Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 104163260 . G A CCDS783.1:NM_000699.2:c.832Ggc>Agc_NP_000690.1:p.278G>S Homo sapiens amylase, alpha 2A (pancreatic) (AMY2A), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1b2y 1 P04746 100.0 0.0 X-RAY
 2000-02-16 GLY A:263 A:263 1.0 0.013 H -65.0 -41.8 1.0 0.013 0.0 HOH
 7.604
 C
 O
1bsi 1 P04746 99.8 0.0 X-RAY
 1999-05-18 GLY A:263 A:263 1.0 0.013 H -63.2 -48.2 1.0 0.013 0.0 HOH
 4.033
 N
 O
1cpu 1 P04746 99.8 0.0 X-RAY
 1999-06-14 GLY A:263 A:263 1.0 0.013 H -64.5 -39.4 1.0 0.013 0.0 HOH
 4.030
 N
 O
1hny 1 P04746 99.8 0.0 X-RAY
 1996-03-08 GLY A:263 A:263 1.0 0.013 H -59.4 -45.7 1.0 0.013 0.0 HOH
 3.906
 CA
 O
1u2y 1 P04746 99.8 0.0 X-RAY
 2004-09-07 GLY A:263 A:263 1.0 0.013 H -65.1 -43.4 1.0 0.013 0.0 HOH
 4.101
 CA
 O
1u30 1 P04746 99.8 0.0 X-RAY
 2004-09-07 GLY A:263 A:263 1.0 0.013 H -67.7 -45.2 1.0 0.013 0.0 HOH
 4.167
 CA
 O
1u33 1 P04746 99.8 0.0 X-RAY
 2004-09-07 GLY A:263 A:263 2.0 0.027 H -68.6 -46.5 2.0 0.027 0.0 HOH
 3.951
 CA
 O
1xcw 1 P04746 99.8 0.0 X-RAY
 2004-12-07 GLY A:263 A:263 2.0 0.027 H -63.9 -44.1 2.0 0.027 0.0 HOH
 4.128
 CA
 O
1xcx 1 P04746 99.8 0.0 X-RAY
 2004-12-07 GLY A:263 A:263 2.0 0.027 H -64.8 -46.1 2.0 0.027 0.0 HOH
 4.216
 CA
 O
1xd0 1 P04746 99.8 0.0 X-RAY
 2004-12-07 GLY A:263 A:263 1.0 0.013 H -68.8 -39.4 1.0 0.013 0.0 HOH
 4.119
 CA
 O
1xd1 1 P04746 99.8 0.0 X-RAY
 2004-12-07 GLY A:263 A:263 2.0 0.027 H -63.1 -48.0 2.0 0.027 0.0 HOH
 3.988
 CA
 O
2qmk 1 P04746 99.8 0.0 X-RAY
 2008-03-25 GLY A:263 A:263 1.0 0.013 H -72.2 -29.6 1.0 0.013 0.0 HOH
 4.092
 CA
 O
2qv4 1 P04746 99.8 0.0 X-RAY
 2008-03-25 GLY A:263 A:263 1.0 0.013 H -67.1 -45.7 1.0 0.013 0.0 HOH
 3.852
 CA
 O
3bai 1 P04746 99.8 0.0 X-RAY
 2008-03-25 GLY A:263 A:263 2.0 0.027 H -62.3 -44.6 2.0 0.027 0.0 HOH
 4.123
 CA
 O
3baj 1 P04746 99.8 0.0 X-RAY
 2008-03-25 GLY A:263 A:263 2.0 0.027 H -57.1 -46.3 2.0 0.027 0.0 HOH
 4.119
 CA
 O
3baw 1 P04746 99.8 0.0 X-RAY
 2008-03-25 GLY A:263 A:263 1.0 0.013 H -66.3 -48.1 1.0 0.013 0.0 HOH
 3.945
 CA
