Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 104115722 . C A CCDS782.1:NM_020978.4:c.353tCt>tAt_NP_066188.1:p.118S>Y Homo sapiens amylase, alpha 2B (pancreatic) (AMY2B), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3old 1 P04746 98.99 0.0 X-RAY
 2011-04-13 CYS A:103 A:103 0.0 0.0 E -83.6 174.8 0.0 0.0 0.0 GLC
GLC
ACI
HOH
 7.258
5.544
8.899
5.958
 C
C
CA
C
 C6
C6
O6
O
3ole 1 P04746 98.99 0.0 X-RAY
 2011-04-13 CYS A:103 A:103 0.0 0.0 E -82.4 173.2 0.0 0.0 0.0 GLC
G6D
ACI
ACI
HOH
 7.262
5.651
8.411
8.865
5.868
 C
C
C
CA
C
 C6
C6
N1
O6
O
3olg 1 P04746 98.99 0.0 X-RAY
 2011-04-13 CYS A:103 A:103 0.0 0.0 E -89.1 -179.8 0.0 0.0 0.0 GLC
G6D
HSD
HSD
HOH
 7.185
6.158
8.790
8.790
7.116
 C
C
C
CA
N
 C6
C6
O2
O1
O
3oli 1 P04746 98.99 0.0 X-RAY
 2011-04-13 CYS A:103 A:103 0.0 0.0 E -89.4 175.6 0.0 0.0 0.0 GLC
G6D
HSD
HSD
HOH
 7.273
5.908
8.703
8.908
5.767
 C
C
C
CA
C
 C6
C6
N1
O1
O
6z8l 1 P04746 98.79 0.0 X-RAY
 2020-12-02 CYS A:103 A:103 0.0 0.0 E -94.0 -179.3 0.0 0.0 0.0 GLC
GLC
HOH
 5.840
4.967
5.707
 HA
C
C
 H61
H61
O
1b2y 1 P04746 98.79 0.0 X-RAY
 2000-02-16 CYS A:103 A:103 0.0 0.0 E -81.2 -177.6 0.0 0.0 0.0 AC1
GLC
G6D
HOH
 8.860
7.406
5.779
7.050
 CA
CA
C
N
 O6B
C6
C6
O
1bsi 1 P04746 98.59 0.0 X-RAY
 1999-05-18 CYS A:103 A:103 0.0 0.0 E -85.5 178.2 0.0 0.0 0.0 HOH
 5.855
 C
 O
1cpu 1 P04746 98.59 0.0 X-RAY
 1999-06-14 CYS A:103 A:103 0.0 0.0 E -81.7 177.7 0.0 0.0 0.0 GLC
GLC
HMC
HOH
 7.153
5.545
8.706
5.954
 CA
C
CA
C
 C6
O6
O7
O
1hny 1 P04746 98.59 0.0 X-RAY
 1996-03-08 CYS A:103 A:103 0.0 0.0 E -86.3 -174.6 0.0 0.0 0.0 HOH
 3.001
 O
 O
1u2y 1 P04746 98.59 0.0 X-RAY
 2004-09-07 CYS A:103 A:103 0.0 0.0 E -81.9 178.4 0.0 0.0 0.0 HOH
 5.667
 C
 O
1u30 1 P04746 98.59 0.0 X-RAY
 2004-09-07 CYS A:103 A:103 0.0 0.0 E -80.4 179.4 0.0 0.0 0.0 LAG
HOH
 5.734
5.961
 C
C
 OD6
O
1u33 1 P04746 98.59 0.0 X-RAY
 2004-09-07 CYS A:103 A:103 0.0 0.0 E -87.0 176.9 0.0 0.0 0.0 LM2
HOH
 5.527
5.635
 C
C
 OD6
O
