Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 104233963 . G A CCDS30783.1:NM_001008218.1:c.1054Cga>Tga_NP_001008219.1:p.352R>* Homo sapiens amylase, alpha 1B (salivary) (AMY1B), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1c8q 1 P04745 99.8 0.0 X-RAY
 2001-06-13 ARG A:337 A:337 3.0 0.013 E -118.7 127.8 3.0 0.013 0.0 CL
HOH
 3.049
2.898
 NH2
O
 CL
O
1mfv 1 P04745 99.8 0.0 X-RAY
 2002-11-20 ARG A:337 A:337 4.0 0.018 E -121.3 125.8 4.0 0.018 0.0 AGL
HMC
CL
HOH
 9.867
8.111
3.098
2.784
 NH2
NH2
NH2
O
 N4
O2
CL
O
1smd 1 P04745 99.8 0.0 X-RAY
 1996-07-11 ARG A:337 A:337 3.0 0.013 E -119.9 124.7 3.0 0.013 0.0 CL
HOH
 3.260
2.800
 NH2
O
 CL
O
1xv8 1 P04745 99.8 0.0 X-RAY
 2005-10-11 ARG A:337 A:337 5.0 0.022 E -137.9 127.7 5.0 0.022 0.0 CL
HOH
 3.172
2.702
 NH2
O
 CL
O
ARG B:337 B:337 6.0 0.027 E -137.9 127.8 6.0 0.027 0.0 CL
HOH
 3.173
2.702
 NH2
O
 CL
O
1q4n 1 P04745 99.6 0.0 X-RAY
 2004-03-16 ARG A:337 X:337 4.0 0.018 E -116.6 131.7 4.0 0.018 0.0 CL
HOH
 3.211
2.733
 NH2
NE
 CL
O
1z32 1 P04745 99.6 0.0 X-RAY
 2005-05-31 ARG A:337 X:337 4.0 0.018 E -118.7 126.0 4.0 0.018 0.0 HMC
CL
HOH
 8.161
3.227
2.694
 NH1
NH2
O
 O2
CL
O
1jxj 1 P04745 99.6 0.0 X-RAY
 2001-09-14 ARG A:337 A:337 4.0 0.018 E -121.9 128.0 4.0 0.018 0.0 CL
HOH
 3.198
2.769
 NH2
NE
 CL
O
1nm9 1 P04745 99.6 0.0 X-RAY
 2004-01-20 ARG A:337 A:337 4.0 0.018 E -120.5 126.8 4.0 0.018 0.0 AGL
HMC
CL
HOH
 9.928
8.130
3.153
2.705
 NH2
NH2
NH2
NE
 N4
O2
CL
O
3blk 1 P04745 99.6 0.0 X-RAY
 2008-11-25 ARG A:337 A:337 3.0 0.013 E -124.4 127.4 3.0 0.013 0.0 CL
HMC
HOH
 3.030
8.285
2.674
 NH2
NH2
O
 CL
O2
O
3blp 1 P04745 99.6 0.0 X-RAY
 2008-11-18 ARG A:337 X:337 3.0 0.013 E -120.0 129.0 3.0 0.013 0.0 CL
HMC
HOH
 3.235
8.313
2.689
 NH2
NH2
O
 CL
O2
O
1jxk 1 P04745 98.79 0.0 X-RAY
 2001-09-14 ARG A:332 A:332 3.0 0.013 E -120.3 127.7 3.0 0.013 0.0 CL
HOH
 3.210
2.745
 NH2
NE
 CL
O
1mfu 1 P04745 98.79 0.0 X-RAY
 2002-11-20 ARG A:332 A:332 4.0 0.018 E -121.2 126.8 4.0 0.018 0.0 AGL
HMC
CL
HOH
 9.728
8.030
3.098
2.689
 NH2
NH2
NH2
O
 N4
O2
CL
O
3dhp 1 P04745 98.59 0.0 X-RAY
