Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 104297349 . G A CCDS30784.1:NM_001008219.1:c.1014atG>atA_NP_001008220.1:p.338M>I Homo sapiens amylase, alpha 1C (salivary) (AMY1C), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1c8q 1 P04745 99.8 0.0 X-RAY
 2001-06-13 MET A:323 A:323 0.0 0.0 H -69.6 -43.6 0.0 0.0 0.0 HOH
 3.411
 CG
 O
1mfv 1 P04745 99.8 0.0 X-RAY
 2002-11-20 MET A:323 A:323 0.0 0.0 H -68.6 -44.6 0.0 0.0 0.0 HOH
 3.479
 CG
 O
1smd 1 P04745 99.8 0.0 X-RAY
 1996-07-11 MET A:323 A:323 0.0 0.0 H -64.5 -47.9 0.0 0.0 0.0 HOH
 3.747
 CG
 O
1xv8 1 P04745 99.8 0.0 X-RAY
 2005-10-11 MET A:323 A:323 0.0 0.0 H -65.2 -54.7 0.0 0.0 0.0 HOH
 5.351
 CE
 O
MET B:323 B:323 0.0 0.0 H -65.2 -54.7 0.0 0.0 0.0 HOH
 5.351
 CE
 O
1q4n 1 P04745 99.6 0.0 X-RAY
 2004-03-16 MET A:323 X:323 0.0 0.0 H -67.2 -42.4 0.0 0.0 0.0 HOH
 3.575
 CG
 O
1z32 1 P04745 99.6 0.0 X-RAY
 2005-05-31 MET A:323 X:323 0.0 0.0 H -65.0 -45.4 0.0 0.0 0.0 HOH
 2.381
 CG
 O
1jxj 1 P04745 99.6 0.0 X-RAY
 2001-09-14 MET A:323 A:323 0.0 0.0 H -66.6 -45.2 0.0 0.0 0.0 HOH
 3.367
 CG
 O
1nm9 1 P04745 99.6 0.0 X-RAY
 2004-01-20 MET A:323 A:323 0.0 0.0 H -68.1 -45.1 0.0 0.0 0.0 HOH
 3.398
 CG
 O
3blk 1 P04745 99.6 0.0 X-RAY
 2008-11-25 MET A:323 A:323 1.0 0.005 H -67.8 -46.1 1.0 0.005 0.0 HOH
 3.739
 CG
 O
3blp 1 P04745 99.6 0.0 X-RAY
 2008-11-18 MET A:323 X:323 0.0 0.0 H -64.8 -45.8 0.0 0.0 0.0 HOH
 3.453
 CG
 O
1jxk 1 P04745 98.79 0.0 X-RAY
 2001-09-14 MET A:318 A:318 0.0 0.0 H -63.3 -44.8 0.0 0.0 0.0 HOH
 3.368
 CG
 O
1mfu 1 P04745 98.79 0.0 X-RAY
 2002-11-20 MET A:318 A:318 0.0 0.0 H -69.2 -46.9 0.0 0.0 0.0 GLC
HOH
 9.453
3.514
 N
CG
 O2
O
3dhp 1 P04745 98.59 0.0 X-RAY
 2008-07-01 MET A:323 A:323 0.0 0.0 H -68.7 -42.6 0.0 0.0 0.0 HOH
 3.985
 N
 O
3old 1 P04746 97.38 0.0 X-RAY
 2011-04-13 MET A:323 A:323 0.0 0.0 H -71.8 -40.7 0.0 0.0 0.0 GLC
HOH
 8.983
5.217
 N
N
 O2
O
3ole 1 P04746 97.38 0.0 X-RAY
 2011-04-13 MET A:323 A:323 0.0 0.0 H -69.8 -39.7 0.0 0.0 0.0 GLC
HOH
 9.046
4.084
 N
N
 O2
O
3olg 1 P04746 97.38 0.0 X-RAY
