Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 104161650 . C A CCDS783.1:NM_000699.2:c.433Cca>Aca_NP_000690.1:p.145P>T Homo sapiens amylase, alpha 2A (pancreatic) (AMY2A), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1b2y 1 P04746 100.0 0.0 X-RAY
 2000-02-16 PRO A:130 A:130 62.0 0.428 T -100.2 149.6 62.0 0.428 0.0 HOH
 3.888
 CG
 O
1bsi 1 P04746 99.8 0.0 X-RAY
 1999-05-18 PRO A:130 A:130 60.0 0.414 T -99.9 154.7 60.0 0.414 0.0 HOH
 4.722
 O
 O
1cpu 1 P04746 99.8 0.0 X-RAY
 1999-06-14 PRO A:130 A:130 63.0 0.434 T -99.9 152.2 63.0 0.434 0.0 HOH
 3.473
 CD
 O
1hny 1 P04746 99.8 0.0 X-RAY
 1996-03-08 PRO A:130 A:130 63.0 0.434 T -100.4 155.3 63.0 0.434 0.0 HOH
 4.058
 CB
 O
1u2y 1 P04746 99.8 0.0 X-RAY
 2004-09-07 PRO A:130 A:130 62.0 0.428 T -103.7 152.4 62.0 0.428 0.0 HOH
 4.395
 O
 O
1u30 1 P04746 99.8 0.0 X-RAY
 2004-09-07 PRO A:130 A:130 65.0 0.448 T -93.5 142.0 65.0 0.448 0.0 HOH
 4.715
 O
 O
1u33 1 P04746 99.8 0.0 X-RAY
 2004-09-07 PRO A:130 A:130 60.0 0.414 T -98.4 145.9 60.0 0.414 0.0 HOH
 3.512
 CB
 O
1xcw 1 P04746 99.8 0.0 X-RAY
 2004-12-07 PRO A:130 A:130 61.0 0.421 T -102.0 155.0 61.0 0.421 0.0 HOH
 4.305
 CB
 O
1xcx 1 P04746 99.8 0.0 X-RAY
 2004-12-07 PRO A:130 A:130 62.0 0.428 T -103.5 154.6 62.0 0.428 0.0 HOH
 4.438
 O
 O
1xd0 1 P04746 99.8 0.0 X-RAY
 2004-12-07 PRO A:130 A:130 64.0 0.441 T -98.8 144.9 64.0 0.441 0.0 HOH
 4.865
 O
 O
1xd1 1 P04746 99.8 0.0 X-RAY
 2004-12-07 PRO A:130 A:130 60.0 0.414 T -100.6 162.0 60.0 0.414 0.0 HOH
 5.676
 N
 O
2qmk 1 P04746 99.8 0.0 X-RAY
 2008-03-25 PRO A:130 A:130 58.0 0.4 T -102.7 155.1 58.0 0.4 0.0 HOH
 4.239
 CB
 O
2qv4 1 P04746 99.8 0.0 X-RAY
 2008-03-25 PRO A:130 A:130 63.0 0.434 T -100.2 150.5 63.0 0.434 0.0 HOH
 4.357
 CD
 O
3bai 1 P04746 99.8 0.0 X-RAY
 2008-03-25 PRO A:130 A:130 60.0 0.414 T -102.9 156.4 60.0 0.414 0.0 HOH
 4.574
 CB
 O
3baj 1 P04746 99.8 0.0 X-RAY
 2008-03-25 PRO A:130 A:130 62.0 0.428 T -103.2 155.8 62.0 0.428 0.0 HOH
 3.257
 CD
 O
3baw 1 P04746 99.8 0.0 X-RAY
 2008-03-25 PRO A:130 A:130 63.0 0.434 T -101.9 152.7 63.0 0.434 0.0 HOH
 3.277
 O
 O
3ij7 1 P04746 99.8 0.0 X-RAY
 2009-10-27 PRO A:130 A:130 62.0 0.428 T -100.1 147.6 62.0 0.428 0.0 HOH
