Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 104116402 . G A CCDS782.1:NM_020978.4:c.586Gaa>Aaa_NP_066188.1:p.196E>K Homo sapiens amylase, alpha 2B (pancreatic) (AMY2B), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3old 1 P04746 98.99 0.0 X-RAY
 2011-04-13 GLU A:181 A:181 115.0 0.605 H -59.3 -42.4 115.0 0.605 0.0 GLC
HOH
 9.733
2.598
 OE1
OE1
 O6
O
3ole 1 P04746 98.99 0.0 X-RAY
 2011-04-13 GLU A:181 A:181 115.0 0.605 H -60.8 -43.9 115.0 0.605 0.0 GLC
HOH
 9.814
2.631
 OE1
OE2
 O6
O
3olg 1 P04746 98.99 0.0 X-RAY
 2011-04-13 GLU A:181 A:181 113.0 0.595 H -61.4 -45.7 113.0 0.595 0.0 GLC
HOH
 9.857
2.509
 OE1
OE1
 O6
O
3oli 1 P04746 98.99 0.0 X-RAY
 2011-04-13 GLU A:181 A:181 115.0 0.605 H -60.0 -43.1 115.0 0.605 0.0 GLC
HOH
 9.905
2.599
 OE1
OE2
 O6
O
6z8l 1 P04746 98.79 0.0 X-RAY
 2020-12-02 GLU A:181 A:181 114.0 0.6 H -56.8 -46.4 114.0 0.6 0.0 HOH
 2.596
 HB3
 O
1b2y 1 P04746 98.79 0.0 X-RAY
 2000-02-16 GLU A:181 A:181 115.0 0.605 H -63.6 -46.2 115.0 0.605 0.0 HOH
 7.334
 OE1
 O
1bsi 1 P04746 98.59 0.0 X-RAY
 1999-05-18 GLU A:181 A:181 117.0 0.616 H -60.6 -40.6 117.0 0.616 0.0 HOH
 2.824
 OE1
 O
1cpu 1 P04746 98.59 0.0 X-RAY
 1999-06-14 GLU A:181 A:181 112.0 0.589 H -59.0 -41.7 112.0 0.589 0.0 HOH
 2.622
 OE1
 O
1hny 1 P04746 98.59 0.0 X-RAY
 1996-03-08 GLU A:181 A:181 116.0 0.611 H -62.2 -47.1 116.0 0.611 0.0 HOH
 2.821
 OE2
 O
1u2y 1 P04746 98.59 0.0 X-RAY
 2004-09-07 GLU A:181 A:181 116.0 0.611 H -59.6 -42.6 116.0 0.611 0.0 HOH
 2.654
 O
 O
1u30 1 P04746 98.59 0.0 X-RAY
 2004-09-07 GLU A:181 A:181 116.0 0.611 H -64.5 -42.3 116.0 0.611 0.0 HOH
 2.600
 O
 O
1u33 1 P04746 98.59 0.0 X-RAY
 2004-09-07 GLU A:181 A:181 111.0 0.584 H -62.3 -45.0 111.0 0.584 0.0 HOH
 2.761
 OE1
 O
1xcw 1 P04746 98.59 0.0 X-RAY
 2004-12-07 GLU A:181 A:181 116.0 0.611 H -57.3 -52.1 116.0 0.611 0.0 HOH
 2.797
 O
 O
1xcx 1 P04746 98.59 0.0 X-RAY
 2004-12-07 GLU A:181 A:181 115.0 0.605 H -58.4 -41.3 115.0 0.605 0.0 HOH
 2.654
 O
 O
1xd0 1 P04746 98.59 0.0 X-RAY
 2004-12-07 GLU A:181 A:181 114.0 0.6 H -61.7 -40.8 114.0 0.6 0.0 HOH
 2.563
 OE1
 O
1xd1 1 P04746 98.59 0.0 X-RAY