 2011-04-13 MET A:323 A:323 0.0 0.0 H -63.7 -46.8 0.0 0.0 0.0 GLC
HOH
 9.098
4.090
 N
CE
 O2
O
3oli 1 P04746 97.38 0.0 X-RAY
 2011-04-13 MET A:323 A:323 0.0 0.0 H -68.2 -43.3 0.0 0.0 0.0 BGC
HOH
 9.278
4.053
 N
N
 O2
O
6z8l 1 P04746 97.18 0.0 X-RAY
 2020-12-02 MET A:323 A:323 0.0 0.0 H -65.6 -45.7 0.0 0.0 0.0 HOH
 2.665
 HG3
 O
1b2y 1 P04746 97.18 0.0 X-RAY
 2000-02-16 MET A:323 A:323 0.0 0.0 H -66.9 -44.4 0.0 0.0 0.0 HOH
 5.898
 CE
 O
1bsi 1 P04746 96.98 0.0 X-RAY
 1999-05-18 MET A:323 A:323 0.0 0.0 H -68.0 -39.9 0.0 0.0 0.0 HOH
 4.136
 N
 O
1cpu 1 P04746 96.98 0.0 X-RAY
 1999-06-14 MET A:323 A:323 0.0 0.0 H -67.9 -41.9 0.0 0.0 0.0 HOH
 4.130
 CG
 O
1hny 1 P04746 96.98 0.0 X-RAY
 1996-03-08 MET A:323 A:323 0.0 0.0 H -60.8 -50.6 0.0 0.0 0.0 HOH
 3.905
 CG
 O
1u2y 1 P04746 96.98 0.0 X-RAY
 2004-09-07 MET A:323 A:323 0.0 0.0 H -70.0 -43.0 0.0 0.0 0.0 HOH
 4.167
 N
 O
1u30 1 P04746 96.98 0.0 X-RAY
 2004-09-07 MET A:323 A:323 0.0 0.0 H -70.3 -39.8 0.0 0.0 0.0 HOH
 3.619
 CG
 O
1u33 1 P04746 96.98 0.0 X-RAY
 2004-09-07 MET A:323 A:323 0.0 0.0 H -71.2 -44.4 0.0 0.0 0.0 HOH
 3.922
 CG
 O
1xcw 1 P04746 96.98 0.0 X-RAY
 2004-12-07 MET A:323 A:323 0.0 0.0 H -69.3 -40.3 0.0 0.0 0.0 HOH
 4.105
 N
 O
1xcx 1 P04746 96.98 0.0 X-RAY
 2004-12-07 MET A:323 A:323 1.0 0.005 H -70.5 -40.5 1.0 0.005 0.0 HOH
 4.272
 N
 O
1xd0 1 P04746 96.98 0.0 X-RAY
 2004-12-07 MET A:323 A:323 1.0 0.005 H -67.5 -39.9 1.0 0.005 0.0 HOH
 3.813
 CG
 O
1xd1 1 P04746 96.98 0.0 X-RAY
 2004-12-07 MET A:323 A:323 0.0 0.0 H -69.6 -40.6 0.0 0.0 0.0 HOH
 4.138
 N
 O
2qmk 1 P04746 96.98 0.0 X-RAY
 2008-03-25 MET A:323 A:323 1.0 0.005 H -69.7 -41.2 1.0 0.005 0.0 HOH
 4.019
 N
 O
2qv4 1 P04746 96.98 0.0 X-RAY
 2008-03-25 MET A:323 A:323 0.0 0.0 H -62.9 -48.4 0.0 0.0 0.0 HOH
 2.925
 CE
 O
3bai 1 P04746 96.98 0.0 X-RAY
 2008-03-25 MET A:323 A:323 1.0 0.005 H -68.8 -39.6 1.0 0.005 0.0 HOH
 4.163
 N
 O
3baj 1 P04746 96.98 0.0 X-RAY
 2008-03-25 MET A:323 A:323 1.0 0.005 H -67.9 -39.9 1.0 0.005 0.0 HOH
 5.850
 CE
 O
3baw 1 P04746 96.98 0.0 X-RAY
 2008-03-25 MET A:323 A:323 0.0 0.0 H -71.4 -40.3 0.0 0.0 0.0 HOH
