Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 104205525 . G A CCDS30782.1:NM_001008221.1:c.1238cGc>cAc_NP_001008222.1:p.413R>H Homo sapiens amylase, alpha 1A (salivary) (AMY1A), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1c8q 1 P04745 99.8 0.0 X-RAY
 2001-06-13 ARG A:398 A:398 14.0 0.062 H -63.8 -37.9 14.0 0.062 0.0 HOH
 2.961
 NE
 O
1mfv 1 P04745 99.8 0.0 X-RAY
 2002-11-20 ARG A:398 A:398 17.0 0.076 H -53.9 -42.4 17.0 0.076 0.0 HOH
 2.937
 NE
 O
1smd 1 P04745 99.8 0.0 X-RAY
 1996-07-11 ARG A:398 A:398 5.0 0.022 H -58.2 -42.1 5.0 0.022 0.0 HOH
 2.934
 NE
 O
1xv8 1 P04745 99.8 0.0 X-RAY
 2005-10-11 ARG A:398 A:398 13.0 0.058 H -56.7 -49.3 13.0 0.058 0.0 HOH
 2.746
 NE
 O
ARG B:398 B:398 14.0 0.062 H -56.7 -49.3 14.0 0.062 0.0 HOH
 2.747
 NE
 O
1q4n 1 P04745 99.6 0.0 X-RAY
 2004-03-16 ARG A:398 X:398 19.0 0.084 H -57.9 -41.8 19.0 0.084 0.0 HOH
 2.793
 NE
 O
1z32 1 P04745 99.6 0.0 X-RAY
 2005-05-31 ARG A:398 X:398 17.0 0.076 H -62.3 -39.4 17.0 0.076 0.0 HOH
 2.849
 NE
 O
1jxj 1 P04745 99.6 0.0 X-RAY
 2001-09-14 ARG A:398 A:398 16.0 0.071 H -60.8 -39.1 16.0 0.071 0.0 HOH
 2.862
 NE
 O
1nm9 1 P04745 99.6 0.0 X-RAY
 2004-01-20 ARG A:398 A:398 16.0 0.071 H -58.9 -43.7 16.0 0.071 0.0 HOH
 2.772
 NE
 O
3blk 1 P04745 99.6 0.0 X-RAY
 2008-11-25 ARG A:398 A:398 17.0 0.076 H -57.2 -40.6 17.0 0.076 0.0 HOH
 2.891
 NE
 O
3blp 1 P04745 99.6 0.0 X-RAY
 2008-11-18 ARG A:398 X:398 16.0 0.071 H -60.1 -38.3 16.0 0.071 0.0 HOH
 2.884
 NE
 O
1jxk 1 P04745 98.79 0.0 X-RAY
 2001-09-14 ARG A:393 A:393 16.0 0.071 H -59.3 -40.5 16.0 0.071 0.0 HOH
 2.852
 NE
 O
1mfu 1 P04745 98.79 0.0 X-RAY
 2002-11-20 ARG A:393 A:393 16.0 0.071 H -56.0 -43.7 16.0 0.071 0.0 HOH
 2.893
 NE
 O
3dhp 1 P04745 98.59 0.0 X-RAY
 2008-07-01 ARG A:398 A:398 16.0 0.071 H -59.9 -39.6 16.0 0.071 0.0 HOH
 2.886
 NE
 O
3old 1 P04746 97.38 0.0 X-RAY
 2011-04-13 ARG A:398 A:398 15.0 0.067 H -58.2 -40.3 15.0 0.067 0.0 HOH
 2.833
 NE
 O
3ole 1 P04746 97.38 0.0 X-RAY
 2011-04-13 ARG A:398 A:398 16.0 0.071 H -60.6 -37.3 16.0 0.071 0.0 HOH
 2.814
 NE
 O
3olg 1 P04746 97.38 0.0 X-RAY