 4.546
 CB
 O
3ij8 1 P04746 99.8 0.0 X-RAY
 2009-10-27 PRO A:130 A:130 61.0 0.421 T -100.4 150.4 61.0 0.421 0.0 HOH
 4.027
 CB
 O
3ij9 1 P04746 99.8 0.0 X-RAY
 2009-10-27 PRO A:130 A:130 60.0 0.414 T -96.6 149.4 60.0 0.414 0.0 HOH
 3.529
 CD
 O
4gqq 1 P04746 99.8 0.0 X-RAY
 2012-10-24 PRO A:130 A:130 64.0 0.441 T -97.1 137.3 64.0 0.441 0.0 HOH
 4.807
 CB
 O
4gqr 1 P04746 99.8 0.0 X-RAY
 2012-10-24 PRO A:130 A:130 64.0 0.441 T -42.5 91.3 64.0 0.441 0.0 HOH
 3.322
 O
 O
4w93 1 P04746 99.8 0.0 X-RAY
 2015-07-15 PRO A:130 A:130 66.0 0.455 T -80.3 144.6 66.0 0.455 0.0 HOH
 4.775
 N
 O
4x9y 1 P04746 99.8 0.0 X-RAY
 2014-12-31 PRO A:130 A:130 62.0 0.428 T -93.3 147.8 62.0 0.428 0.0 HOH
 2.858
 HB3
 O
5e0f 1 P04746 99.8 0.0 X-RAY
 2016-09-07 PRO A:130 A:130 62.0 0.428 T -91.6 145.1 62.0 0.428 0.0 HOH
 2.831
 HB3
 O
5emy 1 P04746 99.8 0.0 X-RAY
 2016-07-06 PRO A:130 A:130 63.0 0.434 T -95.7 147.9 63.0 0.434 0.0 HOH
 2.957
 HG2
 O
5kez 1 P04746 99.8 0.0 X-RAY
 2017-03-29 PRO A:130 A:130 63.0 0.434 T -90.8 142.3 63.0 0.434 0.0 HOH
 5.033
 N
 O
5u3a 1 P04746 99.8 0.0 X-RAY
 2017-12-06 PRO A:130 A:130 63.0 0.434 T -94.6 147.4 63.0 0.434 0.0 HOH
 2.845
 HB3
 O
5va9 1 P04746 99.8 0.0 X-RAY
 2018-03-28 PRO A:130 A:130 59.0 0.407 T -89.9 145.3 59.0 0.407 0.0 HOH
 3.712
 CD
 O
PRO B:130 B:130 62.0 0.428 T -89.5 144.9 NA NA NA
6obx 1 P04746 99.8 0.0 X-RAY
 2020-02-12 PRO A:130 A:130 63.0 0.434 T -93.9 148.2 63.0 0.434 0.0 HOH
 2.856
 HB3
 O
6ocn 1 P04746 99.8 0.0 X-RAY
 2020-02-12 PRO A:130 A:130 63.0 0.434 T -95.6 146.8 63.0 0.434 0.0 HOH
 2.812
 HB3
 O
3old 1 P04746 99.8 0.0 X-RAY
 2011-04-13 PRO A:130 A:130 63.0 0.434 T -102.4 147.0 63.0 0.434 0.0 GLC
GLC
GLC
HOH
 6.161
3.736
3.751
3.579
 O
CG
CB
CG
 O4
O6
O2
O
3ole 1 P04746 99.8 0.0 X-RAY
 2011-04-13 PRO A:130 A:130 64.0 0.441 T -100.1 148.1 64.0 0.441 0.0 GLC
GLC
GLC
HOH
 6.261
3.732
3.738
3.559
 O
CG
CB
CG
 O4
O6
O2
O
3olg 1 P04746 99.8 0.0 X-RAY
 2011-04-13 PRO A:130 A:130 62.0 0.428 T -103.2 150.9 62.0 0.428 0.0 GLC
GLC
GLC
HOH
 6.084
3.833
3.963
3.705
 O
CG
CB
CG
 O4
O6
O2
O
3oli 1 P04746 99.8 0.0 X-RAY
 2011-04-13 PRO A:130 A:130 64.0 0.441 T -100.4 149.2 64.0 0.441 0.0 GLC
