Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 104203222 . T A CCDS30782.1:NM_001008221.1:c.1025tTt>tAt_NP_001008222.1:p.342F>Y Homo sapiens amylase, alpha 1A (salivary) (AMY1A), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1c8q 1 P04745 99.8 0.0 X-RAY
 2001-06-13 PHE A:327 A:327 0.0 0.0 H -62.8 -45.9 0.0 0.0 0.0 HOH
 5.006
 O
 O
1mfv 1 P04745 99.8 0.0 X-RAY
 2002-11-20 PHE A:327 A:327 0.0 0.0 H -52.3 -52.1 0.0 0.0 0.0 HOH
 4.939
 O
 O
1smd 1 P04745 99.8 0.0 X-RAY
 1996-07-11 PHE A:327 A:327 0.0 0.0 H -62.6 -45.0 0.0 0.0 0.0 HOH
 4.925
 O
 O
1xv8 1 P04745 99.8 0.0 X-RAY
 2005-10-11 PHE A:327 A:327 0.0 0.0 H -58.2 -51.6 0.0 0.0 0.0 HOH
 8.817
 CD1
 O
PHE B:327 B:327 0.0 0.0 H -58.1 -51.6 0.0 0.0 0.0 HOH
 8.818
 CD1
 O
1q4n 1 P04745 99.6 0.0 X-RAY
 2004-03-16 PHE A:327 X:327 0.0 0.0 H -60.8 -47.6 0.0 0.0 0.0 HOH
 4.922
 O
 O
1z32 1 P04745 99.6 0.0 X-RAY
 2005-05-31 PHE A:327 X:327 0.0 0.0 H -58.5 -47.1 0.0 0.0 0.0 HOH
 4.891
 O
 O
1jxj 1 P04745 99.6 0.0 X-RAY
 2001-09-14 PHE A:327 A:327 0.0 0.0 H -57.9 -47.0 0.0 0.0 0.0 HOH
 4.838
 O
 O
1nm9 1 P04745 99.6 0.0 X-RAY
 2004-01-20 PHE A:327 A:327 0.0 0.0 H -58.5 -48.0 0.0 0.0 0.0 HOH
 4.853
 O
 O
3blk 1 P04745 99.6 0.0 X-RAY
 2008-11-25 PHE A:327 A:327 0.0 0.0 H -60.6 -49.9 0.0 0.0 0.0 HOH
 4.902
 O
 O
3blp 1 P04745 99.6 0.0 X-RAY
 2008-11-18 PHE A:327 X:327 0.0 0.0 H -63.3 -47.6 0.0 0.0 0.0 HOH
 4.911
 O
 O
1jxk 1 P04745 98.79 0.0 X-RAY
 2001-09-14 PHE A:322 A:322 0.0 0.0 H -63.9 -47.3 0.0 0.0 0.0 HOH
 4.816
 O
 O
1mfu 1 P04745 98.79 0.0 X-RAY
 2002-11-20 PHE A:322 A:322 0.0 0.0 H -57.8 -49.9 0.0 0.0 0.0 HOH
 4.916
 O
 O
3dhp 1 P04745 98.59 0.0 X-RAY
 2008-07-01 PHE A:327 A:327 0.0 0.0 H -61.0 -43.9 0.0 0.0 0.0 HOH
 4.816
 O
 O
3old 1 P04746 97.38 0.0 X-RAY
 2011-04-13 PHE A:327 A:327 0.0 0.0 H -61.5 -47.1 0.0 0.0 0.0 HOH
 4.732
 O
 O
3ole 1 P04746 97.38 0.0 X-RAY
 2011-04-13 PHE A:327 A:327 0.0 0.0 H -62.6 -45.7 0.0 0.0 0.0 HOH
 4.770
 O
 O
3olg 1 P04746 97.38 0.0 X-RAY
