Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 104115733 . G A CCDS782.1:NM_020978.4:c.364Gtg>Atg_NP_066188.1:p.122V>M Homo sapiens amylase, alpha 2B (pancreatic) (AMY2B), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3old 1 P04746 98.99 0.0 X-RAY
 2011-04-13 VAL A:107 A:107 37.0 0.239 S -64.3 138.1 37.0 0.239 0.0 GLC
GLC
HOH
 7.938
5.009
2.764
 CG2
CG2
O
 O6
O6
O
3ole 1 P04746 98.99 0.0 X-RAY
 2011-04-13 VAL A:107 A:107 37.0 0.239 S -64.4 137.0 37.0 0.239 0.0 GLC
G6D
ACI
HOH
 8.103
5.813
6.037
2.808
 CG2
CG2
N
O
 O6
C6
O6
O
3olg 1 P04746 98.99 0.0 X-RAY
 2011-04-13 VAL A:107 A:107 43.0 0.277 S -64.7 142.9 43.0 0.277 0.0 GLC
G6D
HSD
HOH
 7.952
6.175
6.112
2.618
 CG2
CG2
N
O
 O6
C6
O2
O
3oli 1 P04746 98.99 0.0 X-RAY
 2011-04-13 VAL A:107 A:107 36.0 0.232 S -66.5 138.2 36.0 0.232 0.0 GLC
G6D
HSD
HOH
 8.097
6.040
5.667
2.743
 CG2
CG2
N
O
 O6
C6
O1
O
6z8l 1 P04746 98.79 0.0 X-RAY
 2020-12-02 VAL A:107 A:107 38.0 0.245 S -65.9 138.1 38.0 0.245 0.0 GLC
GLC
GLC
HOH
 7.361
3.959
9.624
2.739
 HG21
HG23
HA
O
 H62
O6
HO1
O
1b2y 1 P04746 98.79 0.0 X-RAY
 2000-02-16 VAL A:107 A:107 41.0 0.265 S -84.7 148.7 41.0 0.265 0.0 GLC
G6D
HOH
 8.313
6.243
3.509
 CG2
CG2
CG1
 O6
C6
O
1bsi 1 P04746 98.59 0.0 X-RAY
 1999-05-18 VAL A:107 A:107 36.0 0.232 S -65.9 144.4 36.0 0.232 0.0 HOH
 4.133
 N
 O
1cpu 1 P04746 98.59 0.0 X-RAY
 1999-06-14 VAL A:107 A:107 36.0 0.232 S -58.3 141.5 36.0 0.232 0.0 GLC
GLC
HOH
 8.240
5.925
2.866
 CG2
CG2
O
 O6
C6
O
1hny 1 P04746 98.59 0.0 X-RAY
 1996-03-08 VAL A:107 A:107 41.0 0.265 S -84.4 150.6 41.0 0.265 0.0 HOH
 2.739
 O
 O
1u2y 1 P04746 98.59 0.0 X-RAY
 2004-09-07 VAL A:107 A:107 37.0 0.239 S -66.5 138.3 37.0 0.239 0.0 HOH
 4.326
 N
 O
1u30 1 P04746 98.59 0.0 X-RAY
 2004-09-07 VAL A:107 A:107 35.0 0.226 S -67.5 139.2 35.0 0.226 0.0 LAG
HOH
 4.283
3.890
 CG2
CG2
 OD6
O
1u33 1 P04746 98.59 0.0 X-RAY
 2004-09-07 VAL A:107 A:107 35.0 0.226 S -69.2 134.9 35.0 0.226 0.0 LM2
HOH
 4.547
2.728
 CG2
O
 OD6
O
1xcw 1 P04746 98.59 0.0 X-RAY
 2004-12-07 VAL A:107 A:107 36.0 0.232 S -62.6 136.4 36.0 0.232 0.0 HOH
 3.684
 CA
 O
1xcx 1 P04746 98.59 0.0 X-RAY
 2004-12-07 VAL A:107 A:107 36.0 0.232 S -72.8 138.9 36.0 0.232 0.0 HOH
 4.176
 O
 O
1xd0 1 P04746 98.59 0.0 X-RAY
 2004-12-07 VAL A:107 A:107 33.0 0.213 S -68.7 138.1 33.0 0.213 0.0 ARE
HOH
 5.760
4.487
 CG2
N
 C6A
O
1xd1 1 P04746 98.59 0.0 X-RAY
