Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 104160692 . A C CCDS783.1:NM_000699.2:c.285agA>agC_NP_000690.1:p.95R>S Homo sapiens amylase, alpha 2A (pancreatic) (AMY2A), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1b2y 1 P04746 100.0 0.0 X-RAY
 2000-02-16 ARG A:80 A:80 105.0 0.467 H -59.0 -41.6 105.0 0.467 0.0 HOH
 7.218
 NH2
 O
1bsi 1 P04746 99.8 0.0 X-RAY
 1999-05-18 ARG A:80 A:80 98.0 0.436 H -60.7 -45.8 98.0 0.436 0.0 HOH
 3.885
 CB
 O
1cpu 1 P04746 99.8 0.0 X-RAY
 1999-06-14 ARG A:80 A:80 90.0 0.4 H -62.0 -41.1 90.0 0.4 0.0 HOH
 3.172
 NH1
 O
1hny 1 P04746 99.8 0.0 X-RAY
 1996-03-08 ARG A:80 A:80 108.0 0.48 H -58.8 -42.0 108.0 0.48 0.0 HOH
 3.503
 O
 O
1u2y 1 P04746 99.8 0.0 X-RAY
 2004-09-07 ARG A:80 A:80 108.0 0.48 H -60.7 -41.6 108.0 0.48 0.0 HOH
 5.749
 NE
 O
1u30 1 P04746 99.8 0.0 X-RAY
 2004-09-07 ARG A:80 A:80 89.0 0.396 H -62.6 -39.4 89.0 0.396 0.0 HOH
 3.889
 NH2
 O
1u33 1 P04746 99.8 0.0 X-RAY
 2004-09-07 ARG A:80 A:80 95.0 0.422 H -62.8 -35.3 95.0 0.422 0.0 HOH
 3.441
 O
 O
1xcw 1 P04746 99.8 0.0 X-RAY
 2004-12-07 ARG A:80 A:80 93.0 0.413 H -63.5 -40.5 93.0 0.413 0.0 HOH
 3.733
 NH2
 O
1xcx 1 P04746 99.8 0.0 X-RAY
 2004-12-07 ARG A:80 A:80 95.0 0.422 H -62.5 -36.8 95.0 0.422 0.0 HOH
 7.383
 NH1
 O
1xd0 1 P04746 99.8 0.0 X-RAY
 2004-12-07 ARG A:80 A:80 94.0 0.418 H -62.2 -37.1 94.0 0.418 0.0 HOH
 6.257
 C
 O
1xd1 1 P04746 99.8 0.0 X-RAY
 2004-12-07 ARG A:80 A:80 103.0 0.458 H -63.7 -34.9 103.0 0.458 0.0 HOH
 6.160
 C
 O
2qmk 1 P04746 99.8 0.0 X-RAY
 2008-03-25 ARG A:80 A:80 94.0 0.418 H -58.6 -50.8 94.0 0.418 0.0 HOH
 2.914
 NH2
 O
2qv4 1 P04746 99.8 0.0 X-RAY
 2008-03-25 ARG A:80 A:80 110.0 0.489 H -59.1 -45.2 110.0 0.489 0.0 HOH
 2.754
 NH1
 O
3bai 1 P04746 99.8 0.0 X-RAY
 2008-03-25 ARG A:80 A:80 93.0 0.413 H -60.0 -42.7 93.0 0.413 0.0 HOH
 2.619
 NE
 O
3baj 1 P04746 99.8 0.0 X-RAY
 2008-03-25 ARG A:80 A:80 98.0 0.436 H -62.5 -43.2 98.0 0.436 0.0 HOH
 5.873
 C
 O
3baw 1 P04746 99.8 0.0 X-RAY
 2008-03-25 ARG A:80 A:80 94.0 0.418 H -61.3 -44.9 94.0 0.418 0.0 HOH
 2.821
 NH1
 O
3ij7 1 P04746 99.8 0.0 X-RAY
