Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 104162263 . C A CCDS783.1:NM_000699.2:c.601Ctc>Atc_NP_000690.1:p.201L>I Homo sapiens amylase, alpha 2A (pancreatic) (AMY2A), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1b2y 1 P04746 100.0 0.0 X-RAY
 2000-02-16 LEU A:186 A:186 0.0 0.0 H -69.5 -42.3 0.0 0.0 0.0 HOH
 5.143
 O
 O
1bsi 1 P04746 99.8 0.0 X-RAY
 1999-05-18 LEU A:186 A:186 0.0 0.0 H -72.7 -40.1 0.0 0.0 0.0 HOH
 4.916
 N
 O
1cpu 1 P04746 99.8 0.0 X-RAY
 1999-06-14 LEU A:186 A:186 0.0 0.0 H -67.9 -43.6 0.0 0.0 0.0 HOH
 5.122
 O
 O
1hny 1 P04746 99.8 0.0 X-RAY
 1996-03-08 LEU A:186 A:186 0.0 0.0 H -69.0 -46.9 0.0 0.0 0.0 HOH
 5.196
 O
 O
1u2y 1 P04746 99.8 0.0 X-RAY
 2004-09-07 LEU A:186 A:186 0.0 0.0 H -68.2 -40.1 0.0 0.0 0.0 HOH
 5.035
 O
 O
1u30 1 P04746 99.8 0.0 X-RAY
 2004-09-07 LEU A:186 A:186 0.0 0.0 H -71.4 -38.8 0.0 0.0 0.0 HOH
 5.127
 O
 O
1u33 1 P04746 99.8 0.0 X-RAY
 2004-09-07 LEU A:186 A:186 0.0 0.0 H -66.1 -46.9 0.0 0.0 0.0 HOH
 5.178
 O
 O
1xcw 1 P04746 99.8 0.0 X-RAY
 2004-12-07 LEU A:186 A:186 0.0 0.0 H -68.1 -44.0 0.0 0.0 0.0 HOH
 5.215
 O
 O
1xcx 1 P04746 99.8 0.0 X-RAY
 2004-12-07 LEU A:186 A:186 0.0 0.0 H -71.0 -42.5 0.0 0.0 0.0 HOH
 5.072
 O
 O
1xd0 1 P04746 99.8 0.0 X-RAY
 2004-12-07 LEU A:186 A:186 0.0 0.0 H -66.6 -44.8 0.0 0.0 0.0 HOH
 5.172
 O
 O
1xd1 1 P04746 99.8 0.0 X-RAY
 2004-12-07 LEU A:186 A:186 0.0 0.0 H -68.5 -42.9 0.0 0.0 0.0 HOH
 5.242
 O
 O
2qmk 1 P04746 99.8 0.0 X-RAY
 2008-03-25 LEU A:186 A:186 0.0 0.0 H -63.9 -44.2 0.0 0.0 0.0 HOH
 5.070
 O
 O
2qv4 1 P04746 99.8 0.0 X-RAY
 2008-03-25 LEU A:186 A:186 0.0 0.0 H -65.2 -43.4 0.0 0.0 0.0 HOH
 5.097
 O
 O
3bai 1 P04746 99.8 0.0 X-RAY
 2008-03-25 LEU A:186 A:186 0.0 0.0 H -69.0 -42.2 0.0 0.0 0.0 HOH
 5.055
 N
 O
3baj 1 P04746 99.8 0.0 X-RAY
 2008-03-25 LEU A:186 A:186 0.0 0.0 H -67.9 -42.6 0.0 0.0 0.0 HOH
 5.096
 O
 O
3baw 1 P04746 99.8 0.0 X-RAY
 2008-03-25 LEU A:186 A:186 0.0 0.0 H -61.0 -42.7 0.0 0.0 0.0 HOH
 4.945
 O
 O
