Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 104162275 . G A CCDS783.1:NM_000699.2:c.613Ggt>Agt_NP_000690.1:p.205G>S Homo sapiens amylase, alpha 2A (pancreatic) (AMY2A), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1b2y 1 P04746 100.0 0.0 X-RAY
 2000-02-16 GLY A:190 A:190 0.0 0.0 T 128.5 11.2 0.0 0.0 0.0 HOH
 2.901
 O
 O
1bsi 1 P04746 99.8 0.0 X-RAY
 1999-05-18 GLY A:190 A:190 0.0 0.0 T 127.4 5.7 0.0 0.0 0.0 HOH
 2.893
 O
 O
1cpu 1 P04746 99.8 0.0 X-RAY
 1999-06-14 GLY A:190 A:190 0.0 0.0 T 133.0 4.1 0.0 0.0 0.0 HOH
 2.818
 O
 O
1hny 1 P04746 99.8 0.0 X-RAY
 1996-03-08 GLY A:190 A:190 0.0 0.0 T 134.5 9.1 0.0 0.0 0.0 HOH
 2.959
 O
 O
1u2y 1 P04746 99.8 0.0 X-RAY
 2004-09-07 GLY A:190 A:190 0.0 0.0 T 132.9 2.2 0.0 0.0 0.0 HOH
 2.802
 O
 O
1u30 1 P04746 99.8 0.0 X-RAY
 2004-09-07 GLY A:190 A:190 0.0 0.0 T 132.1 6.1 0.0 0.0 0.0 HOH
 2.992
 O
 O
1u33 1 P04746 99.8 0.0 X-RAY
 2004-09-07 GLY A:190 A:190 0.0 0.0 T 135.3 -1.0 0.0 0.0 0.0 HOH
 2.789
 O
 O
1xcw 1 P04746 99.8 0.0 X-RAY
 2004-12-07 GLY A:190 A:190 0.0 0.0 T 132.7 4.0 0.0 0.0 0.0 HOH
 2.902
 O
 O
1xcx 1 P04746 99.8 0.0 X-RAY
 2004-12-07 GLY A:190 A:190 0.0 0.0 T 132.7 6.5 0.0 0.0 0.0 HOH
 2.830
 O
 O
1xd0 1 P04746 99.8 0.0 X-RAY
 2004-12-07 GLY A:190 A:190 0.0 0.0 T 131.7 5.4 0.0 0.0 0.0 HOH
 2.926
 O
 O
1xd1 1 P04746 99.8 0.0 X-RAY
 2004-12-07 GLY A:190 A:190 0.0 0.0 T 131.9 -0.4 0.0 0.0 0.0 HOH
 2.870
 O
 O
2qmk 1 P04746 99.8 0.0 X-RAY
 2008-03-25 GLY A:190 A:190 0.0 0.0 T 123.0 11.3 0.0 0.0 0.0 HOH
 2.996
 O
 O
2qv4 1 P04746 99.8 0.0 X-RAY
 2008-03-25 GLY A:190 A:190 0.0 0.0 T 131.5 0.6 0.0 0.0 0.0 HOH
 2.728
 O
 O
3bai 1 P04746 99.8 0.0 X-RAY
 2008-03-25 GLY A:190 A:190 0.0 0.0 T 129.6 0.6 0.0 0.0 0.0 HOH
 2.797
 O
 O
3baj 1 P04746 99.8 0.0 X-RAY
 2008-03-25 GLY A:190 A:190 0.0 0.0 T 130.5 1.2 0.0 0.0 0.0 HOH
 2.905
 O
 O
3baw 1 P04746 99.8 0.0 X-RAY
 2008-03-25 GLY A:190 A:190 0.0 0.0 T 123.3 3.6 0.0 0.0 0.0 HOH
 2.861
 O
 O
