Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 104118161 . A C CCDS782.1:NM_020978.4:c.1100aAc>aCc_NP_066188.1:p.367N>T Homo sapiens amylase, alpha 2B (pancreatic) (AMY2B), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3old 1 P04746 98.99 0.0 X-RAY
 2011-04-13 ASN A:352 A:352 115.0 0.719 E -125.7 145.4 115.0 0.719 0.0 MPD
HOH
 8.575
3.032
 ND2
CB
 C5
O
3ole 1 P04746 98.99 0.0 X-RAY
 2011-04-13 ASN A:352 A:352 117.0 0.731 E -128.2 143.6 117.0 0.731 0.0 MPD
HOH
 8.573
3.424
 ND2
CA
 C5
O
3olg 1 P04746 98.99 0.0 X-RAY
 2011-04-13 ASN A:352 A:352 113.0 0.706 E -120.9 146.4 113.0 0.706 0.0 BGC
HOH
 9.548
3.717
 ND2
CB
 O6
O
3oli 1 P04746 98.99 0.0 X-RAY
 2011-04-13 ASN A:352 A:352 114.0 0.713 E -114.4 137.1 114.0 0.713 0.0 HOH
 2.884
 ND2
 O
6z8l 1 P04746 98.79 0.0 X-RAY
 2020-12-02 ASN A:352 A:352 112.0 0.7 E -128.1 145.1 112.0 0.7 0.0 HOH
 2.606
 HB3
 O
1b2y 1 P04746 98.79 0.0 X-RAY
 2000-02-16 ASN A:352 A:352 111.0 0.694 E -131.7 133.8 111.0 0.694 0.0 HOH
 3.787
 ND2
 O
1bsi 1 P04746 98.59 0.0 X-RAY
 1999-05-18 ASN A:352 A:352 87.0 0.544 E -111.6 132.0 87.0 0.544 0.0 HOH
 5.376
 OD1
 O
1cpu 1 P04746 98.59 0.0 X-RAY
 1999-06-14 ASN A:352 A:352 86.0 0.537 E -127.9 138.8 86.0 0.537 0.0 HOH
 5.616
 CB
 O
1hny 1 P04746 98.59 0.0 X-RAY
 1996-03-08 ASN A:352 A:352 110.0 0.688 E -133.4 132.6 110.0 0.688 0.0 HOH
 3.312
 OD1
 O
1u2y 1 P04746 98.59 0.0 X-RAY
 2004-09-07 ASN A:352 A:352 113.0 0.706 E -129.9 137.9 113.0 0.706 0.0 HOH
 2.708
 OD1
 O
1u30 1 P04746 98.59 0.0 X-RAY
 2004-09-07 ASN A:352 A:352 121.0 0.756 E -122.3 146.2 121.0 0.756 0.0 HOH
 4.746
 ND2
 O
1u33 1 P04746 98.59 0.0 X-RAY
 2004-09-07 ASN A:352 A:352 119.0 0.744 E -129.8 145.0 119.0 0.744 0.0 HOH
 3.976
 CB
 O
1xcw 1 P04746 98.59 0.0 X-RAY
 2004-12-07 ASN A:352 A:352 116.0 0.725 E -132.8 146.1 116.0 0.725 0.0 HOH
 3.006
 OD1
 O
1xcx 1 P04746 98.59 0.0 X-RAY
 2004-12-07 ASN A:352 A:352 110.0 0.688 E -127.6 139.5 110.0 0.688 0.0 HOH
 2.796
 OD1
 O
1xd0 1 P04746 98.59 0.0 X-RAY
 2004-12-07 ASN A:352 A:352 83.0 0.519 E -120.1 146.2 83.0 0.519 0.0 HOH
 6.330
 C
 O
1xd1 1 P04746 98.59 0.0 X-RAY
 2004-12-07 ASN A:352 A:352 105.0 0.656 E -132.3 135.4 105.0 0.656 0.0 6SA
HOH
 9.421
6.588
 ND2
C
 OW1
O
2qmk 1 P04746 98.59 0.0 X-RAY
 2008-03-25 ASN A:352 A:352 89.0 0.556 E -107.3 155.0 89.0 0.556 0.0 HOH