 2011-04-13 PHE A:327 A:327 0.0 0.0 H -61.3 -45.7 0.0 0.0 0.0 HOH
 4.904
 O
 O
3oli 1 P04746 97.38 0.0 X-RAY
 2011-04-13 PHE A:327 A:327 0.0 0.0 H -61.4 -46.8 0.0 0.0 0.0 HOH
 4.833
 O
 O
6z8l 1 P04746 97.18 0.0 X-RAY
 2020-12-02 PHE A:327 A:327 0.0 0.0 H -59.3 -47.1 0.0 0.0 0.0 HOH
 4.806
 O
 O
1b2y 1 P04746 97.18 0.0 X-RAY
 2000-02-16 PHE A:327 A:327 0.0 0.0 H -63.6 -44.5 0.0 0.0 0.0 HOH
 6.621
 CZ
 O
1bsi 1 P04746 96.98 0.0 X-RAY
 1999-05-18 PHE A:327 A:327 0.0 0.0 H -64.2 -41.5 0.0 0.0 0.0 HOH
 4.756
 O
 O
1cpu 1 P04746 96.98 0.0 X-RAY
 1999-06-14 PHE A:327 A:327 0.0 0.0 H -63.5 -39.0 0.0 0.0 0.0 HOH
 4.818
 O
 O
1hny 1 P04746 96.98 0.0 X-RAY
 1996-03-08 PHE A:327 A:327 0.0 0.0 H -61.2 -51.0 0.0 0.0 0.0 HOH
 4.980
 O
 O
1u2y 1 P04746 96.98 0.0 X-RAY
 2004-09-07 PHE A:327 A:327 0.0 0.0 H -62.7 -44.9 0.0 0.0 0.0 HOH
 5.681
 N
 O
1u30 1 P04746 96.98 0.0 X-RAY
 2004-09-07 PHE A:327 A:327 0.0 0.0 H -65.2 -45.1 0.0 0.0 0.0 HOH
 4.889
 O
 O
1u33 1 P04746 96.98 0.0 X-RAY
 2004-09-07 PHE A:327 A:327 0.0 0.0 H -59.9 -47.2 0.0 0.0 0.0 HOH
 4.895
 O
 O
1xcw 1 P04746 96.98 0.0 X-RAY
 2004-12-07 PHE A:327 A:327 0.0 0.0 H -62.7 -46.6 0.0 0.0 0.0 HOH
 4.691
 O
 O
1xcx 1 P04746 96.98 0.0 X-RAY
 2004-12-07 PHE A:327 A:327 0.0 0.0 H -61.8 -46.3 0.0 0.0 0.0 HOH
 4.864
 O
 O
1xd0 1 P04746 96.98 0.0 X-RAY
 2004-12-07 PHE A:327 A:327 0.0 0.0 H -62.9 -45.1 0.0 0.0 0.0 HOH
 4.836
 O
 O
1xd1 1 P04746 96.98 0.0 X-RAY
 2004-12-07 PHE A:327 A:327 0.0 0.0 H -61.7 -45.0 0.0 0.0 0.0 HOH
 6.283
 CZ
 O
2qmk 1 P04746 96.98 0.0 X-RAY
 2008-03-25 PHE A:327 A:327 0.0 0.0 H -66.2 -48.7 0.0 0.0 0.0 HOH
 4.709
 O
 O
2qv4 1 P04746 96.98 0.0 X-RAY
 2008-03-25 PHE A:327 A:327 0.0 0.0 H -62.1 -43.5 0.0 0.0 0.0 HOH
 4.708
 O
 O
3bai 1 P04746 96.98 0.0 X-RAY
 2008-03-25 PHE A:327 A:327 0.0 0.0 H -60.7 -44.6 0.0 0.0 0.0 HOH
 4.892
 O
 O
3baj 1 P04746 96.98 0.0 X-RAY
 2008-03-25 PHE A:327 A:327 1.0 0.005 H -59.7 -44.3 1.0 0.005 0.0 HOH
 4.940
 O
 O
3baw 1 P04746 96.98 0.0 X-RAY