 O
3ij7 1 P04746 99.8 0.0 X-RAY
 2009-10-27 GLY A:263 A:263 2.0 0.027 H -65.2 -44.3 2.0 0.027 0.0 HOH
 4.066
 CA
 O
3ij8 1 P04746 99.8 0.0 X-RAY
 2009-10-27 GLY A:263 A:263 2.0 0.027 H -63.1 -42.8 2.0 0.027 0.0 HOH
 3.954
 CA
 O
3ij9 1 P04746 99.8 0.0 X-RAY
 2009-10-27 GLY A:263 A:263 1.0 0.013 H -64.2 -47.2 1.0 0.013 0.0 HOH
 3.900
 CA
 O
4gqq 1 P04746 99.8 0.0 X-RAY
 2012-10-24 GLY A:263 A:263 13.0 0.173 H -71.7 -42.7 13.0 0.173 0.0 HOH
 7.235
 O
 O
4gqr 1 P04746 99.8 0.0 X-RAY
 2012-10-24 GLY A:263 A:263 1.0 0.013 H -68.5 -45.6 1.0 0.013 0.0 HOH
 3.966
 CA
 O
4w93 1 P04746 99.8 0.0 X-RAY
 2015-07-15 GLY A:263 A:263 1.0 0.013 H -57.3 -45.4 1.0 0.013 0.0 HOH
 3.761
 CA
 O
4x9y 1 P04746 99.8 0.0 X-RAY
 2014-12-31 GLY A:263 A:263 2.0 0.027 H -63.2 -46.5 2.0 0.027 0.0 HOH
 3.499
 HA3
 O
5e0f 1 P04746 99.8 0.0 X-RAY
 2016-09-07 GLY A:263 A:263 1.0 0.013 H -59.7 -45.5 1.0 0.013 0.0 HOH
 3.326
 HA3
 O
5emy 1 P04746 99.8 0.0 X-RAY
 2016-07-06 GLY A:263 A:263 2.0 0.027 H -65.5 -44.5 2.0 0.027 0.0 HOH
 3.543
 HA3
 O
5kez 1 P04746 99.8 0.0 X-RAY
 2017-03-29 GLY A:263 A:263 1.0 0.013 H -63.2 -46.7 1.0 0.013 0.0 HOH
 3.971
 CA
 O
5u3a 1 P04746 99.8 0.0 X-RAY
 2017-12-06 GLY A:263 A:263 1.0 0.013 H -62.3 -45.8 1.0 0.013 0.0 HOH
 3.422
 HA3
 O
5va9 1 P04746 99.8 0.0 X-RAY
 2018-03-28 GLY A:263 A:263 2.0 0.027 H -65.3 -46.7 2.0 0.027 0.0 HOH
 7.051
 O
 O
GLY B:263 B:263 1.0 0.013 H -64.8 -46.7 NA NA NA
6obx 1 P04746 99.8 0.0 X-RAY
 2020-02-12 GLY A:263 A:263 1.0 0.013 H -64.7 -44.6 1.0 0.013 0.0 HOH
 3.485
 HA3
 O
6ocn 1 P04746 99.8 0.0 X-RAY
 2020-02-12 GLY A:263 A:263 2.0 0.027 H -63.4 -45.6 2.0 0.027 0.0 HOH
 3.437
 HA3
 O
3old 1 P04746 99.8 0.0 X-RAY
 2011-04-13 GLY A:263 A:263 0.0 0.0 H -66.1 -45.1 0.0 0.0 0.0 HOH
 3.923
 CA
 O
3ole 1 P04746 99.8 0.0 X-RAY
 2011-04-13 GLY A:263 A:263 1.0 0.013 H -65.1 -44.0 1.0 0.013 0.0 HOH
 3.937
 CA
 O
3olg 1 P04746 99.8 0.0 X-RAY
 2011-04-13 GLY A:263 A:263 0.0 0.0 H -54.2 -44.8 0.0 0.0 0.0 HOH
 3.842
 CA
 O
3oli 1 P04746 99.8 0.0 X-RAY
 2011-04-13 GLY A:263 A:263 0.0 0.0 H -62.6 -44.0 0.0 0.0 0.0 HOH