 4.863
 N
 O
2qv4 1 P04746 98.59 0.0 X-RAY
 2008-03-25 ASN A:352 A:352 87.0 0.544 E -113.4 147.9 87.0 0.544 0.0 HOH
 2.863
 OD1
 O
3bai 1 P04746 98.59 0.0 X-RAY
 2008-03-25 ASN A:352 A:352 114.0 0.713 E -131.9 134.9 114.0 0.713 0.0 HOH
 2.929
 OD1
 O
3baj 1 P04746 98.59 0.0 X-RAY
 2008-03-25 ASN A:352 A:352 87.0 0.544 E -119.8 136.4 87.0 0.544 0.0 HOH
 2.852
 ND2
 O
3baw 1 P04746 98.59 0.0 X-RAY
 2008-03-25 ASN A:352 A:352 88.0 0.55 E -114.1 141.8 88.0 0.55 0.0 HOH
 3.051
 OD1
 O
3ij7 1 P04746 98.59 0.0 X-RAY
 2009-10-27 ASN A:352 A:352 83.0 0.519 E -122.7 137.7 83.0 0.519 0.0 HOH
 4.455
 N
 O
3ij8 1 P04746 98.59 0.0 X-RAY
 2009-10-27 ASN A:352 A:352 79.0 0.494 E -130.2 137.1 79.0 0.494 0.0 HOH
 2.759
 ND2
 O
3ij9 1 P04746 98.59 0.0 X-RAY
 2009-10-27 ASN A:352 A:352 85.0 0.531 E -118.6 138.7 85.0 0.531 0.0 HOH
 3.686
 CA
 O
4gqq 1 P04746 98.59 0.0 X-RAY
 2012-10-24 ASN A:352 A:352 130.0 0.812 S -121.7 -82.5 130.0 0.812 0.0
4gqr 1 P04746 98.59 0.0 X-RAY
 2012-10-24 ASN A:352 A:352 93.0 0.581 E -134.0 142.0 93.0 0.581 0.0 HOH
 2.780
 OD1
 O
4w93 1 P04746 98.59 0.0 X-RAY
 2015-07-15 ASN A:352 A:352 105.0 0.656 E -124.3 138.4 105.0 0.656 0.0 3L9
HOH
 8.514
3.551
 OD1
OD1
 O6E
O
4x9y 1 P04746 98.59 0.0 X-RAY
 2014-12-31 ASN A:352 A:352 80.0 0.5 E -134.6 143.1 80.0 0.5 0.0 HOH
 2.029
 HD22
 O
5e0f 1 P04746 98.59 0.0 X-RAY
 2016-09-07 ASN A:352 A:352 110.0 0.688 E -93.8 134.6 110.0 0.688 0.0 5J7
HOH
 8.593
2.697
 HD21
HB3
 H322
O
5emy 1 P04746 98.59 0.0 X-RAY
 2016-07-06 ASN A:352 A:352 117.0 0.731 E -135.7 141.2 117.0 0.731 0.0 HOH
 2.434
 HD21
 O
5kez 1 P04746 98.59 0.0 X-RAY
 2017-03-29 ASN A:352 A:352 62.0 0.388 E -127.8 141.3 55.0 0.344 0.044 B:None:0.044
 HOH
 2.787
 OD1
 O
5u3a 1 P04746 98.59 0.0 X-RAY
 2017-12-06 ASN A:352 A:352 76.0 0.475 E -134.9 141.3 76.0 0.475 0.0 HOH
 2.733
 HA
 O
5va9 1 P04746 98.59 0.0 X-RAY
 2018-03-28 ASN A:352 A:352 74.0 0.463 E -115.9 127.2 31.0 0.194 0.269 C:None:0.269
 HOH
 6.330
 C
 O
ASN B:352 B:352 76.0 0.475 E -114.4 122.8 NA NA NA
6obx 1 P04746 98.59 0.0 X-RAY
 2020-02-12 ASN A:352 A:352 92.0 0.575 E -137.3 142.0 92.0 0.575 0.0 ZXU
HOH
 9.892
2.443
 HB3
HB2
 OXT
O
6ocn 1 P04746 98.59 0.0 X-RAY
 2020-02-12 ASN A:352 A:352 88.0 0.55 E -131.8 142.7 88.0 0.55 0.0 ZXY
HOH
 9.457
