Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 104160174 . G A CCDS783.1:NM_000699.2:c.112Gat>Aat_NP_000690.1:p.38D>N Homo sapiens amylase, alpha 2A (pancreatic) (AMY2A), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1b2y 1 P04746 100.0 0.0 X-RAY
 2000-02-16 ASP A:23 A:23 4.0 0.027 H -77.1 -30.4 4.0 0.027 0.0 HOH
 2.703
 OD2
 O
1bsi 1 P04746 99.8 0.0 X-RAY
 1999-05-18 ASP A:23 A:23 6.0 0.04 H -75.2 -36.5 6.0 0.04 0.0 HOH
 2.696
 OD2
 O
1cpu 1 P04746 99.8 0.0 X-RAY
 1999-06-14 ASP A:23 A:23 10.0 0.067 H -71.2 -37.7 10.0 0.067 0.0 HOH
 2.653
 OD2
 O
1hny 1 P04746 99.8 0.0 X-RAY
 1996-03-08 ASP A:23 A:23 3.0 0.02 H -71.7 -34.5 3.0 0.02 0.0 HOH
 2.637
 OD1
 O
1u2y 1 P04746 99.8 0.0 X-RAY
 2004-09-07 ASP A:23 A:23 6.0 0.04 H -71.0 -36.9 6.0 0.04 0.0 HOH
 2.607
 OD2
 O
1u30 1 P04746 99.8 0.0 X-RAY
 2004-09-07 ASP A:23 A:23 7.0 0.047 H -78.6 -35.3 7.0 0.047 0.0 HOH
 2.657
 OD2
 O
1u33 1 P04746 99.8 0.0 X-RAY
 2004-09-07 ASP A:23 A:23 8.0 0.053 H -71.9 -38.8 8.0 0.053 0.0 HOH
 2.563
 OD2
 O
1xcw 1 P04746 99.8 0.0 X-RAY
 2004-12-07 ASP A:23 A:23 8.0 0.053 H -73.6 -36.7 8.0 0.053 0.0 HOH
 2.565
 OD1
 O
1xcx 1 P04746 99.8 0.0 X-RAY
 2004-12-07 ASP A:23 A:23 7.0 0.047 H -70.7 -36.0 7.0 0.047 0.0 HOH
 2.514
 OD1
 O
1xd0 1 P04746 99.8 0.0 X-RAY
 2004-12-07 ASP A:23 A:23 9.0 0.06 H -71.6 -38.5 9.0 0.06 0.0 HOH
 2.601
 OD2
 O
1xd1 1 P04746 99.8 0.0 X-RAY
 2004-12-07 ASP A:23 A:23 6.0 0.04 H -74.8 -39.6 6.0 0.04 0.0 HOH
 2.694
 OD2
 O
2qmk 1 P04746 99.8 0.0 X-RAY
 2008-03-25 ASP A:23 A:23 5.0 0.033 H -65.9 -42.8 5.0 0.033 0.0 HOH
 2.531
 OD1
 O
2qv4 1 P04746 99.8 0.0 X-RAY
 2008-03-25 ASP A:23 A:23 0.0 0.0 H -72.0 -38.7 0.0 0.0 0.0 HOH
 2.614
 OD2
 O
3bai 1 P04746 99.8 0.0 X-RAY
 2008-03-25 ASP A:23 A:23 8.0 0.053 H -70.4 -33.5 8.0 0.053 0.0 HOH
 2.636
 OD2
 O
3baj 1 P04746 99.8 0.0 X-RAY
 2008-03-25 ASP A:23 A:23 1.0 0.007 H -71.5 -32.8 1.0 0.007 0.0 HOH
 2.552
 OD2
 O
3baw 1 P04746 99.8 0.0 X-RAY
 2008-03-25 ASP A:23 A:23 3.0 0.02 H -69.4 -38.3 3.0 0.02 0.0 HOH
 2.568
 OD2
 O
3ij7 1 P04746 99.8 0.0 X-RAY