 3.958
 CA
 O
1kgw 1 P04746 99.6 0.0 X-RAY
 2002-01-16 GLY A:263 A:263 1.0 0.013 H -64.1 -44.0 1.0 0.013 0.0 HOH
 4.064
 CA
 O
1xgz 1 P04746 99.6 0.0 X-RAY
 2005-05-24 GLY A:263 A:263 2.0 0.027 H -65.4 -43.2 2.0 0.027 0.0 HOH
 4.036
 CA
 O
1xh0 1 P04746 99.6 0.0 X-RAY
 2005-05-24 GLY A:263 A:263 2.0 0.027 H -64.2 -43.2 2.0 0.027 0.0 HOH
 4.192
 CA
 O
1xh1 1 P04746 99.6 0.0 X-RAY
 2005-05-24 GLY A:263 A:263 2.0 0.027 H -63.6 -49.7 2.0 0.027 0.0 HOH
 4.058
 CA
 O
1xh2 1 P04746 99.6 0.0 X-RAY
 2005-05-24 GLY A:263 A:263 1.0 0.013 H -61.9 -47.6 1.0 0.013 0.0 HOH
 3.942
 CA
 O
3bak 1 P04746 99.6 0.0 X-RAY
 2008-03-25 GLY A:263 A:263 2.0 0.027 H -65.2 -48.7 2.0 0.027 0.0 HOH
 4.091
 CA
 O
3bax 1 P04746 99.6 0.0 X-RAY
 2008-03-25 GLY A:263 A:263 2.0 0.027 H -67.7 -40.8 2.0 0.027 0.0 HOH
 3.952
 CA
 O
3bay 1 P04746 99.6 0.0 X-RAY
 2008-03-25 GLY A:263 A:263 0.0 0.0 H -67.0 -41.6 0.0 0.0 0.0 HOH
 4.038
 CA
 O
1kgx 1 P04746 99.6 0.0 X-RAY
 2002-01-16 GLY A:263 A:263 2.0 0.027 H -67.7 -44.8 2.0 0.027 0.0 HOH
 4.083
 N
 O
6z8l 1 P04746 99.6 0.0 X-RAY
 2020-12-02 GLY A:263 A:263 1.0 0.013 H -62.4 -41.7 1.0 0.013 0.0 HOH
 3.345
 HA3
 O
1kgu 1 P04746 99.6 0.0 X-RAY
 2002-01-16 GLY A:263 A:263 1.0 0.013 H -64.3 -40.2 1.0 0.013 0.0 HOH
 4.080
 CA
 O
2cpu 1 P04746 99.6 0.0 X-RAY
 2001-06-30 GLY A:263 A:263 1.0 0.013 H -65.7 -44.3 1.0 0.013 0.0 HOH
 3.933
 CA
 O
3cpu 1 P04746 99.6 0.0 X-RAY
 2001-06-30 GLY A:263 A:263 1.0 0.013 H -64.7 -43.4 1.0 0.013 0.0 HOH
 4.042
 CA
 O
5td4 1 P04746 99.6 0.0 X-RAY
 2016-11-02 GLY A:263 A:263 1.0 0.013 H -66.7 -37.4 1.0 0.013 0.0 HOH
 3.843
 CA
 O
1kb3 1 P04746 99.6 0.0 X-RAY
 2002-05-01 GLY A:263 A:263 1.0 0.013 H -65.0 -46.7 1.0 0.013 0.0 HOH
 4.153
 CA
 O
1kbb 1 P04746 99.6 0.0 X-RAY
 2002-04-10 GLY A:263 A:263 1.0 0.013 H -65.3 -39.4 1.0 0.013 0.0 HOH
 3.923
 CA
 O
1kbk 1 P04746 99.6 0.0 X-RAY
 2002-04-10 GLY A:263 A:263 2.0 0.027 H -63.1 -49.5 2.0 0.027 0.0 HOH
 4.058
 CA
 O
1c8q 1 P04745 96.98 0.0 X-RAY
 2001-06-13 GLY A:263 A:263 0.0 0.0 H -63.2 -44.9 0.0 0.0 0.0 HOH