3ij7 1 P04746 99.8 0.0 X-RAY
 2009-10-27 LEU A:186 A:186 0.0 0.0 H -70.5 -45.1 0.0 0.0 0.0 HOH
 5.066
 O
 O
3ij8 1 P04746 99.8 0.0 X-RAY
 2009-10-27 LEU A:186 A:186 0.0 0.0 H -67.5 -44.2 0.0 0.0 0.0 HOH
 5.115
 O
 O
3ij9 1 P04746 99.8 0.0 X-RAY
 2009-10-27 LEU A:186 A:186 0.0 0.0 H -68.3 -44.2 0.0 0.0 0.0 HOH
 5.097
 O
 O
4gqq 1 P04746 99.8 0.0 X-RAY
 2012-10-24 LEU A:186 A:186 0.0 0.0 H -69.2 -42.3 0.0 0.0 0.0 HOH
 5.299
 O
 O
4gqr 1 P04746 99.8 0.0 X-RAY
 2012-10-24 LEU A:186 A:186 0.0 0.0 H -67.6 -43.6 0.0 0.0 0.0 HOH
 5.066
 O
 O
4w93 1 P04746 99.8 0.0 X-RAY
 2015-07-15 LEU A:186 A:186 0.0 0.0 H -67.6 -44.8 0.0 0.0 0.0 HOH
 5.015
 O
 O
4x9y 1 P04746 99.8 0.0 X-RAY
 2014-12-31 LEU A:186 A:186 0.0 0.0 H -65.6 -45.4 0.0 0.0 0.0 HOH
 5.039
 O
 O
5e0f 1 P04746 99.8 0.0 X-RAY
 2016-09-07 LEU A:186 A:186 0.0 0.0 H -66.9 -45.2 0.0 0.0 0.0 HOH
 5.083
 HG
 O
5emy 1 P04746 99.8 0.0 X-RAY
 2016-07-06 LEU A:186 A:186 0.0 0.0 H -69.2 -44.1 0.0 0.0 0.0 HOH
 5.035
 O
 O
5kez 1 P04746 99.8 0.0 X-RAY
 2017-03-29 LEU A:186 A:186 0.0 0.0 H -69.6 -40.8 0.0 0.0 0.0 HOH
 5.130
 O
 O
5u3a 1 P04746 99.8 0.0 X-RAY
 2017-12-06 LEU A:186 A:186 0.0 0.0 H -66.9 -45.4 0.0 0.0 0.0 HOH
 5.007
 O
 O
5va9 1 P04746 99.8 0.0 X-RAY
 2018-03-28 LEU A:186 A:186 0.0 0.0 H -71.8 -38.1 0.0 0.0 0.0 HOH
 5.778
 CD1
 O
LEU B:186 B:186 0.0 0.0 H -71.4 -37.4 NA NA NA
6obx 1 P04746 99.8 0.0 X-RAY
 2020-02-12 LEU A:186 A:186 0.0 0.0 H -66.0 -45.1 0.0 0.0 0.0 HOH
 5.028
 O
 O
6ocn 1 P04746 99.8 0.0 X-RAY
 2020-02-12 LEU A:186 A:186 0.0 0.0 H -66.1 -44.9 0.0 0.0 0.0 HOH
 5.030
 O
 O
3old 1 P04746 99.8 0.0 X-RAY
 2011-04-13 LEU A:186 A:186 0.0 0.0 H -64.1 -47.6 0.0 0.0 0.0 HOH
 5.030
 O
 O
3ole 1 P04746 99.8 0.0 X-RAY
 2011-04-13 LEU A:186 A:186 0.0 0.0 H -63.7 -44.8 0.0 0.0 0.0 HOH
 5.064
 O
 O
3olg 1 P04746 99.8 0.0 X-RAY
 2011-04-13 LEU A:186 A:186 0.0 0.0 H -68.2 -40.6 0.0 0.0 0.0 HOH
 5.082
 O
 O
3oli 1 P04746 99.8 0.0 X-RAY
 2011-04-13 LEU A:186 A:186 0.0 0.0 H -65.2 -43.6 0.0 0.0 0.0 HOH