 2011-04-13 ARG A:398 A:398 16.0 0.071 H -60.5 -38.0 16.0 0.071 0.0 HOH
 2.843
 NE
 O
3oli 1 P04746 97.38 0.0 X-RAY
 2011-04-13 ARG A:398 A:398 15.0 0.067 H -60.1 -38.2 15.0 0.067 0.0 HOH
 2.797
 NE
 O
6z8l 1 P04746 97.18 0.0 X-RAY
 2020-12-02 ARG A:398 A:398 16.0 0.071 H -60.9 -40.3 16.0 0.071 0.0 HOH
 2.047
 HE
 O
1b2y 1 P04746 97.18 0.0 X-RAY
 2000-02-16 ARG A:398 A:398 14.0 0.062 H -57.8 -42.4 14.0 0.062 0.0 HOH
 2.877
 NE
 O
1bsi 1 P04746 96.98 0.0 X-RAY
 1999-05-18 ARG A:398 A:398 17.0 0.076 H -63.1 -40.4 17.0 0.076 0.0 HOH
 3.076
 NE
 O
1cpu 1 P04746 96.98 0.0 X-RAY
 1999-06-14 ARG A:398 A:398 15.0 0.067 H -64.2 -39.1 15.0 0.067 0.0 HOH
 2.949
 NE
 O
1hny 1 P04746 96.98 0.0 X-RAY
 1996-03-08 ARG A:398 A:398 14.0 0.062 H -56.5 -44.1 14.0 0.062 0.0 HOH
 2.825
 NE
 O
1u2y 1 P04746 96.98 0.0 X-RAY
 2004-09-07 ARG A:398 A:398 16.0 0.071 H -60.8 -41.9 16.0 0.071 0.0 HOH
 2.950
 NE
 O
1u30 1 P04746 96.98 0.0 X-RAY
 2004-09-07 ARG A:398 A:398 16.0 0.071 H -61.5 -37.1 16.0 0.071 0.0 HOH
 2.963
 NE
 O
1u33 1 P04746 96.98 0.0 X-RAY
 2004-09-07 ARG A:398 A:398 15.0 0.067 H -62.2 -39.0 15.0 0.067 0.0 HOH
 2.896
 O
 O
1xcw 1 P04746 96.98 0.0 X-RAY
 2004-12-07 ARG A:398 A:398 15.0 0.067 H -62.5 -36.6 15.0 0.067 0.0 HOH
 2.873
 NE
 O
1xcx 1 P04746 96.98 0.0 X-RAY
 2004-12-07 ARG A:398 A:398 14.0 0.062 H -62.5 -37.8 14.0 0.062 0.0 HOH
 2.914
 O
 O
1xd0 1 P04746 96.98 0.0 X-RAY
 2004-12-07 ARG A:398 A:398 14.0 0.062 H -60.4 -40.5 14.0 0.062 0.0 HOH
 2.984
 NE
 O
1xd1 1 P04746 96.98 0.0 X-RAY
 2004-12-07 ARG A:398 A:398 15.0 0.067 H -65.7 -39.1 15.0 0.067 0.0 HOH
 2.953
 NE
 O
2qmk 1 P04746 96.98 0.0 X-RAY
 2008-03-25 ARG A:398 A:398 13.0 0.058 H -59.7 -39.3 13.0 0.058 0.0 HOH
 2.843
 NE
 O
2qv4 1 P04746 96.98 0.0 X-RAY
 2008-03-25 ARG A:398 A:398 15.0 0.067 H -61.9 -40.6 15.0 0.067 0.0 HOH
 2.819
 NE
 O
3bai 1 P04746 96.98 0.0 X-RAY
 2008-03-25 ARG A:398 A:398 16.0 0.071 H -62.5 -41.7 16.0 0.071 0.0 HOH
 2.999
 NE
 O
3baj 1 P04746 96.98 0.0 X-RAY
 2008-03-25 ARG A:398 A:398 15.0 0.067 H -62.7 -41.5 15.0 0.067 0.0 HOH
 2.891
 NE
 O
3baw 1 P04746 96.98 0.0 X-RAY