 2009-10-27 ASP A:23 A:23 1.0 0.007 H -71.1 -38.3 1.0 0.007 0.0 HOH
 2.619
 OD2
 O
3ij8 1 P04746 99.8 0.0 X-RAY
 2009-10-27 ASP A:23 A:23 7.0 0.047 H -74.1 -36.5 7.0 0.047 0.0 HOH
 2.602
 OD1
 O
3ij9 1 P04746 99.8 0.0 X-RAY
 2009-10-27 ASP A:23 A:23 6.0 0.04 H -69.2 -37.8 6.0 0.04 0.0 HOH
 2.561
 OD2
 O
4gqq 1 P04746 99.8 0.0 X-RAY
 2012-10-24 ASP A:23 A:23 6.0 0.04 H -70.4 -30.4 6.0 0.04 0.0 0XR
0XR
HOH
 2.618
6.485
2.717
 OD1
N
OD1
 O3
O1'
O
4gqr 1 P04746 99.8 0.0 X-RAY
 2012-10-24 ASP A:23 A:23 3.0 0.02 H -72.6 -36.0 3.0 0.02 0.0 HOH
 2.632
 OD1
 O
4w93 1 P04746 99.8 0.0 X-RAY
 2015-07-15 ASP A:23 A:23 5.0 0.033 H -74.6 -35.5 5.0 0.033 0.0 HOH
 2.535
 OD1
 O
4x9y 1 P04746 99.8 0.0 X-RAY
 2014-12-31 ASP A:23 A:23 3.0 0.02 H -71.1 -38.9 3.0 0.02 0.0 HOH
 2.682
 OD1
 O
5e0f 1 P04746 99.8 0.0 X-RAY
 2016-09-07 ASP A:23 A:23 5.0 0.033 H -74.3 -35.5 5.0 0.033 0.0 HOH
 2.695
 OD1
 O
5emy 1 P04746 99.8 0.0 X-RAY
 2016-07-06 ASP A:23 A:23 7.0 0.047 H -68.6 -38.2 7.0 0.047 0.0 HOH
 2.625
 OD1
 O
5kez 1 P04746 99.8 0.0 X-RAY
 2017-03-29 ASP A:23 A:23 5.0 0.033 H -74.8 -34.1 5.0 0.033 0.0 HOH
 2.600
 OD2
 O
5u3a 1 P04746 99.8 0.0 X-RAY
 2017-12-06 ASP A:23 A:23 7.0 0.047 H -71.1 -37.9 7.0 0.047 0.0 HOH
 2.575
 OD1
 O
5va9 1 P04746 99.8 0.0 X-RAY
 2018-03-28 ASP A:23 A:23 17.0 0.113 H -63.5 -39.7 17.0 0.113 0.0 HOH
 9.686
 CB
 O
ASP B:23 B:23 4.0 0.027 H -63.3 -40.2 NA NA NA
6obx 1 P04746 99.8 0.0 X-RAY
 2020-02-12 ASP A:23 A:23 6.0 0.04 H -71.2 -38.2 6.0 0.04 0.0 HOH
 2.607
 OD1
 O
6ocn 1 P04746 99.8 0.0 X-RAY
 2020-02-12 ASP A:23 A:23 6.0 0.04 H -72.1 -37.6 6.0 0.04 0.0 HOH
 2.626
 OD1
 O
3old 1 P04746 99.8 0.0 X-RAY
 2011-04-13 ASP A:23 A:23 2.0 0.013 H -72.9 -35.7 2.0 0.013 0.0 HOH
 2.546
 OD1
 O
3ole 1 P04746 99.8 0.0 X-RAY
 2011-04-13 ASP A:23 A:23 3.0 0.02 H -72.4 -37.3 3.0 0.02 0.0 HOH
 2.618
 OD2
 O
3olg 1 P04746 99.8 0.0 X-RAY
 2011-04-13 ASP A:23 A:23 3.0 0.02 H -70.5 -38.4 3.0 0.02 0.0 HOH
 2.685
 OD2
 O
3oli 1 P04746 99.8 0.0 X-RAY
 2011-04-13 ASP A:23 A:23 5.0 0.033 H -72.3 -36.3 5.0 0.033 0.0 HOH
