Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 104116991 . A C CCDS782.1:NM_020978.4:c.854aAt>aCt_NP_066188.1:p.285N>T Homo sapiens amylase, alpha 2B (pancreatic) (AMY2B), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3old 1 P04746 98.99 0.0 X-RAY
 2011-04-13 ASN A:270 A:270 155.0 0.969 G 52.0 39.3 155.0 0.969 0.0 HOH
 2.671
 O
 O
3ole 1 P04746 98.99 0.0 X-RAY
 2011-04-13 ASN A:270 A:270 156.0 0.975 G 48.9 41.4 156.0 0.975 0.0 HOH
 2.760
 O
 O
3olg 1 P04746 98.99 0.0 X-RAY
 2011-04-13 ASN A:270 A:270 155.0 0.969 T 55.8 34.7 155.0 0.969 0.0 HOH
 2.619
 O
 O
3oli 1 P04746 98.99 0.0 X-RAY
 2011-04-13 ASN A:270 A:270 148.0 0.925 T 50.7 35.5 148.0 0.925 0.0 HOH
 2.882
 OD1
 O
6z8l 1 P04746 98.79 0.0 X-RAY
 2020-12-02 ASN A:270 A:270 150.0 0.938 T 58.1 31.0 150.0 0.938 0.0 GLC
GLC
HOH
 6.465
5.763
2.481
 O
HD22
OD1
 HO6
HO3
O
1b2y 1 P04746 98.79 0.0 X-RAY
 2000-02-16 ASN A:270 A:270 146.0 0.912 T 48.2 27.1 146.0 0.912 0.0 HOH
 3.869
 ND2
 O
1bsi 1 P04746 98.59 0.0 X-RAY
 1999-05-18 ASN A:270 A:270 132.0 0.825 G 45.1 54.4 132.0 0.825 0.0 HOH
 4.761
 C
 O
1cpu 1 P04746 98.59 0.0 X-RAY
 1999-06-14 ASN A:270 A:270 131.0 0.819 G 43.4 46.3 131.0 0.819 0.0 HOH
 4.328
 ND2
 O
1hny 1 P04746 98.59 0.0 X-RAY
 1996-03-08 ASN A:270 A:270 147.0 0.919 T 49.9 31.1 147.0 0.919 0.0 HOH
 3.232
 N
 O
1u2y 1 P04746 98.59 0.0 X-RAY
 2004-09-07 ASN A:270 A:270 133.0 0.831 G 39.5 55.2 133.0 0.831 0.0 HOH
 7.245
 C
 O
1u30 1 P04746 98.59 0.0 X-RAY
 2004-09-07 ASN A:270 A:270 153.0 0.956 G 55.4 30.0 153.0 0.956 0.0 HOH
 6.958
 C
 O
1u33 1 P04746 98.59 0.0 X-RAY
 2004-09-07 ASN A:270 A:270 151.0 0.944 G 58.7 25.3 151.0 0.944 0.0 HOH
 8.139
 C
 O
1xcw 1 P04746 98.59 0.0 X-RAY
 2004-12-07 ASN A:270 A:270 129.0 0.806 G 41.4 52.7 129.0 0.806 0.0 HOH
 7.287
 C
 O
1xcx 1 P04746 98.59 0.0 X-RAY
 2004-12-07 ASN A:270 A:270 134.0 0.838 G 41.7 61.7 134.0 0.838 0.0 HOH
 9.276
 N
 O
1xd0 1 P04746 98.59 0.0 X-RAY
 2004-12-07 ASN A:270 A:270 146.0 0.912 G 58.6 23.9 146.0 0.912 0.0 HOH
 9.071
 N
 O
1xd1 1 P04746 98.59 0.0 X-RAY
 2004-12-07 ASN A:270 A:270 136.0 0.85 T 30.6 66.3 136.0 0.85 0.0
2qmk 1 P04746 98.59 0.0 X-RAY
 2008-03-25 ASN A:270 A:270 160.0 1.0 G 49.8 40.8 160.0 1.0 0.0 HOH