 2008-07-01 ARG A:337 A:337 4.0 0.018 E -121.6 127.8 4.0 0.018 0.0 CL
HMC
HOH
 3.183
8.152
2.761
 NH2
NH2
NE
 CL
O2
O
3old 1 P04746 97.38 0.0 X-RAY
 2011-04-13 ARG A:337 A:337 4.0 0.018 E -120.3 123.9 4.0 0.018 0.0 CL
ACI
HOH
 3.035
8.006
2.751
 NH2
NH2
O
 CL
O2
O
3ole 1 P04746 97.38 0.0 X-RAY
 2011-04-13 ARG A:337 A:337 3.0 0.013 E -119.5 125.4 3.0 0.013 0.0 CL
ACI
HOH
 3.171
8.105
2.678
 NH2
NH2
O
 CL
O2
O
3olg 1 P04746 97.38 0.0 X-RAY
 2011-04-13 ARG A:337 A:337 2.0 0.009 E -119.5 131.6 2.0 0.009 0.0 CL
HSD
HOH
 3.318
8.195
2.608
 NH2
NH1
NE
 CL
O4
O
3oli 1 P04746 97.38 0.0 X-RAY
 2011-04-13 ARG A:337 A:337 3.0 0.013 E -121.6 126.2 3.0 0.013 0.0 CL
HSD
HOH
 3.216
8.211
2.768
 NH2
NH2
NE
 CL
O4
O
6z8l 1 P04746 97.18 0.0 X-RAY
 2020-12-02 ARG A:337 A:337 4.0 0.018 E -120.4 125.0 4.0 0.018 0.0 GLC
CL
HOH
 9.252
2.441
2.070
 HH22
HH22
HE
 O1
CL
O
1b2y 1 P04746 97.18 0.0 X-RAY
 2000-02-16 ARG A:337 A:337 6.0 0.027 E -114.5 127.3 6.0 0.027 0.0 AC1
CL
HOH
 8.248
3.367
2.526
 NH1
NH2
O
 O2B
CL
O
1bsi 1 P04746 96.98 0.0 X-RAY
 1999-05-18 ARG A:337 A:337 5.0 0.022 E -119.7 126.6 5.0 0.022 0.0 CL
HOH
 3.136
2.862
 NH2
NE
 CL
O
1cpu 1 P04746 96.98 0.0 X-RAY
 1999-06-14 ARG A:337 A:337 5.0 0.022 E -121.4 122.8 5.0 0.022 0.0 CL
HMC
HOH
 3.264
8.312
2.738
 NH2
NH2
O
 CL
O2
O
1hny 1 P04746 96.98 0.0 X-RAY
 1996-03-08 ARG A:337 A:337 4.0 0.018 E -118.7 126.8 4.0 0.018 0.0 CL
HOH
 3.155
2.712
 NH2
NE
 CL
O
1u2y 1 P04746 96.98 0.0 X-RAY
 2004-09-07 ARG A:337 A:337 4.0 0.018 E -120.5 127.0 4.0 0.018 0.0 CL
HOH
 3.108
2.841
 NH2
O
 CL
O
1u30 1 P04746 96.98 0.0 X-RAY
 2004-09-07 ARG A:337 A:337 5.0 0.022 E -124.7 122.4 5.0 0.022 0.0 LAG
CL
HOH
 8.775
3.107
2.701
 NH2
NH2
NE
 OA2
CL
O
1u33 1 P04746 96.98 0.0 X-RAY
 2004-09-07 ARG A:337 A:337 2.0 0.009 E -122.1 123.0 2.0 0.009 0.0 LM2
CL
HOH
 8.256
3.075
2.758
 NH2
NH2
O
 OA2
CL
O
1xcw 1 P04746 96.98 0.0 X-RAY
 2004-12-07 ARG A:337 A:337 5.0 0.022 E -121.4 121.5 5.0 0.022 0.0 AC1
CL
HOH
 7.960
3.131
2.717
 NH2
NH2
O
 O2B
CL
O
1xcx 1 P04746 96.98 0.0 X-RAY