 2008-03-25 ARG A:398 A:398 15.0 0.067 H -59.2 -38.4 15.0 0.067 0.0 HOH
 2.931
 NE
 O
3ij7 1 P04746 96.98 0.0 X-RAY
 2009-10-27 ARG A:398 A:398 15.0 0.067 H -63.1 -37.6 15.0 0.067 0.0 HOH
 2.781
 NE
 O
3ij8 1 P04746 96.98 0.0 X-RAY
 2009-10-27 ARG A:398 A:398 14.0 0.062 H -59.7 -38.9 14.0 0.062 0.0 HOH
 2.809
 NE
 O
3ij9 1 P04746 96.98 0.0 X-RAY
 2009-10-27 ARG A:398 A:398 14.0 0.062 H -60.5 -38.3 14.0 0.062 0.0 HOH
 2.842
 NE
 O
4gqq 1 P04746 96.98 0.0 X-RAY
 2012-10-24 ARG A:398 A:398 16.0 0.071 H -60.4 -35.5 16.0 0.071 0.0 HOH
 2.757
 NE
 O
4gqr 1 P04746 96.98 0.0 X-RAY
 2012-10-24 ARG A:398 A:398 16.0 0.071 H -59.9 -39.0 16.0 0.071 0.0 HOH
 2.889
 NE
 O
4w93 1 P04746 96.98 0.0 X-RAY
 2015-07-15 ARG A:398 A:398 14.0 0.062 H -64.3 -36.7 14.0 0.062 0.0 HOH
 2.845
 NE
 O
4x9y 1 P04746 96.98 0.0 X-RAY
 2014-12-31 ARG A:398 A:398 15.0 0.067 H -62.0 -39.0 15.0 0.067 0.0 HOH
 1.961
 HE
 O
5e0f 1 P04746 96.98 0.0 X-RAY
 2016-09-07 ARG A:398 A:398 15.0 0.067 H -61.0 -41.0 15.0 0.067 0.0 HOH
 1.994
 HE
 O
5emy 1 P04746 96.98 0.0 X-RAY
 2016-07-06 ARG A:398 A:398 16.0 0.071 H -61.8 -39.8 16.0 0.071 0.0 HOH
 2.013
 HE
 O
5kez 1 P04746 96.98 0.0 X-RAY
 2017-03-29 ARG A:398 A:398 16.0 0.071 H -61.7 -36.4 16.0 0.071 0.0 HOH
 2.930
 NE
 O
5u3a 1 P04746 96.98 0.0 X-RAY
 2017-12-06 ARG A:398 A:398 14.0 0.062 H -61.3 -39.9 14.0 0.062 0.0 HOH
 1.965
 HE
 O
5va9 1 P04746 96.98 0.0 X-RAY
 2018-03-28 ARG A:398 A:398 15.0 0.067 H -65.3 -36.4 15.0 0.067 0.0 HOH
 3.152
 NE
 O
ARG B:398 B:398 15.0 0.067 H -64.6 -36.8 NA NA NA
6obx 1 P04746 96.98 0.0 X-RAY
 2020-02-12 ARG A:398 A:398 15.0 0.067 H -63.2 -38.2 15.0 0.067 0.0 HOH
 2.007
 HE
 O
6ocn 1 P04746 96.98 0.0 X-RAY
 2020-02-12 ARG A:398 A:398 14.0 0.062 H -61.8 -39.4 14.0 0.062 0.0 HOH
 1.988
 HE
 O
1kgw 1 P04746 96.77 0.0 X-RAY
 2002-01-16 ARG A:398 A:398 14.0 0.062 H -59.8 -38.2 14.0 0.062 0.0 HOH
 3.024
 NE
 O
1xgz 1 P04746 96.77 0.0 X-RAY
 2005-05-24 ARG A:398 A:398 15.0 0.067 H -60.5 -41.3 15.0 0.067 0.0 HOH
 2.925
 NE
 O
1xh0 1 P04746 96.77 0.0 X-RAY
 2005-05-24 ARG A:398 A:398 15.0 0.067 H -61.8 -41.9 15.0 0.067 0.0 HOH
 2.755
 NE
 O
