Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 104203055 . C A CCDS30782.1:NM_001008221.1:c.952Cga>Aga_NP_001008222.1:p.318R>R Homo sapiens amylase, alpha 1A (salivary) (AMY1A), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1c8q 1 P04745 99.8 0.0 X-RAY
 2001-06-13 ARG A:303 A:303 14.0 0.062 G -116.7 -6.1 14.0 0.062 0.0 HOH
 2.622
 O
 O
1mfv 1 P04745 99.8 0.0 X-RAY
 2002-11-20 ARG A:303 A:303 9.0 0.04 G -124.0 23.2 9.0 0.04 0.0 GLC
AGL
AGL
HMC
HOH
 7.222
9.820
9.171
7.632
2.908
 CD
CD
CG
CD
NH2
 O2
O2
C6
O3
O
1smd 1 P04745 99.8 0.0 X-RAY
 1996-07-11 ARG A:303 A:303 14.0 0.062 G -106.1 12.2 14.0 0.062 0.0 HOH
 2.549
 O
 O
1xv8 1 P04745 99.8 0.0 X-RAY
 2005-10-11 ARG A:303 A:303 8.0 0.036 G -91.4 11.2 8.0 0.036 0.0 HOH
 8.110
 N
 O
ARG B:303 B:303 8.0 0.036 G -91.4 11.2 8.0 0.036 0.0 HOH
 8.110
 N
 O
1q4n 1 P04745 99.6 0.0 X-RAY
 2004-03-16 ARG A:303 X:303 8.0 0.036 G -121.3 32.1 8.0 0.036 0.0 TAM
HOH
 7.745
2.993
 CD
NE
 O5
O
1z32 1 P04745 99.6 0.0 X-RAY
 2005-05-31 ARG A:303 X:303 9.0 0.04 G -128.5 19.3 9.0 0.04 0.0 GLC
AGL
HMC
HOH
 7.319
9.196
7.877
2.916
 CD
CG
CD
NH2
 O2
C6
O3
O
1jxj 1 P04745 99.6 0.0 X-RAY
 2001-09-14 ARG A:303 A:303 15.0 0.067 G -93.6 -3.6 15.0 0.067 0.0 HOH
 2.567
 O
 O
1nm9 1 P04745 99.6 0.0 X-RAY
 2004-01-20 ARG A:303 A:303 15.0 0.067 G -113.7 22.7 15.0 0.067 0.0 AGL
HMC
HOH
 9.141
7.611
2.815
 CG
CD
NH2
 C6
O3
O
3blk 1 P04745 99.6 0.0 X-RAY
 2008-11-25 ARG A:303 A:303 10.0 0.044 G -126.1 26.4 10.0 0.044 0.0 GLC
AGL
AGL
HMC
HOH
 7.251
9.887
9.310
7.772
2.915
 CD
CD
CG
CD
NH2
 O2
O2
C6
O3
O
3blp 1 P04745 99.6 0.0 X-RAY
 2008-11-18 ARG A:303 X:303 10.0 0.044 G -126.2 21.1 10.0 0.044 0.0 GLC
AGL
AGL
HMC
HOH
 7.163
9.859
9.276
7.652
2.789
 CD
CD
CG
CD
O
 O2
O2
C6
O3
O
1jxk 1 P04745 98.79 0.0 X-RAY
 2001-09-14 ARG A:303 A:303 19.0 0.084 G -93.4 -5.2 19.0 0.084 0.0 HOH
 2.636
 O
 O
1mfu 1 P04745 98.79 0.0 X-RAY
 2002-11-20 ARG A:303 A:303 20.0 0.089 G -99.6 -0.2 20.0 0.089 0.0 GLC
AGL
GLC
AGL
HMC
HOH
 7.451
9.944
9.309
9.432
8.036
2.604
 CD
CD
C
CD