 2008-03-25 PHE A:327 A:327 0.0 0.0 H -64.1 -45.6 0.0 0.0 0.0 HOH
 4.823
 O
 O
3ij7 1 P04746 96.98 0.0 X-RAY
 2009-10-27 PHE A:327 A:327 0.0 0.0 H -62.1 -44.1 0.0 0.0 0.0 HOH
 4.738
 O
 O
3ij8 1 P04746 96.98 0.0 X-RAY
 2009-10-27 PHE A:327 A:327 0.0 0.0 H -61.8 -45.0 0.0 0.0 0.0 HOH
 4.854
 O
 O
3ij9 1 P04746 96.98 0.0 X-RAY
 2009-10-27 PHE A:327 A:327 0.0 0.0 H -60.6 -44.1 0.0 0.0 0.0 HOH
 4.780
 O
 O
4gqq 1 P04746 96.98 0.0 X-RAY
 2012-10-24 PHE A:327 A:327 0.0 0.0 H -64.4 -41.7 0.0 0.0 0.0 HOH
 4.813
 O
 O
4gqr 1 P04746 96.98 0.0 X-RAY
 2012-10-24 PHE A:327 A:327 0.0 0.0 H -61.2 -44.9 0.0 0.0 0.0 HOH
 4.768
 O
 O
4w93 1 P04746 96.98 0.0 X-RAY
 2015-07-15 PHE A:327 A:327 0.0 0.0 H -61.0 -45.8 0.0 0.0 0.0 HOH
 4.829
 O
 O
4x9y 1 P04746 96.98 0.0 X-RAY
 2014-12-31 PHE A:327 A:327 0.0 0.0 H -58.7 -48.0 0.0 0.0 0.0 HOH
 4.776
 O
 O
5e0f 1 P04746 96.98 0.0 X-RAY
 2016-09-07 PHE A:327 A:327 0.0 0.0 H -60.6 -46.6 0.0 0.0 0.0 HOH
 4.805
 O
 O
5emy 1 P04746 96.98 0.0 X-RAY
 2016-07-06 PHE A:327 A:327 0.0 0.0 H -58.6 -48.3 0.0 0.0 0.0 HOH
 4.769
 O
 O
5kez 1 P04746 96.98 0.0 X-RAY
 2017-03-29 PHE A:327 A:327 0.0 0.0 H -61.5 -46.3 0.0 0.0 0.0 HOH
 4.880
 O
 O
5u3a 1 P04746 96.98 0.0 X-RAY
 2017-12-06 PHE A:327 A:327 0.0 0.0 H -58.5 -47.5 0.0 0.0 0.0 HOH
 4.756
 O
 O
5va9 1 P04746 96.98 0.0 X-RAY
 2018-03-28 PHE A:327 A:327 0.0 0.0 H -63.2 -46.8 0.0 0.0 0.0 HOH
 4.697
 O
 O
PHE B:327 B:327 0.0 0.0 H -63.7 -46.6 NA NA NA
6obx 1 P04746 96.98 0.0 X-RAY
 2020-02-12 PHE A:327 A:327 0.0 0.0 H -58.3 -48.2 0.0 0.0 0.0 HOH
 4.789
 O
 O
6ocn 1 P04746 96.98 0.0 X-RAY
 2020-02-12 PHE A:327 A:327 0.0 0.0 H -58.7 -47.6 0.0 0.0 0.0 HOH
 4.781
 O
 O
1kgw 1 P04746 96.77 0.0 X-RAY
 2002-01-16 PHE A:327 A:327 0.0 0.0 H -66.0 -42.5 0.0 0.0 0.0 HOH
 8.742
 O
 O
1xgz 1 P04746 96.77 0.0 X-RAY
 2005-05-24 PHE A:327 A:327 0.0 0.0 H -62.0 -47.8 0.0 0.0 0.0 HOH
 4.921
 O
 O
1xh0 1 P04746 96.77 0.0 X-RAY
 2005-05-24 PHE A:327 A:327 0.0 0.0 H -61.8 -45.5 0.0 0.0 0.0 HOH
 4.807
 O
 O
1xh1 1 P04746 96.77 0.0 X-RAY