1xcw 1 P04746 98.59 0.0 X-RAY
 2004-12-07 CYS A:103 A:103 0.0 0.0 E -88.1 177.7 0.0 0.0 0.0 AC1
HOH
 8.786
5.989
 CA
C
 O6B
O
1xcx 1 P04746 98.59 0.0 X-RAY
 2004-12-07 CYS A:103 A:103 0.0 0.0 E -74.6 178.2 0.0 0.0 0.0 AC1
HOH
 8.777
6.036
 CA
C
 O6B
O
1xd0 1 P04746 98.59 0.0 X-RAY
 2004-12-07 CYS A:103 A:103 0.0 0.0 E -80.4 178.1 0.0 0.0 0.0 ARE
HOH
 5.854
6.031
 C
C
 C6A
O
1xd1 1 P04746 98.59 0.0 X-RAY
 2004-12-07 CYS A:103 A:103 0.0 0.0 E -75.7 -178.3 0.0 0.0 0.0 6SA
HOH
 5.530
7.148
 C
N
 OV6
O
2qmk 1 P04746 98.59 0.0 X-RAY
 2008-03-25 CYS A:103 A:103 0.0 0.0 E -91.6 177.7 0.0 0.0 0.0 HOH
 5.698
 C
 O
2qv4 1 P04746 98.59 0.0 X-RAY
 2008-03-25 CYS A:103 A:103 0.0 0.0 E -81.1 178.4 0.0 0.0 0.0 QV4
HOH
 5.147
6.938
 C
CB
 O4Q
O
3bai 1 P04746 98.59 0.0 X-RAY
 2008-03-25 CYS A:103 A:103 0.0 0.0 E -84.4 179.2 0.0 0.0 0.0 HOH
 5.957
 C
 O
3baj 1 P04746 98.59 0.0 X-RAY
 2008-03-25 CYS A:103 A:103 0.0 0.0 E -81.8 -176.8 0.0 0.0 0.0 ARE
HOH
 5.895
6.148
 C
C
 C6A
O
3baw 1 P04746 98.59 0.0 X-RAY
 2008-03-25 CYS A:103 A:103 0.0 0.0 E -79.9 178.2 0.0 0.0 0.0 HOH
 5.812
 C
 O
3ij7 1 P04746 98.59 0.0 X-RAY
 2009-10-27 CYS A:103 A:103 0.0 0.0 E -87.6 179.9 0.0 0.0 0.0 B9D
BGC
B8D
HOH
 8.214
6.996
5.630
5.807
 CA
CA
C
C
 F1
C6
C6
O
3ij8 1 P04746 98.59 0.0 X-RAY
 2009-10-27 CYS A:103 A:103 0.0 0.0 E -80.2 177.4 0.0 0.0 0.0 B9D
HOH
 8.296
5.831
 CA
C
 F1
O
3ij9 1 P04746 98.59 0.0 X-RAY
 2009-10-27 CYS A:103 A:103 0.0 0.0 E -85.3 177.4 0.0 0.0 0.0 B9D
BGC
HOH
 8.441
7.179
5.405
 CA
CA
C
 F1
C6
O
4gqq 1 P04746 98.59 0.0 X-RAY
 2012-10-24 CYS A:103 A:103 0.0 0.0 E -82.8 -176.0 0.0 0.0 0.0 HOH
 6.077
 C
 O
4gqr 1 P04746 98.59 0.0 X-RAY
 2012-10-24 CYS A:103 A:103 0.0 0.0 E -81.5 -179.5 0.0 0.0 0.0 MYC
HOH
 7.575
5.761
 C
C
 O13
O
4w93 1 P04746 98.59 0.0 X-RAY
 2015-07-15 CYS A:103 A:103 0.0 0.0 E -78.2 178.3 0.0 0.0 0.0 3L9
HOH
 8.303
5.583
 CA
C
 C1
O
4x9y 1 P04746 98.59 0.0 X-RAY
 2014-12-31 CYS A:103 A:103 0.0 0.0 E -83.8 179.4 0.0 0.0 0.0 HOH