 2004-12-07 GLU A:181 A:181 118.0 0.621 H -59.8 -43.6 118.0 0.621 0.0 HOH
 2.640
 O
 O
2qmk 1 P04746 98.59 0.0 X-RAY
 2008-03-25 GLU A:181 A:181 115.0 0.605 H -58.6 -39.8 115.0 0.605 0.0 HOH
 2.671
 O
 O
2qv4 1 P04746 98.59 0.0 X-RAY
 2008-03-25 GLU A:181 A:181 116.0 0.611 H -61.8 -39.7 116.0 0.611 0.0 HOH
 2.565
 OE2
 O
3bai 1 P04746 98.59 0.0 X-RAY
 2008-03-25 GLU A:181 A:181 115.0 0.605 H -59.3 -43.4 115.0 0.605 0.0 HOH
 2.645
 O
 O
3baj 1 P04746 98.59 0.0 X-RAY
 2008-03-25 GLU A:181 A:181 115.0 0.605 H -60.2 -47.9 115.0 0.605 0.0 HOH
 2.619
 O
 O
3baw 1 P04746 98.59 0.0 X-RAY
 2008-03-25 GLU A:181 A:181 119.0 0.626 H -63.0 -43.1 119.0 0.626 0.0 HOH
 2.776
 OE1
 O
3ij7 1 P04746 98.59 0.0 X-RAY
 2009-10-27 GLU A:181 A:181 114.0 0.6 H -58.5 -42.9 114.0 0.6 0.0 HOH
 2.592
 O
 O
3ij8 1 P04746 98.59 0.0 X-RAY
 2009-10-27 GLU A:181 A:181 113.0 0.595 H -60.1 -43.8 113.0 0.595 0.0 HOH
 2.620
 OE2
 O
3ij9 1 P04746 98.59 0.0 X-RAY
 2009-10-27 GLU A:181 A:181 112.0 0.589 H -59.6 -42.8 112.0 0.589 0.0 HOH
 2.613
 O
 O
4gqq 1 P04746 98.59 0.0 X-RAY
 2012-10-24 GLU A:181 A:181 114.0 0.6 H -63.5 -43.6 114.0 0.6 0.0 HOH
 2.776
 O
 O
4gqr 1 P04746 98.59 0.0 X-RAY
 2012-10-24 GLU A:181 A:181 115.0 0.605 H -60.3 -43.5 115.0 0.605 0.0 HOH
 2.599
 OE2
 O
4w93 1 P04746 98.59 0.0 X-RAY
 2015-07-15 GLU A:181 A:181 115.0 0.605 H -58.8 -46.1 115.0 0.605 0.0 HOH
 2.541
 OE1
 O
4x9y 1 P04746 98.59 0.0 X-RAY
 2014-12-31 GLU A:181 A:181 116.0 0.611 H -59.6 -46.0 116.0 0.611 0.0 HOH
 2.640
 OE2
 O
5e0f 1 P04746 98.59 0.0 X-RAY
 2016-09-07 GLU A:181 A:181 114.0 0.6 H -60.7 -46.2 114.0 0.6 0.0 HOH
 2.670
 OE2
 O
5emy 1 P04746 98.59 0.0 X-RAY
 2016-07-06 GLU A:181 A:181 113.0 0.595 H -61.0 -45.1 113.0 0.595 0.0 HOH
 2.632
 OE2
 O
5kez 1 P04746 98.59 0.0 X-RAY
 2017-03-29 GLU A:181 A:181 115.0 0.605 H -59.3 -42.6 115.0 0.605 0.0 HOH
 2.747
 O
 O
5u3a 1 P04746 98.59 0.0 X-RAY
 2017-12-06 GLU A:181 A:181 115.0 0.605 H -60.0 -46.1 115.0 0.605 0.0 HOH
 2.689
 OE1
 O
5va9 1 P04746 98.59 0.0 X-RAY
 2018-03-28 GLU A:181 A:181 117.0 0.616 H -57.5 -46.8 117.0 0.616 0.0 HOH
 8.326
 OE1
 O
GLU B:181 B:181 115.0 0.605 H -57.0 -47.4 NA NA NA
6obx 1 P04746 98.59 0.0 X-RAY