 2.667
 ND2
 O
2qv4 1 P04746 98.59 0.0 X-RAY
 2008-03-25 ASN A:270 A:270 154.0 0.963 G 45.1 40.2 154.0 0.963 0.0 HOH
 2.868
 ND2
 O
3bai 1 P04746 98.59 0.0 X-RAY
 2008-03-25 ASN A:270 A:270 156.0 0.975 G 58.4 27.1 156.0 0.975 0.0 HOH
 3.000
 ND2
 O
3baj 1 P04746 98.59 0.0 X-RAY
 2008-03-25 ASN A:270 A:270 132.0 0.825 G 44.4 60.7 132.0 0.825 0.0 HOH
 3.389
 ND2
 O
3baw 1 P04746 98.59 0.0 X-RAY
 2008-03-25 ASN A:270 A:270 161.0 1.0 G 45.5 39.5 161.0 1.0 0.0 HOH
 2.692
 ND2
 O
3ij7 1 P04746 98.59 0.0 X-RAY
 2009-10-27 ASN A:270 A:270 126.0 0.787 G 46.4 38.7 126.0 0.787 0.0 HOH
 4.450
 O
 O
3ij8 1 P04746 98.59 0.0 X-RAY
 2009-10-27 ASN A:270 A:270 146.0 0.912 G 52.7 27.6 146.0 0.912 0.0 HOH
 2.985
 ND2
 O
3ij9 1 P04746 98.59 0.0 X-RAY
 2009-10-27 ASN A:270 A:270 130.0 0.812 G 41.7 56.5 130.0 0.812 0.0 HOH
 2.756
 OD1
 O
4gqq 1 P04746 98.59 0.0 X-RAY
 2012-10-24 ASN A:270 A:270 161.0 1.0 G 58.4 26.3 161.0 1.0 0.0 HOH
 2.667
 ND2
 O
4gqr 1 P04746 98.59 0.0 X-RAY
 2012-10-24 ASN A:270 A:270 140.0 0.875 G 43.0 46.7 140.0 0.875 0.0 HOH
 2.737
 OD1
 O
4w93 1 P04746 98.59 0.0 X-RAY
 2015-07-15 ASN A:270 A:270 147.0 0.919 T 64.4 29.4 147.0 0.919 0.0 HOH
 2.499
 O
 O
4x9y 1 P04746 98.59 0.0 X-RAY
 2014-12-31 ASN A:270 A:270 158.0 0.988 G 55.1 34.6 158.0 0.988 0.0 HOH
 2.064
 HD22
 O
5e0f 1 P04746 98.59 0.0 X-RAY
 2016-09-07 ASN A:270 A:270 153.0 0.956 T 52.6 33.3 153.0 0.956 0.0 HOH
 2.175
 H
 O
5emy 1 P04746 98.59 0.0 X-RAY
 2016-07-06 ASN A:270 A:270 158.0 0.988 G 56.7 34.8 158.0 0.988 0.0 HOH
 2.053
 HD22
 O
5kez 1 P04746 98.59 0.0 X-RAY
 2017-03-29 ASN A:270 A:270 141.0 0.881 T 56.8 34.3 141.0 0.881 0.0 HOH
 3.297
 N
 O
5u3a 1 P04746 98.59 0.0 X-RAY
 2017-12-06 ASN A:270 A:270 157.0 0.981 G 55.8 38.2 157.0 0.981 0.0 HOH
 3.023
 O
 O
5va9 1 P04746 98.59 0.0 X-RAY
 2018-03-28 ASN A:270 A:270 152.0 0.95 T 59.2 34.0 152.0 0.95 0.0 HOH
 9.981
 N
 O
ASN B:270 B:270 143.0 0.894 T 58.4 34.5 NA NA NA
6obx 1 P04746 98.59 0.0 X-RAY
 2020-02-12 ASN A:270 A:270 156.0 0.975 G 56.5 36.7 156.0 0.975 0.0 HOH
 2.102
 HD22
 O
6ocn 1 P04746 98.59 0.0 X-RAY
 2020-02-12 ASN A:270 A:270 156.0 0.975 G 56.4 37.1 156.0 0.975 0.0 HOH
