Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 104160210 . A C CCDS783.1:NM_000699.2:c.148Aag>Cag_NP_000690.1:p.50K>Q Homo sapiens amylase, alpha 2A (pancreatic) (AMY2A), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1b2y 1 P04746 100.0 0.0 X-RAY
 2000-02-16 LYS A:35 A:35 71.0 0.355 T -95.5 10.0 71.0 0.355 0.0 HOH
 6.148
 NZ
 O
1bsi 1 P04746 99.8 0.0 X-RAY
 1999-05-18 LYS A:35 A:35 63.0 0.315 T -85.0 -0.5 63.0 0.315 0.0 HOH
 4.793
 O
 O
1cpu 1 P04746 99.8 0.0 X-RAY
 1999-06-14 LYS A:35 A:35 69.0 0.345 T -92.1 5.5 69.0 0.345 0.0 HOH
 5.199
 O
 O
1hny 1 P04746 99.8 0.0 X-RAY
 1996-03-08 LYS A:35 A:35 72.0 0.36 T -95.1 10.0 72.0 0.36 0.0 HOH
 2.937
 NZ
 O
1u2y 1 P04746 99.8 0.0 X-RAY
 2004-09-07 LYS A:35 A:35 65.0 0.325 T -85.5 0.6 65.0 0.325 0.0 HOH
 4.655
 O
 O
1u30 1 P04746 99.8 0.0 X-RAY
 2004-09-07 LYS A:35 A:35 69.0 0.345 T -94.2 0.9 69.0 0.345 0.0 HOH
 5.135
 N
 O
1u33 1 P04746 99.8 0.0 X-RAY
 2004-09-07 LYS A:35 A:35 66.0 0.33 T -80.4 4.8 66.0 0.33 0.0 HOH
 3.455
 CE
 O
1xcw 1 P04746 99.8 0.0 X-RAY
 2004-12-07 LYS A:35 A:35 69.0 0.345 T -94.9 6.5 69.0 0.345 0.0 HOH
 4.440
 O
 O
1xcx 1 P04746 99.8 0.0 X-RAY
 2004-12-07 LYS A:35 A:35 65.0 0.325 T -89.2 7.8 65.0 0.325 0.0 HOH
 4.645
 O
 O
1xd0 1 P04746 99.8 0.0 X-RAY
 2004-12-07 LYS A:35 A:35 76.0 0.38 T -90.6 3.5 76.0 0.38 0.0 HOH
 4.974
 O
 O
1xd1 1 P04746 99.8 0.0 X-RAY
 2004-12-07 LYS A:35 A:35 69.0 0.345 T -90.7 8.0 69.0 0.345 0.0 HOH
 4.936
 O
 O
2qmk 1 P04746 99.8 0.0 X-RAY
 2008-03-25 LYS A:35 A:35 57.0 0.285 T -90.7 -1.6 57.0 0.285 0.0 HOH
 5.751
 CE
 O
2qv4 1 P04746 99.8 0.0 X-RAY
 2008-03-25 LYS A:35 A:35 60.0 0.3 H -88.1 -3.8 60.0 0.3 0.0 HOH
 3.434
 CE
 O
3bai 1 P04746 99.8 0.0 X-RAY
 2008-03-25 LYS A:35 A:35 77.0 0.385 T -84.2 1.4 77.0 0.385 0.0 HOH
 2.900
 NZ
 O
3baj 1 P04746 99.8 0.0 X-RAY
 2008-03-25 LYS A:35 A:35 81.0 0.405 H -81.2 -1.9 81.0 0.405 0.0 HOH
 2.660
 NZ
 O
3baw 1 P04746 99.8 0.0 X-RAY
 2008-03-25 LYS A:35 A:35 67.0 0.335 T -88.1 1.6 67.0 0.335 0.0 HOH
 4.496
 O
 O
3ij7 1 P04746 99.8 0.0 X-RAY