1xh1 1 P04746 96.77 0.0 X-RAY
 2005-05-24 ARG A:398 A:398 17.0 0.076 H -61.3 -39.5 17.0 0.076 0.0 HOH
 2.955
 NE
 O
1xh2 1 P04746 96.77 0.0 X-RAY
 2005-05-24 ARG A:398 A:398 16.0 0.071 H -65.1 -39.0 16.0 0.071 0.0 HOH
 2.867
 NE
 O
3bak 1 P04746 96.77 0.0 X-RAY
 2008-03-25 ARG A:398 A:398 15.0 0.067 H -63.8 -37.1 15.0 0.067 0.0 HOH
 2.982
 NE
 O
3bax 1 P04746 96.77 0.0 X-RAY
 2008-03-25 ARG A:398 A:398 15.0 0.067 H -58.9 -39.5 15.0 0.067 0.0 HOH
 2.888
 NE
 O
3bay 1 P04746 96.77 0.0 X-RAY
 2008-03-25 ARG A:398 A:398 16.0 0.071 H -63.7 -41.1 16.0 0.071 0.0 HOH
 3.025
 NE
 O
1kgx 1 P04746 96.77 0.0 X-RAY
 2002-01-16 ARG A:398 A:398 18.0 0.08 H -66.6 -37.0 18.0 0.08 0.0 HOH
 2.839
 NE
 O
2cpu 1 P04746 96.77 0.0 X-RAY
 2001-06-30 ARG A:398 A:398 15.0 0.067 H -63.8 -36.7 15.0 0.067 0.0 HOH
 3.051
 NE
 O
3cpu 1 P04746 96.77 0.0 X-RAY
 2001-06-30 ARG A:398 A:398 15.0 0.067 H -61.8 -37.1 15.0 0.067 0.0 HOH
 3.015
 NE
 O
5td4 1 P04746 96.77 0.0 X-RAY
 2016-11-02 ARG A:398 A:398 14.0 0.062 H -58.5 -41.8 14.0 0.062 0.0 HOH
 3.048
 NE
 O
1kgu 1 P04746 96.77 0.0 X-RAY
 2002-01-16 ARG A:398 A:398 18.0 0.08 H -60.7 -38.8 18.0 0.08 0.0 HOH
 2.885
 NE
 O
1kb3 1 P04746 96.77 0.0 X-RAY
 2002-05-01 ARG A:398 A:398 17.0 0.076 H -66.5 -38.5 17.0 0.076 0.0 HOH
 2.879
 NE
 O
1kbb 1 P04746 96.77 0.0 X-RAY
 2002-04-10 ARG A:398 A:398 14.0 0.062 H -60.6 -37.3 14.0 0.062 0.0 HOH
 2.811
 NE
 O
1kbk 1 P04746 96.77 0.0 X-RAY
 2002-04-10 ARG A:398 A:398 16.0 0.071 H -62.5 -38.3 16.0 0.071 0.0 HOH
 3.014
 NE
 O
1kxq 1 P00690 86.29 0.0 X-RAY
 2002-06-19 ARG A:398 A:398 12.0 0.053 H -58.8 -36.2 12.0 0.053 0.0 HOH
 2.862
 NE
 O
ARG B:398 B:398 12.0 0.053 H -59.4 -38.7 NA NA NA
ARG C:398 C:398 14.0 0.062 H -60.5 -34.7 NA NA NA
ARG D:398 D:398 15.0 0.067 H -59.2 -37.7 NA NA NA
1kxt 1 P00690 86.29 0.0 X-RAY
 2002-06-19 ARG A:398 A:398 15.0 0.067 H -60.2 -41.1 15.0 0.067 0.0 HOH
 2.628
 NE
 O
ARG C:398 C:398 11.0 0.049 H -59.2 -40.2 NA NA NA
ARG E:398 E:398 9.0 0.04 H -58.8 -40.2 NA NA NA
1kxv 1 P00690 86.29 0.0 X-RAY
 2002-06-19 ARG A:398 A:398 13.0 0.058 H -63.4 -34.8 13.0 0.058 0.0 HOH
 2.790