 2004-12-07 ARG A:337 A:337 6.0 0.027 E -122.6 125.8 6.0 0.027 0.0 AC1
CL
HOH
 8.060
3.107
2.754
 NH2
NH2
O
 O2B
CL
O
1xd0 1 P04746 96.98 0.0 X-RAY
 2004-12-07 ARG A:337 A:337 4.0 0.018 E -118.9 126.2 4.0 0.018 0.0 ARE
CL
HOH
 8.167
3.135
2.773
 NH2
NH2
O
 O2H
CL
O
1xd1 1 P04746 96.98 0.0 X-RAY
 2004-12-07 ARG A:337 A:337 7.0 0.031 E -118.5 129.8 7.0 0.031 0.0 6SA
CL
HOH
 8.216
3.129
2.899
 NH2
NH2
NE
 OQ2
CL
O
2qmk 1 P04746 96.98 0.0 X-RAY
 2008-03-25 ARG A:337 A:337 4.0 0.018 E -124.4 118.5 4.0 0.018 0.0 NO2
HOH
 2.718
2.804
 NH2
O
 O2
O
2qv4 1 P04746 96.98 0.0 X-RAY
 2008-03-25 ARG A:337 A:337 4.0 0.018 E -118.6 121.5 4.0 0.018 0.0 NO2
QV4
HOH
 2.817
8.293
2.712
 NH2
NH2
O
 N
O2T
O
3bai 1 P04746 96.98 0.0 X-RAY
 2008-03-25 ARG A:337 A:337 4.0 0.018 E -121.7 127.8 4.0 0.018 0.0 NO3
HOH
 2.647
2.946
 NH2
O
 O3
O
3baj 1 P04746 96.98 0.0 X-RAY
 2008-03-25 ARG A:337 A:337 4.0 0.018 E -121.7 130.1 4.0 0.018 0.0 ARE
NO3
HOH
 8.253
2.598
2.871
 NH2
NH2
O
 O2H
O3
O
3baw 1 P04746 96.98 0.0 X-RAY
 2008-03-25 ARG A:337 A:337 2.0 0.009 E -126.6 120.8 2.0 0.009 0.0 CL
HOH
 3.222
2.817
 NH2
O
 CL
O
3ij7 1 P04746 96.98 0.0 X-RAY
 2009-10-27 ARG A:337 A:337 3.0 0.013 E -123.3 122.5 3.0 0.013 0.0 B9D
CL
HOH
 8.484
3.087
2.751
 NH1
NH2
O
 O4
CL
O
3ij8 1 P04746 96.98 0.0 X-RAY
 2009-10-27 ARG A:337 A:337 3.0 0.013 E -122.1 123.8 3.0 0.013 0.0 B9D
CL
HOH
 8.489
3.168
2.697
 NH1
NH2
O
 O4
CL
O
3ij9 1 P04746 96.98 0.0 X-RAY
 2009-10-27 ARG A:337 A:337 2.0 0.009 E -121.0 122.9 2.0 0.009 0.0 B9D
CL
HOH
 8.186
3.007
2.694
 NH1
NH2
O
 O4
CL
O
4gqq 1 P04746 96.98 0.0 X-RAY
 2012-10-24 ARG A:337 A:337 18.0 0.08 E -126.0 126.1 18.0 0.08 0.0 CL
HOH
 3.414
2.544
 NH1
NE
 CL
O
4gqr 1 P04746 96.98 0.0 X-RAY
 2012-10-24 ARG A:337 A:337 4.0 0.018 E -119.1 118.3 4.0 0.018 0.0 CL
HOH
 3.056
2.735
 NH2
O
 CL
O
4w93 1 P04746 96.98 0.0 X-RAY
 2015-07-15 ARG A:337 A:337 2.0 0.009 E -118.4 126.3 2.0 0.009 0.0 CL
3L9
HOH
 3.174
8.692
2.780
 NH2
NH1
O
 CL
O4F
O
4x9y 1 P04746 96.98 0.0 X-RAY
 2014-12-31 ARG A:337 A:337 3.0 0.013 E -118.8 126.1 3.0 0.013 0.0 CL
HOH
 2.400
2.134
 HH22
HE
 CL
O