 2009-10-27 ARG A:80 A:80 109.0 0.484 H -61.9 -42.9 109.0 0.484 0.0 HOH
 2.890
 NH1
 O
3ij8 1 P04746 99.8 0.0 X-RAY
 2009-10-27 ARG A:80 A:80 102.0 0.453 H -62.8 -41.5 102.0 0.453 0.0 HOH
 3.124
 NH2
 O
3ij9 1 P04746 99.8 0.0 X-RAY
 2009-10-27 ARG A:80 A:80 105.0 0.467 H -63.3 -40.3 105.0 0.467 0.0 HOH
 2.581
 NH2
 O
4gqq 1 P04746 99.8 0.0 X-RAY
 2012-10-24 ARG A:80 A:80 107.0 0.476 H -62.8 -35.3 107.0 0.476 0.0 0XR
HOH
 6.886
2.693
 C
NH2
 C5
O
4gqr 1 P04746 99.8 0.0 X-RAY
 2012-10-24 ARG A:80 A:80 98.0 0.436 H -59.0 -43.1 98.0 0.436 0.0 HOH
 2.850
 NH1
 O
4w93 1 P04746 99.8 0.0 X-RAY
 2015-07-15 ARG A:80 A:80 104.0 0.462 H -61.1 -41.4 104.0 0.462 0.0 HOH
 2.842
 NH1
 O
4x9y 1 P04746 99.8 0.0 X-RAY
 2014-12-31 ARG A:80 A:80 103.0 0.458 H -61.9 -42.3 103.0 0.458 0.0 HOH
 2.025
 HH11
 O
5e0f 1 P04746 99.8 0.0 X-RAY
 2016-09-07 ARG A:80 A:80 107.0 0.476 H -61.2 -42.4 107.0 0.476 0.0 HOH
 2.088
 HH11
 O
5emy 1 P04746 99.8 0.0 X-RAY
 2016-07-06 ARG A:80 A:80 107.0 0.476 H -60.5 -43.7 107.0 0.476 0.0 HOH
 1.972
 HH11
 O
5kez 1 P04746 99.8 0.0 X-RAY
 2017-03-29 ARG A:80 A:80 102.0 0.453 H -55.3 -46.1 102.0 0.453 0.0 HOH
 2.591
 NH1
 O
5u3a 1 P04746 99.8 0.0 X-RAY
 2017-12-06 ARG A:80 A:80 103.0 0.458 H -61.0 -42.4 103.0 0.458 0.0 HOH
 2.056
 HH11
 O
5va9 1 P04746 99.8 0.0 X-RAY
 2018-03-28 ARG A:80 A:80 102.0 0.453 H -55.1 -41.5 102.0 0.453 0.0 HOH
 8.381
 C
 O
ARG B:80 B:80 110.0 0.489 H -54.7 -42.4 NA NA NA
6obx 1 P04746 99.8 0.0 X-RAY
 2020-02-12 ARG A:80 A:80 104.0 0.462 H -62.3 -42.2 104.0 0.462 0.0 HOH
 1.987
 HH11
 O
6ocn 1 P04746 99.8 0.0 X-RAY
 2020-02-12 ARG A:80 A:80 106.0 0.471 H -62.3 -41.7 106.0 0.471 0.0 HOH
 2.010
 HH11
 O
3old 1 P04746 99.8 0.0 X-RAY
 2011-04-13 ARG A:80 A:80 102.0 0.453 H -62.0 -40.4 102.0 0.453 0.0 HOH
 2.845
 CD
 O
3ole 1 P04746 99.8 0.0 X-RAY
 2011-04-13 ARG A:80 A:80 99.0 0.44 H -60.7 -41.5 99.0 0.44 0.0 HOH
 2.829
 NH1
 O
3olg 1 P04746 99.8 0.0 X-RAY
 2011-04-13 ARG A:80 A:80 107.0 0.476 H -62.9 -38.8 107.0 0.476 0.0 HOH
 2.793
 NH1
 O
3oli 1 P04746 99.8 0.0 X-RAY
 2011-04-13 ARG A:80 A:80 100.0 0.444 H -61.9 -39.8 100.0 0.444 0.0 MPD