 2004-12-07 VAL A:107 A:107 35.0 0.226 S -68.8 141.5 35.0 0.226 0.0 6SA
HOH
 5.604
4.207
 CG2
O
 CV6
O
2qmk 1 P04746 98.59 0.0 X-RAY
 2008-03-25 VAL A:107 A:107 37.0 0.239 S -68.6 129.6 37.0 0.239 0.0 HOH
 3.723
 CG1
 O
2qv4 1 P04746 98.59 0.0 X-RAY
 2008-03-25 VAL A:107 A:107 38.0 0.245 S -67.1 137.0 38.0 0.245 0.0 QV4
HOH
 2.482
2.832
 N
O
 O4Q
O
3bai 1 P04746 98.59 0.0 X-RAY
 2008-03-25 VAL A:107 A:107 36.0 0.232 S -57.5 141.6 36.0 0.232 0.0 HOH
 2.773
 O
 O
3baj 1 P04746 98.59 0.0 X-RAY
 2008-03-25 VAL A:107 A:107 34.0 0.219 S -67.8 134.4 34.0 0.219 0.0 ARE
HOH
 5.853
3.890
 CG2
CA
 C6A
O
3baw 1 P04746 98.59 0.0 X-RAY
 2008-03-25 VAL A:107 A:107 38.0 0.245 S -62.6 136.9 38.0 0.245 0.0 HOH
 2.938
 O
 O
3ij7 1 P04746 98.59 0.0 X-RAY
 2009-10-27 VAL A:107 A:107 38.0 0.245 S -63.2 138.4 38.0 0.245 0.0 BGC
B8D
HOH
 7.784
4.992
3.575
 CG2
CG2
CG1
 O6
O6
O
3ij8 1 P04746 98.59 0.0 X-RAY
 2009-10-27 VAL A:107 A:107 38.0 0.245 S -62.1 138.7 38.0 0.245 0.0 HOH
 2.824
 O
 O
3ij9 1 P04746 98.59 0.0 X-RAY
 2009-10-27 VAL A:107 A:107 37.0 0.239 S -65.2 137.3 37.0 0.239 0.0 BGC
HOH
 8.080
2.710
 CG2
O
 O6
O
4gqq 1 P04746 98.59 0.0 X-RAY
 2012-10-24 VAL A:107 A:107 25.0 0.161 78.5 -3.3 25.0 0.161 0.0 HOH
 3.472
 N
 O
4gqr 1 P04746 98.59 0.0 X-RAY
 2012-10-24 VAL A:107 A:107 36.0 0.232 S -65.2 136.3 36.0 0.232 0.0 MYC
HOH
 7.368
2.800
 CG2
O
 O30
O
4w93 1 P04746 98.59 0.0 X-RAY
 2015-07-15 VAL A:107 A:107 40.0 0.258 S -66.6 137.7 40.0 0.258 0.0 HOH
 2.703
 O
 O
4x9y 1 P04746 98.59 0.0 X-RAY
 2014-12-31 VAL A:107 A:107 37.0 0.239 S -64.7 137.2 37.0 0.239 0.0 HOH
 2.761
 O
 O
5e0f 1 P04746 98.59 0.0 X-RAY
 2016-09-07 VAL A:107 A:107 39.0 0.252 S -62.6 137.0 39.0 0.252 0.0 5J7
HOH
 8.771
2.736
 HG21
O
 H23
O
5emy 1 P04746 98.59 0.0 X-RAY
 2016-07-06 VAL A:107 A:107 38.0 0.245 S -63.8 137.9 38.0 0.245 0.0 5QP
HOH
 7.550
2.816
 HG21
O
 O6
O
5kez 1 P04746 98.59 0.0 X-RAY
 2017-03-29 VAL A:107 A:107 37.0 0.239 S -69.4 139.7 37.0 0.239 0.0 HOH
 2.803
 O
 O
5u3a 1 P04746 98.59 0.0 X-RAY
 2017-12-06 VAL A:107 A:107 40.0 0.258 S -63.9 137.6 40.0 0.258 0.0 HOH
 2.771
 O
 O
5va9 1 P04746 98.59 0.0 X-RAY
 2018-03-28 VAL A:107 A:107 38.0 0.245 S -68.4 139.0 38.0 0.245 0.0 HOH
 3.865
 O
 O
VAL B:107 B:107 37.0 0.239 S -67.8 138.2 NA NA NA
6obx 1 P04746 98.59 0.0 X-RAY
 2020-02-12 VAL A:107 A:107 39.0 0.252 S -66.3 138.1 39.0 0.252 0.0 ZXU
MPD
HOH
 5.967