 2005-05-24 PHE A:327 A:327 0.0 0.0 H -64.8 -43.9 0.0 0.0 0.0 HOH
 4.903
 O
 O
1xh2 1 P04746 96.77 0.0 X-RAY
 2005-05-24 PHE A:327 A:327 0.0 0.0 H -64.4 -43.9 0.0 0.0 0.0 HOH
 4.929
 O
 O
3bak 1 P04746 96.77 0.0 X-RAY
 2008-03-25 PHE A:327 A:327 0.0 0.0 H -62.1 -46.7 0.0 0.0 0.0 HOH
 4.696
 O
 O
3bax 1 P04746 96.77 0.0 X-RAY
 2008-03-25 PHE A:327 A:327 0.0 0.0 H -61.4 -45.4 0.0 0.0 0.0 HOH
 4.802
 O
 O
3bay 1 P04746 96.77 0.0 X-RAY
 2008-03-25 PHE A:327 A:327 0.0 0.0 H -60.2 -41.6 0.0 0.0 0.0 HOH
 4.853
 O
 O
1kgx 1 P04746 96.77 0.0 X-RAY
 2002-01-16 PHE A:327 A:327 0.0 0.0 H -64.5 -41.2 0.0 0.0 0.0 HOH
 2.783
 CB
 O
2cpu 1 P04746 96.77 0.0 X-RAY
 2001-06-30 PHE A:327 A:327 0.0 0.0 H -61.8 -42.5 0.0 0.0 0.0 HOH
 4.736
 O
 O
3cpu 1 P04746 96.77 0.0 X-RAY
 2001-06-30 PHE A:327 A:327 0.0 0.0 H -64.4 -44.9 0.0 0.0 0.0 HOH
 3.890
 CG
 O
5td4 1 P04746 96.77 0.0 X-RAY
 2016-11-02 PHE A:327 A:327 0.0 0.0 H -59.0 -49.9 0.0 0.0 0.0 HOH
 4.815
 O
 O
1kgu 1 P04746 96.77 0.0 X-RAY
 2002-01-16 PHE A:327 A:327 0.0 0.0 H -63.3 -42.5 0.0 0.0 0.0 HOH
 5.326
 N
 O
1kb3 1 P04746 96.77 0.0 X-RAY
 2002-05-01 PHE A:327 A:327 0.0 0.0 H -65.5 -40.3 0.0 0.0 0.0 HOH
 4.852
 O
 O
1kbb 1 P04746 96.77 0.0 X-RAY
 2002-04-10 PHE A:327 A:327 0.0 0.0 H -63.9 -43.9 0.0 0.0 0.0 HOH
 4.808
 O
 O
1kbk 1 P04746 96.77 0.0 X-RAY
 2002-04-10 PHE A:327 A:327 0.0 0.0 H -64.0 -44.4 0.0 0.0 0.0 HOH
 4.879
 O
 O
1kxq 1 P00690 86.29 0.0 X-RAY
 2002-06-19 PHE A:327 A:327 2.0 0.01 H -63.1 -45.1 2.0 0.01 0.0 HOH
 4.789
 O
 O
PHE B:327 B:327 3.0 0.014 H -61.7 -47.1 NA NA NA
PHE C:327 C:327 2.0 0.01 H -61.0 -47.9 NA NA NA
PHE D:327 D:327 0.0 0.0 H -63.6 -46.3 NA NA NA
1kxt 1 P00690 86.29 0.0 X-RAY
 2002-06-19 PHE A:327 A:327 1.0 0.005 H -70.8 -47.1 1.0 0.005 0.0 HOH
 3.534
 CD1
 O
PHE C:327 C:327 3.0 0.014 H -61.4 -39.5 NA NA NA
PHE E:327 E:327 4.0 0.019 H -62.2 -52.4 NA NA NA
1kxv 1 P00690 86.29 0.0 X-RAY
 2002-06-19 PHE A:327 A:327 4.0 0.019 H -62.0 -43.6 4.0 0.019 0.0 HOH
 4.800
 O