 2009-10-27 LYS A:35 A:35 71.0 0.355 T -85.2 1.6 71.0 0.355 0.0 B8D
HOH
 8.791
5.450
 CE
CE
 O6
O
3ij8 1 P04746 99.8 0.0 X-RAY
 2009-10-27 LYS A:35 A:35 57.0 0.285 T -89.3 -0.9 57.0 0.285 0.0 HOH
 3.501
 NZ
 O
3ij9 1 P04746 99.8 0.0 X-RAY
 2009-10-27 LYS A:35 A:35 71.0 0.355 T -89.7 0.7 71.0 0.355 0.0 HOH
 3.604
 C
 O
4gqq 1 P04746 99.8 0.0 X-RAY
 2012-10-24 LYS A:35 A:35 65.0 0.325 T -100.3 10.1 65.0 0.325 0.0 HOH
 2.652
 NZ
 O
4gqr 1 P04746 99.8 0.0 X-RAY
 2012-10-24 LYS A:35 A:35 70.0 0.35 T -88.6 6.5 70.0 0.35 0.0 HOH
 2.839
 NZ
 O
4w93 1 P04746 99.8 0.0 X-RAY
 2015-07-15 LYS A:35 A:35 69.0 0.345 T -94.4 6.6 69.0 0.345 0.0 HOH
 2.903
 NZ
 O
4x9y 1 P04746 99.8 0.0 X-RAY
 2014-12-31 LYS A:35 A:35 71.0 0.355 T -95.8 9.1 71.0 0.355 0.0 HOH
 1.944
 HZ1
 O
5e0f 1 P04746 99.8 0.0 X-RAY
 2016-09-07 LYS A:35 A:35 71.0 0.355 T -94.0 7.7 71.0 0.355 0.0 HOH
 2.101
 HZ3
 O
5emy 1 P04746 99.8 0.0 X-RAY
 2016-07-06 LYS A:35 A:35 72.0 0.36 T -95.2 6.9 72.0 0.36 0.0 HOH
 1.945
 HZ2
 O
5kez 1 P04746 99.8 0.0 X-RAY
 2017-03-29 LYS A:35 A:35 76.0 0.38 T -90.0 4.0 76.0 0.38 0.0 HOH
 4.249
 O
 O
5u3a 1 P04746 99.8 0.0 X-RAY
 2017-12-06 LYS A:35 A:35 70.0 0.35 T -94.1 9.4 70.0 0.35 0.0 HOH
 1.956
 HZ2
 O
5va9 1 P04746 99.8 0.0 X-RAY
 2018-03-28 LYS A:35 A:35 71.0 0.355 T -89.0 2.5 71.0 0.355 0.0 HOH
 5.738
 O
 O
LYS B:35 B:35 71.0 0.355 T -88.6 3.5 NA NA NA
6obx 1 P04746 99.8 0.0 X-RAY
 2020-02-12 LYS A:35 A:35 72.0 0.36 T -94.0 6.9 72.0 0.36 0.0 HOH
 1.954
 HZ2
 O
6ocn 1 P04746 99.8 0.0 X-RAY
 2020-02-12 LYS A:35 A:35 70.0 0.35 T -94.4 8.2 70.0 0.35 0.0 HOH
 2.039
 HZ2
 O
3old 1 P04746 99.8 0.0 X-RAY
 2011-04-13 LYS A:35 A:35 81.0 0.405 T -85.6 3.5 81.0 0.405 0.0 GLC
HOH
 8.770
2.651
 CE
O
 O6
O
3ole 1 P04746 99.8 0.0 X-RAY
 2011-04-13 LYS A:35 A:35 84.0 0.42 T -90.3 7.7 84.0 0.42 0.0 GLC
HOH
 8.685
2.697
 CE
O
 O6
O
3olg 1 P04746 99.8 0.0 X-RAY
 2011-04-13 LYS A:35 A:35 78.0 0.39 T -93.2 7.7 78.0 0.39 0.0 HOH
 2.468
 O
 O
3oli 1 P04746 99.8 0.0 X-RAY
 2011-04-13 LYS A:35 A:35 80.0 0.4 T -91.4 3.6 80.0 0.4 0.0 MPD