 5.298
 HB2
 O
5e0f 1 P04746 98.59 0.0 X-RAY
 2016-09-07 CYS A:103 A:103 0.0 0.0 E -95.0 179.3 0.0 0.0 0.0 5J7
HOH
 6.699
5.097
 HA
HB2
 H201
O
5emy 1 P04746 98.59 0.0 X-RAY
 2016-07-06 CYS A:103 A:103 0.0 0.0 E -87.2 179.0 0.0 0.0 0.0 5QP
HOH
 5.924
5.356
 HA
HB2
 H61
O
5kez 1 P04746 98.59 0.0 X-RAY
 2017-03-29 CYS A:103 A:103 0.0 0.0 E -90.9 -178.1 0.0 0.0 0.0 HOH
 5.686
 C
 O
5u3a 1 P04746 98.59 0.0 X-RAY
 2017-12-06 CYS A:103 A:103 0.0 0.0 E -86.3 179.6 0.0 0.0 0.0 HOH
 5.277
 HB2
 O
5va9 1 P04746 98.59 0.0 X-RAY
 2018-03-28 CYS A:103 A:103 0.0 0.0 E -72.9 173.9 0.0 0.0 0.0 HOH
 7.457
 N
 O
CYS B:103 B:103 0.0 0.0 E -72.5 174.1 NA NA NA
6obx 1 P04746 98.59 0.0 X-RAY
 2020-02-12 CYS A:103 A:103 0.0 0.0 E -91.9 179.7 0.0 0.0 0.0 ZXU
MPD
HOH
 5.937
5.352
6.466
 HA
C
HA
 HE1
H11
O
6ocn 1 P04746 98.59 0.0 X-RAY
 2020-02-12 CYS A:103 A:103 0.0 0.0 E -87.2 -180.0 0.0 0.0 0.0 ZXY
HOH
 6.779
5.267
 HA
C
 H14
O
1xgz 1 P04746 98.39 0.0 X-RAY
 2005-05-24 CYS A:103 A:103 0.0 0.0 E -77.6 177.8 0.0 0.0 0.0 HOH
 2.878
 C
 O
1xh0 1 P04746 98.39 0.0 X-RAY
 2005-05-24 CYS A:103 A:103 0.0 0.0 E -74.9 -179.9 0.0 0.0 0.0 AAO
HOH
 5.185
5.547
 C
C
 O6A
O
1xh1 1 P04746 98.39 0.0 X-RAY
 2005-05-24 CYS A:103 A:103 0.0 0.0 E -84.3 175.9 0.0 0.0 0.0 HOH
 5.917
 C
 O
1xh2 1 P04746 98.39 0.0 X-RAY
 2005-05-24 CYS A:103 A:103 0.0 0.0 E -87.9 176.2 0.0 0.0 0.0 ARE
HOH
 5.738
6.105
 C
C
 C6A
O
3bak 1 P04746 98.39 0.0 X-RAY
 2008-03-25 CYS A:103 A:103 0.0 0.0 E -81.0 175.8 0.0 0.0 0.0 HOH
 5.698
 C
 O
3bax 1 P04746 98.39 0.0 X-RAY
 2008-03-25 CYS A:103 A:103 0.0 0.0 E -78.9 178.7 0.0 0.0 0.0 HOH
 5.779
 C
 O
3bay 1 P04746 98.39 0.0 X-RAY
 2008-03-25 CYS A:103 A:103 0.0 0.0 E -83.3 175.0 0.0 0.0 0.0 ARE
HOH
 5.755
5.954
 C
C
 C6A
O
1kgw 1 P04746 98.39 0.0 X-RAY
 2002-01-16 CYS A:103 A:103 0.0 0.0 E -92.9 173.5 0.0 0.0 0.0 HOH
 2.773
 SG
 O
2cpu 1 P04746 98.39 0.0 X-RAY
 2001-06-30 CYS A:103 A:103 0.0 0.0 E -86.4 -179.3 0.0 0.0 0.0 HOH