2.744
 HB3
HB2
 O
O
1xgz 1 P04746 98.39 0.0 X-RAY
 2005-05-24 ASN A:352 A:352 116.0 0.725 E -125.2 144.4 116.0 0.725 0.0 HOH
 2.854
 OD1
 O
1xh0 1 P04746 98.39 0.0 X-RAY
 2005-05-24 ASN A:352 A:352 117.0 0.731 E -123.2 150.4 117.0 0.731 0.0 AAO
HOH
 9.127
3.252
 ND2
ND2
 O6T
O
1xh1 1 P04746 98.39 0.0 X-RAY
 2005-05-24 ASN A:352 A:352 90.0 0.562 E -116.2 146.1 90.0 0.562 0.0 HOH
 2.883
 ND2
 O
1xh2 1 P04746 98.39 0.0 X-RAY
 2005-05-24 ASN A:352 A:352 87.0 0.544 E -119.1 142.5 87.0 0.544 0.0 HOH
 2.845
 ND2
 O
3bak 1 P04746 98.39 0.0 X-RAY
 2008-03-25 ASN A:352 A:352 86.0 0.537 E -113.6 141.1 86.0 0.537 0.0 HOH
 2.676
 ND2
 O
3bax 1 P04746 98.39 0.0 X-RAY
 2008-03-25 ASN A:352 A:352 117.0 0.731 E -134.7 136.8 117.0 0.731 0.0 HOH
 2.604
 ND2
 O
3bay 1 P04746 98.39 0.0 X-RAY
 2008-03-25 ASN A:352 A:352 89.0 0.556 E -92.0 157.6 89.0 0.556 0.0 HOH
 4.535
 OD1
 O
1kgw 1 P04746 98.39 0.0 X-RAY
 2002-01-16 ASN A:352 A:352 80.0 0.5 S -152.3 124.8 80.0 0.5 0.0 HOH
 3.666
 ND2
 O
2cpu 1 P04746 98.39 0.0 X-RAY
 2001-06-30 ASN A:352 A:352 81.0 0.506 E -117.9 137.3 81.0 0.506 0.0 HOH
 4.960
 C
 O
3cpu 1 P04746 98.39 0.0 X-RAY
 2001-06-30 ASN A:352 A:352 85.0 0.531 S -123.5 137.6 85.0 0.531 0.0 HOH
 3.047
 ND2
 O
5td4 1 P04746 98.39 0.0 X-RAY
 2016-11-02 ASN A:352 A:352 116.0 0.725 E -109.4 132.0 116.0 0.725 0.0 GLC
HOH
 8.058
5.808
 O
CB
 O3
O
1kgx 1 P04746 98.39 0.0 X-RAY
 2002-01-16 ASN A:352 A:352 70.0 0.438 S -127.1 137.1 70.0 0.438 0.0 HOH
 3.405
 CB
 O
1kbb 1 P04746 98.39 0.0 X-RAY
 2002-04-10 ASN A:352 A:352 114.0 0.713 E -105.3 141.3 114.0 0.713 0.0 HOH
 6.561
 C
 O
1kgu 1 P04746 98.39 0.0 X-RAY
 2002-01-16 ASN A:352 A:352 64.0 0.4 -137.9 128.5 64.0 0.4 0.0 HOH
 5.916
 O
 O
1kb3 1 P04746 98.39 0.0 X-RAY
 2002-05-01 ASN A:352 A:352 71.0 0.444 S -129.2 137.5 71.0 0.444 0.0 HOH
 6.415
 C
 O
1kbk 1 P04746 98.39 0.0 X-RAY
 2002-04-10 ASN A:352 A:352 81.0 0.506 -131.5 134.1 81.0 0.506 0.0 HOH
 6.411
 C
 O
1c8q 1 P04745 97.58 0.0 X-RAY
 2001-06-13 LYS A:352 A:352 79.0 0.395 -141.9 102.6 79.0 0.395 0.0 HOH
 4.317
 NZ
 O
1mfv 1 P04745 97.58 0.0 X-RAY
 2002-11-20 LYS A:352 A:352 105.0 0.525 E -124.5 140.0 105.0 0.525 0.0 GLC
AGL
HOH
 8.398
8.529
2.787
 NZ
NZ
NZ
 O3
O2
O
1smd 1 P04745 97.58 0.0 X-RAY
 1996-07-11 LYS A:352 A:352 109.0 0.545 S -109.3 144.8 109.0 0.545 0.0 HOH