HOH
 9.284
2.584
 CE
O
 O2
O
1kgw 1 P04746 99.6 0.0 X-RAY
 2002-01-16 LYS A:35 A:35 65.0 0.325 T -87.8 8.7 65.0 0.325 0.0 HOH
 5.981
 O
 O
1xgz 1 P04746 99.6 0.0 X-RAY
 2005-05-24 LYS A:35 A:35 65.0 0.325 T -88.5 5.9 65.0 0.325 0.0 HOH
 3.032
 NZ
 O
1xh0 1 P04746 99.6 0.0 X-RAY
 2005-05-24 LYS A:35 A:35 75.0 0.375 T -84.6 1.4 75.0 0.375 0.0 HOH
 4.630
 O
 O
1xh1 1 P04746 99.6 0.0 X-RAY
 2005-05-24 LYS A:35 A:35 74.0 0.37 H -87.3 -4.4 74.0 0.37 0.0 HOH
 2.604
 NZ
 O
1xh2 1 P04746 99.6 0.0 X-RAY
 2005-05-24 LYS A:35 A:35 78.0 0.39 T -93.5 2.3 78.0 0.39 0.0 HOH
 2.570
 NZ
 O
3bak 1 P04746 99.6 0.0 X-RAY
 2008-03-25 LYS A:35 A:35 63.0 0.315 T -88.2 2.2 63.0 0.315 0.0 HOH
 3.859
 O
 O
3bax 1 P04746 99.6 0.0 X-RAY
 2008-03-25 LYS A:35 A:35 69.0 0.345 T -89.7 6.0 69.0 0.345 0.0 HOH
 2.734
 NZ
 O
3bay 1 P04746 99.6 0.0 X-RAY
 2008-03-25 LYS A:35 A:35 68.0 0.34 H -79.2 -6.8 68.0 0.34 0.0 HOH
 4.291
 O
 O
1kgx 1 P04746 99.6 0.0 X-RAY
 2002-01-16 LYS A:35 A:35 59.0 0.295 T -88.8 3.5 59.0 0.295 0.0 HOH
 4.730
 O
 O
6z8l 1 P04746 99.6 0.0 X-RAY
 2020-12-02 LYS A:35 A:35 80.0 0.4 T -94.4 5.2 80.0 0.4 0.0 HOH
 1.968
 HZ2
 O
1kgu 1 P04746 99.6 0.0 X-RAY
 2002-01-16 LYS A:35 A:35 71.0 0.355 T -94.8 8.3 71.0 0.355 0.0 HOH
 3.301
 NZ
 O
2cpu 1 P04746 99.6 0.0 X-RAY
 2001-06-30 LYS A:35 A:35 64.0 0.32 T -85.1 1.4 64.0 0.32 0.0 HOH
 4.629
 O
 O
3cpu 1 P04746 99.6 0.0 X-RAY
 2001-06-30 LYS A:35 A:35 64.0 0.32 T -90.9 10.3 64.0 0.32 0.0 HOH
 4.980
 O
 O
5td4 1 P04746 99.6 0.0 X-RAY
 2016-11-02 LYS A:35 A:35 74.0 0.37 T -95.8 15.1 74.0 0.37 0.0 HOH
 5.915
 CE
 O
1kb3 1 P04746 99.6 0.0 X-RAY
 2002-05-01 LYS A:35 A:35 61.0 0.305 T -88.8 5.9 61.0 0.305 0.0 HOH
 3.811
 CE
 O
1kbb 1 P04746 99.6 0.0 X-RAY
 2002-04-10 LYS A:35 A:35 68.0 0.34 T -92.4 5.8 68.0 0.34 0.0 HOH
 5.590
 CE
 O
1kbk 1 P04746 99.6 0.0 X-RAY
 2002-04-10 LYS A:35 A:35 65.0 0.325 T -97.4 2.6 65.0 0.325 0.0 HOH
 4.524
 O
 O
1c8q 1 P04745 96.98 0.0 X-RAY
 2001-06-13 LYS A:35 A:35 78.0 0.39 T -92.3 3.6 78.0 0.39 0.0 HOH
 5.488
 CE
 O
1mfv 1 P04745 96.98 0.0 X-RAY
