Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 104234189 . G A CCDS30783.1:NM_001008218.1:c.922Ctt>Ttt_NP_001008219.1:p.308L>F Homo sapiens amylase, alpha 1B (salivary) (AMY1B), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1c8q 1 P04745 99.8 0.0 X-RAY
 2001-06-13 LEU A:293 A:293 0.0 0.0 E -112.2 103.3 0.0 0.0 0.0 CL
HOH
 6.174
5.382
 CD1
O
 CL
O
1mfv 1 P04745 99.8 0.0 X-RAY
 2002-11-20 LEU A:293 A:293 0.0 0.0 E -103.6 113.4 0.0 0.0 0.0 CL
HOH
 6.137
5.578
 CD1
O
 CL
O
1smd 1 P04745 99.8 0.0 X-RAY
 1996-07-11 LEU A:293 A:293 0.0 0.0 E -113.6 115.2 0.0 0.0 0.0 CL
HOH
 6.117
5.588
 CD1
O
 CL
O
1xv8 1 P04745 99.8 0.0 X-RAY
 2005-10-11 LEU A:293 A:293 0.0 0.0 E -127.5 103.4 0.0 0.0 0.0 CL
HOH
 5.963
7.200
 CD1
CD2
 CL
O
LEU B:293 B:293 0.0 0.0 E -127.5 103.5 0.0 0.0 0.0 CL
HOH
 5.963
7.200
 CD1
CD2
 CL
O
1q4n 1 P04745 99.6 0.0 X-RAY
 2004-03-16 LEU A:293 X:293 0.0 0.0 E -112.4 112.2 0.0 0.0 0.0 CL
HOH
 6.199
5.536
 CD1
O
 CL
O
1z32 1 P04745 99.6 0.0 X-RAY
 2005-05-31 LEU A:293 X:293 0.0 0.0 E -102.8 115.0 0.0 0.0 0.0 CL
HOH
 6.119
5.568
 CD1
O
 CL
O
1jxj 1 P04745 99.6 0.0 X-RAY
 2001-09-14 LEU A:293 A:293 0.0 0.0 E -108.8 108.8 0.0 0.0 0.0 CL
HOH
 6.187
5.541
 CD1
O
 CL
O
1nm9 1 P04745 99.6 0.0 X-RAY
 2004-01-20 LEU A:293 A:293 0.0 0.0 E -105.2 112.4 0.0 0.0 0.0 CL
HOH
 6.153
5.561
 CD1
O
 CL
O
3blk 1 P04745 99.6 0.0 X-RAY
 2008-11-25 LEU A:293 A:293 0.0 0.0 E -101.6 114.1 0.0 0.0 0.0 CL
HOH
 6.169
5.740
 CD1
O
 CL
O
3blp 1 P04745 99.6 0.0 X-RAY
 2008-11-18 LEU A:293 X:293 0.0 0.0 E -105.0 113.3 0.0 0.0 0.0 CL
HOH
 6.074
5.684
 CD1
O
 CL
O
1jxk 1 P04745 98.79 0.0 X-RAY
 2001-09-14 LEU A:293 A:293 0.0 0.0 E -110.0 110.0 0.0 0.0 0.0 CL
HOH
 6.041
5.472
 CD1
O
 CL
O
1mfu 1 P04745 98.79 0.0 X-RAY
 2002-11-20 LEU A:293 A:293 0.0 0.0 E -105.9 115.0 0.0 0.0 0.0 CL
HOH
 6.026
5.641
 CD1
O
 CL
O
3dhp 1 P04745 98.59 0.0 X-RAY
 2008-07-01 LEU A:293 A:293 0.0 0.0 E -106.9 118.2 0.0 0.0 0.0 CL
HOH
 6.169
5.691
 CD1
O
 CL
O
3old 1 P04746 97.38 0.0 X-RAY
 2011-04-13 LEU A:293 A:293 0.0 0.0 E -112.8 111.5 0.0 0.0 0.0 CL
PCA
HOH
 5.985
9.205
5.715
 CD1
CD2
O
 CL
O
O
3ole 1 P04746 97.38 0.0 X-RAY
 2011-04-13 LEU A:293 A:293 0.0 0.0 E -114.1 111.4 0.0 0.0 0.0 CL
PCA
HOH
 6.021
9.252
5.667
 CD1
CD2
O
 CL
O
O