CD
O
 O2
O2
O6
C6
O3
O
3dhp 1 P04745 98.59 0.0 X-RAY
 2008-07-01 ARG A:303 A:303 9.0 0.04 G -123.9 20.5 9.0 0.04 0.0 AGL
GLC
HMC
HOH
 9.357
7.119
7.690
2.744
 CG
CD
CD
O
 C6
O2
O3
O
3old 1 P04746 97.38 0.0 X-RAY
 2011-04-13 ARG A:303 A:303 8.0 0.036 G -126.5 25.0 8.0 0.036 0.0 GLC
G6D
ACI
MPD
HOH
 7.272
9.064
7.578
7.073
2.979
 CD
CG
CD
O
NH2
 O2
C6
O3
O4
O
3ole 1 P04746 97.38 0.0 X-RAY
 2011-04-13 ARG A:303 A:303 8.0 0.036 G -127.1 23.2 8.0 0.036 0.0 GLC
G6D
ACI
MPD
HOH
 7.320
9.115
7.683
7.188
2.837
 CD
CG
CD
O
O
 O2
C6
O3
O4
O
3olg 1 P04746 97.38 0.0 X-RAY
 2011-04-13 ARG A:303 A:303 7.0 0.031 G -124.8 24.1 7.0 0.031 0.0 GLC
G6D
G6D
HSD
HOH
 7.201
9.581
9.157
7.745
2.748
 CD
CD
CG
CD
O
 O2
O2
C6
O3
O
3oli 1 P04746 97.38 0.0 X-RAY
 2011-04-13 ARG A:303 A:303 7.0 0.031 G -124.1 24.6 7.0 0.031 0.0 GLC
G6D
G6D
HSD
HOH
 7.221
9.636
9.158
7.637
2.747
 CD
CD
CG
CD
O
 O2
O2
C6
O3
O
6z8l 1 P04746 97.18 0.0 X-RAY
 2020-12-02 ARG A:303 A:303 10.0 0.044 G -127.4 23.3 10.0 0.044 0.0 GLC
GLC
GLC
HOH
 6.438
9.216
8.912
2.176
 HD3
HD3
HG3
HH21
 H2
HO2
H62
O
1b2y 1 P04746 97.18 0.0 X-RAY
 2000-02-16 ARG A:303 A:303 13.0 0.058 T -119.2 -14.7 13.0 0.058 0.0 AC1
GLC
HOH
 8.403
7.605
2.704
 CD
CD
NE
 O3B
O2
O
1bsi 1 P04746 96.98 0.0 X-RAY
 1999-05-18 ARG A:303 A:303 8.0 0.036 G -117.1 31.1 8.0 0.036 0.0 HOH
 3.013
 NH2
 O
1cpu 1 P04746 96.98 0.0 X-RAY
 1999-06-14 ARG A:303 A:303 10.0 0.044 G -130.1 25.9 10.0 0.044 0.0 AGL
GLC
HMC
HOH
 9.209
7.214
7.744
2.945
 CG
CD
CD
O
 C6
O2
O3
O
1hny 1 P04746 96.98 0.0 X-RAY
 1996-03-08 ARG A:303 A:303 9.0 0.04 G -98.8 8.9 9.0 0.04 0.0 HOH
 2.951
 O
 O
1u2y 1 P04746 96.98 0.0 X-RAY
 2004-09-07 ARG A:303 A:303 11.0 0.049 G -125.0 24.8 11.0 0.049 0.0 GOX
HOH
 9.239
2.855
 CD
O
 O7
O
1u30 1 P04746 96.98 0.0 X-RAY
 2004-09-07 ARG A:303 A:303 10.0 0.044 G -128.1 19.3 10.0 0.044 0.0 LAG
HOH
 7.365
2.860
 CD
O
 OB2
O
1u33 1 P04746 96.98 0.0 X-RAY
 2004-09-07 ARG A:303 A:303 10.0 0.044 G -126.7 24.4 10.0 0.044 0.0 LM2
HOH
 6.825
2.892
 CD
O
 OB2
O
1xcw 1 P04746 96.98 0.0 X-RAY