HOH
 8.969
2.906
 O
NH1
 C5
O
1kgw 1 P04746 99.6 0.0 X-RAY
 2002-01-16 ARG A:80 A:80 105.0 0.467 H -64.1 -42.3 105.0 0.467 0.0 HOH
 2.924
 CD
 O
1xgz 1 P04746 99.6 0.0 X-RAY
 2005-05-24 ARG A:80 A:80 111.0 0.493 H -60.4 -41.2 111.0 0.493 0.0 HOH
 3.549
 NH1
 O
1xh0 1 P04746 99.6 0.0 X-RAY
 2005-05-24 ARG A:80 A:80 108.0 0.48 H -62.4 -38.9 108.0 0.48 0.0 HOH
 2.938
 NH1
 O
1xh1 1 P04746 99.6 0.0 X-RAY
 2005-05-24 ARG A:80 A:80 86.0 0.382 H -61.5 -38.7 86.0 0.382 0.0 HOH
 2.769
 NE
 O
1xh2 1 P04746 99.6 0.0 X-RAY
 2005-05-24 ARG A:80 A:80 113.0 0.502 H -60.6 -38.5 113.0 0.502 0.0 HOH
 2.863
 NH2
 O
3bak 1 P04746 99.6 0.0 X-RAY
 2008-03-25 ARG A:80 A:80 83.0 0.369 H -61.7 -42.2 83.0 0.369 0.0 HOH
 2.630
 NE
 O
3bax 1 P04746 99.6 0.0 X-RAY
 2008-03-25 ARG A:80 A:80 120.0 0.533 H -67.3 -36.7 120.0 0.533 0.0 HOH
 2.604
 NH1
 O
3bay 1 P04746 99.6 0.0 X-RAY
 2008-03-25 ARG A:80 A:80 80.0 0.356 H -60.9 -50.5 80.0 0.356 0.0 HOH
 2.505
 NE
 O
1kgx 1 P04746 99.6 0.0 X-RAY
 2002-01-16 ARG A:80 A:80 95.0 0.422 H -62.1 -40.7 95.0 0.422 0.0 HOH
 3.218
 NE
 O
6z8l 1 P04746 99.6 0.0 X-RAY
 2020-12-02 ARG A:80 A:80 104.0 0.462 H -60.5 -43.0 104.0 0.462 0.0 HOH
 2.009
 HH11
 O
1kgu 1 P04746 99.6 0.0 X-RAY
 2002-01-16 ARG A:80 A:80 99.0 0.44 H -60.8 -43.3 99.0 0.44 0.0 HOH
 2.680
 NH1
 O
2cpu 1 P04746 99.6 0.0 X-RAY
 2001-06-30 ARG A:80 A:80 104.0 0.462 H -60.1 -43.6 104.0 0.462 0.0 HOH
 6.014
 C
 O
3cpu 1 P04746 99.6 0.0 X-RAY
 2001-06-30 ARG A:80 A:80 96.0 0.427 H -61.5 -40.0 96.0 0.427 0.0 HOH
 3.789
 CB
 O
5td4 1 P04746 99.6 0.0 X-RAY
 2016-11-02 ARG A:80 A:80 102.0 0.453 H -62.1 -45.9 102.0 0.453 0.0 HOH
 2.971
 NH1
 O
1kb3 1 P04746 99.6 0.0 X-RAY
 2002-05-01 ARG A:80 A:80 93.0 0.413 H -63.6 -41.2 93.0 0.413 0.0 HOH
 3.002
 NE
 O
1kbb 1 P04746 99.6 0.0 X-RAY
 2002-04-10 ARG A:80 A:80 101.0 0.449 H -63.6 -40.9 101.0 0.449 0.0 HOH
 5.952
 C
 O
1kbk 1 P04746 99.6 0.0 X-RAY
 2002-04-10 ARG A:80 A:80 102.0 0.453 H -59.9 -43.0 102.0 0.453 0.0 HOH
 5.952
 C
 O
1c8q 1 P04745 96.98 0.0 X-RAY
 2001-06-13 ARG A:80 A:80 105.0 0.467 H -61.7 -43.4 105.0 0.467 0.0 HOH