3ij7 1 P04746 99.8 0.0 X-RAY
 2009-10-27 GLY A:190 A:190 0.0 0.0 T 133.9 2.6 0.0 0.0 0.0 HOH
 2.797
 O
 O
3ij8 1 P04746 99.8 0.0 X-RAY
 2009-10-27 GLY A:190 A:190 0.0 0.0 T 135.1 1.1 0.0 0.0 0.0 HOH
 2.864
 O
 O
3ij9 1 P04746 99.8 0.0 X-RAY
 2009-10-27 GLY A:190 A:190 0.0 0.0 T 136.0 -0.8 0.0 0.0 0.0 HOH
 2.876
 O
 O
4gqq 1 P04746 99.8 0.0 X-RAY
 2012-10-24 GLY A:190 A:190 0.0 0.0 T 135.6 5.3 0.0 0.0 0.0 HOH
 2.794
 O
 O
4gqr 1 P04746 99.8 0.0 X-RAY
 2012-10-24 GLY A:190 A:190 0.0 0.0 T 129.5 2.5 0.0 0.0 0.0 HOH
 2.786
 O
 O
4w93 1 P04746 99.8 0.0 X-RAY
 2015-07-15 GLY A:190 A:190 0.0 0.0 T 119.7 15.4 0.0 0.0 0.0 HOH
 2.806
 O
 O
4x9y 1 P04746 99.8 0.0 X-RAY
 2014-12-31 GLY A:190 A:190 0.0 0.0 T 127.4 10.4 0.0 0.0 0.0 HOH
 2.651
 HA2
 O
5e0f 1 P04746 99.8 0.0 X-RAY
 2016-09-07 GLY A:190 A:190 0.0 0.0 T 135.0 13.2 0.0 0.0 0.0 HOH
 2.723
 HA2
 O
5emy 1 P04746 99.8 0.0 X-RAY
 2016-07-06 GLY A:190 A:190 0.0 0.0 T 130.0 7.2 0.0 0.0 0.0 HOH
 2.688
 HA2
 O
5kez 1 P04746 99.8 0.0 X-RAY
 2017-03-29 GLY A:190 A:190 0.0 0.0 T 130.5 14.2 0.0 0.0 0.0 HOH
 2.897
 O
 O
5u3a 1 P04746 99.8 0.0 X-RAY
 2017-12-06 GLY A:190 A:190 0.0 0.0 T 130.2 8.5 0.0 0.0 0.0 HOH
 2.665
 HA2
 O
5va9 1 P04746 99.8 0.0 X-RAY
 2018-03-28 GLY A:190 A:190 0.0 0.0 T 123.6 10.1 0.0 0.0 0.0 HOH
 2.554
 O
 O
GLY B:190 B:190 0.0 0.0 T 124.4 10.4 NA NA NA
6obx 1 P04746 99.8 0.0 X-RAY
 2020-02-12 GLY A:190 A:190 0.0 0.0 T 128.7 8.9 0.0 0.0 0.0 HOH
 2.693
 HA2
 O
6ocn 1 P04746 99.8 0.0 X-RAY
 2020-02-12 GLY A:190 A:190 0.0 0.0 T 129.0 10.0 0.0 0.0 0.0 HOH
 2.647
 HA2
 O
3old 1 P04746 99.8 0.0 X-RAY
 2011-04-13 GLY A:190 A:190 0.0 0.0 T 131.9 0.2 0.0 0.0 0.0 HOH
 2.768
 O
 O
3ole 1 P04746 99.8 0.0 X-RAY
 2011-04-13 GLY A:190 A:190 0.0 0.0 T 128.6 5.4 0.0 0.0 0.0 HOH
 2.784
 O
 O
3olg 1 P04746 99.8 0.0 X-RAY
 2011-04-13 GLY A:190 A:190 0.0 0.0 T 130.5 4.8 0.0 0.0 0.0 HOH
 2.891
 O
 O
3oli 1 P04746 99.8 0.0 X-RAY
 2011-04-13 GLY A:190 A:190 0.0 0.0 T 133.9 6.4 0.0 0.0 0.0 MPD