 5.096
 O
 O
1kgw 1 P04746 99.6 0.0 X-RAY
 2002-01-16 LEU A:186 A:186 0.0 0.0 H -68.7 -44.0 0.0 0.0 0.0 HOH
 5.009
 O
 O
1xgz 1 P04746 99.6 0.0 X-RAY
 2005-05-24 LEU A:186 A:186 0.0 0.0 H -67.0 -43.1 0.0 0.0 0.0 HOH
 5.091
 O
 O
1xh0 1 P04746 99.6 0.0 X-RAY
 2005-05-24 LEU A:186 A:186 0.0 0.0 H -69.3 -41.5 0.0 0.0 0.0 HOH
 5.074
 O
 O
1xh1 1 P04746 99.6 0.0 X-RAY
 2005-05-24 LEU A:186 A:186 0.0 0.0 H -68.6 -43.8 0.0 0.0 0.0 HOH
 5.149
 O
 O
1xh2 1 P04746 99.6 0.0 X-RAY
 2005-05-24 LEU A:186 A:186 0.0 0.0 H -71.3 -41.0 0.0 0.0 0.0 HOH
 5.013
 O
 O
3bak 1 P04746 99.6 0.0 X-RAY
 2008-03-25 LEU A:186 A:186 0.0 0.0 H -66.0 -43.3 0.0 0.0 0.0 HOH
 5.047
 O
 O
3bax 1 P04746 99.6 0.0 X-RAY
 2008-03-25 LEU A:186 A:186 0.0 0.0 H -59.1 -46.1 0.0 0.0 0.0 HOH
 3.761
 CG
 O
3bay 1 P04746 99.6 0.0 X-RAY
 2008-03-25 LEU A:186 A:186 0.0 0.0 H -67.7 -43.5 0.0 0.0 0.0 HOH
 5.044
 O
 O
1kgx 1 P04746 99.6 0.0 X-RAY
 2002-01-16 LEU A:186 A:186 0.0 0.0 H -70.7 -39.3 0.0 0.0 0.0 HOH
 5.164
 O
 O
6z8l 1 P04746 99.6 0.0 X-RAY
 2020-12-02 LEU A:186 A:186 0.0 0.0 H -67.3 -44.3 0.0 0.0 0.0 HOH
 5.088
 O
 O
1kgu 1 P04746 99.6 0.0 X-RAY
 2002-01-16 LEU A:186 A:186 0.0 0.0 H -69.9 -39.0 0.0 0.0 0.0 HOH
 5.152
 O
 O
2cpu 1 P04746 99.6 0.0 X-RAY
 2001-06-30 LEU A:186 A:186 0.0 0.0 H -68.0 -42.0 0.0 0.0 0.0 HOH
 5.112
 O
 O
3cpu 1 P04746 99.6 0.0 X-RAY
 2001-06-30 LEU A:186 A:186 0.0 0.0 H -67.2 -44.2 0.0 0.0 0.0 HOH
 5.169
 O
 O
5td4 1 P04746 99.6 0.0 X-RAY
 2016-11-02 LEU A:186 A:186 0.0 0.0 H -62.7 -46.3 0.0 0.0 0.0 HOH
 5.126
 O
 O
1kb3 1 P04746 99.6 0.0 X-RAY
 2002-05-01 LEU A:186 A:186 0.0 0.0 H -72.2 -40.4 0.0 0.0 0.0 HOH
 4.973
 N
 O
1kbb 1 P04746 99.6 0.0 X-RAY
 2002-04-10 LEU A:186 A:186 0.0 0.0 H -66.2 -43.2 0.0 0.0 0.0 HOH
 5.145
 O
 O
1kbk 1 P04746 99.6 0.0 X-RAY
 2002-04-10 LEU A:186 A:186 0.0 0.0 H -64.2 -43.6 0.0 0.0 0.0 HOH
 5.193
 O
 O
1c8q 1 P04745 96.98 0.0 X-RAY
 2001-06-13 LEU A:186 A:186 0.0 0.0 H -64.7 -45.2 0.0 0.0 0.0 HOH
