Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 104166754 . G A CCDS783.1:NM_000699.2:c.1257caG>caA_NP_000690.1:p.419Q>Q Homo sapiens amylase, alpha 2A (pancreatic) (AMY2A), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1b2y 1 P04746 100.0 0.0 X-RAY
 2000-02-16 GLN A:404 A:404 55.0 0.306 -78.7 142.7 55.0 0.306 0.0 HOH
 4.289
 O
 O
1bsi 1 P04746 99.8 0.0 X-RAY
 1999-05-18 GLN A:404 A:404 55.0 0.306 -74.6 142.8 55.0 0.306 0.0 HOH
 3.629
 NE2
 O
1cpu 1 P04746 99.8 0.0 X-RAY
 1999-06-14 GLN A:404 A:404 55.0 0.306 -75.0 142.8 55.0 0.306 0.0 HOH
 3.736
 C
 O
1hny 1 P04746 99.8 0.0 X-RAY
 1996-03-08 GLN A:404 A:404 56.0 0.311 -79.1 141.9 56.0 0.311 0.0 HOH
 3.238
 OE1
 O
1u2y 1 P04746 99.8 0.0 X-RAY
 2004-09-07 GLN A:404 A:404 54.0 0.3 -71.2 141.3 54.0 0.3 0.0 HOH
 3.236
 OE1
 O
1u30 1 P04746 99.8 0.0 X-RAY
 2004-09-07 GLN A:404 A:404 49.0 0.272 -74.4 140.4 49.0 0.272 0.0 HOH
 4.203
 O
 O
1u33 1 P04746 99.8 0.0 X-RAY
 2004-09-07 GLN A:404 A:404 57.0 0.317 -72.2 143.0 57.0 0.317 0.0 HOH
 4.422
 N
 O
1xcw 1 P04746 99.8 0.0 X-RAY
 2004-12-07 GLN A:404 A:404 57.0 0.317 -75.9 143.5 57.0 0.317 0.0 HOH
 3.719
 C
 O
1xcx 1 P04746 99.8 0.0 X-RAY
 2004-12-07 GLN A:404 A:404 53.0 0.294 -71.0 143.9 53.0 0.294 0.0 HOH
 6.104
 N
 O
1xd0 1 P04746 99.8 0.0 X-RAY
 2004-12-07 GLN A:404 A:404 51.0 0.283 -75.2 140.9 51.0 0.283 0.0 HOH
 5.065
 O
 O
1xd1 1 P04746 99.8 0.0 X-RAY
 2004-12-07 GLN A:404 A:404 56.0 0.311 -65.1 140.8 56.0 0.311 0.0 HOH
 4.505
 N
 O
2qmk 1 P04746 99.8 0.0 X-RAY
 2008-03-25 GLN A:404 A:404 50.0 0.278 -62.6 140.9 50.0 0.278 0.0 HOH
 3.115
 NE2
 O
2qv4 1 P04746 99.8 0.0 X-RAY
 2008-03-25 GLN A:404 A:404 49.0 0.272 -74.9 136.1 49.0 0.272 0.0 HOH
 4.043
 C
 O
3bai 1 P04746 99.8 0.0 X-RAY
 2008-03-25 GLN A:404 A:404 50.0 0.278 -75.4 137.1 50.0 0.278 0.0 HOH
 3.096
 NE2
 O
3baj 1 P04746 99.8 0.0 X-RAY
 2008-03-25 GLN A:404 A:404 48.0 0.267 -71.5 137.6 48.0 0.267 0.0 HOH
 3.143
 OE1
 O
3baw 1 P04746 99.8 0.0 X-RAY
 2008-03-25 GLN A:404 A:404 53.0 0.294 -78.3 141.4 53.0 0.294 0.0 HOH
 2.975
 O
 O