 3.966
 N
 O
3ij7 1 P04746 96.98 0.0 X-RAY
 2009-10-27 MET A:323 A:323 0.0 0.0 H -71.4 -42.0 0.0 0.0 0.0 GLF
HOH
 8.934
4.185
 N
N
 O2
O
3ij8 1 P04746 96.98 0.0 X-RAY
 2009-10-27 MET A:323 A:323 0.0 0.0 H -66.3 -44.4 0.0 0.0 0.0 HOH
 4.000
 N
 O
3ij9 1 P04746 96.98 0.0 X-RAY
 2009-10-27 MET A:323 A:323 0.0 0.0 H -68.3 -43.7 0.0 0.0 0.0 HOH
 3.985
 N
 O
4gqq 1 P04746 96.98 0.0 X-RAY
 2012-10-24 MET A:323 A:323 0.0 0.0 H -67.8 -40.8 0.0 0.0 0.0 HOH
 3.381
 CG
 O
4gqr 1 P04746 96.98 0.0 X-RAY
 2012-10-24 MET A:323 A:323 0.0 0.0 H -67.2 -43.5 0.0 0.0 0.0 HOH
 3.848
 CG
 O
4w93 1 P04746 96.98 0.0 X-RAY
 2015-07-15 MET A:323 A:323 0.0 0.0 H -67.0 -47.0 0.0 0.0 0.0 HOH
 3.666
 CG
 O
4x9y 1 P04746 96.98 0.0 X-RAY
 2014-12-31 MET A:323 A:323 0.0 0.0 H -62.5 -46.1 0.0 0.0 0.0 HOH
 3.117
 HG3
 O
5e0f 1 P04746 96.98 0.0 X-RAY
 2016-09-07 MET A:323 A:323 0.0 0.0 H -66.2 -43.6 0.0 0.0 0.0 HOH
 5.251
 HA
 O
5emy 1 P04746 96.98 0.0 X-RAY
 2016-07-06 MET A:323 A:323 0.0 0.0 H -62.4 -47.7 0.0 0.0 0.0 HOH
 2.917
 HG2
 O
5kez 1 P04746 96.98 0.0 X-RAY
 2017-03-29 MET A:323 A:323 0.0 0.0 H -61.5 -46.1 0.0 0.0 0.0 HOH
 3.830
 CG
 O
5u3a 1 P04746 96.98 0.0 X-RAY
 2017-12-06 MET A:323 A:323 0.0 0.0 H -62.4 -46.1 0.0 0.0 0.0 HOH
 2.988
 HG2
 O
5va9 1 P04746 96.98 0.0 X-RAY
 2018-03-28 MET A:323 A:323 0.0 0.0 H -67.2 -43.8 0.0 0.0 0.0 HOH
 3.712
 CG
 O
MET B:323 B:323 0.0 0.0 H -67.3 -44.4 NA NA NA
6obx 1 P04746 96.98 0.0 X-RAY
 2020-02-12 MET A:323 A:323 1.0 0.005 H -66.2 -43.5 1.0 0.005 0.0 HOH
 3.498
 HB2
 O
6ocn 1 P04746 96.98 0.0 X-RAY
 2020-02-12 MET A:323 A:323 0.0 0.0 H -58.8 -49.9 0.0 0.0 0.0 HOH
 2.841
 HG3
 O
1kgw 1 P04746 96.77 0.0 X-RAY
 2002-01-16 MET A:323 A:323 2.0 0.011 H -65.5 -45.9 2.0 0.011 0.0 HOH
 3.682
 CG
 O
1xgz 1 P04746 96.77 0.0 X-RAY
 2005-05-24 MET A:323 A:323 0.0 0.0 H -68.5 -39.7 0.0 0.0 0.0 HOH
 3.899
 N
 O
1xh0 1 P04746 96.77 0.0 X-RAY
 2005-05-24 MET A:323 A:323 1.0 0.005 H -67.1 -41.1 1.0 0.005 0.0 HOH
 3.870
 N
 O
1xh1 1 P04746 96.77 0.0 X-RAY
 2005-05-24 MET A:323 A:323 0.0 0.0 H -66.4 -46.9 0.0 0.0 0.0 HOH