2.554
2.796
 HG23
HG23
O
 HH
H51
O
6ocn 1 P04746 98.59 0.0 X-RAY
 2020-02-12 VAL A:107 A:107 40.0 0.258 S -64.0 137.8 40.0 0.258 0.0 ZXY
HOH
 8.373
2.752
 HG22
O
 HG2
O
1xgz 1 P04746 98.39 0.0 X-RAY
 2005-05-24 VAL A:107 A:107 38.0 0.245 S -73.1 135.8 38.0 0.245 0.0 HOH
 2.771
 O
 O
1xh0 1 P04746 98.39 0.0 X-RAY
 2005-05-24 VAL A:107 A:107 36.0 0.232 S -62.3 135.9 36.0 0.232 0.0 AAO
HOH
 5.815
3.071
 CG2
CG2
 C6A
O
1xh1 1 P04746 98.39 0.0 X-RAY
 2005-05-24 VAL A:107 A:107 38.0 0.245 S -61.4 138.4 38.0 0.245 0.0 HOH
 2.757
 O
 O
1xh2 1 P04746 98.39 0.0 X-RAY
 2005-05-24 VAL A:107 A:107 37.0 0.239 S -58.6 138.8 37.0 0.239 0.0 ARE
HOH
 5.753
2.702
 CG2
O
 C6A
O
3bak 1 P04746 98.39 0.0 X-RAY
 2008-03-25 VAL A:107 A:107 37.0 0.239 S -61.3 141.4 37.0 0.239 0.0 HOH
 2.808
 O
 O
3bax 1 P04746 98.39 0.0 X-RAY
 2008-03-25 VAL A:107 A:107 38.0 0.245 S -65.1 136.2 38.0 0.245 0.0 HOH
 2.891
 O
 O
3bay 1 P04746 98.39 0.0 X-RAY
 2008-03-25 VAL A:107 A:107 36.0 0.232 S -57.4 140.6 36.0 0.232 0.0 ARE
HOH
 5.821
2.929
 CG2
O
 C6A
O
1kgw 1 P04746 98.39 0.0 X-RAY
 2002-01-16 VAL A:107 A:107 38.0 0.245 S -67.9 145.4 38.0 0.245 0.0 HOH
 3.781
 CG1
 O
2cpu 1 P04746 98.39 0.0 X-RAY
 2001-06-30 VAL A:107 A:107 38.0 0.245 S -60.1 148.2 38.0 0.245 0.0 HOH
 4.064
 N
 O
3cpu 1 P04746 98.39 0.0 X-RAY
 2001-06-30 VAL A:107 A:107 40.0 0.258 S -65.7 142.9 40.0 0.258 0.0 GLC
GLC
HOH
 8.281
6.101
4.614
 CG2
CG2
N
 O6
C6
O
5td4 1 P04746 98.39 0.0 X-RAY
 2016-11-02 VAL A:107 A:107 37.0 0.239 S -68.7 144.1 37.0 0.239 0.0 GLC
GLC
GLC
GLC
HOH
 7.164
8.104
5.000
5.034
4.889
 N
CG2
CG2
N
O
 O1
O6
O6
O6
O
1kgx 1 P04746 98.39 0.0 X-RAY
 2002-01-16 VAL A:107 A:107 37.0 0.239 S -68.4 141.3 37.0 0.239 0.0 HOH
 4.584
 C
 O
1kbb 1 P04746 98.39 0.0 X-RAY
 2002-04-10 VAL A:107 A:107 40.0 0.258 S -77.9 141.5 40.0 0.258 0.0 HOH
 4.112
 CG1
 O
1kgu 1 P04746 98.39 0.0 X-RAY
 2002-01-16 VAL A:107 A:107 37.0 0.239 S -76.6 140.1 37.0 0.239 0.0 HOH
 3.852
 CG1
 O
1kb3 1 P04746 98.39 0.0 X-RAY
 2002-05-01 VAL A:107 A:107 37.0 0.239 S -64.7 144.9 37.0 0.239 0.0 HOH
 4.456
 N
 O
1kbk 1 P04746 98.39 0.0 X-RAY
 2002-04-10 VAL A:107 A:107 33.0 0.213 S -71.7 141.0 33.0 0.213 0.0 HOH
 4.377
 N
 O
1c8q 1 P04745 97.58 0.0 X-RAY
 2001-06-13 VAL A:107 A:107 40.0 0.258 S -64.4 137.0 40.0 0.258 0.0 HOH
 2.613
 O
 O
1mfv 1 P04745 97.58 0.0 X-RAY
 2002-11-20 VAL A:107 A:107 38.0 0.245 S -63.0 139.5 38.0 0.245 0.0 GLC