 3.230
 NH1
 O
1mfv 1 P04745 96.98 0.0 X-RAY
 2002-11-20 ARG A:80 A:80 103.0 0.458 H -60.5 -41.7 103.0 0.458 0.0 HOH
 3.283
 O
 O
1smd 1 P04745 96.98 0.0 X-RAY
 1996-07-11 ARG A:80 A:80 104.0 0.462 H -59.7 -42.2 104.0 0.462 0.0 HOH
 3.153
 NH1
 O
1xv8 1 P04745 96.98 0.0 X-RAY
 2005-10-11 ARG A:80 A:80 100.0 0.444 H -52.7 -50.2 100.0 0.444 0.0 HOH
 3.108
 NH2
 O
ARG B:80 B:80 101.0 0.449 H -52.6 -50.2 101.0 0.449 0.0 HOH
 3.108
 NH2
 O
1z32 1 P04745 96.77 0.0 X-RAY
 2005-05-31 ARG A:80 X:80 103.0 0.458 H -60.5 -42.3 103.0 0.458 0.0 HOH
 2.882
 NH1
 O
1jxj 1 P04745 96.77 0.0 X-RAY
 2001-09-14 ARG A:80 A:80 101.0 0.449 H -59.0 -43.0 101.0 0.449 0.0 HOH
 3.177
 NH1
 O
1q4n 1 P04745 96.77 0.0 X-RAY
 2004-03-16 ARG A:80 X:80 107.0 0.476 H -58.6 -48.5 107.0 0.476 0.0 HOH
 3.081
 NH1
 O
1nm9 1 P04745 96.77 0.0 X-RAY
 2004-01-20 ARG A:80 A:80 106.0 0.471 H -58.8 -43.8 106.0 0.471 0.0 HOH
 2.863
 NH1
 O
3blk 1 P04745 96.77 0.0 X-RAY
 2008-11-25 ARG A:80 A:80 104.0 0.462 H -62.0 -41.0 104.0 0.462 0.0 HOH
 2.690
 NH1
 O
3blp 1 P04745 96.77 0.0 X-RAY
 2008-11-18 ARG A:80 X:80 107.0 0.476 H -57.5 -42.8 107.0 0.476 0.0 HOH
 2.805
 NH1
 O
1jxk 1 P04745 95.97 0.0 X-RAY
 2001-09-14 ARG A:80 A:80 102.0 0.453 H -55.7 -43.3 102.0 0.453 0.0 HOH
 2.832
 NH1
 O
1mfu 1 P04745 95.97 0.0 X-RAY
 2002-11-20 ARG A:80 A:80 107.0 0.476 H -57.7 -44.8 107.0 0.476 0.0 HOH
 2.662
 NH1
 O
3dhp 1 P04745 95.77 0.0 X-RAY
 2008-07-01 ARG A:80 A:80 105.0 0.467 H -59.3 -41.2 105.0 0.467 0.0 HOH
 2.848
 NH1
 O
1kxq 1 P00690 86.9 0.0 X-RAY
 2002-06-19 ARG A:80 A:80 107.0 0.476 H -58.9 -46.8 107.0 0.476 0.0 HOH
 2.760
 NH2
 O
ARG B:80 B:80 109.0 0.484 H -62.6 -44.2 NA NA NA
ARG C:80 C:80 108.0 0.48 H -62.1 -45.2 NA NA NA
ARG D:80 D:80 96.0 0.427 H -60.1 -44.6 NA NA NA
1kxt 1 P00690 86.9 0.0 X-RAY
 2002-06-19 ARG A:80 A:80 100.0 0.444 H -61.6 -46.1 100.0 0.444 0.0 HOH
 2.502
 NH2
 O
ARG C:80 C:80 110.0 0.489 H -64.8 -42.2 NA NA NA
ARG E:80 E:80 106.0 0.471 H -60.5 -49.7 NA NA NA
1kxv 1 P00690 86.9 0.0 X-RAY
 2002-06-19 ARG A:80 A:80 108.0 0.48 H -60.1 -43.3 108.0 0.48 0.0 HOH
 2.936