 2.568
 OD2
 O
1kgw 1 P04746 99.6 0.0 X-RAY
 2002-01-16 ASP A:23 A:23 8.0 0.053 H -73.6 -35.6 8.0 0.053 0.0 HOH
 2.909
 OD1
 O
1xgz 1 P04746 99.6 0.0 X-RAY
 2005-05-24 ASP A:23 A:23 3.0 0.02 H -72.7 -35.9 3.0 0.02 0.0 HOH
 2.556
 OD1
 O
1xh0 1 P04746 99.6 0.0 X-RAY
 2005-05-24 ASP A:23 A:23 7.0 0.047 H -70.8 -35.9 7.0 0.047 0.0 HOH
 2.655
 OD1
 O
1xh1 1 P04746 99.6 0.0 X-RAY
 2005-05-24 ASP A:23 A:23 7.0 0.047 H -71.7 -37.0 7.0 0.047 0.0 HOH
 2.503
 OD2
 O
1xh2 1 P04746 99.6 0.0 X-RAY
 2005-05-24 ASP A:23 A:23 8.0 0.053 H -71.0 -36.5 8.0 0.053 0.0 HOH
 2.465
 OD2
 O
3bak 1 P04746 99.6 0.0 X-RAY
 2008-03-25 ASP A:23 A:23 8.0 0.053 H -69.4 -36.0 8.0 0.053 0.0 HOH
 2.642
 OD1
 O
3bax 1 P04746 99.6 0.0 X-RAY
 2008-03-25 ASP A:23 A:23 2.0 0.013 H -74.9 -37.6 2.0 0.013 0.0 HOH
 2.530
 OD1
 O
3bay 1 P04746 99.6 0.0 X-RAY
 2008-03-25 ASP A:23 A:23 9.0 0.06 H -70.7 -34.7 9.0 0.06 0.0 HOH
 2.803
 OD2
 O
1kgx 1 P04746 99.6 0.0 X-RAY
 2002-01-16 ASP A:23 A:23 7.0 0.047 H -72.6 -37.7 7.0 0.047 0.0 HOH
 4.569
 OD1
 O
6z8l 1 P04746 99.6 0.0 X-RAY
 2020-12-02 ASP A:23 A:23 4.0 0.027 H -73.6 -39.8 4.0 0.027 0.0 HOH
 2.707
 OD2
 O
1kgu 1 P04746 99.6 0.0 X-RAY
 2002-01-16 ASP A:23 A:23 3.0 0.02 H -74.8 -32.2 3.0 0.02 0.0 HOH
 2.758
 OD2
 O
2cpu 1 P04746 99.6 0.0 X-RAY
 2001-06-30 ASP A:23 A:23 7.0 0.047 H -71.1 -38.4 7.0 0.047 0.0 HOH
 2.387
 OD2
 O
3cpu 1 P04746 99.6 0.0 X-RAY
 2001-06-30 ASP A:23 A:23 9.0 0.06 H -75.0 -36.8 9.0 0.06 0.0 HOH
 5.007
 OD1
 O
5td4 1 P04746 99.6 0.0 X-RAY
 2016-11-02 ASP A:23 A:23 4.0 0.027 H -70.3 -41.0 4.0 0.027 0.0 GLC
GLC
HOH
 6.296
9.675
2.717
 OD2
OD2
OD1
 O2
O6
O
1kb3 1 P04746 99.6 0.0 X-RAY
 2002-05-01 ASP A:23 A:23 7.0 0.047 H -71.7 -35.7 7.0 0.047 0.0 HOH
 2.599
 OD2
 O
1kbb 1 P04746 99.6 0.0 X-RAY
 2002-04-10 ASP A:23 A:23 5.0 0.033 H -75.4 -31.9 5.0 0.033 0.0 HOH
 2.705
 OD1
 O
1kbk 1 P04746 99.6 0.0 X-RAY
 2002-04-10 ASP A:23 A:23 8.0 0.053 H -70.9 -38.2 8.0 0.053 0.0 HOH
 2.632
 OD1
 O
1c8q 1 P04745 96.98 0.0 X-RAY
 2001-06-13 ASP A:23 A:23 5.0 0.033 H -70.8 -41.9 5.0 0.033 0.0 HOH