 2004-12-07 ARG A:303 A:303 12.0 0.053 G -117.3 22.2 12.0 0.053 0.0 GLC
AC1
HOH
 9.671
7.853
3.039
 O
CD
NH2
 O6
O3B
O
1xcx 1 P04746 96.98 0.0 X-RAY
 2004-12-07 ARG A:303 A:303 12.0 0.053 G -123.0 25.0 12.0 0.053 0.0 AC1
HOH
 7.857
3.046
 CD
NH2
 O3B
O
1xd0 1 P04746 96.98 0.0 X-RAY
 2004-12-07 ARG A:303 A:303 8.0 0.036 G -126.4 26.4 8.0 0.036 0.0 ARE
HOH
 7.242
3.030
 CD
NH2
 O2B
O
1xd1 1 P04746 96.98 0.0 X-RAY
 2004-12-07 ARG A:303 A:303 7.0 0.031 G -131.8 51.6 7.0 0.031 0.0 6SA
HOH
 7.073
3.011
 CD
NH2
 OU2
O
2qmk 1 P04746 96.98 0.0 X-RAY
 2008-03-25 ARG A:303 A:303 11.0 0.049 T -114.8 -3.9 11.0 0.049 0.0 HOH
 2.773
 NH2
 O
2qv4 1 P04746 96.98 0.0 X-RAY
 2008-03-25 ARG A:303 A:303 12.0 0.053 G -110.0 1.8 12.0 0.053 0.0 QV4
HOH
 7.488
2.877
 CD
NH2
 O2B
O
3bai 1 P04746 96.98 0.0 X-RAY
 2008-03-25 ARG A:303 A:303 9.0 0.04 G -119.8 30.7 9.0 0.04 0.0 HOH
 2.961
 NE
 O
3baj 1 P04746 96.98 0.0 X-RAY
 2008-03-25 ARG A:303 A:303 12.0 0.053 G -126.0 26.7 12.0 0.053 0.0 ARE
HOH
 7.068
3.040
 CD
NH2
 O2B
O
3baw 1 P04746 96.98 0.0 X-RAY
 2008-03-25 ARG A:303 A:303 10.0 0.044 G -113.3 30.5 10.0 0.044 0.0 HOH
 2.889
 NH2
 O
3ij7 1 P04746 96.98 0.0 X-RAY
 2009-10-27 ARG A:303 A:303 7.0 0.031 G -126.1 32.5 7.0 0.031 0.0 B9D
BGC
HOH
 7.803
7.260
2.899
 CD
CD
NH2
 O3
O2
O
3ij8 1 P04746 96.98 0.0 X-RAY
 2009-10-27 ARG A:303 A:303 8.0 0.036 G -123.7 30.1 8.0 0.036 0.0 B0D
B9D
HOH
 9.184
7.840
2.714
 O
CD
O
 O6
O3
O
3ij9 1 P04746 96.98 0.0 X-RAY
 2009-10-27 ARG A:303 A:303 9.0 0.04 G -126.4 32.9 9.0 0.04 0.0 B9D
BGC
HOH
 7.898
7.317
2.930
 CD
CD
NH2
 O3
O2
O
4gqq 1 P04746 96.98 0.0 X-RAY
 2012-10-24 ARG A:303 A:303 36.0 0.16 -94.1 -167.0 36.0 0.16 0.0 HOH
 9.099
 CB
 O
4gqr 1 P04746 96.98 0.0 X-RAY
 2012-10-24 ARG A:303 A:303 6.0 0.027 G -91.7 1.4 6.0 0.027 0.0 HOH
 2.752
 O
 O
4w93 1 P04746 96.98 0.0 X-RAY
 2015-07-15 ARG A:303 A:303 8.0 0.036 G -94.9 3.4 8.0 0.036 0.0 3L9
HOH
 7.185
2.825
 CD
O
 O9F
O
4x9y 1 P04746 96.98 0.0 X-RAY
 2014-12-31 ARG A:303 A:303 10.0 0.044 G -90.9 -4.0 10.0 0.044 0.0 HOH