 2.002
 HD22
 O
1xgz 1 P04746 98.39 0.0 X-RAY
 2005-05-24 ASN A:270 A:270 142.0 0.887 G 39.8 53.7 142.0 0.887 0.0 HOH
 2.962
 CB
 O
1xh0 1 P04746 98.39 0.0 X-RAY
 2005-05-24 ASN A:270 A:270 135.0 0.844 T 41.9 64.9 135.0 0.844 0.0 HOH
 3.111
 N
 O
1xh1 1 P04746 98.39 0.0 X-RAY
 2005-05-24 ASN A:270 A:270 144.0 0.9 G 49.9 52.7 144.0 0.9 0.0 HOH
 4.738
 C
 O
1xh2 1 P04746 98.39 0.0 X-RAY
 2005-05-24 ASN A:270 A:270 138.0 0.863 G 39.1 55.5 138.0 0.863 0.0 HOH
 3.831
 N
 O
3bak 1 P04746 98.39 0.0 X-RAY
 2008-03-25 ASN A:270 A:270 130.0 0.812 G 38.9 50.6 130.0 0.812 0.0 HOH
 3.067
 OD1
 O
3bax 1 P04746 98.39 0.0 X-RAY
 2008-03-25 ASN A:270 A:270 156.0 0.975 G 48.6 39.7 156.0 0.975 0.0 HOH
 2.840
 O
 O
3bay 1 P04746 98.39 0.0 X-RAY
 2008-03-25 ASN A:270 A:270 136.0 0.85 G 35.1 46.4 136.0 0.85 0.0 HOH
 7.642
 N
 O
1kgw 1 P04746 98.39 0.0 X-RAY
 2002-01-16 ASN A:270 A:270 125.0 0.781 T 49.0 51.3 125.0 0.781 0.0 HOH
 3.025
 N
 O
2cpu 1 P04746 98.39 0.0 X-RAY
 2001-06-30 ASN A:270 A:270 127.0 0.794 G 48.3 54.5 127.0 0.794 0.0 HOH
 3.372
 O
 O
3cpu 1 P04746 98.39 0.0 X-RAY
 2001-06-30 ASN A:270 A:270 117.0 0.731 T 30.3 52.6 117.0 0.731 0.0 HOH
 4.441
 OD1
 O
5td4 1 P04746 98.39 0.0 X-RAY
 2016-11-02 ASN A:270 A:270 157.0 0.981 T 62.1 25.9 157.0 0.981 0.0 HOH
 2.760
 O
 O
1kgx 1 P04746 98.39 0.0 X-RAY
 2002-01-16 ASN A:270 A:270 139.0 0.869 G 55.9 31.1 139.0 0.869 0.0 HOH
 4.532
 O
 O
1kbb 1 P04746 98.39 0.0 X-RAY
 2002-04-10 ASN A:270 A:270 144.0 0.9 T 49.4 31.0 144.0 0.9 0.0
1kgu 1 P04746 98.39 0.0 X-RAY
 2002-01-16 ASN A:270 A:270 153.0 0.956 T 17.9 38.2 153.0 0.956 0.0 HOH
 3.197
 N
 O
1kb3 1 P04746 98.39 0.0 X-RAY
 2002-05-01 ASN A:270 A:270 140.0 0.875 G 59.0 22.6 140.0 0.875 0.0 HOH
 3.051
 O
 O
1kbk 1 P04746 98.39 0.0 X-RAY
 2002-04-10 ASN A:270 A:270 147.0 0.919 G 55.7 30.0 147.0 0.919 0.0 HOH
 7.732
 C
 O
1c8q 1 P04745 97.58 0.0 X-RAY
 2001-06-13 ASN A:270 A:270 148.0 0.925 T 47.8 30.3 148.0 0.925 0.0 HOH
 2.573
 ND2
 O
1mfv 1 P04745 97.58 0.0 X-RAY
 2002-11-20 ASN A:270 A:270 148.0 0.925 T 54.5 32.1 148.0 0.925 0.0 BGC
GLC
AGL
HOH
 7.449
5.834
7.233
2.563
 O
O
OD1
ND2
 O6
O2
O2
O
1smd 1 P04745 97.58 0.0 X-RAY