 2002-11-20 LYS A:35 A:35 77.0 0.385 T -88.9 -0.5 77.0 0.385 0.0 HOH
 2.647
 O
 O
1smd 1 P04745 96.98 0.0 X-RAY
 1996-07-11 LYS A:35 A:35 75.0 0.375 T -99.2 17.0 75.0 0.375 0.0 HOH
 5.747
 CE
 O
1xv8 1 P04745 96.98 0.0 X-RAY
 2005-10-11 LYS A:35 A:35 79.0 0.395 T -96.4 23.1 79.0 0.395 0.0 HOH
 5.119
 N
 O
LYS B:35 B:35 78.0 0.39 T -96.3 23.1 78.0 0.39 0.0 HOH
 5.119
 N
 O
1z32 1 P04745 96.77 0.0 X-RAY
 2005-05-31 LYS A:35 X:35 73.0 0.365 T -92.0 2.2 73.0 0.365 0.0 HOH
 2.656
 O
 O
1jxj 1 P04745 96.77 0.0 X-RAY
 2001-09-14 LYS A:35 A:35 81.0 0.405 T -87.1 12.3 81.0 0.405 0.0 HOH
 2.700
 O
 O
1q4n 1 P04745 96.77 0.0 X-RAY
 2004-03-16 LYS A:35 X:35 74.0 0.37 T -91.8 7.0 74.0 0.37 0.0 HOH
 2.593
 NZ
 O
1nm9 1 P04745 96.77 0.0 X-RAY
 2004-01-20 LYS A:35 A:35 75.0 0.375 T -87.9 3.5 75.0 0.375 0.0 HOH
 2.689
 O
 O
3blk 1 P04745 96.77 0.0 X-RAY
 2008-11-25 LYS A:35 A:35 77.0 0.385 T -88.0 1.5 77.0 0.385 0.0 HOH
 2.744
 O
 O
3blp 1 P04745 96.77 0.0 X-RAY
 2008-11-18 LYS A:35 X:35 78.0 0.39 T -91.4 1.7 78.0 0.39 0.0 HOH
 2.621
 O
 O
1jxk 1 P04745 95.97 0.0 X-RAY
 2001-09-14 LYS A:35 A:35 84.0 0.42 T -89.6 7.4 84.0 0.42 0.0 HOH
 2.696
 O
 O
1mfu 1 P04745 95.97 0.0 X-RAY
 2002-11-20 LYS A:35 A:35 80.0 0.4 T -88.7 8.3 80.0 0.4 0.0 AGL
HMC
HOH
 9.725
6.859
2.792
 CE
NZ
O
 C6
O7
O
3dhp 1 P04745 95.77 0.0 X-RAY
 2008-07-01 LYS A:35 A:35 75.0 0.375 T -93.9 4.7 75.0 0.375 0.0 HOH
 2.602
 NZ
 O
1kxq 1 P00690 86.9 0.0 X-RAY
 2002-06-19 LYS A:35 A:35 79.0 0.395 T -85.2 10.3 79.0 0.395 0.0 HOH
 2.683
 O
 O
LYS B:35 B:35 75.0 0.375 T -86.4 7.9 NA NA NA
LYS C:35 C:35 78.0 0.39 T -88.5 10.4 NA NA NA
LYS D:35 D:35 77.0 0.385 T -85.9 8.7 NA NA NA
1kxt 1 P00690 86.9 0.0 X-RAY
 2002-06-19 LYS A:35 A:35 73.0 0.365 T -91.6 9.6 73.0 0.365 0.0 HOH
 2.617
 O
 O
LYS C:35 C:35 81.0 0.405 T -90.6 13.5 NA NA NA
LYS E:35 E:35 74.0 0.37 T -87.2 6.4 NA NA NA
1kxv 1 P00690 86.9 0.0 X-RAY
 2002-06-19 LYS A:35 A:35 72.0 0.36 T -88.4 7.7 72.0 0.36 0.0 HOH
 2.708
 NZ
 O
LYS B:35 B:35 85.0 0.425 T -94.5 9.9 NA NA NA
1dhk 1 P00690 86.9 0.0 X-RAY