 3.998
 NZ
 O
1xv8 1 P04745 97.58 0.0 X-RAY
 2005-10-11 LYS A:352 A:352 97.0 0.485 E -120.4 164.4 77.0 0.385 0.1 B:P04745:0.1
 HOH
 8.590
 N
 O
LYS B:352 B:352 98.0 0.49 E -120.4 164.5 81.0 0.405 0.085 A:P04745:0.085
 HOH
 9.342
 N
 O
1q4n 1 P04745 97.38 0.0 X-RAY
 2004-03-16 LYS A:352 X:352 110.0 0.55 E -100.0 138.5 110.0 0.55 0.0 HOH
 3.134
 CE
 O
1z32 1 P04745 97.38 0.0 X-RAY
 2005-05-31 LYS A:352 X:352 109.0 0.545 E -118.4 150.6 109.0 0.545 0.0 GLC
HOH
 7.925
4.291
 NZ
NZ
 O3
O
1jxj 1 P04745 97.38 0.0 X-RAY
 2001-09-14 LYS A:352 A:352 98.0 0.49 E -108.1 144.9 98.0 0.49 0.0 HOH
 4.800
 NZ
 O
1nm9 1 P04745 97.38 0.0 X-RAY
 2004-01-20 LYS A:352 A:352 108.0 0.54 E -114.9 130.6 108.0 0.54 0.0 HOH
 4.830
 NZ
 O
3blk 1 P04745 97.38 0.0 X-RAY
 2008-11-25 LYS A:352 A:352 102.0 0.51 S -140.7 146.2 102.0 0.51 0.0 GLC
AGL
HOH
 8.231
8.090
5.248
 NZ
NZ
NZ
 O3
O2
O
3blp 1 P04745 97.38 0.0 X-RAY
 2008-11-18 LYS A:352 X:352 111.0 0.555 E -108.8 144.2 111.0 0.555 0.0 GLC
AGL
HOH
 8.002
7.749
3.483
 NZ
NZ
CG
 O3
O2
O
1jxk 1 P04745 96.57 0.0 X-RAY
 2001-09-14 LYS A:347 A:347 91.0 0.455 -150.4 104.8 91.0 0.455 0.0 HOH
 3.987
 CE
 O
1mfu 1 P04745 96.57 0.0 X-RAY
 2002-11-20 LYS A:347 A:347 107.0 0.535 E -122.3 141.8 107.0 0.535 0.0 GLC
AGL
HOH
 8.200
7.828
2.938
 NZ
NZ
NZ
 O3
O2
O
3dhp 1 P04745 96.37 0.0 X-RAY
 2008-07-01 LYS A:352 A:352 155.0 0.775 E -131.4 151.1 155.0 0.775 0.0 GLC
HOH
 9.923
4.426
 NZ
N
 C6
O
1kxq 1 P00690 87.1 0.0 X-RAY
 2002-06-19 GLU A:352 A:352 77.0 0.405 E -106.9 135.7 14.0 0.074 0.331 H:None:0.332
 HOH
 3.060
 OE1
 O
GLU B:352 B:352 96.0 0.505 E -105.9 134.8 NA NA NA
GLU C:352 C:352 60.0 0.316 E -103.4 132.0 NA NA NA
GLU D:352 D:352 100.0 0.526 E -107.1 132.4 NA NA NA
1kxt 1 P00690 87.1 0.0 X-RAY
 2002-06-19 GLU A:352 A:352 100.0 0.526 E -135.0 130.8 100.0 0.526 0.0 HOH
 2.643
 CG
 O
GLU C:352 C:352 102.0 0.537 E -90.9 138.2 NA NA NA
GLU E:352 E:352 97.0 0.511 E -129.9 128.3 NA NA NA
1kxv 1 P00690 87.1 0.0 X-RAY
 2002-06-19 GLU A:352 A:352 101.0 0.532 E -115.9 142.4 101.0 0.532 0.0 HOH
 4.202
 OE1
 O
GLU B:352 B:352 75.0 0.395 E -108.2 135.8 NA NA NA
1dhk 1 P00690 87.1 0.0 X-RAY
 1997-12-24 GLU A:352 A:352 141.0 0.742 E -136.9 138.0 16.0 0.084 0.658 B:P02873:0.658
 HOH
 3.918
 C
 H2
1ppi 1 P00690 87.1 0.0 X-RAY