 2020-02-12 GLU A:181 A:181 115.0 0.605 H -60.0 -44.7 115.0 0.605 0.0 HOH
 2.639
 HG2
 O
6ocn 1 P04746 98.59 0.0 X-RAY
 2020-02-12 GLU A:181 A:181 115.0 0.605 H -60.3 -45.2 115.0 0.605 0.0 HOH
 2.669
 HG2
 O
1xgz 1 P04746 98.39 0.0 X-RAY
 2005-05-24 GLU A:181 A:181 114.0 0.6 H -61.2 -41.8 114.0 0.6 0.0 HOH
 2.602
 OE1
 O
1xh0 1 P04746 98.39 0.0 X-RAY
 2005-05-24 GLU A:181 A:181 114.0 0.6 H -57.7 -45.2 114.0 0.6 0.0 HOH
 2.601
 OE1
 O
1xh1 1 P04746 98.39 0.0 X-RAY
 2005-05-24 GLU A:181 A:181 114.0 0.6 H -56.5 -44.4 114.0 0.6 0.0 HOH
 2.612
 O
 O
1xh2 1 P04746 98.39 0.0 X-RAY
 2005-05-24 GLU A:181 A:181 116.0 0.611 H -56.7 -41.8 116.0 0.611 0.0 HOH
 2.530
 O
 O
3bak 1 P04746 98.39 0.0 X-RAY
 2008-03-25 GLU A:181 A:181 116.0 0.611 H -60.8 -44.2 116.0 0.611 0.0 HOH
 2.680
 O
 O
3bax 1 P04746 98.39 0.0 X-RAY
 2008-03-25 GLU A:181 A:181 115.0 0.605 H -60.7 -42.9 115.0 0.605 0.0 HOH
 2.668
 O
 O
3bay 1 P04746 98.39 0.0 X-RAY
 2008-03-25 GLU A:181 A:181 114.0 0.6 H -60.2 -43.2 114.0 0.6 0.0 HOH
 2.654
 O
 O
1kgw 1 P04746 98.39 0.0 X-RAY
 2002-01-16 GLU A:181 A:181 114.0 0.6 H -65.6 -39.0 114.0 0.6 0.0 HOH
 3.257
 OE2
 O
2cpu 1 P04746 98.39 0.0 X-RAY
 2001-06-30 GLU A:181 A:181 116.0 0.611 H -60.1 -41.5 116.0 0.611 0.0 HOH
 2.577
 O
 O
3cpu 1 P04746 98.39 0.0 X-RAY
 2001-06-30 GLU A:181 A:181 114.0 0.6 H -65.8 -41.3 114.0 0.6 0.0 HOH
 2.852
 OE1
 O
5td4 1 P04746 98.39 0.0 X-RAY
 2016-11-02 GLU A:181 A:181 117.0 0.616 H -60.8 -44.3 117.0 0.616 0.0 HOH
 2.695
 OE1
 O
1kgx 1 P04746 98.39 0.0 X-RAY
 2002-01-16 GLU A:181 A:181 116.0 0.611 H -59.4 -37.8 116.0 0.611 0.0 HOH
 2.720
 OE2
 O
1kbb 1 P04746 98.39 0.0 X-RAY
 2002-04-10 GLU A:181 A:181 116.0 0.611 H -61.8 -43.4 116.0 0.611 0.0 HOH
 2.665
 O
 O
1kgu 1 P04746 98.39 0.0 X-RAY
 2002-01-16 GLU A:181 A:181 113.0 0.595 H -64.2 -39.2 113.0 0.595 0.0 HOH
 2.834
 OE2
 O
1kb3 1 P04746 98.39 0.0 X-RAY
 2002-05-01 GLU A:181 A:181 115.0 0.605 H -59.8 -40.0 115.0 0.605 0.0 HOH
 2.633
 O
 O
1kbk 1 P04746 98.39 0.0 X-RAY
 2002-04-10 GLU A:181 A:181 117.0 0.616 H -57.4 -43.4 117.0 0.616 0.0 HOH
 2.665
 OE2
 O
1c8q 1 P04745 97.58 0.0 X-RAY