3olg 1 P04746 97.38 0.0 X-RAY
 2011-04-13 LEU A:293 A:293 0.0 0.0 E -113.2 107.9 0.0 0.0 0.0 CL
PCA
HOH
 6.030
9.156
5.739
 CD1
CD2
O
 CL
O
O
3oli 1 P04746 97.38 0.0 X-RAY
 2011-04-13 LEU A:293 A:293 0.0 0.0 E -114.2 112.9 0.0 0.0 0.0 CL
PCA
HOH
 6.058
9.305
5.740
 CD1
CD2
O
 CL
O
O
6z8l 1 P04746 97.18 0.0 X-RAY
 2020-12-02 LEU A:293 A:293 0.0 0.0 E -105.4 115.3 0.0 0.0 0.0 CL
HOH
 5.303
5.582
 HD12
O
 CL
O
1b2y 1 P04746 97.18 0.0 X-RAY
 2000-02-16 LEU A:293 A:293 0.0 0.0 E -125.6 110.1 0.0 0.0 0.0 CL
PCA
HOH
 6.155
9.282
5.427
 CD1
CD2
O
 CL
O
O
1bsi 1 P04746 96.98 0.0 X-RAY
 1999-05-18 LEU A:293 A:293 0.0 0.0 E -114.2 113.3 0.0 0.0 0.0 CL
HOH
 5.887
5.899
 CD1
O
 CL
O
1cpu 1 P04746 96.98 0.0 X-RAY
 1999-06-14 LEU A:293 A:293 0.0 0.0 E -112.8 112.9 0.0 0.0 0.0 CL
HOH
 6.168
5.774
 CD1
O
 CL
O
1hny 1 P04746 96.98 0.0 X-RAY
 1996-03-08 LEU A:293 A:293 0.0 0.0 E -124.1 112.6 0.0 0.0 0.0 CL
HOH
 6.135
5.900
 CD1
O
 CL
O
1u2y 1 P04746 96.98 0.0 X-RAY
 2004-09-07 LEU A:293 A:293 0.0 0.0 E -117.1 114.7 0.0 0.0 0.0 CL
HOH
 6.036
5.854
 CD1
O
 CL
O
1u30 1 P04746 96.98 0.0 X-RAY
 2004-09-07 LEU A:293 A:293 0.0 0.0 E -114.1 112.1 0.0 0.0 0.0 CL
HOH
 5.863
5.745
 CD1
O
 CL
O
1u33 1 P04746 96.98 0.0 X-RAY
 2004-09-07 LEU A:293 A:293 0.0 0.0 E -117.5 110.3 0.0 0.0 0.0 CL
HOH
 6.021
5.723
 CD1
O
 CL
O
1xcw 1 P04746 96.98 0.0 X-RAY
 2004-12-07 LEU A:293 A:293 0.0 0.0 E -119.5 117.0 0.0 0.0 0.0 CL
HOH
 6.069
5.853
 CD1
O
 CL
O
1xcx 1 P04746 96.98 0.0 X-RAY
 2004-12-07 LEU A:293 A:293 0.0 0.0 E -117.6 112.7 0.0 0.0 0.0 CL
HOH
 5.981
5.867
 CD1
O
 CL
O
1xd0 1 P04746 96.98 0.0 X-RAY
 2004-12-07 LEU A:293 A:293 0.0 0.0 E -118.2 116.9 0.0 0.0 0.0 CL
HOH
 6.256
5.833
 CD1
O
 CL
O
1xd1 1 P04746 96.98 0.0 X-RAY
 2004-12-07 LEU A:293 A:293 0.0 0.0 E -115.5 114.9 0.0 0.0 0.0 CL
HOH
 5.883
5.964
 CD1
O
 CL
O
2qmk 1 P04746 96.98 0.0 X-RAY
 2008-03-25 LEU A:293 A:293 0.0 0.0 E -106.9 108.1 0.0 0.0 0.0 NO2
HOH
 5.069
5.709
 CD1
O
 O2
O
2qv4 1 P04746 96.98 0.0 X-RAY
 2008-03-25 LEU A:293 A:293 0.0 0.0 E -111.8 111.5 0.0 0.0 0.0 NO2
HOH
 5.257
5.757
 CD1
O
 O2
O
3bai 1 P04746 96.98 0.0 X-RAY
 2008-03-25 LEU A:293 A:293 0.0 0.0 E -114.1 116.3 0.0 0.0 0.0 NO3
HOH
 5.192
5.760
 CD1
O
 O2
O
3baj 1 P04746 96.98 0.0 X-RAY
 2008-03-25 LEU A:293 A:293 0.0 0.0 E -111.7 114.5 0.0 0.0 0.0 NO3