3ij7 1 P04746 99.8 0.0 X-RAY
 2009-10-27 GLN A:404 A:404 56.0 0.311 -76.1 142.5 56.0 0.311 0.0 HOH
 2.853
 NE2
 O
3ij8 1 P04746 99.8 0.0 X-RAY
 2009-10-27 GLN A:404 A:404 52.0 0.289 -72.1 142.5 52.0 0.289 0.0 HOH
 3.754
 NE2
 O
3ij9 1 P04746 99.8 0.0 X-RAY
 2009-10-27 GLN A:404 A:404 54.0 0.3 -71.2 143.4 54.0 0.3 0.0 HOH
 4.375
 N
 O
4gqq 1 P04746 99.8 0.0 X-RAY
 2012-10-24 GLN A:404 A:404 50.0 0.278 -86.9 141.9 50.0 0.278 0.0 HOH
 3.734
 OE1
 O
4gqr 1 P04746 99.8 0.0 X-RAY
 2012-10-24 GLN A:404 A:404 52.0 0.289 -74.8 137.2 52.0 0.289 0.0 HOH
 2.649
 OE1
 O
4w93 1 P04746 99.8 0.0 X-RAY
 2015-07-15 GLN A:404 A:404 57.0 0.317 -74.8 142.8 57.0 0.317 0.0 HOH
 2.817
 NE2
 O
4x9y 1 P04746 99.8 0.0 X-RAY
 2014-12-31 GLN A:404 A:404 57.0 0.317 -81.8 146.9 57.0 0.317 0.0 HOH
 2.250
 HE21
 O
5e0f 1 P04746 99.8 0.0 X-RAY
 2016-09-07 GLN A:404 A:404 59.0 0.328 -83.0 144.8 59.0 0.328 0.0 HOH
 2.998
 O
 O
5emy 1 P04746 99.8 0.0 X-RAY
 2016-07-06 GLN A:404 A:404 58.0 0.322 -83.9 145.6 58.0 0.322 0.0 HOH
 2.186
 HE21
 O
5kez 1 P04746 99.8 0.0 X-RAY
 2017-03-29 GLN A:404 A:404 58.0 0.322 -85.1 146.6 58.0 0.322 0.0 HOH
 4.179
 NE2
 O
5u3a 1 P04746 99.8 0.0 X-RAY
 2017-12-06 GLN A:404 A:404 56.0 0.311 -83.0 147.0 56.0 0.311 0.0 HOH
 2.060
 HE21
 O
5va9 1 P04746 99.8 0.0 X-RAY
 2018-03-28 GLN A:404 A:404 60.0 0.333 -82.1 140.3 60.0 0.333 0.0 HOH
 4.184
 CG
 O
GLN B:404 B:404 61.0 0.339 -81.6 140.2 NA NA NA
6obx 1 P04746 99.8 0.0 X-RAY
 2020-02-12 GLN A:404 A:404 57.0 0.317 -83.7 146.0 57.0 0.317 0.0 HOH
 2.154
 HE21
 O
6ocn 1 P04746 99.8 0.0 X-RAY
 2020-02-12 GLN A:404 A:404 57.0 0.317 -83.3 146.3 57.0 0.317 0.0 HOH
 2.061
 HE21
 O
3old 1 P04746 99.8 0.0 X-RAY
 2011-04-13 GLN A:404 A:404 55.0 0.306 -76.0 144.6 55.0 0.306 0.0 HOH
 4.630
 N
 O
3ole 1 P04746 99.8 0.0 X-RAY
 2011-04-13 GLN A:404 A:404 55.0 0.306 -74.0 144.3 55.0 0.306 0.0 HOH
 2.775
 OE1
 O
3olg 1 P04746 99.8 0.0 X-RAY
 2011-04-13 GLN A:404 A:404 53.0 0.294 -73.6 145.0 53.0 0.294 0.0 HOH
 3.877
 NE2
 O
3oli 1 P04746 99.8 0.0 X-RAY
 2011-04-13 GLN A:404 A:404 53.0 0.294 -74.5 140.9 53.0 0.294 0.0 HOH
