Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 104116381 . T A CCDS782.1:NM_020978.4:c.565Tat>Aat_NP_066188.1:p.189Y>N Homo sapiens amylase, alpha 2B (pancreatic) (AMY2B), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3old 1 P04746 98.99 0.0 X-RAY
 2011-04-13 TYR A:174 A:174 87.0 0.378 H -62.2 -46.9 87.0 0.378 0.0 GLC
GLC
GLC
HOH
 3.321
3.312
6.162
2.919
 CD2
CE2
OH
OH
 O3
C2
C1
O
3ole 1 P04746 98.99 0.0 X-RAY
 2011-04-13 TYR A:174 A:174 84.0 0.365 H -61.3 -48.5 84.0 0.365 0.0 GLC
GLC
GLC
HOH
 3.358
3.320
6.269
2.807
 CD2
CE2
OH
OH
 O3
C2
C1
O
3olg 1 P04746 98.99 0.0 X-RAY
 2011-04-13 TYR A:174 A:174 86.0 0.374 H -65.6 -47.7 86.0 0.374 0.0 BGC
GLC
GLC
GLC
HOH
 6.147
3.159
3.256
6.218
3.066
 CB
CD2
CZ
OH
OH
 O4
O3
C1
C1
O
3oli 1 P04746 98.99 0.0 X-RAY
 2011-04-13 TYR A:174 A:174 90.0 0.391 H -61.7 -49.1 90.0 0.391 0.0 GLC
GLC
GLC
HOH
 3.383
3.335
6.186
2.805
 CD2
CE2
OH
OH
 O3
C2
C1
O
6z8l 1 P04746 98.79 0.0 X-RAY
 2020-12-02 TYR A:174 A:174 89.0 0.387 H -58.2 -47.3 89.0 0.387 0.0 HOH
 2.072
 H
 O
1b2y 1 P04746 98.79 0.0 X-RAY
 2000-02-16 TYR A:174 A:174 94.0 0.409 H -65.2 -45.3 94.0 0.409 0.0 HOH
 5.988
 N
 O
1bsi 1 P04746 98.59 0.0 X-RAY
 1999-05-18 TYR A:174 A:174 90.0 0.391 H -59.8 -45.1 90.0 0.391 0.0 HOH
 2.957
 N
 O
1cpu 1 P04746 98.59 0.0 X-RAY
 1999-06-14 TYR A:174 A:174 88.0 0.383 H -61.1 -46.5 88.0 0.383 0.0 HOH
 3.018
 OH
 O
1hny 1 P04746 98.59 0.0 X-RAY
 1996-03-08 TYR A:174 A:174 95.0 0.413 H -64.1 -44.9 95.0 0.413 0.0 HOH
 3.262
 N
 O
1u2y 1 P04746 98.59 0.0 X-RAY
 2004-09-07 TYR A:174 A:174 87.0 0.378 H -57.3 -48.5 87.0 0.378 0.0 HOH
 2.834
 N
 O
1u30 1 P04746 98.59 0.0 X-RAY
 2004-09-07 TYR A:174 A:174 91.0 0.396 H -62.5 -48.0 91.0 0.396 0.0 HOH
 3.037
 N
 O
1u33 1 P04746 98.59 0.0 X-RAY
 2004-09-07 TYR A:174 A:174 92.0 0.4 H -61.4 -48.0 92.0 0.4 0.0 HOH
 3.169
 N
 O
1xcw 1 P04746 98.59 0.0 X-RAY
 2004-12-07 TYR A:174 A:174 95.0 0.413 H -56.6 -47.2 95.0 0.413 0.0 HOH
 4.756
 N
 O
1xcx 1 P04746 98.59 0.0 X-RAY
 2004-12-07 TYR A:174 A:174 89.0 0.387 H -58.0 -50.8 89.0 0.387 0.0 HOH
 2.964
 N
 O
1xd0 1 P04746 98.59 0.0 X-RAY
 2004-12-07 TYR A:174 A:174 92.0 0.4 H -56.7 -50.5 92.0 0.4 0.0 HOH