 5.103
 O
 O
1mfv 1 P04745 96.98 0.0 X-RAY
 2002-11-20 LEU A:186 A:186 0.0 0.0 H -61.7 -49.0 0.0 0.0 0.0 HOH
 5.110
 O
 O
1smd 1 P04745 96.98 0.0 X-RAY
 1996-07-11 LEU A:186 A:186 0.0 0.0 H -61.3 -46.4 0.0 0.0 0.0 HOH
 5.101
 O
 O
1xv8 1 P04745 96.98 0.0 X-RAY
 2005-10-11 LEU A:186 A:186 0.0 0.0 H -53.0 -56.6 0.0 0.0 0.0 HOH
 5.839
 CD1
 O
LEU B:186 B:186 0.0 0.0 H -53.1 -56.5 0.0 0.0 0.0 HOH
 5.839
 CD1
 O
1z32 1 P04745 96.77 0.0 X-RAY
 2005-05-31 LEU A:186 X:186 0.0 0.0 H -66.2 -45.8 0.0 0.0 0.0 HOH
 5.119
 O
 O
1jxj 1 P04745 96.77 0.0 X-RAY
 2001-09-14 LEU A:186 A:186 0.0 0.0 H -61.9 -48.9 0.0 0.0 0.0 HOH
 5.037
 O
 O
1q4n 1 P04745 96.77 0.0 X-RAY
 2004-03-16 LEU A:186 X:186 0.0 0.0 H -64.3 -43.9 0.0 0.0 0.0 HOH
 5.013
 O
 O
1nm9 1 P04745 96.77 0.0 X-RAY
 2004-01-20 LEU A:186 A:186 0.0 0.0 H -61.5 -45.7 0.0 0.0 0.0 HOH
 5.177
 O
 O
3blk 1 P04745 96.77 0.0 X-RAY
 2008-11-25 LEU A:186 A:186 0.0 0.0 H -61.8 -48.8 0.0 0.0 0.0 HOH
 5.136
 O
 O
3blp 1 P04745 96.77 0.0 X-RAY
 2008-11-18 LEU A:186 X:186 0.0 0.0 H -64.0 -47.0 0.0 0.0 0.0 HOH
 5.096
 O
 O
1jxk 1 P04745 95.97 0.0 X-RAY
 2001-09-14 LEU A:186 A:186 0.0 0.0 H -66.3 -46.8 0.0 0.0 0.0 HOH
 5.113
 O
 O
1mfu 1 P04745 95.97 0.0 X-RAY
 2002-11-20 LEU A:186 A:186 0.0 0.0 H -60.5 -48.1 0.0 0.0 0.0 HOH
 5.063
 O
 O
3dhp 1 P04745 95.77 0.0 X-RAY
 2008-07-01 LEU A:186 A:186 0.0 0.0 H -66.1 -44.5 0.0 0.0 0.0 HOH
 5.079
 O
 O
1kxq 1 P00690 86.9 0.0 X-RAY
 2002-06-19 LEU A:186 A:186 0.0 0.0 H -67.6 -44.4 0.0 0.0 0.0 HOH
 4.926
 N
 O
LEU B:186 B:186 0.0 0.0 H -61.5 -43.6 NA NA NA
LEU C:186 C:186 0.0 0.0 H -66.1 -42.0 NA NA NA
LEU D:186 D:186 0.0 0.0 H -68.8 -43.2 NA NA NA
1kxt 1 P00690 86.9 0.0 X-RAY
 2002-06-19 LEU A:186 A:186 0.0 0.0 H -60.9 -49.7 0.0 0.0 0.0 HOH
 5.158
 O
 O
LEU C:186 C:186 0.0 0.0 H -64.1 -48.4 NA NA NA
LEU E:186 E:186 0.0 0.0 H -66.7 -42.0 NA NA NA
1kxv 1 P00690 86.9 0.0 X-RAY
 2002-06-19 LEU A:186 A:186 0.0 0.0 H -61.0 -41.8 0.0 0.0 0.0 HOH
 4.971
 N
 O