 2.498
 NE2
 O
1kgw 1 P04746 99.6 0.0 X-RAY
 2002-01-16 GLN A:404 A:404 55.0 0.306 -78.2 143.3 55.0 0.306 0.0 HOH
 3.880
 NE2
 O
1xgz 1 P04746 99.6 0.0 X-RAY
 2005-05-24 GLN A:404 A:404 55.0 0.306 -74.4 140.2 55.0 0.306 0.0 HOH
 3.178
 NE2
 O
1xh0 1 P04746 99.6 0.0 X-RAY
 2005-05-24 GLN A:404 A:404 55.0 0.306 -68.5 141.0 55.0 0.306 0.0 HOH
 2.582
 NE2
 O
1xh1 1 P04746 99.6 0.0 X-RAY
 2005-05-24 GLN A:404 A:404 52.0 0.289 -72.4 140.0 52.0 0.289 0.0 HOH
 2.935
 NE2
 O
1xh2 1 P04746 99.6 0.0 X-RAY
 2005-05-24 GLN A:404 A:404 54.0 0.3 -71.7 142.0 54.0 0.3 0.0 HOH
 3.127
 OE1
 O
3bak 1 P04746 99.6 0.0 X-RAY
 2008-03-25 GLN A:404 A:404 47.0 0.261 -77.8 139.6 47.0 0.261 0.0 HOH
 4.344
 N
 O
3bax 1 P04746 99.6 0.0 X-RAY
 2008-03-25 GLN A:404 A:404 53.0 0.294 -76.0 139.9 53.0 0.294 0.0 HOH
 2.750
 OE1
 O
3bay 1 P04746 99.6 0.0 X-RAY
 2008-03-25 GLN A:404 A:404 48.0 0.267 -69.9 137.9 48.0 0.267 0.0 HOH
 3.181
 NE2
 O
1kgx 1 P04746 99.6 0.0 X-RAY
 2002-01-16 GLN A:404 A:404 53.0 0.294 -75.5 141.0 53.0 0.294 0.0 HOH
 3.536
 NE2
 O
6z8l 1 P04746 99.6 0.0 X-RAY
 2020-12-02 GLN A:404 A:404 58.0 0.322 -85.0 145.8 58.0 0.322 0.0 HOH
 2.907
 HG2
 O
1kgu 1 P04746 99.6 0.0 X-RAY
 2002-01-16 GLN A:404 A:404 58.0 0.322 -69.1 145.8 58.0 0.322 0.0 HOH
 3.498
 NE2
 O
2cpu 1 P04746 99.6 0.0 X-RAY
 2001-06-30 GLN A:404 A:404 57.0 0.317 -77.3 141.2 57.0 0.317 0.0 HOH
 3.133
 O
 O
3cpu 1 P04746 99.6 0.0 X-RAY
 2001-06-30 GLN A:404 A:404 60.0 0.333 -83.8 141.8 60.0 0.333 0.0 HOH
 3.461
 O
 O
5td4 1 P04746 99.6 0.0 X-RAY
 2016-11-02 GLN A:404 A:404 54.0 0.3 -83.1 144.3 54.0 0.3 0.0 HOH
 3.704
 CG
 O
1kb3 1 P04746 99.6 0.0 X-RAY
 2002-05-01 GLN A:404 A:404 55.0 0.306 -69.7 142.9 55.0 0.306 0.0 HOH
 4.184
 O
 O
1kbb 1 P04746 99.6 0.0 X-RAY
 2002-04-10 GLN A:404 A:404 58.0 0.322 -76.3 146.6 58.0 0.322 0.0 HOH
 7.956
 CB
 O
1kbk 1 P04746 99.6 0.0 X-RAY
 2002-04-10 GLN A:404 A:404 53.0 0.294 -74.4 140.3 53.0 0.294 0.0
1c8q 1 P04745 96.98 0.0 X-RAY
 2001-06-13 GLN A:404 A:404 55.0 0.306 -70.0 144.0 55.0 0.306 0.0 HOH