5e0f 1 P04746 96.98 0.0 X-RAY
 2016-09-07 ARG A:337 A:337 4.0 0.018 E -117.6 126.6 4.0 0.018 0.0 5J7
CL
HOH
 7.410
2.350
2.150
 HH22
HH22
HE
 H63
CL
O
5emy 1 P04746 96.98 0.0 X-RAY
 2016-07-06 ARG A:337 A:337 3.0 0.013 E -116.5 126.5 3.0 0.013 0.0 5QP
CL
HOH
 7.716
2.381
2.117
 HH12
HH22
HE
 OAD
CL
O
5kez 1 P04746 96.98 0.0 X-RAY
 2017-03-29 ARG A:337 A:337 3.0 0.013 E -118.6 131.7 3.0 0.013 0.0 CL
HOH
 3.219
2.773
 NH2
O
 CL
O
5u3a 1 P04746 96.98 0.0 X-RAY
 2017-12-06 ARG A:337 A:337 2.0 0.009 E -118.5 124.9 2.0 0.009 0.0 CL
HOH
 2.383
2.105
 HH22
HE
 CL
O
5va9 1 P04746 96.98 0.0 X-RAY
 2018-03-28 ARG A:337 A:337 3.0 0.013 E -117.2 124.6 3.0 0.013 0.0 CL
HOH
 3.129
2.490
 NH2
O
 CL
O
ARG B:337 B:337 4.0 0.018 E -118.4 125.0 NA NA NA
6obx 1 P04746 96.98 0.0 X-RAY
 2020-02-12 ARG A:337 A:337 3.0 0.013 E -117.5 125.9 3.0 0.013 0.0 CL
ZXU
HOH
 2.400
7.890
2.112
 HH22
HH22
HE
 CL
HO61
O
6ocn 1 P04746 96.98 0.0 X-RAY
 2020-02-12 ARG A:337 A:337 2.0 0.009 E -118.6 125.4 2.0 0.009 0.0 ZXY
CL
HOH
 7.158
2.393
2.135
 HH12
HH22
HE
 HO37
CL
O
1kgw 1 P04746 96.77 0.0 X-RAY
 2002-01-16 GLN A:337 A:337 8.0 0.044 E -123.0 123.3 8.0 0.044 0.0 HOH
 2.827
 NE2
 O
1xgz 1 P04746 96.77 0.0 X-RAY
 2005-05-24 ARG A:337 A:337 5.0 0.022 E -115.6 122.9 5.0 0.022 0.0 HOH
 2.831
 O
 O
1xh0 1 P04746 96.77 0.0 X-RAY
 2005-05-24 ARG A:337 A:337 7.0 0.031 E -119.3 128.5 7.0 0.031 0.0 AAO
HOH
 7.907
2.788
 NH2
O
 O2H
O
1xh1 1 P04746 96.77 0.0 X-RAY
 2005-05-24 ARG A:337 A:337 7.0 0.031 E -118.7 123.0 7.0 0.031 0.0 CL
HOH
 3.127
2.827
 NH2
O
 CL
O
1xh2 1 P04746 96.77 0.0 X-RAY
 2005-05-24 ARG A:337 A:337 7.0 0.031 E -119.7 122.6 7.0 0.031 0.0 ARE
CL
HOH
 8.063
3.156
2.833
 NH2
NH2
NE
 O2H
CL
O
3bak 1 P04746 96.77 0.0 X-RAY
 2008-03-25 ARG A:337 A:337 6.0 0.027 E -117.7 123.8 6.0 0.027 0.0 NO3
HOH
 2.632
2.768
 NH1
O
 O2
O
3bax 1 P04746 96.77 0.0 X-RAY
 2008-03-25 ARG A:337 A:337 4.0 0.018 E -119.8 122.9 4.0 0.018 0.0 CL
HOH
 3.140
2.713
 NH2
O
 CL
O
3bay 1 P04746 96.77 0.0 X-RAY
 2008-03-25 ARG A:337 A:337 7.0 0.031 E -120.1 131.2 7.0 0.031 0.0 ARE
NO3
HOH