 5.911
 C
 O
3cpu 1 P04746 98.39 0.0 X-RAY
 2001-06-30 CYS A:103 A:103 0.0 0.0 E -96.5 179.2 0.0 0.0 0.0 GLC
GLC
HOH
 7.150
5.726
6.296
 CA
C
C
 C6
C6
O
5td4 1 P04746 98.39 0.0 X-RAY
 2016-11-02 CYS A:103 A:103 0.0 0.0 E -88.4 -176.1 0.0 0.0 0.0 GLC
GLC
GLC
GLC
HOH
 8.982
7.171
5.666
6.403
7.239
 CA
C
C
C
N
 C6
C6
O6
O6
O
1kgx 1 P04746 98.39 0.0 X-RAY
 2002-01-16 CYS A:103 A:103 0.0 0.0 E -84.8 179.1 0.0 0.0 0.0 HOH
 4.446
 SG
 O
1kbb 1 P04746 98.39 0.0 X-RAY
 2002-04-10 CYS A:103 A:103 0.0 0.0 E -87.3 -177.7 0.0 0.0 0.0 HOH
 7.192
 N
 O
1kgu 1 P04746 98.39 0.0 X-RAY
 2002-01-16 CYS A:103 A:103 0.0 0.0 E -89.4 179.9 0.0 0.0 0.0 HOH
 7.117
 N
 O
1kb3 1 P04746 98.39 0.0 X-RAY
 2002-05-01 CYS A:103 A:103 0.0 0.0 E -80.4 178.3 0.0 0.0 0.0 HOH
 6.095
 C
 O
1kbk 1 P04746 98.39 0.0 X-RAY
 2002-04-10 CYS A:103 A:103 0.0 0.0 E -89.6 178.6 0.0 0.0 0.0 HOH
 5.716
 C
 O
1c8q 1 P04745 97.58 0.0 X-RAY
 2001-06-13 CYS A:103 A:103 0.0 0.0 E -86.0 -178.0 0.0 0.0 0.0 HOH
 5.975
 C
 O
1mfv 1 P04745 97.58 0.0 X-RAY
 2002-11-20 CYS A:103 A:103 0.0 0.0 E -83.2 178.5 0.0 0.0 0.0 GLC
AGL
HMC
HMC
HOH
 7.235
5.899
8.576
8.915
5.630
 CA
C
C
CA
C
 C6
C6
C6
O7
O
1smd 1 P04745 97.58 0.0 X-RAY
 1996-07-11 CYS A:103 A:103 0.0 0.0 E -85.8 -180.0 0.0 0.0 0.0 HOH
 7.242
 N
 O
1xv8 1 P04745 97.58 0.0 X-RAY
 2005-10-11 CYS A:103 A:103 0.0 0.0 E -95.8 -178.9 0.0 0.0 0.0 HOH
 7.374
 CA
 O
CYS B:103 B:103 0.0 0.0 E -95.8 -178.9 0.0 0.0 0.0 HOH
 7.374
 CA
 O
1q4n 1 P04745 97.38 0.0 X-RAY
 2004-03-16 CYS A:103 X:103 0.0 0.0 E -83.2 177.1 0.0 0.0 0.0 TAM
HOH
 9.292
5.960
 CA
C
 O6
O
1z32 1 P04745 97.38 0.0 X-RAY
 2005-05-31 CYS A:103 X:103 0.0 0.0 E -90.0 177.7 0.0 0.0 0.0 GLC
HMC
HOH
 7.269
8.935
5.701
 C
CA
C
 C6
O7
O
1jxj 1 P04745 97.38 0.0 X-RAY
 2001-09-14 CYS A:103 A:103 0.0 0.0 E -97.3 -177.5 0.0 0.0 0.0 HOH
 6.033
 C
 O
1nm9 1 P04745 97.38 0.0 X-RAY
 2004-01-20 CYS A:103 A:103 0.0 0.0 E -83.7 -178.1 0.0 0.0 0.0 HMC
HOH