 NH2
 O
ARG B:80 B:80 112.0 0.498 H -61.7 -40.9 NA NA NA
1dhk 1 P00690 86.9 0.0 X-RAY
 1997-12-24 ARG A:80 A:80 97.0 0.431 H -64.1 -43.8 97.0 0.431 0.0 HOH
 2.935
 O
 H2
1ppi 1 P00690 86.9 0.0 X-RAY
 1995-05-24 ARG A:80 A:80 104.0 0.462 H -65.1 -39.5 104.0 0.462 0.0 HOH
 3.076
 NH1
 O
1vah 1 P00690 86.69 0.0 X-RAY
 2005-04-26 ARG A:80 A:80 105.0 0.467 H -62.9 -36.5 105.0 0.467 0.0 HOH
 7.247
 NH1
 O
3l2l 1 P00690 86.69 0.0 X-RAY
 2010-04-14 ARG A:80 A:80 102.0 0.453 H -59.8 -45.2 102.0 0.453 0.0 HOH
 2.507
 HH11
 O
3l2m 1 P00690 86.69 0.0 X-RAY
 2010-04-14 ARG A:80 A:80 101.0 0.449 H -58.0 -48.0 101.0 0.449 0.0 HOH
 2.048
 HH12
 O
1ua3 1 P00690 86.69 0.0 X-RAY
 2003-10-14 ARG A:80 A:80 99.0 0.44 H -58.3 -46.0 99.0 0.44 0.0 HOH
 2.915
 NH2
 O
1jfh 1 P00690 86.69 0.0 X-RAY
 1998-12-02 ARG A:80 A:80 102.0 0.453 H -62.6 -43.1 102.0 0.453 0.0 HOH
 2.918
 NH1
 O
1ose 1 P00690 86.49 0.0 X-RAY
 1997-04-01 ARG A:80 A:80 102.0 0.453 H -57.6 -39.8 102.0 0.453 0.0 HOH
 3.474
 NH1
 O
1hx0 1 P00690 86.49 0.0 X-RAY
 2001-08-08 ARG A:80 A:80 101.0 0.449 H -59.4 -42.5 101.0 0.449 0.0 HOH
 2.901
 NH2
 O
1wo2 1 P00690 86.49 0.0 X-RAY
 2005-03-15 ARG A:80 A:80 99.0 0.44 H -59.6 -44.1 99.0 0.44 0.0 HOH
 2.827
 NH2
 O
1bvn 1 P00690 86.49 0.0 X-RAY
 1998-09-23 ARG A:80 P:80 106.0 0.471 H -47.8 -38.3 106.0 0.471 0.0 HOH
 4.025
 CB
 O
1pif 1 P00690 86.29 0.0 X-RAY
 1996-12-07 ARG A:80 A:80 100.0 0.444 H -59.1 -41.5 100.0 0.444 0.0 HOH
 4.022
 NH2
 O
1pig 1 P00690 86.29 0.0 X-RAY
 1996-12-07 ARG A:80 A:80 101.0 0.449 H -57.7 -45.8 101.0 0.449 0.0 HOH
 3.659
 CB
 O
4x0n 1 P00690 86.29 0.0 X-RAY
 2015-11-25 ARG A:80 A:80 102.0 0.453 H -59.7 -43.6 102.0 0.453 0.0 HOH
 2.810
 NH1
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04746-f1 1 P04746 100.0 0.0 ARG A:95 A:95 94.0 0.418 H -63.3 -39.3
af-p19961-f1 1 P19961 98.83 0.0 ARG A:95 A:95 86.0 0.382 H -59.7 -42.1
af-p0dte7-f1 1 P0DTE7 96.87 0.0 ARG A:95 A:95 87.0 0.387 H -59.7 -42.1
af-p0dte8-f1 1 P0DTE8 96.87 0.0 ARG A:95 A:95 89.0 0.396 H -59.9 -41.9
af-p0dub6-f1 1 P0DUB6 96.87 0.0 ARG A:95 A:95 86.0 0.382 H -59.6 -41.9