HOH
 9.012
2.851
 CA
O
 O4
O
1kgw 1 P04746 99.6 0.0 X-RAY
 2002-01-16 GLY A:190 A:190 0.0 0.0 T 135.0 5.0 0.0 0.0 0.0 HOH
 2.872
 O
 O
1xgz 1 P04746 99.6 0.0 X-RAY
 2005-05-24 GLY A:190 A:190 0.0 0.0 T 132.1 2.7 0.0 0.0 0.0 HOH
 2.905
 O
 O
1xh0 1 P04746 99.6 0.0 X-RAY
 2005-05-24 GLY A:190 A:190 0.0 0.0 T 130.4 7.1 0.0 0.0 0.0 HOH
 2.950
 O
 O
1xh1 1 P04746 99.6 0.0 X-RAY
 2005-05-24 GLY A:190 A:190 0.0 0.0 T 132.4 -2.6 0.0 0.0 0.0 HOH
 2.947
 O
 O
1xh2 1 P04746 99.6 0.0 X-RAY
 2005-05-24 GLY A:190 A:190 0.0 0.0 T 133.4 -0.2 0.0 0.0 0.0 HOH
 2.938
 O
 O
3bak 1 P04746 99.6 0.0 X-RAY
 2008-03-25 GLY A:190 A:190 0.0 0.0 T 131.9 -0.6 0.0 0.0 0.0 HOH
 2.941
 O
 O
3bax 1 P04746 99.6 0.0 X-RAY
 2008-03-25 GLY A:190 A:190 0.0 0.0 T 125.4 -5.5 0.0 0.0 0.0 HOH
 2.832
 O
 O
3bay 1 P04746 99.6 0.0 X-RAY
 2008-03-25 GLY A:190 A:190 0.0 0.0 T 133.6 -3.8 0.0 0.0 0.0 HOH
 3.082
 O
 O
1kgx 1 P04746 99.6 0.0 X-RAY
 2002-01-16 GLY A:190 A:190 0.0 0.0 T 132.7 -1.9 0.0 0.0 0.0 HOH
 2.886
 O
 O
6z8l 1 P04746 99.6 0.0 X-RAY
 2020-12-02 GLY A:190 A:190 0.0 0.0 T 131.4 10.3 0.0 0.0 0.0 HOH
 2.696
 HA2
 O
1kgu 1 P04746 99.6 0.0 X-RAY
 2002-01-16 GLY A:190 A:190 0.0 0.0 T 131.0 8.1 0.0 0.0 0.0 HOH
 2.828
 O
 O
2cpu 1 P04746 99.6 0.0 X-RAY
 2001-06-30 GLY A:190 A:190 0.0 0.0 T 130.2 6.2 0.0 0.0 0.0 HOH
 2.834
 O
 O
3cpu 1 P04746 99.6 0.0 X-RAY
 2001-06-30 GLY A:190 A:190 0.0 0.0 T 135.2 0.9 0.0 0.0 0.0 HOH
 2.813
 O
 O
5td4 1 P04746 99.6 0.0 X-RAY
 2016-11-02 GLY A:190 A:190 0.0 0.0 T 132.2 18.2 0.0 0.0 0.0 HOH
 2.404
 O
 O
1kb3 1 P04746 99.6 0.0 X-RAY
 2002-05-01 GLY A:190 A:190 0.0 0.0 T 135.6 -5.9 0.0 0.0 0.0 HOH
 2.906
 O
 O
1kbb 1 P04746 99.6 0.0 X-RAY
 2002-04-10 GLY A:190 A:190 0.0 0.0 T 134.8 6.6 0.0 0.0 0.0 HOH
 2.737
 O
 O
1kbk 1 P04746 99.6 0.0 X-RAY
 2002-04-10 GLY A:190 A:190 0.0 0.0 T 130.8 4.1 0.0 0.0 0.0 HOH
 2.977
 O
 O
1c8q 1 P04745 96.98 0.0 X-RAY
 2001-06-13 GLY A:190 A:190 0.0 0.0 T 133.7 -1.2 0.0 0.0 0.0 HOH