 4.108
 CE2
 O
1xd1 1 P04746 98.59 0.0 X-RAY
 2004-12-07 TYR A:174 A:174 89.0 0.387 H -55.1 -48.4 89.0 0.387 0.0 HOH
 5.053
 N
 O
2qmk 1 P04746 98.59 0.0 X-RAY
 2008-03-25 TYR A:174 A:174 90.0 0.391 H -58.0 -47.2 90.0 0.391 0.0 HOH
 3.152
 N
 O
2qv4 1 P04746 98.59 0.0 X-RAY
 2008-03-25 TYR A:174 A:174 91.0 0.396 H -63.1 -45.6 91.0 0.396 0.0 HOH
 3.047
 N
 O
3bai 1 P04746 98.59 0.0 X-RAY
 2008-03-25 TYR A:174 A:174 87.0 0.378 H -61.5 -47.8 87.0 0.378 0.0 HOH
 3.149
 N
 O
3baj 1 P04746 98.59 0.0 X-RAY
 2008-03-25 TYR A:174 A:174 89.0 0.387 H -58.2 -48.3 89.0 0.387 0.0 HOH
 3.064
 N
 O
3baw 1 P04746 98.59 0.0 X-RAY
 2008-03-25 TYR A:174 A:174 89.0 0.387 H -58.5 -51.1 89.0 0.387 0.0 HOH
 3.096
 N
 O
3ij7 1 P04746 98.59 0.0 X-RAY
 2009-10-27 TYR A:174 A:174 91.0 0.396 H -59.9 -47.6 91.0 0.396 0.0 HOH
 3.216
 N
 O
3ij8 1 P04746 98.59 0.0 X-RAY
 2009-10-27 TYR A:174 A:174 91.0 0.396 H -58.6 -48.6 91.0 0.396 0.0 HOH
 2.873
 N
 O
3ij9 1 P04746 98.59 0.0 X-RAY
 2009-10-27 TYR A:174 A:174 93.0 0.404 H -60.2 -47.9 93.0 0.404 0.0 HOH
 2.859
 OH
 O
4gqq 1 P04746 98.59 0.0 X-RAY
 2012-10-24 TYR A:174 A:174 95.0 0.413 H -64.1 -43.8 95.0 0.413 0.0 HOH
 3.380
 N
 O
4gqr 1 P04746 98.59 0.0 X-RAY
 2012-10-24 TYR A:174 A:174 88.0 0.383 H -60.9 -47.0 88.0 0.383 0.0 HOH
 3.058
 N
 O
4w93 1 P04746 98.59 0.0 X-RAY
 2015-07-15 TYR A:174 A:174 89.0 0.387 H -62.2 -48.4 89.0 0.387 0.0 HOH
 2.857
 N
 O
4x9y 1 P04746 98.59 0.0 X-RAY
 2014-12-31 TYR A:174 A:174 90.0 0.391 H -59.1 -48.0 90.0 0.391 0.0 HOH
 2.044
 H
 O
5e0f 1 P04746 98.59 0.0 X-RAY
 2016-09-07 TYR A:174 A:174 91.0 0.396 H -58.5 -48.4 91.0 0.396 0.0 HOH
 2.131
 H
 O
5emy 1 P04746 98.59 0.0 X-RAY
 2016-07-06 TYR A:174 A:174 92.0 0.4 H -59.0 -47.3 92.0 0.4 0.0 HOH
 2.084
 H
 O
5kez 1 P04746 98.59 0.0 X-RAY
 2017-03-29 TYR A:174 A:174 91.0 0.396 H -60.0 -45.3 91.0 0.396 0.0 HOH
 2.880
 N
 O
5u3a 1 P04746 98.59 0.0 X-RAY
 2017-12-06 TYR A:174 A:174 91.0 0.396 H -60.4 -47.0 91.0 0.396 0.0 HOH
 2.048
 H
 O
5va9 1 P04746 98.59 0.0 X-RAY
 2018-03-28 TYR A:174 A:174 86.0 0.374 H -62.2 -46.1 86.0 0.374 0.0 HOH
 3.798
 CE2
 O
TYR B:174 B:174 93.0 0.404 H -62.4 -45.7 NA NA NA
6obx 1 P04746 98.59 0.0 X-RAY