HOH
 5.271
5.796
 CD1
O
 O2
O
3baw 1 P04746 96.98 0.0 X-RAY
 2008-03-25 LEU A:293 A:293 0.0 0.0 E -113.0 108.5 0.0 0.0 0.0 CL
HOH
 5.964
5.797
 CD1
O
 CL
O
3ij7 1 P04746 96.98 0.0 X-RAY
 2009-10-27 LEU A:293 A:293 0.0 0.0 E -112.2 107.1 0.0 0.0 0.0 CL
HOH
 5.826
5.665
 CD1
O
 CL
O
3ij8 1 P04746 96.98 0.0 X-RAY
 2009-10-27 LEU A:293 A:293 0.0 0.0 E -112.3 109.6 0.0 0.0 0.0 CL
HOH
 5.947
5.656
 CD1
O
 CL
O
3ij9 1 P04746 96.98 0.0 X-RAY
 2009-10-27 LEU A:293 A:293 0.0 0.0 E -111.7 108.2 0.0 0.0 0.0 CL
HOH
 5.858
5.705
 CD1
O
 CL
O
4gqq 1 P04746 96.98 0.0 X-RAY
 2012-10-24 LEU A:293 A:293 0.0 0.0 E -113.4 117.2 0.0 0.0 0.0 CL
HOH
 5.788
5.452
 CD1
O
 CL
O
4gqr 1 P04746 96.98 0.0 X-RAY
 2012-10-24 LEU A:293 A:293 0.0 0.0 E -112.4 111.6 0.0 0.0 0.0 CL
HOH
 5.977
5.585
 CD1
O
 CL
O
4w93 1 P04746 96.98 0.0 X-RAY
 2015-07-15 LEU A:293 A:293 0.0 0.0 E -107.4 118.5 0.0 0.0 0.0 CL
HOH
 5.963
5.687
 CD1
O
 CL
O
4x9y 1 P04746 96.98 0.0 X-RAY
 2014-12-31 LEU A:293 A:293 0.0 0.0 E -109.1 116.6 0.0 0.0 0.0 CL
HOH
 5.150
5.693
 HD12
O
 CL
O
5e0f 1 P04746 96.98 0.0 X-RAY
 2016-09-07 LEU A:293 A:293 0.0 0.0 E -109.4 115.7 0.0 0.0 0.0 CL
HOH
 5.161
5.681
 HD12
O
 CL
O
5emy 1 P04746 96.98 0.0 X-RAY
 2016-07-06 LEU A:293 A:293 0.0 0.0 E -107.9 116.0 0.0 0.0 0.0 CL
HOH
 5.070
5.676
 HD12
O
 CL
O
5kez 1 P04746 96.98 0.0 X-RAY
 2017-03-29 LEU A:293 A:293 0.0 0.0 E -106.9 117.7 0.0 0.0 0.0 CL
HOH
 6.209
5.802
 CD1
O
 CL
O
5u3a 1 P04746 96.98 0.0 X-RAY
 2017-12-06 LEU A:293 A:293 0.0 0.0 E -108.8 116.6 0.0 0.0 0.0 CL
HOH
 5.153
5.662
 HD12
O
 CL
O
5va9 1 P04746 96.98 0.0 X-RAY
 2018-03-28 LEU A:293 A:293 0.0 0.0 E -106.2 116.1 0.0 0.0 0.0 CL
HOH
 5.990
5.682
 CD1
O
 CL
O
LEU B:293 B:293 0.0 0.0 E -104.3 115.7 NA NA NA
6obx 1 P04746 96.98 0.0 X-RAY
 2020-02-12 LEU A:293 A:293 0.0 0.0 E -109.5 116.4 0.0 0.0 0.0 CL
HOH
 5.191
5.682
 HD12
O
 CL
O
6ocn 1 P04746 96.98 0.0 X-RAY
 2020-02-12 LEU A:293 A:293 0.0 0.0 E -109.1 117.9 0.0 0.0 0.0 CL
HOH
 5.174
5.683
 HD12
O
 CL
O
1kgw 1 P04746 96.77 0.0 X-RAY
 2002-01-16 LEU A:293 A:293 0.0 0.0 E -118.3 109.4 0.0 0.0 0.0 HOH
 4.301
 CD1
 O
1xgz 1 P04746 96.77 0.0 X-RAY
 2005-05-24 LEU A:293 A:293 0.0 0.0 E -120.0 114.1 0.0 0.0 0.0 HOH
 5.746
 O
 O
1xh0 1 P04746 96.77 0.0 X-RAY
