Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 104116526 . T A CCDS782.1:NM_020978.4:c.710tTc>tAc_NP_066188.1:p.237F>Y Homo sapiens amylase, alpha 2B (pancreatic) (AMY2B), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3old 1 P04746 98.99 0.0 X-RAY
 2011-04-13 PHE A:222 A:222 9.0 0.043 S -117.5 152.8 9.0 0.043 0.0 HOH
 2.668
 O
 O
3ole 1 P04746 98.99 0.0 X-RAY
 2011-04-13 PHE A:222 A:222 9.0 0.043 S -117.0 151.7 9.0 0.043 0.0 HOH
 2.721
 O
 O
3olg 1 P04746 98.99 0.0 X-RAY
 2011-04-13 PHE A:222 A:222 8.0 0.038 S -115.1 152.2 8.0 0.038 0.0 HOH
 3.155
 O
 O
3oli 1 P04746 98.99 0.0 X-RAY
 2011-04-13 PHE A:222 A:222 9.0 0.043 S -120.2 148.1 9.0 0.043 0.0 MPD
HOH
 7.411
2.767
 N
O
 C1
O
6z8l 1 P04746 98.79 0.0 X-RAY
 2020-12-02 PHE A:222 A:222 7.0 0.033 S -122.2 141.3 7.0 0.033 0.0 HOH
 2.910
 O
 O
1b2y 1 P04746 98.79 0.0 X-RAY
 2000-02-16 PHE A:222 A:222 11.0 0.052 S -117.8 155.5 11.0 0.052 0.0 HOH
 3.647
 CE2
 O
1bsi 1 P04746 98.59 0.0 X-RAY
 1999-05-18 PHE A:222 A:222 8.0 0.038 S -122.2 148.3 8.0 0.038 0.0 HOH
 3.050
 O
 O
1cpu 1 P04746 98.59 0.0 X-RAY
 1999-06-14 PHE A:222 A:222 9.0 0.043 S -113.3 152.0 9.0 0.043 0.0 HOH
 2.764
 O
 O
1hny 1 P04746 98.59 0.0 X-RAY
 1996-03-08 PHE A:222 A:222 10.0 0.048 S -119.1 155.3 10.0 0.048 0.0 HOH
 2.879
 O
 O
1u2y 1 P04746 98.59 0.0 X-RAY
 2004-09-07 PHE A:222 A:222 10.0 0.048 S -118.8 152.1 10.0 0.048 0.0 HOH
 2.891
 O
 O
1u30 1 P04746 98.59 0.0 X-RAY
 2004-09-07 PHE A:222 A:222 9.0 0.043 S -117.5 147.9 9.0 0.043 0.0 HOH
 2.902
 O
 O
1u33 1 P04746 98.59 0.0 X-RAY
 2004-09-07 PHE A:222 A:222 11.0 0.052 S -115.8 151.9 11.0 0.052 0.0 HOH
 2.704
 O
 O
1xcw 1 P04746 98.59 0.0 X-RAY
 2004-12-07 PHE A:222 A:222 9.0 0.043 S -117.7 158.0 9.0 0.043 0.0 HOH
 3.490
 CE1
 O
1xcx 1 P04746 98.59 0.0 X-RAY
 2004-12-07 PHE A:222 A:222 9.0 0.043 S -119.2 149.0 9.0 0.043 0.0 HOH
 2.986
 O
 O
1xd0 1 P04746 98.59 0.0 X-RAY
 2004-12-07 PHE A:222 A:222 10.0 0.048 S -112.3 153.4 10.0 0.048 0.0 HOH
 3.834
 CE1
 O
1xd1 1 P04746 98.59 0.0 X-RAY
 2004-12-07 PHE A:222 A:222 9.0 0.043 S -121.0 151.0 9.0 0.043 0.0 HOH
 3.611
 CD2
 O