 4.009
 CA
 O
1mfv 1 P04745 96.98 0.0 X-RAY
 2002-11-20 GLY A:263 A:263 1.0 0.013 H -56.6 -47.5 1.0 0.013 0.0 HOH
 3.867
 CA
 O
1smd 1 P04745 96.98 0.0 X-RAY
 1996-07-11 GLY A:263 A:263 1.0 0.013 H -65.6 -45.0 1.0 0.013 0.0 HOH
 3.945
 CA
 O
1xv8 1 P04745 96.98 0.0 X-RAY
 2005-10-11 GLY A:263 A:263 1.0 0.013 H -58.6 -44.4 1.0 0.013 0.0 HOH
 3.881
 CA
 O
GLY B:263 B:263 0.0 0.0 H -58.6 -44.4 0.0 0.0 0.0 HOH
 3.881
 CA
 O
1z32 1 P04745 96.77 0.0 X-RAY
 2005-05-31 GLY A:263 X:263 0.0 0.0 H -59.3 -43.8 0.0 0.0 0.0 HOH
 3.876
 CA
 O
1jxj 1 P04745 96.77 0.0 X-RAY
 2001-09-14 GLY A:263 A:263 0.0 0.0 H -62.9 -45.5 0.0 0.0 0.0 HOH
 3.856
 CA
 O
1q4n 1 P04745 96.77 0.0 X-RAY
 2004-03-16 GLY A:263 X:263 2.0 0.027 H -58.1 -45.0 2.0 0.027 0.0 HOH
 3.834
 CA
 O
1nm9 1 P04745 96.77 0.0 X-RAY
 2004-01-20 GLY A:263 A:263 1.0 0.013 H -54.9 -48.1 1.0 0.013 0.0 HOH
 3.874
 CA
 O
3blk 1 P04745 96.77 0.0 X-RAY
 2008-11-25 GLY A:263 A:263 2.0 0.027 H -58.6 -41.4 2.0 0.027 0.0 HOH
 4.050
 N
 O
3blp 1 P04745 96.77 0.0 X-RAY
 2008-11-18 GLY A:263 X:263 0.0 0.0 H -58.8 -43.7 0.0 0.0 0.0 HOH
 3.986
 N
 O
1jxk 1 P04745 95.97 0.0 X-RAY
 2001-09-14 GLY A:263 A:263 0.0 0.0 H -60.3 -48.1 0.0 0.0 0.0 HOH
 3.800
 CA
 O
1mfu 1 P04745 95.97 0.0 X-RAY
 2002-11-20 GLY A:263 A:263 0.0 0.0 H -60.1 -46.1 0.0 0.0 0.0 HOH
 3.726
 CA
 O
3dhp 1 P04745 95.77 0.0 X-RAY
 2008-07-01 GLY A:263 A:263 0.0 0.0 H -55.7 -45.5 0.0 0.0 0.0 HOH
 3.968
 N
 O
1kxq 1 P00690 86.9 0.0 X-RAY
 2002-06-19 GLY A:263 A:263 0.0 0.0 H -60.4 -45.2 0.0 0.0 0.0 HOH
 3.723
 CA
 O
GLY B:263 B:263 0.0 0.0 H -64.2 -45.1 NA NA NA
GLY C:263 C:263 1.0 0.013 H -66.3 -41.7 NA NA NA
GLY D:263 D:263 1.0 0.013 H -62.3 -42.9 NA NA NA
1kxt 1 P00690 86.9 0.0 X-RAY
 2002-06-19 GLY A:263 A:263 2.0 0.027 H -59.9 -43.9 2.0 0.027 0.0 HOH
 3.847
 CA
 O
GLY C:263 C:263 1.0 0.013 H -54.4 -41.6 NA NA NA
GLY E:263 E:263 1.0 0.013 H -63.3 -46.6 NA NA NA
1kxv 1 P00690 86.9 0.0 X-RAY
 2002-06-19 GLY A:263 A:263 1.0 0.013 H -63.7 -40.9 1.0 0.013 0.0 HOH
 3.793
 CA
 O