 O
 O
ARG B:398 B:398 16.0 0.071 H -60.5 -38.6 NA NA NA
1dhk 1 P00690 86.29 0.0 X-RAY
 1997-12-24 ARG A:398 A:398 16.0 0.071 H -59.2 -36.9 16.0 0.071 0.0 HOH
 1.906
 HE
 H1
1ppi 1 P00690 86.29 0.0 X-RAY
 1995-05-24 ARG A:398 A:398 14.0 0.062 H -61.5 -30.5 14.0 0.062 0.0 HOH
 2.770
 NE
 O
1vah 1 P00690 86.09 0.0 X-RAY
 2005-04-26 ARG A:398 A:398 15.0 0.067 H -60.5 -41.5 15.0 0.067 0.0 HOH
 3.811
 CB
 O
3l2l 1 P00690 86.09 0.0 X-RAY
 2010-04-14 ARG A:398 A:398 15.0 0.067 H -61.9 -40.9 15.0 0.067 0.0 HOH
 1.966
 HE
 O
3l2m 1 P00690 86.09 0.0 X-RAY
 2010-04-14 ARG A:398 A:398 14.0 0.062 H -60.4 -38.8 14.0 0.062 0.0 HOH
 1.914
 HE
 O
1ua3 1 P00690 86.09 0.0 X-RAY
 2003-10-14 ARG A:398 A:398 15.0 0.067 H -66.0 -38.2 15.0 0.067 0.0 HOH
 2.829
 NE
 O
1ose 1 P00690 85.89 0.0 X-RAY
 1997-04-01 ARG A:398 A:398 12.0 0.053 H -57.7 -40.5 12.0 0.053 0.0 HOH
 2.806
 O
 O
1jfh 1 P00690 86.09 0.0 X-RAY
 1998-12-02 ARG A:398 A:398 17.0 0.076 H -60.6 -35.8 17.0 0.076 0.0 HOH
 2.839
 NE
 O
1hx0 1 P00690 85.89 0.0 X-RAY
 2001-08-08 ARG A:398 A:398 14.0 0.062 H -60.9 -37.4 14.0 0.062 0.0 HOH
 2.858
 NE
 O
1wo2 1 P00690 85.89 0.0 X-RAY
 2005-03-15 ARG A:398 A:398 14.0 0.062 H -59.1 -39.1 14.0 0.062 0.0 HOH
 2.797
 NE
 O
1pif 1 P00690 85.69 0.0 X-RAY
 1996-12-07 ARG A:398 A:398 17.0 0.076 H -57.7 -40.2 17.0 0.076 0.0 HOH
 2.949
 NE
 O
1pig 1 P00690 85.69 0.0 X-RAY
 1996-12-07 ARG A:398 A:398 15.0 0.067 H -62.0 -39.9 15.0 0.067 0.0 HOH
 2.954
 NE
 O
4x0n 1 P00690 85.69 0.0 X-RAY
 2015-11-25 ARG A:398 A:398 14.0 0.062 H -62.3 -36.4 14.0 0.062 0.0 HOH
 2.880
 NE
 O
1bvn 1 P00690 85.48 0.0 X-RAY
 1998-09-23 ARG A:398 P:398 14.0 0.062 H -63.7 -22.3 14.0 0.062 0.0 HOH
 3.008
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p0dte7-f1 1 P0DTE7 100.0 0.0 ARG A:413 A:413 17.0 0.076 H -58.3 -42.7
af-p0dte8-f1 1 P0DTE8 100.0 0.0 ARG A:413 A:413 17.0 0.076 H -57.9 -42.9
af-p0dub6-f1 1 P0DUB6 100.0 0.0 ARG A:413 A:413 16.0 0.071 H -58.1 -42.2
af-p19961-f1 1 P19961 97.46 0.0 ARG A:413 A:413 17.0 0.076 H -58.3 -42.3
af-p04746-f1 1 P04746 96.87 0.0 ARG A:413 A:413 17.0 0.076 H -57.4 -43.0