 2020-02-12 TYR A:174 A:174 92.0 0.4 H -58.7 -48.0 92.0 0.4 0.0 HOH
 2.068
 H
 O
6ocn 1 P04746 98.59 0.0 X-RAY
 2020-02-12 TYR A:174 A:174 91.0 0.396 H -59.1 -48.2 91.0 0.396 0.0 HOH
 2.069
 H
 O
1xgz 1 P04746 98.39 0.0 X-RAY
 2005-05-24 TYR A:174 A:174 88.0 0.383 H -58.0 -49.3 88.0 0.383 0.0 HOH
 3.012
 N
 O
1xh0 1 P04746 98.39 0.0 X-RAY
 2005-05-24 TYR A:174 A:174 93.0 0.404 H -57.8 -48.5 93.0 0.404 0.0 HOH
 2.650
 N
 O
1xh1 1 P04746 98.39 0.0 X-RAY
 2005-05-24 TYR A:174 A:174 87.0 0.378 H -59.1 -47.6 87.0 0.378 0.0 HOH
 3.177
 N
 O
1xh2 1 P04746 98.39 0.0 X-RAY
 2005-05-24 TYR A:174 A:174 89.0 0.387 H -59.2 -46.7 89.0 0.387 0.0 HOH
 3.224
 N
 O
3bak 1 P04746 98.39 0.0 X-RAY
 2008-03-25 TYR A:174 A:174 88.0 0.383 H -61.3 -49.6 88.0 0.383 0.0 HOH
 3.001
 N
 O
3bax 1 P04746 98.39 0.0 X-RAY
 2008-03-25 TYR A:174 A:174 88.0 0.383 H -61.4 -49.5 88.0 0.383 0.0 HOH
 2.936
 OH
 O
3bay 1 P04746 98.39 0.0 X-RAY
 2008-03-25 TYR A:174 A:174 89.0 0.387 H -64.9 -44.0 89.0 0.387 0.0 HOH
 4.496
 CE2
 O
1kgw 1 P04746 98.39 0.0 X-RAY
 2002-01-16 TYR A:174 A:174 89.0 0.387 H -63.5 -48.7 89.0 0.387 0.0 HOH
 3.174
 N
 O
2cpu 1 P04746 98.39 0.0 X-RAY
 2001-06-30 TYR A:174 A:174 87.0 0.378 H -55.1 -49.8 87.0 0.378 0.0 HOH
 4.102
 CD2
 O
3cpu 1 P04746 98.39 0.0 X-RAY
 2001-06-30 TYR A:174 A:174 88.0 0.383 H -61.6 -46.4 88.0 0.383 0.0 HOH
 3.462
 N
 O
5td4 1 P04746 98.39 0.0 X-RAY
 2016-11-02 TYR A:174 A:174 86.0 0.374 H -69.9 -44.0 86.0 0.374 0.0 GLC
GLC
GLC
GLC
HOH
 6.550
3.472
3.492
6.122
2.883
 CB
CD2
CZ
OH
N
 O4
O3
C1
C1
O
1kgx 1 P04746 98.39 0.0 X-RAY
 2002-01-16 TYR A:174 A:174 90.0 0.391 H -57.1 -48.3 90.0 0.391 0.0 HOH
 2.971
 N
 O
1kbb 1 P04746 98.39 0.0 X-RAY
 2002-04-10 TYR A:174 A:174 92.0 0.4 H -63.8 -47.6 92.0 0.4 0.0 HOH
 4.010
 CD2
 O
1kgu 1 P04746 98.39 0.0 X-RAY
 2002-01-16 TYR A:174 A:174 88.0 0.383 H -62.9 -50.2 88.0 0.383 0.0 HOH
 3.186
 N
 O
1kb3 1 P04746 98.39 0.0 X-RAY
 2002-05-01 TYR A:174 A:174 89.0 0.387 H -59.3 -46.8 89.0 0.387 0.0 HOH
 2.993
 N
 O
1kbk 1 P04746 98.39 0.0 X-RAY
 2002-04-10 TYR A:174 A:174 93.0 0.404 H -58.0 -50.4 93.0 0.404 0.0 HOH
 2.790
 N
 O
1c8q 1 P04745 97.58 0.0 X-RAY
