C
 O
1q4n 1 P04745 97.38 0.0 X-RAY
 2004-03-16 VAL A:89 X:89 49.0 0.316 T -105.6 20.7 49.0 0.316 0.0 HOH
 2.951
 O
 O
1z32 1 P04745 97.38 0.0 X-RAY
 2005-05-31 VAL A:89 X:89 51.0 0.329 T -107.6 11.5 51.0 0.329 0.0 HOH
 2.707
 O
 O
1jxj 1 P04745 97.38 0.0 X-RAY
 2001-09-14 VAL A:89 A:89 52.0 0.335 T -110.4 15.4 52.0 0.335 0.0 HOH
 3.520
 CG1
 O
1nm9 1 P04745 97.38 0.0 X-RAY
 2004-01-20 VAL A:89 A:89 50.0 0.323 T -105.1 16.2 50.0 0.323 0.0 HOH
 2.737
 O
 O
3blk 1 P04745 97.38 0.0 X-RAY
 2008-11-25 VAL A:89 A:89 52.0 0.335 T -107.7 12.4 52.0 0.335 0.0 HOH
 3.738
 CG1
 O
3blp 1 P04745 97.38 0.0 X-RAY
 2008-11-18 VAL A:89 X:89 50.0 0.323 T -107.7 9.3 50.0 0.323 0.0 HOH
 2.899
 O
 O
1jxk 1 P04745 96.57 0.0 X-RAY
 2001-09-14 VAL A:89 A:89 48.0 0.31 T -111.9 14.8 48.0 0.31 0.0 HOH
 3.578
 CG1
 O
1mfu 1 P04745 96.57 0.0 X-RAY
 2002-11-20 VAL A:89 A:89 50.0 0.323 T -109.6 18.8 50.0 0.323 0.0 HOH
 2.933
 O
 O
3dhp 1 P04745 96.37 0.0 X-RAY
 2008-07-01 VAL A:89 A:89 53.0 0.342 T -109.6 14.3 53.0 0.342 0.0 HOH
 2.839
 O
 O
1kxq 1 P00690 87.1 0.0 X-RAY
 2002-06-19 VAL A:89 A:89 53.0 0.342 T -108.8 19.5 53.0 0.342 0.0 HOH
 2.734
 O
 O
VAL B:89 B:89 52.0 0.335 T -113.5 17.5 NA NA NA
VAL C:89 C:89 52.0 0.335 T -109.6 20.3 NA NA NA
VAL D:89 D:89 48.0 0.31 T -108.1 15.6 NA NA NA
1kxt 1 P00690 87.1 0.0 X-RAY
 2002-06-19 VAL A:89 A:89 52.0 0.335 T -109.6 20.3 52.0 0.335 0.0 HOH
 2.421
 CG1
 O
VAL C:89 C:89 50.0 0.323 T -119.1 11.7 NA NA NA
VAL E:89 E:89 54.0 0.348 T -116.5 21.1 NA NA NA
1kxv 1 P00690 87.1 0.0 X-RAY
 2002-06-19 VAL A:89 A:89 52.0 0.335 T -114.2 19.5 52.0 0.335 0.0 HOH
 2.662
 O
 O
VAL B:89 B:89 54.0 0.348 T -109.8 17.7 NA NA NA
1dhk 1 P00690 87.1 0.0 X-RAY
 1997-12-24 VAL A:89 A:89 50.0 0.323 T -104.0 17.8 50.0 0.323 0.0 HOH
 3.464
 H
 H2
1ppi 1 P00690 87.1 0.0 X-RAY
 1995-05-24 VAL A:89 A:89 52.0 0.335 T -102.4 14.2 52.0 0.335 0.0 HOH
 2.827
 O
 O
3l2l 1 P00690 86.9 0.0 X-RAY
 2010-04-14 VAL A:89 A:89 53.0 0.342 T -104.5 18.4 53.0 0.342 0.0 HOH
 2.662
 HG12
 O
3l2m 1 P00690 86.9 0.0 X-RAY
 2010-04-14 VAL A:89 A:89 55.0 0.355 T -108.1 17.3 55.0 0.355 0.0 HOH
 2.748
 O
 O
1ua3 1 P00690 86.9 0.0 X-RAY
 2003-10-14 VAL A:89 A:89 53.0 0.342 T -110.5 19.6 53.0 0.342 0.0 HOH
 2.679
 O
 O
1vah 1 P00690 86.9 0.0 X-RAY
 2005-04-26 VAL A:89 A:89 45.0 0.29 T -106.2 11.9 45.0 0.29 0.0 HOH
 4.983
 N
 O
1jfh 1 P00690 86.9 0.0 X-RAY
 1998-12-02 VAL A:89 A:89 50.0 0.323 T -110.5 15.2 50.0 0.323 0.0 HOH
 2.779
 O
 O
1ose 1 P00690 86.69 0.0 X-RAY
 1997-04-01 VAL A:89 A:89 50.0 0.323 T -106.5 15.0 50.0 0.323 0.0 HOH
 3.525
 CG1
 O
1hx0 1 P00690 86.69 0.0 X-RAY
 2001-08-08 VAL A:89 A:89 54.0 0.348 T -111.8 19.9 54.0 0.348 0.0 HOH
 2.699
 O
 O
1wo2 1 P00690 86.69 0.0 X-RAY
 2005-03-15 VAL A:89 A:89 52.0 0.335 T -109.6 17.6 52.0 0.335 0.0 HOH
 2.639
 O
 O
1bvn 1 P00690 86.69 0.0 X-RAY
 1998-09-23 VAL A:89 P:89 43.0 0.277 T -104.3 13.1 43.0 0.277 0.0 HOH
 4.389
 CG1
 O
1pif 1 P00690 86.49 0.0 X-RAY
 1996-12-07 VAL A:89 A:89 48.0 0.31 T -112.1 13.6 48.0 0.31 0.0 HOH
 3.517
 CG1
 O
1pig 1 P00690 86.49 0.0 X-RAY
 1996-12-07 VAL A:89 A:89 49.0 0.316 T -99.4 15.3 49.0 0.316 0.0 HOH
 2.876
 O
 O
4x0n 1 P00690 86.49 0.0 X-RAY
 2015-11-25 VAL A:89 A:89 47.0 0.303 T -112.1 19.7 47.0 0.303 0.0 HOH
 3.575
 CG1
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p19961-f1 1 P19961 100.0 0.0 VAL A:104 A:104 48.0 0.31 T -98.0 9.8
af-p04746-f1 1 P04746 98.83 0.0 VAL A:104 A:104 44.0 0.284 T -99.8 11.5
af-p0dte7-f1 1 P0DTE7 97.46 0.0 VAL A:104 A:104 48.0 0.31 T -98.3 10.2
af-p0dte8-f1 1 P0DTE8 97.46 0.0 VAL A:104 A:104 46.0 0.297 T -98.1 10.0
af-p0dub6-f1 1 P0DUB6 97.46 0.0 VAL A:104 A:104 45.0 0.29 T -99.5 10.8