GLC
GLC
HOH
 6.239
3.698
3.779
3.468
 O
CG
CB
CD
 O4
O6
O2
O
1kgw 1 P04746 99.6 0.0 X-RAY
 2002-01-16 PRO A:130 A:130 61.0 0.421 T -99.2 155.6 61.0 0.421 0.0 HOH
 4.523
 O
 O
1xgz 1 P04746 99.6 0.0 X-RAY
 2005-05-24 PRO A:130 A:130 60.0 0.414 T -103.5 157.6 60.0 0.414 0.0 HOH
 3.605
 CD
 O
1xh0 1 P04746 99.6 0.0 X-RAY
 2005-05-24 PRO A:130 A:130 61.0 0.421 T -102.5 155.1 61.0 0.421 0.0 HOH
 4.373
 CB
 O
1xh1 1 P04746 99.6 0.0 X-RAY
 2005-05-24 PRO A:130 A:130 61.0 0.421 T -100.0 154.9 61.0 0.421 0.0 HOH
 3.897
 CG
 O
1xh2 1 P04746 99.6 0.0 X-RAY
 2005-05-24 PRO A:130 A:130 60.0 0.414 T -102.4 154.7 60.0 0.414 0.0 HOH
 4.048
 O
 O
3bak 1 P04746 99.6 0.0 X-RAY
 2008-03-25 PRO A:130 A:130 61.0 0.421 T -103.0 154.8 61.0 0.421 0.0 HOH
 4.617
 CB
 O
3bax 1 P04746 99.6 0.0 X-RAY
 2008-03-25 PRO A:130 A:130 62.0 0.428 T -102.5 151.4 62.0 0.428 0.0 HOH
 3.551
 CD
 O
3bay 1 P04746 99.6 0.0 X-RAY
 2008-03-25 PRO A:130 A:130 62.0 0.428 T -100.6 155.7 62.0 0.428 0.0 HOH
 4.975
 CB
 O
1kgx 1 P04746 99.6 0.0 X-RAY
 2002-01-16 PRO A:130 A:130 60.0 0.414 T -99.3 154.3 60.0 0.414 0.0 HOH
 4.952
 N
 O
6z8l 1 P04746 99.6 0.0 X-RAY
 2020-12-02 PRO A:130 A:130 63.0 0.434 T -95.9 149.4 63.0 0.434 0.0 HOH
 3.530
 HB2
 O
1kgu 1 P04746 99.6 0.0 X-RAY
 2002-01-16 PRO A:130 A:130 62.0 0.428 T -98.1 147.9 62.0 0.428 0.0 HOH
 4.657
 CB
 O
2cpu 1 P04746 99.6 0.0 X-RAY
 2001-06-30 PRO A:130 A:130 61.0 0.421 T -102.0 154.8 61.0 0.421 0.0 HOH
 4.511
 O
 O
3cpu 1 P04746 99.6 0.0 X-RAY
 2001-06-30 PRO A:130 A:130 65.0 0.448 T -97.8 153.8 65.0 0.448 0.0 HOH
 4.096
 O
 O
5td4 1 P04746 99.6 0.0 X-RAY
 2016-11-02 PRO A:130 A:130 63.0 0.434 T -90.7 141.8 63.0 0.434 0.0 GLC
GLC
GLC
GLC
HOH
 6.349
3.589
4.089
8.892
3.599
 O
CG
CB
CB
CG
 O4
O6
C1
C1
O
1kb3 1 P04746 99.6 0.0 X-RAY
 2002-05-01 PRO A:130 A:130 60.0 0.414 T -100.9 154.4 60.0 0.414 0.0 HOH
 3.821
 CD
 O
1kbb 1 P04746 99.6 0.0 X-RAY
 2002-04-10 PRO A:130 A:130 62.0 0.428 T -104.2 149.5 62.0 0.428 0.0 HOH
 4.522
 O
 O
1kbk 1 P04746 99.6 0.0 X-RAY
 2002-04-10 PRO A:130 A:130 61.0 0.421 T -106.3 154.8 61.0 0.421 0.0 HOH
 4.378
 CB
 O
1c8q 1 P04745 96.98 0.0 X-RAY