 2.777
 O
 O
1mfv 1 P04745 96.98 0.0 X-RAY
 2002-11-20 GLY A:190 A:190 0.0 0.0 T 130.1 13.7 0.0 0.0 0.0 HOH
 2.784
 O
 O
1smd 1 P04745 96.98 0.0 X-RAY
 1996-07-11 GLY A:190 A:190 0.0 0.0 T 132.2 7.4 0.0 0.0 0.0 HOH
 2.830
 O
 O
1xv8 1 P04745 96.98 0.0 X-RAY
 2005-10-11 GLY A:190 A:190 0.0 0.0 T 139.4 15.0 0.0 0.0 0.0 HOH
 7.935
 N
 O
GLY B:190 B:190 0.0 0.0 T 139.4 14.9 0.0 0.0 0.0 HOH
 7.934
 N
 O
1z32 1 P04745 96.77 0.0 X-RAY
 2005-05-31 GLY A:190 X:190 0.0 0.0 T 129.6 12.1 0.0 0.0 0.0 HOH
 2.828
 O
 O
1jxj 1 P04745 96.77 0.0 X-RAY
 2001-09-14 GLY A:190 A:190 0.0 0.0 T 137.0 7.0 0.0 0.0 0.0 HOH
 2.835
 O
 O
1q4n 1 P04745 96.77 0.0 X-RAY
 2004-03-16 GLY A:190 X:190 0.0 0.0 T 136.3 0.2 0.0 0.0 0.0 HOH
 2.776
 O
 O
1nm9 1 P04745 96.77 0.0 X-RAY
 2004-01-20 GLY A:190 A:190 0.0 0.0 T 130.6 14.5 0.0 0.0 0.0 HOH
 2.783
 O
 O
3blk 1 P04745 96.77 0.0 X-RAY
 2008-11-25 GLY A:190 A:190 0.0 0.0 T 131.7 16.5 0.0 0.0 0.0 HOH
 2.793
 O
 O
3blp 1 P04745 96.77 0.0 X-RAY
 2008-11-18 GLY A:190 X:190 0.0 0.0 T 129.2 9.3 0.0 0.0 0.0 HOH
 2.866
 O
 O
1jxk 1 P04745 95.97 0.0 X-RAY
 2001-09-14 GLY A:190 A:190 0.0 0.0 T 139.1 7.3 0.0 0.0 0.0 HOH
 2.844
 O
 O
1mfu 1 P04745 95.97 0.0 X-RAY
 2002-11-20 GLY A:190 A:190 0.0 0.0 T 134.9 6.7 0.0 0.0 0.0 HOH
 2.746
 O
 O
3dhp 1 P04745 95.77 0.0 X-RAY
 2008-07-01 GLY A:190 A:190 0.0 0.0 T 130.1 8.0 0.0 0.0 0.0 HOH
 2.852
 O
 O
1kxq 1 P00690 86.9 0.0 X-RAY
 2002-06-19 GLY A:190 A:190 0.0 0.0 T 134.5 5.7 0.0 0.0 0.0 HOH
 2.690
 O
 O
GLY B:190 B:190 0.0 0.0 T 133.0 5.0 NA NA NA
GLY C:190 C:190 0.0 0.0 T 133.8 4.0 NA NA NA
GLY D:190 D:190 0.0 0.0 T 133.4 3.3 NA NA NA
1kxt 1 P00690 86.9 0.0 X-RAY
 2002-06-19 GLY A:190 A:190 0.0 0.0 T 136.7 -14.6 0.0 0.0 0.0 HOH
 3.161
 O
 O
GLY C:190 C:190 0.0 0.0 T 138.1 -3.8 NA NA NA
GLY E:190 E:190 0.0 0.0 T 133.9 -5.3 NA NA NA
1kxv 1 P00690 86.9 0.0 X-RAY
 2002-06-19 GLY A:190 A:190 0.0 0.0 T 123.1 9.7 0.0 0.0 0.0 HOH
 2.800
 O
 O