 2001-06-13 GLU A:181 A:181 109.0 0.574 H -58.8 -47.5 109.0 0.574 0.0 HOH
 2.584
 O
 O
1mfv 1 P04745 97.58 0.0 X-RAY
 2002-11-20 GLU A:181 A:181 114.0 0.6 H -62.8 -46.1 114.0 0.6 0.0 HOH
 2.615
 O
 O
1smd 1 P04745 97.58 0.0 X-RAY
 1996-07-11 GLU A:181 A:181 108.0 0.568 H -58.5 -51.3 108.0 0.568 0.0 HOH
 2.695
 OE1
 O
1xv8 1 P04745 97.58 0.0 X-RAY
 2005-10-11 GLU A:181 A:181 117.0 0.616 H -61.0 -44.7 117.0 0.616 0.0 HOH
 4.247
 N
 O
GLU B:181 B:181 115.0 0.605 H -61.0 -44.7 115.0 0.605 0.0 HOH
 4.247
 N
 O
1q4n 1 P04745 97.38 0.0 X-RAY
 2004-03-16 GLU A:181 X:181 114.0 0.6 H -61.1 -43.5 114.0 0.6 0.0 HOH
 2.674
 OE1
 O
1z32 1 P04745 97.38 0.0 X-RAY
 2005-05-31 GLU A:181 X:181 115.0 0.605 H -56.5 -46.8 115.0 0.605 0.0 HOH
 2.688
 OE1
 O
1jxj 1 P04745 97.38 0.0 X-RAY
 2001-09-14 GLU A:181 A:181 111.0 0.584 H -55.5 -48.5 111.0 0.584 0.0 HOH
 2.611
 OE1
 O
1nm9 1 P04745 97.38 0.0 X-RAY
 2004-01-20 GLU A:181 A:181 114.0 0.6 H -57.3 -48.1 114.0 0.6 0.0 HOH
 2.646
 O
 O
3blk 1 P04745 97.38 0.0 X-RAY
 2008-11-25 GLU A:181 A:181 118.0 0.621 H -55.2 -46.5 118.0 0.621 0.0 HOH
 2.547
 O
 O
3blp 1 P04745 97.38 0.0 X-RAY
 2008-11-18 GLU A:181 X:181 114.0 0.6 H -58.8 -45.8 114.0 0.6 0.0 HOH
 2.772
 O
 O
1jxk 1 P04745 96.57 0.0 X-RAY
 2001-09-14 GLU A:181 A:181 112.0 0.589 H -57.4 -47.1 112.0 0.589 0.0 HOH
 2.665
 OE2
 O
1mfu 1 P04745 96.57 0.0 X-RAY
 2002-11-20 GLU A:181 A:181 111.0 0.584 H -56.4 -48.7 111.0 0.584 0.0 GLC
HOH
 9.596
2.731
 OE1
OE1
 O3
O
3dhp 1 P04745 96.37 0.0 X-RAY
 2008-07-01 GLU A:181 A:181 116.0 0.611 H -59.8 -46.0 116.0 0.611 0.0 HOH
 2.694
 OE1
 O
1kxq 1 P00690 87.1 0.0 X-RAY
 2002-06-19 ASP A:181 A:181 101.0 0.673 H -62.7 -40.1 101.0 0.673 0.0 HOH
 2.610
 OD2
 O
ASP B:181 B:181 98.0 0.653 H -66.3 -39.8 NA NA NA
ASP C:181 C:181 102.0 0.68 H -61.6 -40.6 NA NA NA
ASP D:181 D:181 102.0 0.68 H -61.9 -39.9 NA NA NA
1kxt 1 P00690 87.1 0.0 X-RAY
 2002-06-19 ASP A:181 A:181 99.0 0.66 H -56.5 -43.4 99.0 0.66 0.0 HOH
 2.483
 OD1
 O
ASP C:181 C:181 94.0 0.627 H -66.7 -38.9 NA NA NA
ASP E:181 E:181 100.0 0.667 H -71.0 -38.1 NA NA NA
1kxv 1 P00690 87.1 0.0 X-RAY
 2002-06-19 ASP A:181 A:181 98.0 0.653 H -65.9 -38.9 98.0 0.653 0.0 HOH