 2001-06-13 PRO A:130 A:130 63.0 0.434 T -99.7 148.7 63.0 0.434 0.0 HOH
 4.399
 O
 O
1mfv 1 P04745 96.98 0.0 X-RAY
 2002-11-20 PRO A:130 A:130 60.0 0.414 T -97.2 149.8 60.0 0.414 0.0 HOH
 4.857
 O
 O
1smd 1 P04745 96.98 0.0 X-RAY
 1996-07-11 PRO A:130 A:130 61.0 0.421 T -99.3 153.9 61.0 0.421 0.0 HOH
 4.747
 O
 O
1xv8 1 P04745 96.98 0.0 X-RAY
 2005-10-11 PRO A:130 A:130 56.0 0.386 T -104.9 152.1 56.0 0.386 0.0 HOH
 5.813
 N
 O
PRO B:130 B:130 57.0 0.393 T -104.9 152.0 57.0 0.393 0.0 HOH
 5.813
 N
 O
1z32 1 P04745 96.77 0.0 X-RAY
 2005-05-31 PRO A:130 X:130 62.0 0.428 T -95.5 148.8 62.0 0.428 0.0 HOH
 3.564
 O
 O
1jxj 1 P04745 96.77 0.0 X-RAY
 2001-09-14 PRO A:130 A:130 62.0 0.428 T -98.6 157.0 62.0 0.428 0.0 HOH
 3.402
 O
 O
1q4n 1 P04745 96.77 0.0 X-RAY
 2004-03-16 PRO A:130 X:130 66.0 0.455 T -87.2 147.1 66.0 0.455 0.0 HOH
 4.855
 N
 O
1nm9 1 P04745 96.77 0.0 X-RAY
 2004-01-20 PRO A:130 A:130 64.0 0.441 T -91.6 148.4 64.0 0.441 0.0 HOH
 5.021
 N
 O
3blk 1 P04745 96.77 0.0 X-RAY
 2008-11-25 PRO A:130 A:130 64.0 0.441 T -87.1 145.0 64.0 0.441 0.0 HOH
 5.092
 N
 O
3blp 1 P04745 96.77 0.0 X-RAY
 2008-11-18 PRO A:130 X:130 62.0 0.428 T -91.7 148.1 62.0 0.428 0.0 HOH
 3.650
 CB
 O
1jxk 1 P04745 95.97 0.0 X-RAY
 2001-09-14 PRO A:130 A:130 61.0 0.421 T -97.6 157.9 61.0 0.421 0.0 HOH
 3.767
 CB
 O
1mfu 1 P04745 95.97 0.0 X-RAY
 2002-11-20 PRO A:130 A:130 63.0 0.434 T -90.6 148.8 63.0 0.434 0.0 GLC
HOH
 4.031
3.531
 CG
CG
 C2
O
3dhp 1 P04745 95.77 0.0 X-RAY
 2008-07-01 PRO A:130 A:130 63.0 0.434 T -94.4 147.6 63.0 0.434 0.0 HOH
 3.667
 O
 O
1kxq 1 P00690 86.9 0.0 X-RAY
 2002-06-19 PRO A:130 A:130 63.0 0.434 T -102.1 146.8 63.0 0.434 0.0 HOH
 3.659
 CD
 O
PRO B:130 B:130 62.0 0.428 T -100.0 150.9 NA NA NA
PRO C:130 C:130 63.0 0.434 T -100.1 149.6 NA NA NA
PRO D:130 D:130 63.0 0.434 T -100.0 147.7 NA NA NA
1kxt 1 P00690 86.9 0.0 X-RAY
 2002-06-19 PRO A:130 A:130 63.0 0.434 T -103.8 148.1 63.0 0.434 0.0 HOH
 2.531
 CD
 O
PRO C:130 C:130 62.0 0.428 T -101.3 152.9 NA NA NA
PRO E:130 E:130 60.0 0.414 T -101.9 152.9 NA NA NA
1kxv 1 P00690 86.9 0.0 X-RAY
 2002-06-19 PRO A:130 A:130 65.0 0.448 T -97.3 149.3 65.0 0.448 0.0 HOH
 3.337
 CD
 O
PRO B:130 B:130 65.0 0.448 T -101.1 146.5 NA NA NA