 4.158
 N
 O
1xh2 1 P04746 96.77 0.0 X-RAY
 2005-05-24 MET A:323 A:323 1.0 0.005 H -67.3 -43.7 1.0 0.005 0.0 HOH
 4.256
 N
 O
3bak 1 P04746 96.77 0.0 X-RAY
 2008-03-25 MET A:323 A:323 0.0 0.0 H -68.9 -37.2 0.0 0.0 0.0 HOH
 4.160
 N
 O
3bax 1 P04746 96.77 0.0 X-RAY
 2008-03-25 MET A:323 A:323 0.0 0.0 H -70.5 -39.1 0.0 0.0 0.0 HOH
 3.971
 N
 O
3bay 1 P04746 96.77 0.0 X-RAY
 2008-03-25 MET A:323 A:323 1.0 0.005 H -63.3 -39.0 1.0 0.005 0.0 HOH
 3.951
 N
 O
1kgx 1 P04746 96.77 0.0 X-RAY
 2002-01-16 MET A:323 A:323 0.0 0.0 H -70.1 -42.7 0.0 0.0 0.0 HOH
 2.956
 O
 O
2cpu 1 P04746 96.77 0.0 X-RAY
 2001-06-30 MET A:323 A:323 0.0 0.0 H -67.9 -41.0 0.0 0.0 0.0 HOH
 4.165
 N
 O
3cpu 1 P04746 96.77 0.0 X-RAY
 2001-06-30 MET A:323 A:323 0.0 0.0 H -74.7 -39.5 0.0 0.0 0.0 HOH
 4.145
 CB
 O
5td4 1 P04746 96.77 0.0 X-RAY
 2016-11-02 MET A:323 A:323 0.0 0.0 H -68.8 -43.8 0.0 0.0 0.0 HOH
 3.763
 CG
 O
1kgu 1 P04746 96.77 0.0 X-RAY
 2002-01-16 MET A:323 A:323 0.0 0.0 H -69.4 -43.4 0.0 0.0 0.0 HOH
 4.110
 N
 O
1kb3 1 P04746 96.77 0.0 X-RAY
 2002-05-01 MET A:323 A:323 0.0 0.0 H -69.3 -39.4 0.0 0.0 0.0 HOH
 4.056
 N
 O
1kbb 1 P04746 96.77 0.0 X-RAY
 2002-04-10 MET A:323 A:323 0.0 0.0 H -66.1 -48.7 0.0 0.0 0.0 HOH
 4.091
 CG
 O
1kbk 1 P04746 96.77 0.0 X-RAY
 2002-04-10 MET A:323 A:323 1.0 0.005 H -67.8 -44.1 1.0 0.005 0.0 HOH
 3.801
 CG
 O
1kxq 1 P00690 86.29 0.0 X-RAY
 2002-06-19 ILE A:323 A:323 1.0 0.006 H -66.7 -41.3 1.0 0.006 0.0 HOH
 3.791
 CG1
 O
ILE B:323 B:323 1.0 0.006 H -67.6 -42.1 NA NA NA
ILE C:323 C:323 1.0 0.006 H -70.4 -40.4 NA NA NA
ILE D:323 D:323 1.0 0.006 H -66.2 -44.7 NA NA NA
1kxt 1 P00690 86.29 0.0 X-RAY
 2002-06-19 ILE A:323 A:323 0.0 0.0 H -66.0 -41.6 0.0 0.0 0.0 HOH
 2.440
 CA
 O
ILE C:323 C:323 2.0 0.011 H -70.2 -44.6 NA NA NA
ILE E:323 E:323 2.0 0.011 H -69.8 -39.2 NA NA NA
1kxv 1 P00690 86.29 0.0 X-RAY
 2002-06-19 ILE A:323 A:323 1.0 0.006 H -70.2 -36.7 1.0 0.006 0.0 HOH
 3.616
 CG1
 O
ILE B:323 B:323 7.0 0.04 H -66.5 -42.0 NA NA NA
1dhk 1 P00690 86.29 0.0 X-RAY