 2001-06-13 TYR A:174 A:174 89.0 0.387 H -64.7 -47.7 89.0 0.387 0.0 HOH
 3.078
 N
 O
1mfv 1 P04745 97.58 0.0 X-RAY
 2002-11-20 TYR A:174 A:174 88.0 0.383 H -62.4 -46.3 88.0 0.383 0.0 HOH
 3.000
 N
 O
1smd 1 P04745 97.58 0.0 X-RAY
 1996-07-11 TYR A:174 A:174 91.0 0.396 H -61.4 -53.7 91.0 0.396 0.0 HOH
 4.293
 CD2
 O
1xv8 1 P04745 97.58 0.0 X-RAY
 2005-10-11 TYR A:174 A:174 82.0 0.357 H -52.9 -46.6 82.0 0.357 0.0 HOH
 6.436
 O
 O
TYR B:174 B:174 84.0 0.365 H -52.9 -46.6 84.0 0.365 0.0 HOH
 6.436
 O
 O
1q4n 1 P04745 97.38 0.0 X-RAY
 2004-03-16 TYR A:174 X:174 90.0 0.391 H -63.3 -49.1 90.0 0.391 0.0 HOH
 2.913
 N
 O
1z32 1 P04745 97.38 0.0 X-RAY
 2005-05-31 TYR A:174 X:174 89.0 0.387 H -60.2 -47.8 89.0 0.387 0.0 HOH
 3.006
 N
 O
1jxj 1 P04745 97.38 0.0 X-RAY
 2001-09-14 TYR A:174 A:174 95.0 0.413 H -64.5 -44.3 95.0 0.413 0.0 HOH
 2.765
 OH
 O
1nm9 1 P04745 97.38 0.0 X-RAY
 2004-01-20 TYR A:174 A:174 92.0 0.4 H -60.6 -48.3 92.0 0.4 0.0 HOH
 2.945
 N
 O
3blk 1 P04745 97.38 0.0 X-RAY
 2008-11-25 TYR A:174 A:174 92.0 0.4 H -57.4 -50.8 92.0 0.4 0.0 HOH
 2.981
 N
 O
3blp 1 P04745 97.38 0.0 X-RAY
 2008-11-18 TYR A:174 X:174 91.0 0.396 H -58.3 -46.6 91.0 0.396 0.0 HOH
 2.905
 N
 O
1jxk 1 P04745 96.57 0.0 X-RAY
 2001-09-14 TYR A:174 A:174 90.0 0.391 H -62.4 -46.2 90.0 0.391 0.0 HOH
 3.541
 CE2
 O
1mfu 1 P04745 96.57 0.0 X-RAY
 2002-11-20 TYR A:174 A:174 89.0 0.387 H -61.9 -47.7 89.0 0.387 0.0 GLC
HOH
 3.478
2.764
 CE1
OH
 O3
O
3dhp 1 P04745 96.37 0.0 X-RAY
 2008-07-01 TYR A:174 A:174 91.0 0.396 H -59.7 -47.1 91.0 0.396 0.0 HOH
 2.947
 N
 O
1kxq 1 P00690 87.1 0.0 X-RAY
 2002-06-19 TYR A:174 A:174 94.0 0.409 H -62.0 -47.8 94.0 0.409 0.0 HOH
 2.953
 N
 O
TYR B:174 B:174 89.0 0.387 H -61.9 -47.4 NA NA NA
TYR C:174 C:174 95.0 0.413 H -60.7 -44.7 NA NA NA
TYR D:174 D:174 89.0 0.387 H -60.3 -46.7 NA NA NA
1kxt 1 P00690 87.1 0.0 X-RAY
 2002-06-19 TYR A:174 A:174 95.0 0.413 H -55.5 -43.1 95.0 0.413 0.0 HOH
 2.812
 OH
 O
TYR C:174 C:174 90.0 0.391 H -54.2 -47.4 NA NA NA
TYR E:174 E:174 103.0 0.448 H -64.3 -44.0 NA NA NA
1kxv 1 P00690 87.1 0.0 X-RAY
 2002-06-19 TYR A:174 A:174 94.0 0.409 H -62.1 -44.4 94.0 0.409 0.0 HOH
 2.729
 O
 O
TYR B:174 B:174 90.0 0.391 H -61.5 -45.3 NA NA NA