 1996-07-11 ASN A:270 A:270 147.0 0.919 T 46.1 36.9 147.0 0.919 0.0 HOH
 3.087
 N
 O
1xv8 1 P04745 97.58 0.0 X-RAY
 2005-10-11 ASN A:270 A:270 137.0 0.856 T 48.6 54.1 106.0 0.662 0.194 B:P04745:0.194
 HOH
 5.505
 O
 O
ASN B:270 B:270 136.0 0.85 T 48.5 54.2 102.0 0.637 0.213 A:P04745:0.212
 HOH
 5.504
 O
 O
1q4n 1 P04745 97.38 0.0 X-RAY
 2004-03-16 ASN A:270 X:270 143.0 0.894 T 59.0 26.2 143.0 0.894 0.0 HOH
 2.724
 OD1
 O
1z32 1 P04745 97.38 0.0 X-RAY
 2005-05-31 ASN A:270 X:270 135.0 0.844 T 61.3 26.0 135.0 0.844 0.0 HOH
 2.653
 OD1
 O
1jxj 1 P04745 97.38 0.0 X-RAY
 2001-09-14 ASN A:270 A:270 155.0 0.969 T 56.9 29.7 155.0 0.969 0.0 HOH
 2.724
 ND2
 O
1nm9 1 P04745 97.38 0.0 X-RAY
 2004-01-20 ASN A:270 A:270 147.0 0.919 T 55.6 28.8 147.0 0.919 0.0 GLC
AGL
GLC
HOH
 6.015
7.338
6.666
3.572
 O
OD1
O
N
 O2
O2
O6
O
3blk 1 P04745 97.38 0.0 X-RAY
 2008-11-25 ASN A:270 A:270 146.0 0.912 T 64.0 28.7 146.0 0.912 0.0 HOH
 2.773
 OD1
 O
3blp 1 P04745 97.38 0.0 X-RAY
 2008-11-18 ASN A:270 X:270 149.0 0.931 T 59.7 28.4 149.0 0.931 0.0 HOH
 2.675
 OD1
 O
1jxk 1 P04745 96.57 0.0 X-RAY
 2001-09-14 ASN A:270 A:270 150.0 0.938 T 54.2 30.0 150.0 0.938 0.0 HOH
 2.689
 ND2
 O
1mfu 1 P04745 96.57 0.0 X-RAY
 2002-11-20 ASN A:270 A:270 153.0 0.956 T 55.8 30.7 153.0 0.956 0.0 GLC
GLC
AGL
HOH
 7.326
6.177
7.659
2.581
 O
O
OD1
ND2
 O6
O2
O2
O
3dhp 1 P04745 96.37 0.0 X-RAY
 2008-07-01 ASN A:270 A:270 147.0 0.919 T 58.6 31.3 147.0 0.919 0.0 HOH
 2.653
 OD1
 O
1kxq 1 P00690 87.1 0.0 X-RAY
 2002-06-19 SER A:270 A:270 115.0 1.0 T 46.4 43.3 115.0 1.0 0.0 HOH
 2.626
 O
 O
SER B:270 B:270 117.0 1.0 T 47.3 44.4 NA NA NA
SER C:270 C:270 116.0 1.0 T 43.0 45.6 NA NA NA
SER D:270 D:270 117.0 1.0 T 44.9 47.8 NA NA NA
1kxt 1 P00690 87.1 0.0 X-RAY
 2002-06-19 SER A:270 A:270 122.0 1.0 T 51.9 28.7 0.0 0.0 1.0 B:None:1.0
 HOH
 3.244
 N
 O
SER C:270 C:270 128.0 1.0 T 48.4 26.4 NA NA NA
SER E:270 E:270 122.0 1.0 G 47.1 34.2 NA NA NA
1kxv 1 P00690 87.1 0.0 X-RAY
 2002-06-19 SER A:270 A:270 113.0 0.983 T 49.4 38.0 113.0 0.983 0.0 HOH
 2.918
 N
 O
SER B:270 B:270 115.0 1.0 T 54.3 30.5 NA NA NA
1dhk 1 P00690 87.1 0.0 X-RAY
 1997-12-24 SER A:270 A:270 112.0 0.974 T 54.8 34.3 65.0 0.565 0.409 B:P02873:0.409