LEU B:186 B:186 0.0 0.0 H -62.4 -44.4 NA NA NA
1dhk 1 P00690 86.9 0.0 X-RAY
 1997-12-24 LEU A:186 A:186 0.0 0.0 H -68.6 -45.1 0.0 0.0 0.0 HOH
 3.932
 N
 H1
1ppi 1 P00690 86.9 0.0 X-RAY
 1995-05-24 LEU A:186 A:186 0.0 0.0 H -66.2 -44.1 0.0 0.0 0.0 HOH
 5.044
 N
 O
1vah 1 P00690 86.69 0.0 X-RAY
 2005-04-26 LEU A:186 A:186 0.0 0.0 H -62.7 -39.9 0.0 0.0 0.0 HOH
 5.176
 O
 O
3l2l 1 P00690 86.69 0.0 X-RAY
 2010-04-14 LEU A:186 A:186 0.0 0.0 H -71.5 -41.5 0.0 0.0 0.0 HOH
 4.975
 N
 O
3l2m 1 P00690 86.69 0.0 X-RAY
 2010-04-14 LEU A:186 A:186 0.0 0.0 H -65.3 -45.6 0.0 0.0 0.0 HOH
 4.908
 N
 O
1ua3 1 P00690 86.69 0.0 X-RAY
 2003-10-14 LEU A:186 A:186 0.0 0.0 H -62.8 -44.6 0.0 0.0 0.0 HOH
 5.052
 N
 O
1jfh 1 P00690 86.69 0.0 X-RAY
 1998-12-02 LEU A:186 A:186 0.0 0.0 H -65.0 -43.7 0.0 0.0 0.0 HOH
 5.044
 N
 O
1ose 1 P00690 86.49 0.0 X-RAY
 1997-04-01 LEU A:186 A:186 0.0 0.0 H -65.5 -47.0 0.0 0.0 0.0 HOH
 5.091
 N
 O
1hx0 1 P00690 86.49 0.0 X-RAY
 2001-08-08 LEU A:186 A:186 0.0 0.0 H -64.7 -44.0 0.0 0.0 0.0 HOH
 4.939
 N
 O
1wo2 1 P00690 86.49 0.0 X-RAY
 2005-03-15 LEU A:186 A:186 0.0 0.0 H -63.2 -46.3 0.0 0.0 0.0 HOH
 4.884
 N
 O
1bvn 1 P00690 86.49 0.0 X-RAY
 1998-09-23 LEU A:186 P:186 0.0 0.0 H -61.0 -32.2 0.0 0.0 0.0 HOH
 5.120
 O
 O
1pif 1 P00690 86.29 0.0 X-RAY
 1996-12-07 LEU A:186 A:186 0.0 0.0 H -66.4 -47.9 0.0 0.0 0.0 HOH
 4.873
 N
 O
1pig 1 P00690 86.29 0.0 X-RAY
 1996-12-07 LEU A:186 A:186 0.0 0.0 H -66.4 -46.6 0.0 0.0 0.0 HOH
 5.081
 O
 O
4x0n 1 P00690 86.29 0.0 X-RAY
 2015-11-25 LEU A:186 A:186 0.0 0.0 H -63.9 -44.3 0.0 0.0 0.0 HOH
 5.368
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04746-f1 1 P04746 100.0 0.0 LEU A:201 A:201 0.0 0.0 H -66.6 -42.2
af-p19961-f1 1 P19961 98.83 0.0 LEU A:201 A:201 0.0 0.0 H -67.7 -42.1
af-p0dte7-f1 1 P0DTE7 96.87 0.0 LEU A:201 A:201 0.0 0.0 H -68.2 -41.7
af-p0dte8-f1 1 P0DTE8 96.87 0.0 LEU A:201 A:201 0.0 0.0 H -68.1 -42.0
af-p0dub6-f1 1 P0DUB6 96.87 0.0 LEU A:201 A:201 0.0 0.0 H -67.3 -42.0