AGL
HMC
HOH
 8.124
6.168
6.802
2.704
 CG2
CG2
N
O
 O6
C6
C7
O
1smd 1 P04745 97.58 0.0 X-RAY
 1996-07-11 VAL A:107 A:107 40.0 0.258 S -66.5 160.8 40.0 0.258 0.0 HOH
 8.087
 CG2
 O
1xv8 1 P04745 97.58 0.0 X-RAY
 2005-10-11 VAL A:107 A:107 36.0 0.232 S -45.2 137.6 36.0 0.232 0.0 HOH
 5.427
 CG1
 O
VAL B:107 B:107 36.0 0.232 S -45.1 137.7 36.0 0.232 0.0 HOH
 5.427
 CG1
 O
1q4n 1 P04745 97.38 0.0 X-RAY
 2004-03-16 VAL A:107 X:107 41.0 0.265 S -72.5 140.7 41.0 0.265 0.0 HOH
 2.907
 O
 O
1z32 1 P04745 97.38 0.0 X-RAY
 2005-05-31 VAL A:107 X:107 38.0 0.245 S -66.3 135.6 38.0 0.245 0.0 GLC
HOH
 8.261
2.758
 CG2
O
 O6
O
1jxj 1 P04745 97.38 0.0 X-RAY
 2001-09-14 VAL A:107 A:107 33.0 0.213 S -70.7 140.6 33.0 0.213 0.0 HOH
 2.708
 O
 O
1nm9 1 P04745 97.38 0.0 X-RAY
 2004-01-20 VAL A:107 A:107 33.0 0.213 S -66.1 139.0 33.0 0.213 0.0 HOH
 2.824
 O
 O
3blk 1 P04745 97.38 0.0 X-RAY
 2008-11-25 VAL A:107 A:107 40.0 0.258 S -61.2 136.3 40.0 0.258 0.0 GLC
AGL
HOH
 8.228
6.425
2.763
 CG2
CG2
O
 O6
C6
O
3blp 1 P04745 97.38 0.0 X-RAY
 2008-11-18 VAL A:107 X:107 38.0 0.245 S -61.4 132.3 38.0 0.245 0.0 GLC
AGL
HOH
 8.200
6.084
2.747
 CG2
CG2
O
 O6
C6
O
1jxk 1 P04745 96.57 0.0 X-RAY
 2001-09-14 VAL A:107 A:107 39.0 0.252 S -63.4 135.2 39.0 0.252 0.0 HOH
 2.766
 O
 O
1mfu 1 P04745 96.57 0.0 X-RAY
 2002-11-20 VAL A:107 A:107 38.0 0.245 S -70.0 139.5 38.0 0.245 0.0 GLC
AGL
HMC
HOH
 8.107
6.271
6.609
2.749
 CG2
CG2
N
O
 O6
C6
O7
O
3dhp 1 P04745 96.37 0.0 X-RAY
 2008-07-01 VAL A:107 A:107 38.0 0.245 S -65.1 138.8 38.0 0.245 0.0 GLC
HOH
 8.264
2.767
 CG2
O
 O6
O
1kxq 1 P00690 87.1 0.0 X-RAY
 2002-06-19 ALA A:107 A:107 24.0 0.209 S -63.6 142.1 23.0 0.2 0.009 H:None:0.009
 HOH
 2.695
 O
 O
ALA B:107 B:107 23.0 0.2 S -63.6 140.4 NA NA NA
ALA C:107 C:107 24.0 0.209 S -61.0 145.8 NA NA NA
ALA D:107 D:107 28.0 0.243 -65.3 146.7 NA NA NA
1kxt 1 P00690 87.1 0.0 X-RAY
 2002-06-19 ALA A:107 A:107 24.0 0.209 -75.1 158.5 24.0 0.209 0.0 HOH
 2.603
 O
 O
ALA C:107 C:107 32.0 0.278 S -68.4 144.2 NA NA NA
ALA E:107 E:107 23.0 0.2 -90.0 134.7 NA NA NA
1kxv 1 P00690 87.1 0.0 X-RAY
 2002-06-19 ALA A:107 A:107 28.0 0.243 S -70.6 146.0 28.0 0.243 0.0 HOH
 2.803
 O
 O
ALA B:107 B:107 31.0 0.27 S -70.9 153.7 NA NA NA
1dhk 1 P00690 87.1 0.0 X-RAY
 1997-12-24 ALA A:107 A:107 26.0 0.226 S -68.5 147.6 26.0 0.226 0.0 HOH
 1.738
 O
 H1