 8.920
5.732
 CA
C
 O7
O
3blk 1 P04745 97.38 0.0 X-RAY
 2008-11-25 CYS A:103 A:103 0.0 0.0 E -82.3 -178.0 0.0 0.0 0.0 GLC
AGL
HMC
HOH
 7.419
6.056
8.813
7.183
 C
C
CA
N
 C6
C6
O7
O
3blp 1 P04745 97.38 0.0 X-RAY
 2008-11-18 CYS A:103 X:103 0.0 0.0 E -88.9 177.9 0.0 0.0 0.0 GLC
AGL
HMC
HOH
 7.314
5.924
8.817
5.851
 CA
C
CA
C
 C6
C6
O7
O
1jxk 1 P04745 96.57 0.0 X-RAY
 2001-09-14 CYS A:103 A:103 0.0 0.0 E -90.6 179.1 0.0 0.0 0.0 HOH
 5.721
 C
 O
1mfu 1 P04745 96.57 0.0 X-RAY
 2002-11-20 CYS A:103 A:103 0.0 0.0 E -87.2 -179.9 0.0 0.0 0.0 GLC
AGL
HMC
HMC
HOH
 7.270
6.041
7.882
8.833
5.606
 C
C
O
CA
C
 C6
C6
O7
O7
O
3dhp 1 P04745 96.37 0.0 X-RAY
 2008-07-01 CYS A:103 A:103 0.0 0.0 E -78.5 177.9 0.0 0.0 0.0 GLC
HMC
HOH
 7.370
8.826
5.773
 CA
CA
C
 C6
O7
O
1kxq 1 P00690 87.1 0.0 X-RAY
 2002-06-19 CYS A:103 A:103 0.0 0.0 E -75.7 176.8 0.0 0.0 0.0 HOH
 5.301
 C
 O
CYS B:103 B:103 0.0 0.0 E -73.0 178.4 NA NA NA
CYS C:103 C:103 0.0 0.0 E -73.8 178.2 NA NA NA
CYS D:103 D:103 0.0 0.0 E -83.3 -179.7 NA NA NA
1kxt 1 P00690 87.1 0.0 X-RAY
 2002-06-19 CYS A:103 A:103 0.0 0.0 E -70.2 178.6 0.0 0.0 0.0 HOH
 4.879
 SG
 O
CYS C:103 C:103 0.0 0.0 E -62.7 175.2 NA NA NA
CYS E:103 E:103 0.0 0.0 E -57.6 -175.7 NA NA NA
1kxv 1 P00690 87.1 0.0 X-RAY
 2002-06-19 CYS A:103 A:103 0.0 0.0 E -78.4 178.9 0.0 0.0 0.0 HOH
 5.320
 CB
 O
CYS B:103 B:103 0.0 0.0 E -83.6 -174.8 NA NA NA
1dhk 1 P00690 87.1 0.0 X-RAY
 1997-12-24 CYS A:103 A:103 0.0 0.0 E -83.4 179.7 0.0 0.0 0.0 HOH
 5.449
 CB
 O
1ppi 1 P00690 87.1 0.0 X-RAY
 1995-05-24 CYS A:103 A:103 0.0 0.0 E -83.4 178.7 0.0 0.0 0.0 GLC
GLC
DAF
HOH
 7.203
5.003
8.880
5.582
 CA
C
CA
CB
 C6
O6
O7H
O
3l2l 1 P00690 86.9 0.0 X-RAY
 2010-04-14 CYS A:103 A:103 0.0 0.0 E -86.3 179.9 0.0 0.0 0.0 GLC
GLC
GLC
GLC
GLC
GLC
GLC
HOH
 8.813
7.924
6.114
6.358
8.354
9.884
4.941
4.246
 HG
HA
HA
C
C
O
C
HB2
 O2
H62
H62
H62
H62
H3
H61
O
3l2m 1 P00690 86.9 0.0 X-RAY
 2010-04-14 CYS A:103 A:103 0.0 0.0 E -86.6 -178.4 0.0 0.0 0.0 GLC