 2005-05-24 LEU A:293 A:293 0.0 0.0 E -119.2 110.6 0.0 0.0 0.0 HOH
 5.816
 O
 O
1xh1 1 P04746 96.77 0.0 X-RAY
 2005-05-24 LEU A:293 A:293 0.0 0.0 E -113.2 112.3 0.0 0.0 0.0 CL
HOH
 6.239
5.749
 CD1
O
 CL
O
1xh2 1 P04746 96.77 0.0 X-RAY
 2005-05-24 LEU A:293 A:293 0.0 0.0 E -108.1 116.5 0.0 0.0 0.0 CL
HOH
 6.151
5.813
 CD1
O
 CL
O
3bak 1 P04746 96.77 0.0 X-RAY
 2008-03-25 LEU A:293 A:293 0.0 0.0 E -115.2 113.4 0.0 0.0 0.0 NO3
HOH
 5.274
5.729
 CD1
O
 O2
O
3bax 1 P04746 96.77 0.0 X-RAY
 2008-03-25 LEU A:293 A:293 0.0 0.0 E -112.3 112.8 0.0 0.0 0.0 CL
HOH
 6.154
5.702
 CD1
O
 CL
O
3bay 1 P04746 96.77 0.0 X-RAY
 2008-03-25 LEU A:293 A:293 0.0 0.0 E -115.4 114.0 0.0 0.0 0.0 NO3
HOH
 5.714
5.714
 CD1
O
 O3
O
1kgx 1 P04746 96.77 0.0 X-RAY
 2002-01-16 LEU A:293 A:293 0.0 0.0 E -116.5 109.6 0.0 0.0 0.0 HOH
 5.816
 O
 O
2cpu 1 P04746 96.77 0.0 X-RAY
 2001-06-30 LEU A:293 A:293 0.0 0.0 E -112.4 111.7 0.0 0.0 0.0 CL
HOH
 5.910
5.755
 CD1
O
 CL
O
3cpu 1 P04746 96.77 0.0 X-RAY
 2001-06-30 LEU A:293 A:293 0.0 0.0 E -115.1 108.8 0.0 0.0 0.0 CL
HOH
 5.969
2.676
 CD1
CD2
 CL
O
5td4 1 P04746 96.77 0.0 X-RAY
 2016-11-02 LEU A:293 A:293 0.0 0.0 E -101.4 114.9 0.0 0.0 0.0 CL
HOH
 5.901
5.680
 CD1
O
 CL
O
1kgu 1 P04746 96.77 0.0 X-RAY
 2002-01-16 LEU A:293 A:293 4.0 0.024 E -116.3 111.1 4.0 0.024 0.0 HOH
 4.545
 CD1
 O
1kb3 1 P04746 96.77 0.0 X-RAY
 2002-05-01 LEU A:293 A:293 0.0 0.0 E -117.3 103.2 0.0 0.0 0.0 HOH
 5.541
 O
 O
1kbb 1 P04746 96.77 0.0 X-RAY
 2002-04-10 LEU A:293 A:293 0.0 0.0 E -122.2 113.8 0.0 0.0 0.0 CL
HOH
 6.088
5.893
 CD1
O
 CL
O
1kbk 1 P04746 96.77 0.0 X-RAY
 2002-04-10 LEU A:293 A:293 0.0 0.0 E -116.4 116.7 0.0 0.0 0.0 CL
HOH
 6.077
5.854
 CD1
O
 CL
O
1kxq 1 P00690 86.29 0.0 X-RAY
 2002-06-19 LEU A:293 A:293 0.0 0.0 E -112.4 117.9 0.0 0.0 0.0 CL
HOH
 5.804
5.556
 CD2
O
 CL
O
LEU B:293 B:293 0.0 0.0 E -114.7 118.5 NA NA NA
LEU C:293 C:293 0.0 0.0 E -116.5 118.0 NA NA NA
LEU D:293 D:293 0.0 0.0 E -114.1 115.7 NA NA NA
1kxt 1 P00690 86.29 0.0 X-RAY
 2002-06-19 LEU A:293 A:293 0.0 0.0 E -118.6 112.5 0.0 0.0 0.0 CL
HOH
 5.769
5.891
 CD2
O
 CL
O
LEU C:293 C:293 0.0 0.0 E -124.7 110.6 NA NA NA
LEU E:293 E:293 0.0 0.0 E -120.8 115.9 NA NA NA
1kxv 1 P00690 86.29 0.0 X-RAY
 2002-06-19 LEU A:293 A:293 0.0 0.0 E -111.9 118.3 0.0 0.0 0.0 HOH