GLY B:190 B:190 0.0 0.0 T 133.4 7.6 NA NA NA
1dhk 1 P00690 86.9 0.0 X-RAY
 1997-12-24 GLY A:190 A:190 0.0 0.0 T 128.1 5.8 0.0 0.0 0.0 HOH
 2.251
 O
 H1
1ppi 1 P00690 86.9 0.0 X-RAY
 1995-05-24 GLY A:190 A:190 0.0 0.0 T 127.2 11.2 0.0 0.0 0.0 HOH
 2.781
 O
 O
1vah 1 P00690 86.69 0.0 X-RAY
 2005-04-26 GLY A:190 A:190 0.0 0.0 T 132.1 11.3 0.0 0.0 0.0 HOH
 3.662
 C
 O
3l2l 1 P00690 86.69 0.0 X-RAY
 2010-04-14 GLY A:190 A:190 0.0 0.0 T 131.6 10.0 0.0 0.0 0.0 HOH
 2.692
 HA2
 O
3l2m 1 P00690 86.69 0.0 X-RAY
 2010-04-14 GLY A:190 A:190 0.0 0.0 T 133.0 11.3 0.0 0.0 0.0 HOH
 2.768
 HA2
 O
1ua3 1 P00690 86.69 0.0 X-RAY
 2003-10-14 GLY A:190 A:190 0.0 0.0 T 132.2 10.4 0.0 0.0 0.0 HOH
 2.812
 O
 O
1jfh 1 P00690 86.69 0.0 X-RAY
 1998-12-02 GLY A:190 A:190 0.0 0.0 T 133.6 3.5 0.0 0.0 0.0 HOH
 2.769
 O
 O
1ose 1 P00690 86.49 0.0 X-RAY
 1997-04-01 GLY A:190 A:190 0.0 0.0 T 135.3 1.8 0.0 0.0 0.0 HOH
 2.946
 O
 O
1hx0 1 P00690 86.49 0.0 X-RAY
 2001-08-08 GLY A:190 A:190 0.0 0.0 T 133.7 8.7 0.0 0.0 0.0 HOH
 2.819
 O
 O
1wo2 1 P00690 86.49 0.0 X-RAY
 2005-03-15 GLY A:190 A:190 0.0 0.0 T 136.7 -0.1 0.0 0.0 0.0 HOH
 2.795
 O
 O
1bvn 1 P00690 86.49 0.0 X-RAY
 1998-09-23 GLY A:190 P:190 0.0 0.0 T 126.6 7.5 0.0 0.0 0.0 HOH
 2.700
 O
 O
1pif 1 P00690 86.29 0.0 X-RAY
 1996-12-07 GLY A:190 A:190 0.0 0.0 T 137.0 9.2 0.0 0.0 0.0 HOH
 2.812
 O
 O
1pig 1 P00690 86.29 0.0 X-RAY
 1996-12-07 GLY A:190 A:190 0.0 0.0 T 133.6 4.7 0.0 0.0 0.0 HOH
 2.687
 O
 O
4x0n 1 P00690 86.29 0.0 X-RAY
 2015-11-25 GLY A:190 A:190 0.0 0.0 T 133.0 9.7 0.0 0.0 0.0 HOH
 2.887
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04746-f1 1 P04746 100.0 0.0 GLY A:205 A:205 0.0 0.0 T 124.5 16.6
af-p19961-f1 1 P19961 98.83 0.0 GLY A:205 A:205 0.0 0.0 T 124.8 16.8
af-p0dte7-f1 1 P0DTE7 96.87 0.0 GLY A:205 A:205 0.0 0.0 T 124.3 16.9
af-p0dte8-f1 1 P0DTE8 96.87 0.0 GLY A:205 A:205 0.0 0.0 T 124.7 17.0
af-p0dub6-f1 1 P0DUB6 96.87 0.0 GLY A:205 A:205 0.0 0.0 T 122.4 15.9