 1997-12-24 LYS A:35 A:35 81.0 0.405 T -82.5 8.0 81.0 0.405 0.0 HOH
 2.525
 O
 H2
1ppi 1 P00690 86.9 0.0 X-RAY
 1995-05-24 LYS A:35 A:35 83.0 0.415 T -88.5 10.6 83.0 0.415 0.0 HOH
 2.767
 O
 O
1vah 1 P00690 86.69 0.0 X-RAY
 2005-04-26 LYS A:35 A:35 73.0 0.365 T -76.0 1.7 73.0 0.365 0.0 HOH
 2.548
 O
 O
3l2l 1 P00690 86.69 0.0 X-RAY
 2010-04-14 LYS A:35 A:35 86.0 0.43 T -93.0 9.7 86.0 0.43 0.0 HOH
 2.150
 HZ3
 O
3l2m 1 P00690 86.69 0.0 X-RAY
 2010-04-14 LYS A:35 A:35 88.0 0.44 T -93.0 9.5 88.0 0.44 0.0 HOH
 2.153
 HZ3
 O
1ua3 1 P00690 86.69 0.0 X-RAY
 2003-10-14 LYS A:35 A:35 86.0 0.43 T -96.5 11.6 86.0 0.43 0.0 GLC
EDO
HOH
 9.325
6.949
2.766
 CE
CE
O
 O6
O1
O
1jfh 1 P00690 86.69 0.0 X-RAY
 1998-12-02 LYS A:35 A:35 80.0 0.4 T -85.9 6.8 80.0 0.4 0.0 GLC
HOH
 8.546
2.647
 CE
O
 O6
O
1ose 1 P00690 86.49 0.0 X-RAY
 1997-04-01 LYS A:35 A:35 76.0 0.38 T -89.4 17.4 76.0 0.38 0.0 HOH
 2.791
 O
 O
1hx0 1 P00690 86.49 0.0 X-RAY
 2001-08-08 LYS A:35 A:35 84.0 0.42 T -92.1 9.6 84.0 0.42 0.0 EDO
HOH
 6.781
2.690
 CE
NZ
 O1
O
1wo2 1 P00690 86.49 0.0 X-RAY
 2005-03-15 LYS A:35 A:35 84.0 0.42 T -89.1 12.8 84.0 0.42 0.0 GLC
EDO
HOH
 9.126
6.902
2.714
 CE
CE
O
 O6
O1
O
1bvn 1 P00690 86.49 0.0 X-RAY
 1998-09-23 LYS A:35 P:35 87.0 0.435 T -85.3 8.0 87.0 0.435 0.0 HOH
 3.287
 O
 O
1pif 1 P00690 86.29 0.0 X-RAY
 1996-12-07 LYS A:35 A:35 75.0 0.375 T -78.6 1.1 75.0 0.375 0.0 HOH
 2.666
 O
 O
1pig 1 P00690 86.29 0.0 X-RAY
 1996-12-07 LYS A:35 A:35 73.0 0.365 T -81.2 1.8 73.0 0.365 0.0 GLC
HOH
 8.949
2.804
 CE
O
 O6
O
4x0n 1 P00690 86.29 0.0 X-RAY
 2015-11-25 LYS A:35 A:35 73.0 0.365 T -91.8 8.9 73.0 0.365 0.0 HOH
 2.816
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04746-f1 1 P04746 100.0 0.0 LYS A:50 A:50 65.0 0.325 T -97.4 4.5
af-p19961-f1 1 P19961 98.83 0.0 LYS A:50 A:50 81.0 0.405 T -96.5 7.4
af-p0dte7-f1 1 P0DTE7 96.87 0.0 LYS A:50 A:50 80.0 0.4 T -96.0 6.6
af-p0dte8-f1 1 P0DTE8 96.87 0.0 LYS A:50 A:50 79.0 0.395 T -95.1 7.1
af-p0dub6-f1 1 P0DUB6 96.87 0.0 LYS A:50 A:50 75.0 0.375 T -95.5 5.8