 NAG
NAG
HOH
 7.681
6.841
1.915
 CA
O
H
 HN2
O7
O
1ppi 1 P00690 87.1 0.0 X-RAY
 1995-05-24 SER A:270 A:270 110.0 0.957 T 55.0 31.7 110.0 0.957 0.0 HOH
 2.865
 N
 O
3l2l 1 P00690 86.9 0.0 X-RAY
 2010-04-14 SER A:270 A:270 111.0 0.965 T 53.4 35.7 111.0 0.965 0.0 HOH
 2.750
 OG
 O
3l2m 1 P00690 86.9 0.0 X-RAY
 2010-04-14 SER A:270 A:270 113.0 0.983 T 57.2 33.1 113.0 0.983 0.0 HOH
 1.890
 H
 O
1ua3 1 P00690 86.9 0.0 X-RAY
 2003-10-14 SER A:270 A:270 114.0 0.991 T 59.3 26.5 114.0 0.991 0.0 GLC
GLC
GLC
EDO
HOH
 6.550
6.129
9.430
6.658
2.625
 O
O
CB
N
O
 O3
O2
O2
O1
O
1vah 1 P00690 86.9 0.0 X-RAY
 2005-04-26 SER A:270 A:270 114.0 0.991 T 60.5 21.8 114.0 0.991 0.0 HOH
 2.966
 N
 O
1jfh 1 P00690 86.9 0.0 X-RAY
 1998-12-02 SER A:270 A:270 110.0 0.957 T 48.9 35.8 110.0 0.957 0.0 HOH
 3.558
 N
 O
1ose 1 P00690 86.69 0.0 X-RAY
 1997-04-01 SER A:270 A:270 114.0 0.991 T 51.1 31.7 114.0 0.991 0.0 BGC
HOH
 5.872
3.000
 O
OG
 O2
O
1hx0 1 P00690 86.69 0.0 X-RAY
 2001-08-08 SER A:270 A:270 115.0 1.0 T 57.8 30.3 115.0 1.0 0.0 GLC
GLC
EDO
HOH
 6.261
9.171
8.716
3.006
 O
O
O
OG
 O2
O2
O2
O
1wo2 1 P00690 86.69 0.0 X-RAY
 2005-03-15 SER A:270 A:270 115.0 1.0 T 54.5 27.9 115.0 1.0 0.0 BGC
GLC
GLC
HOH
 6.590
6.106
9.342
2.846
 O
O
CB
OG
 O3
O2
O2
O
1bvn 1 P00690 86.69 0.0 X-RAY
 1998-09-23 SER A:270 P:270 100.0 0.87 T 39.8 60.4 100.0 0.87 0.0 HOH
 2.635
 O
 O
1pif 1 P00690 86.49 0.0 X-RAY
 1996-12-07 SER A:270 A:270 116.0 1.0 T 56.4 17.1 116.0 1.0 0.0 HOH
 2.431
 O
 O
1pig 1 P00690 86.49 0.0 X-RAY
 1996-12-07 SER A:270 A:270 111.0 0.965 T 54.4 33.1 111.0 0.965 0.0 GLC
BGC
HOH
 6.048
8.954
3.171
 O
O
O
 O2
O2
O
4x0n 1 P00690 86.49 0.0 X-RAY
 2015-11-25 SER A:270 A:270 112.0 0.974 T 58.8 30.7 108.0 0.939 0.035 B:None:0.035
 HOH
 4.643
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p19961-f1 1 P19961 100.0 0.0 ASN A:285 A:285 158.0 0.988 G 52.4 31.1
af-p04746-f1 1 P04746 98.83 0.0 ASN A:285 A:285 156.0 0.975 G 52.6 28.6
af-p0dte7-f1 1 P0DTE7 97.46 0.0 ASN A:285 A:285 161.0 1.0 G 52.5 30.5
af-p0dte8-f1 1 P0DTE8 97.46 0.0 ASN A:285 A:285 161.0 1.0 G 52.5 30.7
af-p0dub6-f1 1 P0DUB6 97.46 0.0 ASN A:285 A:285 161.0 1.0 G 52.3 31.6