 2.577
 OD2
 O
ASP B:181 B:181 97.0 0.647 H -66.4 -37.6 NA NA NA
1dhk 1 P00690 87.1 0.0 X-RAY
 1997-12-24 ASP A:181 A:181 98.0 0.653 H -64.8 -39.1 98.0 0.653 0.0 HOH
 3.081
 CB
 H2
1ppi 1 P00690 87.1 0.0 X-RAY
 1995-05-24 ASP A:181 A:181 105.0 0.7 H -65.8 -34.8 105.0 0.7 0.0 HOH
 2.827
 OD1
 O
3l2l 1 P00690 86.9 0.0 X-RAY
 2010-04-14 ASP A:181 A:181 100.0 0.667 H -61.0 -36.7 100.0 0.667 0.0 HOH
 2.596
 HA
 O
3l2m 1 P00690 86.9 0.0 X-RAY
 2010-04-14 ASP A:181 A:181 101.0 0.673 H -64.4 -38.9 101.0 0.673 0.0 HOH
 2.630
 HA
 O
1ua3 1 P00690 86.9 0.0 X-RAY
 2003-10-14 ASP A:181 A:181 97.0 0.647 H -63.6 -42.5 97.0 0.647 0.0 HOH
 2.694
 OD1
 O
1vah 1 P00690 86.9 0.0 X-RAY
 2005-04-26 ASP A:181 A:181 102.0 0.68 H -68.1 -33.5 102.0 0.68 0.0 HOH
 3.858
 CB
 O
1jfh 1 P00690 86.9 0.0 X-RAY
 1998-12-02 ASP A:181 A:181 107.0 0.713 H -66.7 -34.7 107.0 0.713 0.0 HOH
 2.653
 OD2
 O
1ose 1 P00690 86.69 0.0 X-RAY
 1997-04-01 ASP A:181 A:181 95.0 0.633 H -63.1 -35.7 95.0 0.633 0.0 HOH
 2.828
 OD1
 O
1hx0 1 P00690 86.69 0.0 X-RAY
 2001-08-08 ASP A:181 A:181 100.0 0.667 H -62.0 -40.9 100.0 0.667 0.0 HOH
 2.800
 OD1
 O
1wo2 1 P00690 86.69 0.0 X-RAY
 2005-03-15 ASP A:181 A:181 103.0 0.687 H -64.8 -41.0 103.0 0.687 0.0 HOH
 2.671
 O
 O
1bvn 1 P00690 86.69 0.0 X-RAY
 1998-09-23 ASP A:181 P:181 95.0 0.633 H -53.8 -48.7 95.0 0.633 0.0 HOH
 2.816
 O
 O
1pif 1 P00690 86.49 0.0 X-RAY
 1996-12-07 ASP A:181 A:181 100.0 0.667 H -62.4 -39.4 100.0 0.667 0.0 HOH
 2.949
 O
 O
1pig 1 P00690 86.49 0.0 X-RAY
 1996-12-07 ASP A:181 A:181 101.0 0.673 H -64.8 -42.4 101.0 0.673 0.0 HOH
 3.713
 CB
 O
4x0n 1 P00690 86.49 0.0 X-RAY
 2015-11-25 ASP A:181 A:181 98.0 0.653 H -63.8 -41.7 98.0 0.653 0.0 HOH
 2.655
 OD1
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p19961-f1 1 P19961 100.0 0.0 GLU A:196 A:196 116.0 0.611 H -58.2 -49.3
af-p04746-f1 1 P04746 98.83 0.0 GLU A:196 A:196 115.0 0.605 H -58.2 -49.3
af-p0dte7-f1 1 P0DTE7 97.46 0.0 GLU A:196 A:196 116.0 0.611 H -57.9 -49.0
af-p0dte8-f1 1 P0DTE8 97.46 0.0 GLU A:196 A:196 117.0 0.616 H -57.9 -49.1
af-p0dub6-f1 1 P0DUB6 97.46 0.0 GLU A:196 A:196 117.0 0.616 H -56.8 -50.1