2qmk 1 P04746 98.59 0.0 X-RAY
 2008-03-25 PHE A:222 A:222 10.0 0.048 S -118.9 157.4 10.0 0.048 0.0 HOH
 3.090
 O
 O
2qv4 1 P04746 98.59 0.0 X-RAY
 2008-03-25 PHE A:222 A:222 9.0 0.043 S -117.5 153.9 9.0 0.043 0.0 HOH
 2.844
 O
 O
3bai 1 P04746 98.59 0.0 X-RAY
 2008-03-25 PHE A:222 A:222 10.0 0.048 S -119.9 153.4 10.0 0.048 0.0 HOH
 3.167
 O
 O
3baj 1 P04746 98.59 0.0 X-RAY
 2008-03-25 PHE A:222 A:222 10.0 0.048 S -123.3 152.1 10.0 0.048 0.0 HOH
 3.430
 O
 O
3baw 1 P04746 98.59 0.0 X-RAY
 2008-03-25 PHE A:222 A:222 9.0 0.043 S -120.2 157.6 9.0 0.043 0.0 NA
HOH
 7.160
2.993
 CD1
O
 NA
O
3ij7 1 P04746 98.59 0.0 X-RAY
 2009-10-27 PHE A:222 A:222 10.0 0.048 S -112.0 147.1 10.0 0.048 0.0 HOH
 2.703
 O
 O
3ij8 1 P04746 98.59 0.0 X-RAY
 2009-10-27 PHE A:222 A:222 10.0 0.048 S -113.6 147.7 10.0 0.048 0.0 HOH
 2.728
 O
 O
3ij9 1 P04746 98.59 0.0 X-RAY
 2009-10-27 PHE A:222 A:222 11.0 0.052 S -113.9 150.3 11.0 0.052 0.0 HOH
 2.718
 O
 O
4gqq 1 P04746 98.59 0.0 X-RAY
 2012-10-24 PHE A:222 A:222 5.0 0.024 S -113.2 145.5 5.0 0.024 0.0 HOH
 3.506
 CE1
 O
4gqr 1 P04746 98.59 0.0 X-RAY
 2012-10-24 PHE A:222 A:222 9.0 0.043 S -117.0 148.8 9.0 0.043 0.0 HOH
 2.732
 O
 O
4w93 1 P04746 98.59 0.0 X-RAY
 2015-07-15 PHE A:222 A:222 8.0 0.038 S -127.3 143.0 8.0 0.038 0.0 HOH
 2.826
 O
 O
4x9y 1 P04746 98.59 0.0 X-RAY
 2014-12-31 PHE A:222 A:222 9.0 0.043 S -121.7 148.2 9.0 0.043 0.0 HOH
 2.770
 O
 O
5e0f 1 P04746 98.59 0.0 X-RAY
 2016-09-07 PHE A:222 A:222 7.0 0.033 S -120.7 144.6 7.0 0.033 0.0 HOH
 2.824
 O
 O
5emy 1 P04746 98.59 0.0 X-RAY
 2016-07-06 PHE A:222 A:222 9.0 0.043 S -120.5 148.9 9.0 0.043 0.0 HOH
 2.807
 O
 O
5kez 1 P04746 98.59 0.0 X-RAY
 2017-03-29 PHE A:222 A:222 9.0 0.043 S -120.4 149.5 9.0 0.043 0.0 HOH
 2.805
 O
 O
5u3a 1 P04746 98.59 0.0 X-RAY
 2017-12-06 PHE A:222 A:222 9.0 0.043 S -120.4 148.3 9.0 0.043 0.0 HOH
 2.739
 O
 O
5va9 1 P04746 98.59 0.0 X-RAY
 2018-03-28 PHE A:222 A:222 9.0 0.043 S -130.7 148.2 9.0 0.043 0.0 HOH
 2.470
 O
 O
PHE B:222 B:222 7.0 0.033 S -130.8 150.8 NA NA NA
6obx 1 P04746 98.59 0.0 X-RAY
 2020-02-12 PHE A:222 A:222 9.0 0.043 S -120.2 148.7 9.0 0.043 0.0 HOH