1dhk 1 P00690 87.1 0.0 X-RAY
 1997-12-24 TYR A:174 A:174 91.0 0.396 H -62.4 -50.1 91.0 0.396 0.0 HOH
 1.983
 H
 H2
1ppi 1 P00690 87.1 0.0 X-RAY
 1995-05-24 TYR A:174 A:174 99.0 0.43 H -58.2 -48.9 99.0 0.43 0.0 HOH
 3.556
 CA
 O
3l2l 1 P00690 86.9 0.0 X-RAY
 2010-04-14 TYR A:174 A:174 96.0 0.417 H -59.9 -43.1 96.0 0.417 0.0 HOH
 2.202
 H
 O
3l2m 1 P00690 86.9 0.0 X-RAY
 2010-04-14 TYR A:174 A:174 97.0 0.422 H -55.9 -41.2 97.0 0.422 0.0 GLC
GLC
GLC
GLC
GLC
HOH
 9.382
5.107
2.681
2.991
7.837
2.086
 HH
HH
OH
CG
HB2
H
 O4
H61
H2
H1
H1
O
1ua3 1 P00690 86.9 0.0 X-RAY
 2003-10-14 TYR A:174 A:174 90.0 0.391 H -55.9 -47.1 90.0 0.391 0.0 EDO
EDO
HOH
 3.458
3.690
2.863
 CE2
CD2
N
 C1
C1
O
1vah 1 P00690 86.9 0.0 X-RAY
 2005-04-26 TYR A:174 A:174 103.0 0.448 H -57.5 -52.3 103.0 0.448 0.0 HOH
 4.811
 N
 O
1jfh 1 P00690 86.9 0.0 X-RAY
 1998-12-02 TYR A:174 A:174 99.0 0.43 H -57.0 -50.3 99.0 0.43 0.0 HOH
 3.368
 CA
 O
1ose 1 P00690 86.69 0.0 X-RAY
 1997-04-01 TYR A:174 A:174 89.0 0.387 H -59.0 -53.4 89.0 0.387 0.0 HOH
 3.310
 N
 O
1hx0 1 P00690 86.69 0.0 X-RAY
 2001-08-08 TYR A:174 A:174 92.0 0.4 H -57.4 -47.5 92.0 0.4 0.0 CL
HOH
 9.967
3.049
 N
N
 CL
O
1wo2 1 P00690 86.69 0.0 X-RAY
 2005-03-15 TYR A:174 A:174 92.0 0.4 H -62.9 -46.0 92.0 0.4 0.0 HOH
 2.879
 N
 O
1bvn 1 P00690 86.69 0.0 X-RAY
 1998-09-23 TYR A:174 P:174 104.0 0.452 H -66.1 -48.0 104.0 0.452 0.0 HOH
 3.041
 N
 O
1pif 1 P00690 86.49 0.0 X-RAY
 1996-12-07 TYR A:174 A:174 98.0 0.426 H -67.0 -42.5 98.0 0.426 0.0 HOH
 3.611
 CE2
 O
1pig 1 P00690 86.49 0.0 X-RAY
 1996-12-07 TYR A:174 A:174 81.0 0.352 H -62.2 -49.9 81.0 0.352 0.0 HOH
 5.079
 N
 O
4x0n 1 P00690 86.49 0.0 X-RAY
 2015-11-25 TYR A:174 A:174 84.0 0.365 H -63.4 -46.8 84.0 0.365 0.0 HOH
 2.955
 N
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p19961-f1 1 P19961 100.0 0.0 TYR A:189 A:189 97.0 0.422 H -58.8 -53.7
af-p04746-f1 1 P04746 98.83 0.0 TYR A:189 A:189 91.0 0.396 H -59.3 -53.6
af-p0dte7-f1 1 P0DTE7 97.46 0.0 TYR A:189 A:189 97.0 0.422 H -58.0 -52.5
af-p0dte8-f1 1 P0DTE8 97.46 0.0 TYR A:189 A:189 98.0 0.426 H -57.8 -52.9
af-p0dub6-f1 1 P0DUB6 97.46 0.0 TYR A:189 A:189 91.0 0.396 H -57.6 -50.1