 2.147
 HH21
 O
5e0f 1 P04746 96.98 0.0 X-RAY
 2016-09-07 ARG A:303 A:303 12.0 0.053 G -92.2 -2.7 12.0 0.053 0.0 5J7
HOH
 6.396
2.077
 HD3
HH21
 O56
O
5emy 1 P04746 96.98 0.0 X-RAY
 2016-07-06 ARG A:303 A:303 10.0 0.044 G -130.3 23.1 10.0 0.044 0.0 5QP
HOH
 6.065
2.120
 HD2
HH22
 HO2
O
5kez 1 P04746 96.98 0.0 X-RAY
 2017-03-29 ARG A:303 A:303 6.0 0.027 G -90.5 8.3 1.0 0.004 0.023 B:None:0.022
 HOH
 2.725
 O
 O
5u3a 1 P04746 96.98 0.0 X-RAY
 2017-12-06 ARG A:303 A:303 11.0 0.049 G -91.5 -1.7 11.0 0.049 0.0 HOH
 2.114
 HH21
 O
5va9 1 P04746 96.98 0.0 X-RAY
 2018-03-28 ARG A:303 A:303 13.0 0.058 G -91.0 -1.5 9.0 0.04 0.018 C:None:0.018
 HOH
 2.638
 O
 O
ARG B:303 B:303 6.0 0.027 G -91.6 -2.6 NA NA NA
6obx 1 P04746 96.98 0.0 X-RAY
 2020-02-12 ARG A:303 A:303 7.0 0.031 G -92.0 1.3 7.0 0.031 0.0 ZXU
HOH
 6.451
2.099
 HD3
HH21
 O45
O
6ocn 1 P04746 96.98 0.0 X-RAY
 2020-02-12 ARG A:303 A:303 8.0 0.036 G -91.0 0.0 8.0 0.036 0.0 ZXY
HOH
 6.758
2.136
 HD3
HH21
 O30
O
1kgw 1 P04746 96.77 0.0 X-RAY
 2002-01-16 ARG A:303 A:303 11.0 0.049 G -125.5 27.2 11.0 0.049 0.0 HOH
 2.773
 NH2
 O
1xgz 1 P04746 96.77 0.0 X-RAY
 2005-05-24 ARG A:303 A:303 15.0 0.067 T -111.0 14.9 15.0 0.067 0.0 HOH
 2.630
 NE
 O
1xh0 1 P04746 96.77 0.0 X-RAY
 2005-05-24 ARG A:303 A:303 10.0 0.044 G -125.3 25.7 10.0 0.044 0.0 AAO
HOH
 7.146
3.004
 CD
NH2
 O2B
O
1xh1 1 P04746 96.77 0.0 X-RAY
 2005-05-24 ARG A:303 A:303 12.0 0.053 G -121.2 22.9 12.0 0.053 0.0 HOH
 2.978
 NH2
 O
1xh2 1 P04746 96.77 0.0 X-RAY
 2005-05-24 ARG A:303 A:303 11.0 0.049 G -127.1 19.8 11.0 0.049 0.0 ARE
HOH
 7.379
3.209
 CD
NH2
 O2B
O
3bak 1 P04746 96.77 0.0 X-RAY
 2008-03-25 ARG A:303 A:303 10.0 0.044 G -120.6 30.0 10.0 0.044 0.0 HOH
 2.911
 NH2
 O
3bax 1 P04746 96.77 0.0 X-RAY
 2008-03-25 ARG A:303 A:303 9.0 0.04 G -122.2 27.6 9.0 0.04 0.0 HOH
 2.934
 NH2
 O
3bay 1 P04746 96.77 0.0 X-RAY
 2008-03-25 ARG A:303 A:303 9.0 0.04 G -120.6 33.4 9.0 0.04 0.0 ARE
HOH
 7.129
3.032
 CD
NH2
 O2B
O
1kgx 1 P04746 96.77 0.0 X-RAY