GLC
GLC
GLC
GLC
HOH
 7.264
8.616
6.428
8.929
8.546
4.383
 HB2
HG
HA
O
HA
HB2
 HO3
HO2
H62
H61
H62
O
1ua3 1 P00690 86.9 0.0 X-RAY
 2003-10-14 CYS A:103 A:103 0.0 0.0 E -86.0 -178.1 0.0 0.0 0.0 GLC
GLC
GLC
HOH
 9.280
7.241
5.560
5.415
 CA
C
C
CB
 O6
C6
O6
O
1vah 1 P00690 86.9 0.0 X-RAY
 2005-04-26 CYS A:103 A:103 0.0 0.0 E -73.3 -179.6 0.0 0.0 0.0 NPO
HOH
 8.035
6.214
 C
C
 C5
O
1jfh 1 P00690 86.9 0.0 X-RAY
 1998-12-02 CYS A:103 A:103 0.0 0.0 E -83.6 177.4 0.0 0.0 0.0 MA3
MA2
HG
HOH
 7.287
5.830
2.313
5.078
 C
C
SG
CB
 C6
O6
HG
O
1ose 1 P00690 86.69 0.0 X-RAY
 1997-04-01 CYS A:103 A:103 0.0 0.0 E -75.4 175.6 0.0 0.0 0.0 AC1
GLC
AC1
HOH
 8.958
7.303
5.839
5.536
 CA
C
C
CB
 O6B
C6
C6
O
1hx0 1 P00690 86.69 0.0 X-RAY
 2001-08-08 CYS A:103 A:103 0.0 0.0 E -80.8 -179.1 0.0 0.0 0.0 AC1
GLC
AC1
EDO
HOH
 9.023
7.356
5.800
6.563
5.400
 CA
CA
C
SG
CB
 O6B
C6
C6
O2
O
1wo2 1 P00690 86.69 0.0 X-RAY
 2005-03-15 CYS A:103 A:103 0.0 0.0 E -82.8 -179.3 0.0 0.0 0.0 BGC
GLC
GLC
EDO
HOH
 9.016
7.309
5.508
5.366
5.819
 CA
C
C
CB
C
 O6
C6
C6
O2
O
1bvn 1 P00690 86.69 0.0 X-RAY
 1998-09-23 CYS A:103 P:103 0.0 0.0 E -70.7 -169.3 0.0 0.0 0.0 HOH
 5.322
 O
 O
1pif 1 P00690 86.49 0.0 X-RAY
 1996-12-07 CYS A:103 A:103 0.0 0.0 E -77.9 -175.9 0.0 0.0 0.0 HOH
 5.900
 C
 O
1pig 1 P00690 86.49 0.0 X-RAY
 1996-12-07 CYS A:103 A:103 0.0 0.0 E -75.2 -178.6 0.0 0.0 0.0 GLC
AGL
HMC
HOH
 7.237
5.762
8.680
6.345
 C
C
CA
C
 C6
C6
O7
O
4x0n 1 P00690 86.49 0.0 X-RAY
 2015-11-25 CYS A:103 A:103 0.0 0.0 E -66.6 179.6 0.0 0.0 0.0 HOH
 7.026
 N
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p19961-f1 1 P19961 100.0 0.0 SER A:118 A:118 0.0 0.0 E -66.3 168.2
af-p04746-f1 1 P04746 98.83 0.0 CYS A:118 A:118 0.0 0.0 E -67.9 170.6
af-p0dte7-f1 1 P0DTE7 97.46 0.0 CYS A:118 A:118 0.0 0.0 E -68.1 172.5
af-p0dte8-f1 1 P0DTE8 97.46 0.0 CYS A:118 A:118 0.0 0.0 E -69.6 172.4
af-p0dub6-f1 1 P0DUB6 97.46 0.0 CYS A:118 A:118 0.0 0.0 E -63.5 170.6