 2.822
 O
 O
6ocn 1 P04746 98.59 0.0 X-RAY
 2020-02-12 PHE A:222 A:222 10.0 0.048 S -120.8 148.4 10.0 0.048 0.0 HOH
 2.779
 O
 O
1xgz 1 P04746 98.39 0.0 X-RAY
 2005-05-24 PHE A:222 A:222 9.0 0.043 S -115.9 150.4 9.0 0.043 0.0 HOH
 3.338
 O
 O
1xh0 1 P04746 98.39 0.0 X-RAY
 2005-05-24 PHE A:222 A:222 9.0 0.043 S -118.9 150.9 9.0 0.043 0.0 HOH
 3.032
 O
 O
1xh1 1 P04746 98.39 0.0 X-RAY
 2005-05-24 PHE A:222 A:222 9.0 0.043 S -121.5 150.3 9.0 0.043 0.0 HOH
 3.203
 O
 O
1xh2 1 P04746 98.39 0.0 X-RAY
 2005-05-24 PHE A:222 A:222 9.0 0.043 S -117.4 150.8 9.0 0.043 0.0 HOH
 3.465
 O
 O
3bak 1 P04746 98.39 0.0 X-RAY
 2008-03-25 PHE A:222 A:222 8.0 0.038 S -120.2 150.9 8.0 0.038 0.0 HOH
 3.165
 O
 O
3bax 1 P04746 98.39 0.0 X-RAY
 2008-03-25 PHE A:222 A:222 9.0 0.043 S -120.1 154.5 9.0 0.043 0.0 NA
HOH
 7.733
3.017
 CD1
O
 NA
O
3bay 1 P04746 98.39 0.0 X-RAY
 2008-03-25 PHE A:222 A:222 8.0 0.038 S -123.7 151.1 8.0 0.038 0.0 HOH
 3.282
 O
 O
1kgw 1 P04746 98.39 0.0 X-RAY
 2002-01-16 PHE A:222 A:222 9.0 0.043 S -119.3 150.1 9.0 0.043 0.0 HOH
 3.855
 CZ
 O
2cpu 1 P04746 98.39 0.0 X-RAY
 2001-06-30 PHE A:222 A:222 8.0 0.038 S -117.7 146.7 8.0 0.038 0.0 HOH
 3.664
 CE2
 O
3cpu 1 P04746 98.39 0.0 X-RAY
 2001-06-30 PHE A:222 A:222 10.0 0.048 S -114.4 155.5 10.0 0.048 0.0 HOH
 3.623
 CE1
 O
5td4 1 P04746 98.39 0.0 X-RAY
 2016-11-02 PHE A:222 A:222 10.0 0.048 S -117.1 149.8 10.0 0.048 0.0 HOH
 3.193
 O
 O
1kgx 1 P04746 98.39 0.0 X-RAY
 2002-01-16 PHE A:222 A:222 11.0 0.052 S -114.6 153.7 11.0 0.052 0.0 HOH
 3.046
 O
 O
1kbb 1 P04746 98.39 0.0 X-RAY
 2002-04-10 PHE A:222 A:222 10.0 0.048 S -118.6 152.9 10.0 0.048 0.0 HOH
 3.660
 CE2
 O
1kgu 1 P04746 98.39 0.0 X-RAY
 2002-01-16 PHE A:222 A:222 8.0 0.038 S -118.8 149.0 8.0 0.038 0.0 HOH
 3.629
 CE2
 O
1kb3 1 P04746 98.39 0.0 X-RAY
 2002-05-01 PHE A:222 A:222 10.0 0.048 S -119.8 152.1 10.0 0.048 0.0 HOH
 2.877
 O
 O
1kbk 1 P04746 98.39 0.0 X-RAY
 2002-04-10 PHE A:222 A:222 10.0 0.048 S -115.2 149.3 10.0 0.048 0.0 HOH
 2.936
 O
 O
1c8q 1 P04745 97.58 0.0 X-RAY
 2001-06-13 PHE A:222 A:222 6.0 0.029 S -110.5 142.7 6.0 0.029 0.0 HOH