GLY B:263 B:263 1.0 0.013 H -66.5 -43.3 NA NA NA
1dhk 1 P00690 86.9 0.0 X-RAY
 1997-12-24 GLY A:263 A:263 1.0 0.013 H -60.3 -40.7 1.0 0.013 0.0 HOH
 3.544
 CA
 H1
1ppi 1 P00690 86.9 0.0 X-RAY
 1995-05-24 GLY A:263 A:263 1.0 0.013 H -53.1 -52.4 1.0 0.013 0.0 HOH
 4.009
 CA
 O
1vah 1 P00690 86.69 0.0 X-RAY
 2005-04-26 GLY A:263 A:263 1.0 0.013 H -57.8 -42.0 1.0 0.013 0.0 HOH
 3.872
 CA
 O
3l2l 1 P00690 86.69 0.0 X-RAY
 2010-04-14 GLY A:263 A:263 1.0 0.013 H -65.2 -42.5 1.0 0.013 0.0 HOH
 3.421
 HA3
 O
3l2m 1 P00690 86.69 0.0 X-RAY
 2010-04-14 GLY A:263 A:263 2.0 0.027 H -59.4 -47.4 2.0 0.027 0.0 HOH
 3.368
 HA3
 O
1ua3 1 P00690 86.69 0.0 X-RAY
 2003-10-14 GLY A:263 A:263 0.0 0.0 H -57.3 -45.4 0.0 0.0 0.0 HOH
 3.805
 CA
 O
1jfh 1 P00690 86.69 0.0 X-RAY
 1998-12-02 GLY A:263 A:263 1.0 0.013 H -59.2 -44.7 1.0 0.013 0.0 HOH
 3.966
 CA
 O
1ose 1 P00690 86.49 0.0 X-RAY
 1997-04-01 GLY A:263 A:263 0.0 0.0 H -59.5 -40.7 0.0 0.0 0.0 HOH
 3.766
 CA
 O
1hx0 1 P00690 86.49 0.0 X-RAY
 2001-08-08 GLY A:263 A:263 1.0 0.013 H -57.4 -48.0 1.0 0.013 0.0 EDO
HOH
 8.669
3.882
 CA
CA
 O1
O
1wo2 1 P00690 86.49 0.0 X-RAY
 2005-03-15 GLY A:263 A:263 0.0 0.0 H -62.9 -42.8 0.0 0.0 0.0 HOH
 3.811
 CA
 O
1bvn 1 P00690 86.49 0.0 X-RAY
 1998-09-23 GLY A:263 P:263 2.0 0.027 H -76.1 -21.6 2.0 0.027 0.0 HOH
 4.091
 CA
 O
1pif 1 P00690 86.29 0.0 X-RAY
 1996-12-07 GLY A:263 A:263 0.0 0.0 H -61.5 -47.2 0.0 0.0 0.0 HOH
 3.839
 CA
 O
1pig 1 P00690 86.29 0.0 X-RAY
 1996-12-07 GLY A:263 A:263 1.0 0.013 H -62.9 -47.3 1.0 0.013 0.0 HOH
 3.872
 CA
 O
4x0n 1 P00690 86.29 0.0 X-RAY
 2015-11-25 GLY A:263 A:263 0.0 0.0 H -57.9 -47.8 0.0 0.0 0.0 HOH
 4.003
 CA
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04746-f1 1 P04746 100.0 0.0 GLY A:278 A:278 1.0 0.013 H -59.3 -50.2
af-p19961-f1 1 P19961 98.83 0.0 GLY A:278 A:278 0.0 0.0 H -58.0 -51.5
af-p0dte7-f1 1 P0DTE7 96.87 0.0 GLY A:278 A:278 0.0 0.0 H -58.1 -51.1
af-p0dte8-f1 1 P0DTE8 96.87 0.0 GLY A:278 A:278 1.0 0.013 H -58.1 -51.4
af-p0dub6-f1 1 P0DUB6 96.87 0.0 GLY A:278 A:278 0.0 0.0 H -58.1 -51.9