 2002-01-16 ARG A:303 A:303 12.0 0.053 G -120.5 25.0 12.0 0.053 0.0 HOH
 3.016
 NH2
 O
2cpu 1 P04746 96.77 0.0 X-RAY
 2001-06-30 ARG A:303 A:303 9.0 0.04 T -113.6 18.8 9.0 0.04 0.0 HOH
 2.630
 NH2
 O
3cpu 1 P04746 96.77 0.0 X-RAY
 2001-06-30 ARG A:303 A:303 10.0 0.044 T -124.5 33.5 10.0 0.044 0.0 GLC
HOH
 7.504
2.970
 CD
NH2
 O2
O
5td4 1 P04746 96.77 0.0 X-RAY
 2016-11-02 ARG A:303 A:303 9.0 0.04 G -128.7 26.3 9.0 0.04 0.0 GLC
GLC
GLC
GLC
HOH
 8.767
8.233
7.155
9.657
2.913
 CG
CD
CD
CD
NH2
 O6
O3
O2
O2
O
1kgu 1 P04746 96.77 0.0 X-RAY
 2002-01-16 ARG A:303 A:303 18.0 0.08 T -110.6 -2.8 18.0 0.08 0.0 HOH
 2.767
 NE
 O
1kb3 1 P04746 96.77 0.0 X-RAY
 2002-05-01 ARG A:303 A:303 10.0 0.044 G -118.1 27.7 10.0 0.044 0.0 HOH
 2.979
 NH2
 O
1kbb 1 P04746 96.77 0.0 X-RAY
 2002-04-10 ARG A:303 A:303 10.0 0.044 G -100.9 17.1 10.0 0.044 0.0 HOH
 2.747
 NE
 O
1kbk 1 P04746 96.77 0.0 X-RAY
 2002-04-10 ARG A:303 A:303 9.0 0.04 G -116.8 31.3 9.0 0.04 0.0 HOH
 2.371
 NH2
 O
1kxq 1 P00690 86.29 0.0 X-RAY
 2002-06-19 ARG A:303 A:303 7.0 0.031 G -84.6 -3.8 7.0 0.031 0.0 HOH
 2.785
 O
 O
ARG B:303 B:303 11.0 0.049 G -85.6 -2.8 NA NA NA
ARG C:303 C:303 6.0 0.027 G -87.6 0.9 NA NA NA
ARG D:303 D:303 15.0 0.067 G -88.0 -0.5 NA NA NA
1kxt 1 P00690 86.29 0.0 X-RAY
 2002-06-19 ARG A:303 A:303 5.0 0.022 G -96.4 14.8 5.0 0.022 0.0 HOH
 2.776
 O
 O
ARG C:303 C:303 5.0 0.022 G -98.2 12.7 NA NA NA
ARG E:303 E:303 9.0 0.04 G -107.5 35.5 NA NA NA
1kxv 1 P00690 86.29 0.0 X-RAY
 2002-06-19 ARG A:303 A:303 19.0 0.084 G -89.9 1.6 19.0 0.084 0.0 HOH
 2.682
 O
 O
ARG B:303 B:303 4.0 0.018 G -89.8 3.7 NA NA NA
1dhk 1 P00690 86.29 0.0 X-RAY
 1997-12-24 ARG A:303 A:303 13.0 0.058 S -100.3 168.2 0.0 0.0 0.058 B:P02873:0.058
 CA
HOH
 5.902
1.794
 O
HH22
 CA
H2
1ppi 1 P00690 86.29 0.0 X-RAY
 1995-05-24 ARG A:303 A:303 9.0 0.04 G -124.1 21.8 9.0 0.04 0.0 GLC
GLC
DAF
HOH
 7.353
9.793
7.752
2.806
 CD
CD
CD
NH2
 O2
O2
O3H
O
1vah 1 P00690 86.09 0.0 X-RAY
 2005-04-26 ARG A:303 A:303 6.0 0.027 G -112.3 32.0 6.0 0.027 0.0 NPO
HOH
 8.061
2.645
 CD
NH2
 O3
O