 3.560
 CE2
 O
1mfv 1 P04745 97.58 0.0 X-RAY
 2002-11-20 PHE A:222 A:222 7.0 0.033 S -116.4 142.2 7.0 0.033 0.0 HOH
 3.642
 CE2
 O
1smd 1 P04745 97.58 0.0 X-RAY
 1996-07-11 PHE A:222 A:222 7.0 0.033 S -114.7 137.9 7.0 0.033 0.0 HOH
 3.620
 O
 O
1xv8 1 P04745 97.58 0.0 X-RAY
 2005-10-11 PHE A:222 A:222 11.0 0.052 S -116.2 160.2 11.0 0.052 0.0 HOH
 4.787
 O
 O
PHE B:222 B:222 12.0 0.057 S -116.2 160.2 12.0 0.057 0.0 HOH
 4.788
 O
 O
1q4n 1 P04745 97.38 0.0 X-RAY
 2004-03-16 PHE A:222 X:222 7.0 0.033 S -117.9 143.0 7.0 0.033 0.0 HOH
 3.528
 CE2
 O
1z32 1 P04745 97.38 0.0 X-RAY
 2005-05-31 PHE A:222 X:222 8.0 0.038 S -121.0 142.2 8.0 0.038 0.0 HOH
 2.812
 O
 O
1jxj 1 P04745 97.38 0.0 X-RAY
 2001-09-14 PHE A:222 A:222 7.0 0.033 S -121.0 146.5 7.0 0.033 0.0 HOH
 3.790
 CD2
 O
1nm9 1 P04745 97.38 0.0 X-RAY
 2004-01-20 PHE A:222 A:222 7.0 0.033 S -117.7 140.7 7.0 0.033 0.0 HOH
 3.562
 CE2
 O
3blk 1 P04745 97.38 0.0 X-RAY
 2008-11-25 PHE A:222 A:222 6.0 0.029 S -117.9 141.4 6.0 0.029 0.0 HOH
 3.681
 CE2
 O
3blp 1 P04745 97.38 0.0 X-RAY
 2008-11-18 PHE A:222 X:222 6.0 0.029 S -115.1 138.0 6.0 0.029 0.0 HOH
 3.760
 CE2
 O
1jxk 1 P04745 96.57 0.0 X-RAY
 2001-09-14 PHE A:222 A:222 9.0 0.043 S -118.9 144.8 9.0 0.043 0.0 HOH
 2.690
 O
 O
1mfu 1 P04745 96.57 0.0 X-RAY
 2002-11-20 PHE A:222 A:222 6.0 0.029 S -115.8 143.8 6.0 0.029 0.0 HOH
 2.986
 O
 O
3dhp 1 P04745 96.37 0.0 X-RAY
 2008-07-01 PHE A:222 A:222 7.0 0.033 S -119.7 141.9 7.0 0.033 0.0 HOH
 2.859
 O
 O
1kxq 1 P00690 87.1 0.0 X-RAY
 2002-06-19 PHE A:222 A:222 8.0 0.038 S -122.3 151.2 8.0 0.038 0.0 HOH
 3.017
 O
 O
PHE B:222 B:222 8.0 0.038 S -112.5 150.2 NA NA NA
PHE C:222 C:222 8.0 0.038 S -116.6 151.4 NA NA NA
PHE D:222 D:222 7.0 0.033 S -114.7 150.3 NA NA NA
1kxt 1 P00690 87.1 0.0 X-RAY
 2002-06-19 PHE A:222 A:222 9.0 0.043 S -120.0 153.8 9.0 0.043 0.0 HOH
 3.821
 CZ
 O
PHE C:222 C:222 9.0 0.043 S -123.4 163.1 NA NA NA
PHE E:222 E:222 11.0 0.052 S -123.0 156.3 NA NA NA
1kxv 1 P00690 87.1 0.0 X-RAY
 2002-06-19 PHE A:222 A:222 7.0 0.033 S -134.8 149.0 7.0 0.033 0.0 HOH
 3.572