 1997-12-24 VAL A:323 A:323 4.0 0.026 H -65.7 -46.0 4.0 0.026 0.0 HOH
 2.587
 CG2
 H2
1ppi 1 P00690 86.29 0.0 X-RAY
 1995-05-24 VAL A:323 A:323 5.0 0.032 H -74.1 -31.9 5.0 0.032 0.0 HOH
 3.528
 CG1
 O
1vah 1 P00690 86.09 0.0 X-RAY
 2005-04-26 ILE A:323 A:323 0.0 0.0 H -61.1 -49.5 0.0 0.0 0.0 HOH
 7.976
 CG1
 O
3l2l 1 P00690 86.09 0.0 X-RAY
 2010-04-14 VAL A:323 A:323 2.0 0.013 H -59.4 -50.0 2.0 0.013 0.0 HOH
 2.847
 HG23
 O
3l2m 1 P00690 86.09 0.0 X-RAY
 2010-04-14 VAL A:323 A:323 2.0 0.013 H -58.5 -49.5 2.0 0.013 0.0 HOH
 2.990
 HG23
 O
1ua3 1 P00690 86.09 0.0 X-RAY
 2003-10-14 ILE A:323 A:323 1.0 0.006 H -62.0 -47.6 1.0 0.006 0.0 GLC
HOH
 9.343
3.853
 N
CG1
 O3
O
1ose 1 P00690 85.89 0.0 X-RAY
 1997-04-01 VAL A:323 A:323 3.0 0.019 H -72.4 -34.7 3.0 0.019 0.0 HOH
 3.563
 CG1
 O
1jfh 1 P00690 86.09 0.0 X-RAY
 1998-12-02 ILE A:323 A:323 1.0 0.006 H -67.9 -46.2 1.0 0.006 0.0 MA1
HOH
 9.138
3.752
 N
CG1
 O2
O
1hx0 1 P00690 85.89 0.0 X-RAY
 2001-08-08 ILE A:323 A:323 1.0 0.006 H -61.5 -44.3 1.0 0.006 0.0 EDO
EDO
HOH
 9.435
7.688
3.725
 N
CG1
CG1
 C2
O2
O
1wo2 1 P00690 85.89 0.0 X-RAY
 2005-03-15 ILE A:323 A:323 1.0 0.006 H -66.4 -46.4 1.0 0.006 0.0 BGC
HOH
 9.316
3.757
 N
CG1
 O2
O
1pif 1 P00690 85.69 0.0 X-RAY
 1996-12-07 VAL A:323 A:323 3.0 0.019 H -67.2 -45.5 3.0 0.019 0.0 HOH
 3.701
 CG2
 O
1pig 1 P00690 85.69 0.0 X-RAY
 1996-12-07 VAL A:323 A:323 2.0 0.013 H -65.6 -47.9 2.0 0.013 0.0 GLC
HOH
 9.005
3.794
 N
CG2
 O2
O
4x0n 1 P00690 85.69 0.0 X-RAY
 2015-11-25 VAL A:323 A:323 3.0 0.019 H -58.3 -49.1 3.0 0.019 0.0 HOH
 3.778
 CG2
 O
1bvn 1 P00690 85.48 0.0 X-RAY
 1998-09-23 VAL A:323 P:323 2.0 0.013 H -67.0 -31.2 2.0 0.013 0.0 HOH
 3.444
 CG2
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p0dte7-f1 1 P0DTE7 100.0 0.0 MET A:338 A:338 0.0 0.0 H -65.5 -45.3
af-p0dte8-f1 1 P0DTE8 100.0 0.0 MET A:338 A:338 0.0 0.0 H -65.3 -45.5
af-p0dub6-f1 1 P0DUB6 100.0 0.0 MET A:338 A:338 0.0 0.0 H -65.4 -45.5
af-p19961-f1 1 P19961 97.46 0.0 MET A:338 A:338 0.0 0.0 H -65.5 -45.4
af-p04746-f1 1 P04746 96.87 0.0 MET A:338 A:338 0.0 0.0 H -65.7 -46.6