 O
PHE B:327 B:327 3.0 0.014 H -63.1 -44.6 NA NA NA
1dhk 1 P00690 86.29 0.0 X-RAY
 1997-12-24 PHE A:327 A:327 0.0 0.0 H -62.3 -46.7 0.0 0.0 0.0 HOH
 4.819
 O
 H1
1ppi 1 P00690 86.29 0.0 X-RAY
 1995-05-24 PHE A:327 A:327 3.0 0.014 H -66.5 -44.0 3.0 0.014 0.0 HOH
 4.917
 O
 O
1vah 1 P00690 86.09 0.0 X-RAY
 2005-04-26 PHE A:327 A:327 0.0 0.0 H -66.5 -38.4 0.0 0.0 0.0 HOH
 4.866
 O
 O
3l2l 1 P00690 86.09 0.0 X-RAY
 2010-04-14 PHE A:327 A:327 0.0 0.0 H -59.6 -45.0 0.0 0.0 0.0 HOH
 4.799
 O
 O
3l2m 1 P00690 86.09 0.0 X-RAY
 2010-04-14 PHE A:327 A:327 0.0 0.0 H -56.0 -47.8 0.0 0.0 0.0 HOH
 4.923
 O
 O
1ua3 1 P00690 86.09 0.0 X-RAY
 2003-10-14 PHE A:327 A:327 0.0 0.0 H -57.6 -47.3 0.0 0.0 0.0 HOH
 4.836
 O
 O
1ose 1 P00690 85.89 0.0 X-RAY
 1997-04-01 PHE A:327 A:327 0.0 0.0 H -63.6 -46.0 0.0 0.0 0.0 HOH
 4.905
 O
 O
1jfh 1 P00690 86.09 0.0 X-RAY
 1998-12-02 PHE A:327 A:327 0.0 0.0 H -65.3 -44.8 0.0 0.0 0.0 HOH
 4.888
 O
 O
1hx0 1 P00690 85.89 0.0 X-RAY
 2001-08-08 PHE A:327 A:327 0.0 0.0 H -59.2 -49.5 0.0 0.0 0.0 HOH
 4.809
 O
 O
1wo2 1 P00690 85.89 0.0 X-RAY
 2005-03-15 PHE A:327 A:327 0.0 0.0 H -63.4 -46.5 0.0 0.0 0.0 HOH
 4.864
 O
 O
1pif 1 P00690 85.69 0.0 X-RAY
 1996-12-07 PHE A:327 A:327 0.0 0.0 H -61.6 -51.2 0.0 0.0 0.0 HOH
 4.966
 O
 O
1pig 1 P00690 85.69 0.0 X-RAY
 1996-12-07 PHE A:327 A:327 0.0 0.0 H -62.2 -43.0 0.0 0.0 0.0 HOH
 4.743
 O
 O
4x0n 1 P00690 85.69 0.0 X-RAY
 2015-11-25 PHE A:327 A:327 0.0 0.0 H -59.4 -49.0 0.0 0.0 0.0 HOH
 6.817
 CZ
 O
1bvn 1 P00690 85.48 0.0 X-RAY
 1998-09-23 PHE A:327 P:327 0.0 0.0 H -49.6 -37.2 0.0 0.0 0.0 HOH
 4.909
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p0dte7-f1 1 P0DTE7 100.0 0.0 PHE A:342 A:342 0.0 0.0 H -60.3 -46.0
af-p0dte8-f1 1 P0DTE8 100.0 0.0 PHE A:342 A:342 0.0 0.0 H -60.1 -45.9
af-p0dub6-f1 1 P0DUB6 100.0 0.0 PHE A:342 A:342 0.0 0.0 H -60.3 -46.1
af-p19961-f1 1 P19961 97.46 0.0 PHE A:342 A:342 0.0 0.0 H -60.1 -45.2
af-p04746-f1 1 P04746 96.87 0.0 PHE A:342 A:342 0.0 0.0 H -60.7 -46.2