 8.249
2.749
2.790
 NH1
NH1
O
 O2H
O2
O
1kgx 1 P04746 96.77 0.0 X-RAY
 2002-01-16 ARG A:337 A:337 7.0 0.031 E -118.7 121.0 7.0 0.031 0.0 HOH
 2.697
 O
 O
2cpu 1 P04746 96.77 0.0 X-RAY
 2001-06-30 ARG A:337 A:337 4.0 0.018 E -119.3 125.7 4.0 0.018 0.0 CL
HOH
 3.172
2.860
 NH2
NE
 CL
O
3cpu 1 P04746 96.77 0.0 X-RAY
 2001-06-30 ARG A:337 A:337 6.0 0.027 E -113.8 128.0 6.0 0.027 0.0 CL
HOH
 3.208
2.683
 NH2
NE
 CL
O
5td4 1 P04746 96.77 0.0 X-RAY
 2016-11-02 ARG A:337 A:337 3.0 0.013 E -112.3 129.6 3.0 0.013 0.0 GLC
CL
HOH
 8.570
3.251
2.567
 NH1
NH2
NE
 O2
CL
O
1kgu 1 P04746 96.77 0.0 X-RAY
 2002-01-16 ALA A:337 A:337 13.0 0.113 E -121.8 123.7 13.0 0.113 0.0 HOH
 2.779
 O
 O
1kb3 1 P04746 96.77 0.0 X-RAY
 2002-05-01 ARG A:337 A:337 16.0 0.071 E -125.5 124.6 16.0 0.071 0.0 HOH
 2.708
 NE
 O
1kbb 1 P04746 96.77 0.0 X-RAY
 2002-04-10 ARG A:337 A:337 4.0 0.018 E -119.5 128.0 4.0 0.018 0.0 CL
HOH
 3.190
2.718
 NH2
NE
 CL
O
1kbk 1 P04746 96.77 0.0 X-RAY
 2002-04-10 ARG A:337 A:337 3.0 0.013 E -122.5 126.9 3.0 0.013 0.0 CL
HOH
 3.099
2.821
 NH2
O
 CL
O
1kxq 1 P00690 86.29 0.0 X-RAY
 2002-06-19 ARG A:337 A:337 4.0 0.018 E -121.4 128.8 4.0 0.018 0.0 CL
HOH
 3.189
2.780
 NH1
O
 CL
O
ARG B:337 B:337 3.0 0.013 E -122.1 128.0 NA NA NA
ARG C:337 C:337 3.0 0.013 E -120.8 127.7 NA NA NA
ARG D:337 D:337 3.0 0.013 E -120.2 128.5 NA NA NA
1kxt 1 P00690 86.29 0.0 X-RAY
 2002-06-19 ARG A:337 A:337 5.0 0.022 E -121.6 122.9 5.0 0.022 0.0 CL
HOH
 3.347
2.645
 NH2
O
 CL
O
ARG C:337 C:337 5.0 0.022 E -123.0 125.9 NA NA NA
ARG E:337 E:337 4.0 0.018 E -123.5 129.0 NA NA NA
1kxv 1 P00690 86.29 0.0 X-RAY
 2002-06-19 ARG A:337 A:337 6.0 0.027 E -121.2 126.7 6.0 0.027 0.0 HOH
 2.746
 NE
 O
ARG B:337 B:337 5.0 0.022 E -121.8 126.1 NA NA NA
1dhk 1 P00690 86.29 0.0 X-RAY
 1997-12-24 ARG A:337 A:337 5.0 0.022 E -123.8 128.0 5.0 0.022 0.0 CL
HOH
 1.900
2.087
 HH22
HE
 CL
H1
1ppi 1 P00690 86.29 0.0 X-RAY
 1995-05-24 ARG A:337 A:337 5.0 0.022 E -115.3 125.5 5.0 0.022 0.0 DAF
CL
HOH
 8.304
3.467
2.827
 NH1
NH2
NE
 O2H
CL
O
1vah 1 P00690 86.09 0.0 X-RAY