 CE1
 O
PHE B:222 B:222 8.0 0.038 S -128.3 151.7 NA NA NA
1dhk 1 P00690 87.1 0.0 X-RAY
 1997-12-24 PHE A:222 A:222 6.0 0.029 S -118.6 148.2 6.0 0.029 0.0 HOH
 2.787
 CE2
 H1
1ppi 1 P00690 87.1 0.0 X-RAY
 1995-05-24 PHE A:222 A:222 7.0 0.033 S -120.5 150.8 7.0 0.033 0.0 HOH
 3.719
 CE2
 O
3l2l 1 P00690 86.9 0.0 X-RAY
 2010-04-14 PHE A:222 A:222 9.0 0.043 S -122.9 153.8 9.0 0.043 0.0 HOH
 2.587
 O
 O
3l2m 1 P00690 86.9 0.0 X-RAY
 2010-04-14 PHE A:222 A:222 8.0 0.038 S -119.9 152.9 8.0 0.038 0.0 HOH
 2.789
 O
 O
1ua3 1 P00690 86.9 0.0 X-RAY
 2003-10-14 PHE A:222 A:222 8.0 0.038 S -122.3 149.9 8.0 0.038 0.0 HOH
 2.858
 O
 O
1vah 1 P00690 86.9 0.0 X-RAY
 2005-04-26 PHE A:222 A:222 7.0 0.033 S -121.5 150.8 7.0 0.033 0.0 HOH
 3.628
 CE1
 O
1jfh 1 P00690 86.9 0.0 X-RAY
 1998-12-02 PHE A:222 A:222 8.0 0.038 S -118.8 150.7 8.0 0.038 0.0 HOH
 3.767
 CE2
 O
1ose 1 P00690 86.69 0.0 X-RAY
 1997-04-01 PHE A:222 A:222 8.0 0.038 S -111.7 152.2 8.0 0.038 0.0 HOH
 3.301
 O
 O
1hx0 1 P00690 86.69 0.0 X-RAY
 2001-08-08 PHE A:222 A:222 7.0 0.033 S -120.8 151.7 7.0 0.033 0.0 CL
HOH
 6.853
2.813
 O
O
 CL
O
1wo2 1 P00690 86.69 0.0 X-RAY
 2005-03-15 PHE A:222 A:222 7.0 0.033 S -123.6 153.9 7.0 0.033 0.0 HOH
 2.689
 O
 O
1bvn 1 P00690 86.69 0.0 X-RAY
 1998-09-23 PHE A:222 P:222 5.0 0.024 S -103.5 155.7 5.0 0.024 0.0 HOH
 3.229
 CE2
 O
1pif 1 P00690 86.49 0.0 X-RAY
 1996-12-07 PHE A:222 A:222 8.0 0.038 S -117.1 154.5 8.0 0.038 0.0 HOH
 3.888
 CE1
 O
1pig 1 P00690 86.49 0.0 X-RAY
 1996-12-07 PHE A:222 A:222 7.0 0.033 S -117.8 153.1 7.0 0.033 0.0 HOH
 3.658
 CZ
 O
4x0n 1 P00690 86.49 0.0 X-RAY
 2015-11-25 PHE A:222 A:222 8.0 0.038 S -120.9 150.8 8.0 0.038 0.0 HOH
 3.453
 CE1
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p19961-f1 1 P19961 100.0 0.0 PHE A:237 A:237 11.0 0.052 S -119.6 146.6
af-p04746-f1 1 P04746 98.83 0.0 PHE A:237 A:237 9.0 0.043 S -119.1 147.3
af-p0dte7-f1 1 P0DTE7 97.46 0.0 PHE A:237 A:237 10.0 0.048 S -120.9 146.7
af-p0dte8-f1 1 P0DTE8 97.46 0.0 PHE A:237 A:237 11.0 0.052 S -121.6 146.7
af-p0dub6-f1 1 P0DUB6 97.46 0.0 PHE A:237 A:237 9.0 0.043 S -122.2 146.9