3l2l 1 P00690 86.09 0.0 X-RAY
 2010-04-14 ARG A:303 A:303 9.0 0.04 G -86.3 -0.6 9.0 0.04 0.0 GLC
GLC
GLC
HOH
 7.671
6.675
8.176
2.031
 HD2
HD3
HD3
HE
 HO3
HO3
HO2
O
3l2m 1 P00690 86.09 0.0 X-RAY
 2010-04-14 ARG A:303 A:303 10.0 0.044 G -90.1 -0.7 10.0 0.044 0.0 GLC
GLC
GLC
HOH
 7.862
8.114
5.954
2.042
 HD3
HB2
HD3
HH21
 HO2
HO3
H2
O
1ua3 1 P00690 86.09 0.0 X-RAY
 2003-10-14 ARG A:303 A:303 8.0 0.036 G -98.3 -10.6 8.0 0.036 0.0 GLC
GLC
HOH
 8.481
7.629
2.536
 CD
CD
O
 O3
O2
O
1ose 1 P00690 85.89 0.0 X-RAY
 1997-04-01 ARG A:303 A:303 7.0 0.031 G -127.9 33.1 7.0 0.031 0.0 BGC
AC1
GLC
HOH
 9.444
7.948
7.556
2.846
 O
CD
CD
O
 O6
O3B
O2
O
1jfh 1 P00690 86.09 0.0 X-RAY
 1998-12-02 ARG A:303 A:303 8.0 0.036 G -126.6 24.2 8.0 0.036 0.0 MA3
HOH
 7.319
2.967
 CD
NH2
 O2
O
1hx0 1 P00690 85.89 0.0 X-RAY
 2001-08-08 ARG A:303 A:303 8.0 0.036 G -126.9 22.5 8.0 0.036 0.0 AC1
GLC
EDO
EDO
HOH
 7.735
7.303
4.380
7.556
2.750
 CD
CD
N
NH2
O
 O3B
O2
C2
C2
O
1wo2 1 P00690 85.89 0.0 X-RAY
 2005-03-15 ARG A:303 A:303 5.0 0.022 G -88.5 4.9 5.0 0.022 0.0 BGC
GLC
HOH
 8.378
7.523
2.620
 CD
CD
O
 O3
O2
O
1pif 1 P00690 85.69 0.0 X-RAY
 1996-12-07 ARG A:303 A:303 7.0 0.031 G -89.1 14.1 7.0 0.031 0.0 HOH
 2.548
 NH1
 O
1pig 1 P00690 85.69 0.0 X-RAY
 1996-12-07 ARG A:303 A:303 6.0 0.027 G -128.4 26.1 6.0 0.027 0.0 GLC
AGL
HMC
HOH
 7.190
9.110
7.594
2.860
 CD
CG
CD
NH2
 O2
C6
O3
O
4x0n 1 P00690 85.69 0.0 X-RAY
 2015-11-25 ARG A:303 A:303 4.0 0.018 G -99.2 18.5 4.0 0.018 0.0 GOL
HOH
 3.598
2.968
 CB
NH2
 O1
O
1bvn 1 P00690 85.48 0.0 X-RAY
 1998-09-23 ARG A:303 P:303 7.0 0.031 G -82.6 12.1 7.0 0.031 0.0 HOH
 2.681
 NH2
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p0dte7-f1 1 P0DTE7 100.0 0.0 ARG A:318 A:318 12.0 0.053 G -99.8 3.5
af-p0dte8-f1 1 P0DTE8 100.0 0.0 ARG A:318 A:318 8.0 0.036 G -100.3 9.6
af-p0dub6-f1 1 P0DUB6 100.0 0.0 ARG A:318 A:318 12.0 0.053 G -101.8 4.7
af-p19961-f1 1 P19961 97.46 0.0 ARG A:318 A:318 8.0 0.036 G -95.3 -0.5
af-p04746-f1 1 P04746 96.87 0.0 ARG A:318 A:318 10.0 0.044 G -106.8 3.3