 2005-04-26 ARG A:337 A:337 6.0 0.027 E -123.6 125.7 6.0 0.027 0.0 CL
HOH
 3.161
2.651
 NH1
O
 CL
O
3l2l 1 P00690 86.09 0.0 X-RAY
 2010-04-14 ARG A:337 A:337 4.0 0.018 E -115.7 131.6 4.0 0.018 0.0 GLC
CL
HOH
 9.101
2.298
2.096
 HH22
HH22
HE
 H2
CL
O
3l2m 1 P00690 86.09 0.0 X-RAY
 2010-04-14 ARG A:337 A:337 5.0 0.022 E -120.2 131.0 5.0 0.022 0.0 CL
HOH
 2.344
2.152
 HH22
HE
 CL
O
1ua3 1 P00690 86.09 0.0 X-RAY
 2003-10-14 ARG A:337 A:337 4.0 0.018 E -116.3 128.4 4.0 0.018 0.0 GLC
CL
HOH
 8.316
3.182
2.717
 NH1
NH2
NE
 O2
CL
O
1ose 1 P00690 85.89 0.0 X-RAY
 1997-04-01 ARG A:337 A:337 4.0 0.018 E -119.0 129.3 4.0 0.018 0.0 AC1
CL
HOH
 8.408
3.083
2.939
 NH2
NH2
O
 O2B
CL
O
1jfh 1 P00690 86.09 0.0 X-RAY
 1998-12-02 ARG A:337 A:337 5.0 0.022 E -122.1 124.1 5.0 0.022 0.0 CL
HOH
 3.102
2.786
 NH2
O
 CL
O
1hx0 1 P00690 85.89 0.0 X-RAY
 2001-08-08 ARG A:337 A:337 4.0 0.018 E -120.2 127.0 4.0 0.018 0.0 AC1
CL
HOH
 8.273
3.179
2.768
 NH2
NH1
O
 O2B
CL
O
1wo2 1 P00690 85.89 0.0 X-RAY
 2005-03-15 ARG A:337 A:337 4.0 0.018 E -120.1 119.4 4.0 0.018 0.0 BGC
CL
HOH
 8.296
3.050
2.654
 NH1
NH1
O
 O2
CL
O
1pif 1 P00690 85.69 0.0 X-RAY
 1996-12-07 ARG A:337 A:337 4.0 0.018 E -122.0 126.2 4.0 0.018 0.0 CL
HOH
 3.137
2.643
 NH2
O
 CL
O
1pig 1 P00690 85.69 0.0 X-RAY
 1996-12-07 ARG A:337 A:337 6.0 0.027 E -122.3 122.0 6.0 0.027 0.0 AGL
HMC
CL
HOH
 9.870
8.075
3.109
2.655
 NH2
NH2
NH2
O
 N4
O2
CL
O
4x0n 1 P00690 85.69 0.0 X-RAY
 2015-11-25 ARG A:337 A:337 3.0 0.013 E -120.6 128.0 3.0 0.013 0.0 CL
HOH
 3.169
2.671
 NH2
NE
 CL
O
1bvn 1 P00690 85.48 0.0 X-RAY
 1998-09-23 ARG A:337 P:337 3.0 0.013 E -119.1 128.7 3.0 0.013 0.0 CL
HOH
 3.196
2.800
 NH2
NE
 CL
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p0dte7-f1 1 P0DTE7 100.0 0.0 ARG A:352 A:352 3.0 0.013 E -109.8 122.9
af-p0dte8-f1 1 P0DTE8 100.0 0.0 ARG A:352 A:352 3.0 0.013 E -110.1 123.2
af-p0dub6-f1 1 P0DUB6 100.0 0.0 ARG A:352 A:352 3.0 0.013 E -110.7 123.9
af-p19961-f1 1 P19961 97.46 0.0 ARG A:352 A:352 2.0 0.009 E -109.7 123.9
af-p04746-f1 1 P04746 96.87 0.0 ARG A:352 A:352 3.0 0.013 E -109.6 124.1