 5.760
 O
 O
LEU B:293 B:293 0.0 0.0 E -112.7 116.0 NA NA NA
1dhk 1 P00690 86.29 0.0 X-RAY
 1997-12-24 LEU A:293 A:293 0.0 0.0 E -116.1 120.6 0.0 0.0 0.0 CL
HOH
 5.782
5.051
 CD2
O
 CL
H1
1ppi 1 P00690 86.29 0.0 X-RAY
 1995-05-24 LEU A:293 A:293 0.0 0.0 E -106.4 129.2 0.0 0.0 0.0 CL
HOH
 6.125
5.632
 CD2
O
 CL
O
1vah 1 P00690 86.09 0.0 X-RAY
 2005-04-26 LEU A:293 A:293 0.0 0.0 E -124.2 115.7 0.0 0.0 0.0 CL
HOH
 5.568
6.767
 CD2
CD2
 CL
O
3l2l 1 P00690 86.09 0.0 X-RAY
 2010-04-14 LEU A:293 A:293 0.0 0.0 E -105.9 124.2 0.0 0.0 0.0 CL
HOH
 5.413
5.668
 HD21
O
 CL
O
3l2m 1 P00690 86.09 0.0 X-RAY
 2010-04-14 LEU A:293 A:293 0.0 0.0 E -110.1 122.2 0.0 0.0 0.0 CL
HOH
 5.404
5.571
 HD21
O
 CL
O
1ua3 1 P00690 86.09 0.0 X-RAY
 2003-10-14 LEU A:293 A:293 0.0 0.0 E -102.6 120.3 0.0 0.0 0.0 CL
HOH
 6.070
5.578
 CD1
O
 CL
O
1ose 1 P00690 85.89 0.0 X-RAY
 1997-04-01 LEU A:293 A:293 0.0 0.0 E -118.2 116.6 0.0 0.0 0.0 CL
HOH
 5.691
5.944
 CD2
O
 CL
O
1jfh 1 P00690 86.09 0.0 X-RAY
 1998-12-02 LEU A:293 A:293 0.0 0.0 E -117.8 116.4 0.0 0.0 0.0 CL
HOH
 5.661
5.583
 CD2
O
 CL
O
1hx0 1 P00690 85.89 0.0 X-RAY
 2001-08-08 LEU A:293 A:293 0.0 0.0 E -109.7 120.8 0.0 0.0 0.0 CL
HOH
 6.008
5.758
 CD1
O
 CL
O
1wo2 1 P00690 85.89 0.0 X-RAY
 2005-03-15 LEU A:293 A:293 0.0 0.0 E -117.9 111.8 0.0 0.0 0.0 CL
HOH
 5.894
5.585
 CD2
O
 CL
O
1pif 1 P00690 85.69 0.0 X-RAY
 1996-12-07 LEU A:293 A:293 0.0 0.0 E -118.6 118.9 0.0 0.0 0.0 CL
HOH
 5.721
5.587
 CD2
O
 CL
O
1pig 1 P00690 85.69 0.0 X-RAY
 1996-12-07 LEU A:293 A:293 0.0 0.0 E -115.7 120.0 0.0 0.0 0.0 CL
HOH
 5.730
4.657
 CD2
CD2
 CL
O
4x0n 1 P00690 85.69 0.0 X-RAY
 2015-11-25 LEU A:293 A:293 0.0 0.0 E -109.8 121.0 0.0 0.0 0.0 CL
HOH
 5.561
5.744
 CD2
O
 CL
O
1bvn 1 P00690 85.48 0.0 X-RAY
 1998-09-23 LEU A:293 P:293 0.0 0.0 E -101.0 123.7 0.0 0.0 0.0 CL
HOH
 5.277
5.770
 CD2
O
 CL
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p0dte7-f1 1 P0DTE7 100.0 0.0 LEU A:308 A:308 0.0 0.0 E -104.5 118.3
af-p0dte8-f1 1 P0DTE8 100.0 0.0 LEU A:308 A:308 0.0 0.0 E -104.5 118.7
af-p0dub6-f1 1 P0DUB6 100.0 0.0 LEU A:308 A:308 0.0 0.0 E -103.7 117.8
af-p19961-f1 1 P19961 97.46 0.0 LEU A:308 A:308 0.0 0.0 E -104.3 117.6
af-p04746-f1 1 P04746 96.87 0.0 LEU A:308 A:308 0.0 0.0 E -106.5 117.9