 2.632
 OD2
 O
1mfv 1 P04745 96.98 0.0 X-RAY
 2002-11-20 ASP A:23 A:23 4.0 0.027 H -74.4 -39.1 4.0 0.027 0.0 HOH
 2.674
 OD2
 O
1smd 1 P04745 96.98 0.0 X-RAY
 1996-07-11 ASP A:23 A:23 5.0 0.033 H -72.2 -37.0 5.0 0.033 0.0 HOH
 2.733
 OD2
 O
1xv8 1 P04745 96.98 0.0 X-RAY
 2005-10-11 ASP A:23 A:23 3.0 0.02 H -78.2 -31.7 3.0 0.02 0.0 HOH
 5.631
 N
 O
ASP B:23 B:23 2.0 0.013 H -78.2 -31.8 2.0 0.013 0.0 HOH
 5.631
 N
 O
1z32 1 P04745 96.77 0.0 X-RAY
 2005-05-31 ASP A:23 X:23 3.0 0.02 H -73.5 -40.6 3.0 0.02 0.0 HOH
 2.653
 OD1
 O
1jxj 1 P04745 96.77 0.0 X-RAY
 2001-09-14 ASP A:23 A:23 5.0 0.033 H -73.8 -36.5 5.0 0.033 0.0 HOH
 2.512
 OD2
 O
1q4n 1 P04745 96.77 0.0 X-RAY
 2004-03-16 ASP A:23 X:23 6.0 0.04 H -73.2 -38.2 6.0 0.04 0.0 HOH
 2.546
 OD1
 O
1nm9 1 P04745 96.77 0.0 X-RAY
 2004-01-20 ASP A:23 A:23 3.0 0.02 H -71.4 -42.0 3.0 0.02 0.0 HOH
 2.610
 OD1
 O
3blk 1 P04745 96.77 0.0 X-RAY
 2008-11-25 ASP A:23 A:23 3.0 0.02 H -69.9 -41.7 3.0 0.02 0.0 HOH
 2.695
 OD2
 O
3blp 1 P04745 96.77 0.0 X-RAY
 2008-11-18 ASP A:23 X:23 5.0 0.033 H -72.0 -38.8 5.0 0.033 0.0 HOH
 2.525
 OD2
 O
1jxk 1 P04745 95.97 0.0 X-RAY
 2001-09-14 ASP A:23 A:23 5.0 0.033 H -71.8 -37.6 5.0 0.033 0.0 HOH
 2.640
 OD2
 O
1mfu 1 P04745 95.97 0.0 X-RAY
 2002-11-20 ASP A:23 A:23 4.0 0.027 H -68.8 -41.1 4.0 0.027 0.0 HOH
 2.569
 OD2
 O
3dhp 1 P04745 95.77 0.0 X-RAY
 2008-07-01 ASP A:23 A:23 4.0 0.027 H -73.6 -32.7 4.0 0.027 0.0 HOH
 2.601
 OD1
 O
1kxq 1 P00690 86.9 0.0 X-RAY
 2002-06-19 ASP A:23 A:23 8.0 0.053 H -73.8 -41.5 8.0 0.053 0.0 HOH
 2.516
 OD2
 O
ASP B:23 B:23 4.0 0.027 H -71.7 -36.3 NA NA NA
ASP C:23 C:23 6.0 0.04 H -73.7 -37.3 NA NA NA
ASP D:23 D:23 5.0 0.033 H -75.8 -36.6 NA NA NA
1kxt 1 P00690 86.9 0.0 X-RAY
 2002-06-19 ASP A:23 A:23 5.0 0.033 H -76.7 -38.0 5.0 0.033 0.0 HOH
 2.425
 OD1
 O
ASP C:23 C:23 5.0 0.033 H -62.8 -41.6 NA NA NA
ASP E:23 E:23 8.0 0.053 H -67.5 -38.2 NA NA NA
1kxv 1 P00690 86.9 0.0 X-RAY
 2002-06-19 ASP A:23 A:23 4.0 0.027 H -69.6 -38.6 4.0 0.027 0.0 HOH
 2.620
 OD2
 O
ASP B:23 B:23 3.0 0.02 H -73.2 -35.8 NA NA NA