 3.911
 O
 O
1mfv 1 P04745 96.98 0.0 X-RAY
 2002-11-20 GLN A:404 A:404 55.0 0.306 -81.7 142.6 55.0 0.306 0.0 HOH
 3.662
 CG
 O
1smd 1 P04745 96.98 0.0 X-RAY
 1996-07-11 GLN A:404 A:404 55.0 0.306 -76.1 147.8 55.0 0.306 0.0 HOH
 5.683
 O
 O
1xv8 1 P04745 96.98 0.0 X-RAY
 2005-10-11 GLN A:404 A:404 56.0 0.311 -76.8 139.7 56.0 0.311 0.0 HOH
 2.998
 NE2
 O
GLN B:404 B:404 55.0 0.306 -76.8 139.8 55.0 0.306 0.0 HOH
 2.998
 NE2
 O
1z32 1 P04745 96.77 0.0 X-RAY
 2005-05-31 GLN A:404 X:404 57.0 0.317 -81.8 143.3 57.0 0.317 0.0 HOH
 3.658
 CG
 O
1jxj 1 P04745 96.77 0.0 X-RAY
 2001-09-14 GLN A:404 A:404 56.0 0.311 -77.3 146.1 56.0 0.311 0.0 HOH
 4.077
 CG
 O
1q4n 1 P04745 96.77 0.0 X-RAY
 2004-03-16 GLN A:404 X:404 54.0 0.3 -83.1 143.8 54.0 0.3 0.0 HOH
 3.870
 NE2
 O
1nm9 1 P04745 96.77 0.0 X-RAY
 2004-01-20 GLN A:404 A:404 56.0 0.311 -82.2 141.7 56.0 0.311 0.0 HOH
 2.795
 OE1
 O
3blk 1 P04745 96.77 0.0 X-RAY
 2008-11-25 GLN A:404 A:404 52.0 0.289 -86.0 140.6 52.0 0.289 0.0 HOH
 3.562
 NE2
 O
3blp 1 P04745 96.77 0.0 X-RAY
 2008-11-18 GLN A:404 X:404 54.0 0.3 -81.9 140.8 54.0 0.3 0.0 HOH
 3.186
 OE1
 O
1jxk 1 P04745 95.97 0.0 X-RAY
 2001-09-14 GLN A:399 A:399 56.0 0.311 -82.1 142.2 56.0 0.311 0.0 HOH
 4.171
 N
 O
1mfu 1 P04745 95.97 0.0 X-RAY
 2002-11-20 GLN A:399 A:399 56.0 0.311 -83.0 141.9 56.0 0.311 0.0 HOH
 2.892
 NE2
 O
3dhp 1 P04745 95.77 0.0 X-RAY
 2008-07-01 GLN A:404 A:404 55.0 0.306 -82.6 144.5 55.0 0.306 0.0 HOH
 2.706
 OE1
 O
1kxq 1 P00690 86.9 0.0 X-RAY
 2002-06-19 GLN A:404 A:404 51.0 0.283 -84.6 142.4 51.0 0.283 0.0 HOH
 2.650
 OE1
 O
GLN B:404 B:404 53.0 0.294 -78.3 139.5 NA NA NA
GLN C:404 C:404 54.0 0.3 -79.5 138.3 NA NA NA
GLN D:404 D:404 54.0 0.3 -84.0 141.5 NA NA NA
1kxt 1 P00690 86.9 0.0 X-RAY
 2002-06-19 GLN A:404 A:404 52.0 0.289 -82.5 139.2 52.0 0.289 0.0 HOH
 3.403
 O
 O
GLN C:404 C:404 54.0 0.3 -72.4 137.8 NA NA NA
GLN E:404 E:404 50.0 0.278 -69.3 132.8 NA NA NA
1kxv 1 P00690 86.9 0.0 X-RAY
 2002-06-19 GLN A:404 A:404 58.0 0.322 -68.8 137.1 58.0 0.322 0.0 HOH
 2.921
 OE1
 O