1dhk 1 P00690 86.9 0.0 X-RAY
 1997-12-24 PRO A:130 A:130 67.0 0.462 T -100.6 151.5 67.0 0.462 0.0 HOH
 4.026
 O
 H2
1ppi 1 P00690 86.9 0.0 X-RAY
 1995-05-24 PRO A:130 A:130 61.0 0.421 T -95.6 140.3 61.0 0.421 0.0 HOH
 3.686
 CB
 O
1vah 1 P00690 86.69 0.0 X-RAY
 2005-04-26 PRO A:130 A:130 64.0 0.441 T -98.7 152.5 64.0 0.441 0.0 HOH
 6.061
 N
 O
3l2l 1 P00690 86.69 0.0 X-RAY
 2010-04-14 PRO A:130 A:130 64.0 0.441 T -98.1 148.3 64.0 0.441 0.0 HOH
 2.642
 HB3
 O
3l2m 1 P00690 86.69 0.0 X-RAY
 2010-04-14 PRO A:130 A:130 67.0 0.462 T -96.7 149.2 67.0 0.462 0.0 GLC
GLC
GLC
GLC
HOH
 7.669
2.552
2.776
6.721
2.900
 HB2
HB2
HG2
O
HG3
 O4
HO6
H1
H1
O
1ua3 1 P00690 86.69 0.0 X-RAY
 2003-10-14 PRO A:130 A:130 67.0 0.462 T -92.0 143.8 67.0 0.462 0.0 EDO
EDO
HOH
 3.827
6.778
3.785
 O
O
CB
 C1
C1
O
1jfh 1 P00690 86.69 0.0 X-RAY
 1998-12-02 PRO A:130 A:130 61.0 0.421 T -99.1 148.0 61.0 0.421 0.0 HOH
 3.742
 CG
 O
1ose 1 P00690 86.49 0.0 X-RAY
 1997-04-01 PRO A:130 A:130 59.0 0.407 T -100.3 152.4 59.0 0.407 0.0 HOH
 4.000
 O
 O
1hx0 1 P00690 86.49 0.0 X-RAY
 2001-08-08 PRO A:130 A:130 66.0 0.455 T -96.1 148.7 66.0 0.455 0.0 HOH
 3.629
 O
 O
1wo2 1 P00690 86.49 0.0 X-RAY
 2005-03-15 PRO A:130 A:130 66.0 0.455 T -99.0 149.8 66.0 0.455 0.0 HOH
 3.679
 CB
 O
1bvn 1 P00690 86.49 0.0 X-RAY
 1998-09-23 PRO A:130 P:130 60.0 0.414 -94.0 170.5 60.0 0.414 0.0 HOH
 4.008
 CB
 O
1pif 1 P00690 86.29 0.0 X-RAY
 1996-12-07 PRO A:130 A:130 67.0 0.462 T -100.0 154.3 67.0 0.462 0.0 HOH
 3.725
 CB
 O
1pig 1 P00690 86.29 0.0 X-RAY
 1996-12-07 PRO A:130 A:130 66.0 0.455 T -100.5 153.8 66.0 0.455 0.0 HOH
 3.879
 CB
 O
4x0n 1 P00690 86.29 0.0 X-RAY
 2015-11-25 PRO A:130 A:130 64.0 0.441 T -94.3 148.3 64.0 0.441 0.0 HOH
 4.043
 CB
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04746-f1 1 P04746 100.0 0.0 PRO A:145 A:145 68.0 0.469 T -91.8 129.8
af-p19961-f1 1 P19961 98.83 0.0 PRO A:145 A:145 67.0 0.462 T -100.8 113.3
af-p0dte7-f1 1 P0DTE7 96.87 0.0 PRO A:145 A:145 66.0 0.455 T -97.6 122.8
af-p0dte8-f1 1 P0DTE8 96.87 0.0 PRO A:145 A:145 67.0 0.462 T -99.7 116.5
af-p0dub6-f1 1 P0DUB6 96.87 0.0 PRO A:145 A:145 64.0 0.441 T -100.9 111.7