1ppi 1 P00690 87.1 0.0 X-RAY
 1995-05-24 ALA A:107 A:107 31.0 0.27 S -68.0 153.4 31.0 0.27 0.0 GLC
GLC
HOH
 9.608
7.217
2.833
 CB
N
O
 O6
C6
O
3l2l 1 P00690 86.9 0.0 X-RAY
 2010-04-14 ALA A:107 A:107 29.0 0.252 S -71.0 151.6 29.0 0.252 0.0 GLC
GLC
GLC
GLC
GLC
GLC
GLC
HOH
 3.318
8.710
9.350
6.404
6.731
9.100
2.693
2.695
 HA
HA
HB1
HB1
H
H
H
HB1
 HO2
HO2
H61
O6
H62
H5
H61
O
3l2m 1 P00690 86.9 0.0 X-RAY
 2010-04-14 ALA A:107 A:107 30.0 0.261 S -74.4 148.9 30.0 0.261 0.0 GLC
GLC
GLC
GLC
GLC
GLC
HOH
 8.556
6.948
2.858
3.240
6.140
8.042
2.776
 HA
HA
HA
HA
HB1
H
O
 HO2
O4
O3
HO2
HO6
H61
O
1ua3 1 P00690 86.9 0.0 X-RAY
 2003-10-14 ALA A:107 A:107 28.0 0.243 -71.3 153.9 28.0 0.243 0.0 GLC
GLC
HOH
 9.878
6.130
2.713
 CB
N
O
 O6
O6
O
1vah 1 P00690 86.9 0.0 X-RAY
 2005-04-26 ALA A:107 A:107 28.0 0.243 -88.4 154.4 28.0 0.243 0.0 NPO
HOH
 9.761
4.265
 CB
N
 OH
O
1jfh 1 P00690 86.9 0.0 X-RAY
 1998-12-02 ALA A:107 A:107 35.0 0.304 -86.3 156.5 35.0 0.304 0.0 MA3
MA2
HG
HOH
 9.718
5.692
5.136
3.213
 CB
N
CB
CB
 O6
O6
HG
O
1ose 1 P00690 86.69 0.0 X-RAY
 1997-04-01 ALA A:107 A:107 28.0 0.243 S -59.8 154.8 28.0 0.243 0.0 AC1
HOH
 4.947
3.473
 N
N
 O6B
O
1hx0 1 P00690 86.69 0.0 X-RAY
 2001-08-08 ALA A:107 A:107 27.0 0.235 -74.3 153.9 27.0 0.235 0.0 GLC
AC1
EDO
HOH
 9.966
3.987
4.339
2.705
 CB
N
CB
O
 O6
O6B
O2
O
1wo2 1 P00690 86.69 0.0 X-RAY
 2005-03-15 ALA A:107 A:107 28.0 0.243 -67.3 152.6 28.0 0.243 0.0 GLC
GLC
EDO
HOH
 9.829
5.991
3.827
2.780
 CB
N
CB
O
 O6
O6
O2
O
1bvn 1 P00690 86.69 0.0 X-RAY
 1998-09-23 ALA A:107 P:107 31.0 0.27 S -66.2 145.7 31.0 0.27 0.0 HOH
 3.101
 O
 O
1pif 1 P00690 86.49 0.0 X-RAY
 1996-12-07 ALA A:107 A:107 32.0 0.278 S -57.7 148.4 32.0 0.278 0.0 HOH
 2.488
 O
 O
1pig 1 P00690 86.49 0.0 X-RAY
 1996-12-07 ALA A:107 A:107 32.0 0.278 S -62.6 154.7 32.0 0.278 0.0 GLC
AGL
HOH
 9.901
7.222
2.537
 CB
N
O
 O6
C6
O
4x0n 1 P00690 86.49 0.0 X-RAY
 2015-11-25 ALA A:107 A:107 34.0 0.296 -74.0 153.0 34.0 0.296 0.0 HOH
 2.433
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p19961-f1 1 P19961 100.0 0.0 VAL A:122 A:122 37.0 0.239 S -65.7 132.6
af-p04746-f1 1 P04746 98.83 0.0 VAL A:122 A:122 38.0 0.245 S -68.3 135.4
af-p0dte7-f1 1 P0DTE7 97.46 0.0 VAL A:122 A:122 38.0 0.245 S -65.9 133.7
af-p0dte8-f1 1 P0DTE8 97.46 0.0 VAL A:122 A:122 37.0 0.239 S -66.1 134.2
af-p0dub6-f1 1 P0DUB6 97.46 0.0 VAL A:122 A:122 38.0 0.245 S -63.8 135.8