 1995-05-24 GLU A:352 A:352 114.0 0.6 E -127.4 145.0 114.0 0.6 0.0 HOH
 3.788
 CA
 O
3l2l 1 P00690 86.9 0.0 X-RAY
 2010-04-14 GLN A:352 A:352 90.0 0.5 -132.4 125.3 90.0 0.5 0.0 GLC
GLC
GLC
HOH
 9.077
8.346
9.362
2.344
 HE22
HE22
HE22
HG3
 O3
HO3
HO2
O
3l2m 1 P00690 86.9 0.0 X-RAY
 2010-04-14 GLN A:352 A:352 87.0 0.483 -128.8 125.4 87.0 0.483 0.0 GLC
GLC
GLC
GLC
GLC
GLC
HOH
 7.845
9.167
8.604
7.304
6.617
7.032
2.349
 HE22
HE22
HE22
HE21
HE21
HE21
OE1
 HO2
HO2
HO3
HO3
HO3
HO2
O
1ua3 1 P00690 86.9 0.0 X-RAY
 2003-10-14 GLU A:352 A:352 66.0 0.347 E -115.4 134.2 66.0 0.347 0.0 GLC
GLC
HOH
 8.881
9.441
3.259
 OE2
OE2
OE2
 O3
O2
O
1vah 1 P00690 86.9 0.0 X-RAY
 2005-04-26 GLU A:352 A:352 98.0 0.516 E -120.5 140.4 98.0 0.516 0.0 HOH
 3.096
 CB
 O
1jfh 1 P00690 86.9 0.0 X-RAY
 1998-12-02 GLU A:352 A:352 117.0 0.616 E -139.1 138.9 117.0 0.616 0.0 HOH
 4.259
 CB
 O
1ose 1 P00690 86.69 0.0 X-RAY
 1997-04-01 GLU A:352 A:352 95.0 0.5 E -130.7 130.9 95.0 0.5 0.0 GLC
HOH
 9.951
3.275
 OE2
OE2
 O3
O
1hx0 1 P00690 86.69 0.0 X-RAY
 2001-08-08 GLU A:352 A:352 96.0 0.505 E -103.4 130.0 96.0 0.505 0.0 BGC
GLC
AC1
EDO
HOH
 9.685
9.310
9.248
7.923
2.936
 OE2
OE1
OE1
CA
OE2
 O6
O3
O2
O2
O
1wo2 1 P00690 86.69 0.0 X-RAY
 2005-03-15 GLU A:352 A:352 95.0 0.5 E -130.6 137.2 95.0 0.5 0.0 GLC
GLC
HOH
 9.376
9.815
2.911
 OE2
OE2
OE2
 O3
O2
O
1bvn 1 P00690 86.69 0.0 X-RAY
 1998-09-23 GLU A:352 P:352 90.0 0.474 E -104.6 132.6 45.0 0.237 0.237 B:P01092:0.237
 HOH
 2.953
 OE2
 O
1pif 1 P00690 86.49 0.0 X-RAY
 1996-12-07 GLU A:352 A:352 79.0 0.416 S -133.1 124.4 79.0 0.416 0.0 HOH
 6.517
 C
 O
1pig 1 P00690 86.49 0.0 X-RAY
 1996-12-07 GLU A:352 A:352 96.0 0.505 S -129.7 135.9 96.0 0.505 0.0 HOH
 6.169
 OE2
 O
4x0n 1 P00690 86.49 0.0 X-RAY
 2015-11-25 GLU A:352 A:352 74.0 0.389 E -105.1 129.6 61.0 0.321 0.068 B:None:0.068
 GOL
HOH
 5.293
4.794
 OE2
OE1
 O2
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p19961-f1 1 P19961 100.0 0.0 ASN A:367 A:367 111.0 0.694 E -113.1 141.6
af-p04746-f1 1 P04746 98.83 0.0 ASN A:367 A:367 115.0 0.719 E -105.7 141.0
af-p0dte7-f1 1 P0DTE7 97.46 0.0 LYS A:367 A:367 122.0 0.61 E -109.0 136.6
af-p0dte8-f1 1 P0DTE8 97.46 0.0 LYS A:367 A:367 120.0 0.6 E -108.9 136.1
af-p0dub6-f1 1 P0DUB6 97.46 0.0 LYS A:367 A:367 122.0 0.61 E -112.3 137.3