GLN B:404 B:404 59.0 0.328 -66.6 141.0 NA NA NA
1dhk 1 P00690 86.9 0.0 X-RAY
 1997-12-24 GLN A:404 A:404 55.0 0.306 -69.9 135.9 55.0 0.306 0.0 HOH
 3.668
 O
 H1
1ppi 1 P00690 86.9 0.0 X-RAY
 1995-05-24 GLU A:404 A:404 56.0 0.295 -96.8 143.0 56.0 0.295 0.0 HOH
 2.918
 OE2
 O
1vah 1 P00690 86.69 0.0 X-RAY
 2005-04-26 GLU A:404 A:404 52.0 0.274 -78.5 143.0 52.0 0.274 0.0 HOH
 4.575
 O
 O
3l2l 1 P00690 86.69 0.0 X-RAY
 2010-04-14 GLN A:404 A:404 55.0 0.306 -90.8 139.6 55.0 0.306 0.0 HOH
 2.530
 HE22
 O
3l2m 1 P00690 86.69 0.0 X-RAY
 2010-04-14 GLN A:404 A:404 56.0 0.311 -82.4 137.4 56.0 0.311 0.0 HOH
 2.360
 HE22
 O
1ua3 1 P00690 86.69 0.0 X-RAY
 2003-10-14 GLN A:404 A:404 54.0 0.3 -84.9 139.5 54.0 0.3 0.0 HOH
 2.602
 OE1
 O
1jfh 1 P00690 86.69 0.0 X-RAY
 1998-12-02 GLU A:404 A:404 55.0 0.289 -82.7 142.8 55.0 0.289 0.0 HOH
 3.112
 OE2
 O
1ose 1 P00690 86.49 0.0 X-RAY
 1997-04-01 GLU A:404 A:404 54.0 0.284 -80.7 138.4 54.0 0.284 0.0 HOH
 2.948
 OE2
 O
1hx0 1 P00690 86.49 0.0 X-RAY
 2001-08-08 GLN A:404 A:404 55.0 0.306 -87.4 139.7 55.0 0.306 0.0 HOH
 2.641
 OE1
 O
1wo2 1 P00690 86.49 0.0 X-RAY
 2005-03-15 GLN A:404 A:404 53.0 0.294 -81.2 138.8 53.0 0.294 0.0 HOH
 2.811
 OE1
 O
1bvn 1 P00690 86.49 0.0 X-RAY
 1998-09-23 GLN A:404 P:404 55.0 0.306 -77.8 148.5 55.0 0.306 0.0 HOH
 3.431
 NE2
 O
1pif 1 P00690 86.29 0.0 X-RAY
 1996-12-07 GLN A:404 A:404 60.0 0.333 -75.8 139.4 60.0 0.333 0.0 HOH
 4.260
 NE2
 O
1pig 1 P00690 86.29 0.0 X-RAY
 1996-12-07 GLN A:404 A:404 55.0 0.306 -69.2 136.3 55.0 0.306 0.0 HOH
 5.056
 O
 O
4x0n 1 P00690 86.29 0.0 X-RAY
 2015-11-25 GLN A:404 A:404 54.0 0.3 -85.8 140.1 54.0 0.3 0.0 HOH
 4.361
 N
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04746-f1 1 P04746 100.0 0.0 GLN A:419 A:419 55.0 0.306 -80.5 142.7
af-p19961-f1 1 P19961 98.83 0.0 GLN A:419 A:419 57.0 0.317 -79.1 143.4
af-p0dte7-f1 1 P0DTE7 96.87 0.0 GLN A:419 A:419 57.0 0.317 -79.1 143.7
af-p0dte8-f1 1 P0DTE8 96.87 0.0 GLN A:419 A:419 56.0 0.311 -78.6 143.4
af-p0dub6-f1 1 P0DUB6 96.87 0.0 GLN A:419 A:419 58.0 0.322 -77.3 142.9