1dhk 1 P00690 86.9 0.0 X-RAY
 1997-12-24 ASP A:23 A:23 2.0 0.013 H -72.2 -36.4 2.0 0.013 0.0 HOH
 2.416
 OD2
 H1
1ppi 1 P00690 86.9 0.0 X-RAY
 1995-05-24 ASP A:23 A:23 2.0 0.013 H -74.1 -36.0 2.0 0.013 0.0 HOH
 2.637
 OD2
 O
1vah 1 P00690 86.69 0.0 X-RAY
 2005-04-26 ASP A:23 A:23 3.0 0.02 H -72.7 -40.9 3.0 0.02 0.0 HOH
 5.393
 N
 O
3l2l 1 P00690 86.69 0.0 X-RAY
 2010-04-14 ASP A:23 A:23 7.0 0.047 H -64.4 -36.6 7.0 0.047 0.0 HOH
 2.601
 OD1
 O
3l2m 1 P00690 86.69 0.0 X-RAY
 2010-04-14 ASP A:23 A:23 7.0 0.047 H -71.6 -31.9 7.0 0.047 0.0 HOH
 2.563
 OD2
 O
1ua3 1 P00690 86.69 0.0 X-RAY
 2003-10-14 ASP A:23 A:23 4.0 0.027 H -71.5 -39.5 4.0 0.027 0.0 EDO
HOH
 9.048
2.607
 O
OD1
 O2
O
1jfh 1 P00690 86.69 0.0 X-RAY
 1998-12-02 ASP A:23 A:23 5.0 0.033 H -71.3 -36.8 5.0 0.033 0.0 HOH
 2.683
 OD2
 O
1ose 1 P00690 86.49 0.0 X-RAY
 1997-04-01 ASP A:23 A:23 5.0 0.033 H -64.7 -37.6 5.0 0.033 0.0 HOH
 2.620
 OD2
 O
1hx0 1 P00690 86.49 0.0 X-RAY
 2001-08-08 ASP A:23 A:23 4.0 0.027 H -72.2 -37.0 4.0 0.027 0.0 EDO
EDO
HOH
 9.088
7.068
2.696
 O
OD1
OD2
 O2
O2
O
1wo2 1 P00690 86.49 0.0 X-RAY
 2005-03-15 ASP A:23 A:23 4.0 0.027 H -70.9 -35.9 4.0 0.027 0.0 EDO
HOH
 8.988
2.750
 O
OD2
 O2
O
1bvn 1 P00690 86.49 0.0 X-RAY
 1998-09-23 ASP A:23 P:23 2.0 0.013 H -76.4 -38.4 2.0 0.013 0.0 HOH
 2.790
 OD2
 O
1pif 1 P00690 86.29 0.0 X-RAY
 1996-12-07 ASP A:23 A:23 3.0 0.02 H -67.8 -38.5 3.0 0.02 0.0 HOH
 2.717
 OD2
 O
1pig 1 P00690 86.29 0.0 X-RAY
 1996-12-07 ASP A:23 A:23 2.0 0.013 H -68.1 -37.6 2.0 0.013 0.0 HOH
 2.735
 OD2
 O
4x0n 1 P00690 86.29 0.0 X-RAY
 2015-11-25 ASP A:23 A:23 4.0 0.027 H -71.3 -36.5 4.0 0.027 0.0 HOH
 2.824
 OD2
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04746-f1 1 P04746 100.0 0.0 ASP A:38 A:38 7.0 0.047 H -71.1 -40.2
af-p19961-f1 1 P19961 98.83 0.0 ASP A:38 A:38 7.0 0.047 H -71.1 -41.0
af-p0dte7-f1 1 P0DTE7 96.87 0.0 ASP A:38 A:38 6.0 0.04 H -70.2 -41.7
af-p0dte8-f1 1 P0DTE8 96.87 0.0 ASP A:38 A:38 7.0 0.047 H -70.4 -40.9
af-p0dub6-f1 1 P0DUB6 96.87 0.0 ASP A:38 A:38 7.0 0.047 H -72.6 -40.1