Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 115828756 . G A CCDS882.1:NM_002506.2:c.661Cgg>Tgg_NP_002497.2:p.221R>W Homo sapiens nerve growth factor (NGF), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6xuo 1 F6SVV7 94.62 8e-146 X-RAY
 2020-01-29 ARG A:204 A:100 86.0 0.382 E -132.1 162.1 86.0 0.382 0.0
3ij2 1 P01139 82.19 2e-135 X-RAY
 2010-01-12 ARG A:203 A:100 74.0 0.329 E -146.5 166.9 20.0 0.089 0.24 B:P07174:0.24
ARG C:203 B:100 75.0 0.333 E -145.5 167.3 18.0 0.08 0.253 D:P07174:0.253
1sg1 1 P01138 100.0 1e-87 X-RAY
 2004-06-01 ARG A:100 A:100 64.0 0.284 E -138.9 168.4 6.0 0.027 0.257 C:P07174:0.258
 HOH
 3.126
 CA
 O
ARG B:100 B:100 36.0 0.16 E -139.8 160.9 36.0 0.16 0.0 HOH
 3.851
 CB
 O
1www 1 P01138 100.0 1e-87 X-RAY
 1999-09-15 ARG A:100 V:100 93.0 0.413 E -135.7 152.9 93.0 0.413 0.0 HOH
 3.769
 CB
 O
ARG B:100 W:100 101.0 0.449 E -115.6 154.4 101.0 0.449 0.0 HOH
 3.267
 CB
 O
2ifg 2 P01138 100.0 1e-87 X-RAY
 2007-02-13 ARG C:100 E:100 82.0 0.364 E -135.7 152.8 82.0 0.364 0.0
ARG D:100 F:100 98.0 0.436 E -115.5 154.4 98.0 0.436 0.0
4edw 1 P01138 100.0 1e-87 X-RAY
 2014-04-02 ARG A:100 V:100 69.0 0.307 E -123.7 157.5 69.0 0.307 0.0
4edx 1 P01138 100.0 1e-87 X-RAY
 2014-04-02 ARG A:100 W:100 46.0 0.204 E -120.0 146.6 46.0 0.204 0.0 HOH
 8.160
 NH1
 O
ARG D:100 V:100 45.0 0.2 E -119.9 145.9 45.0 0.2 0.0 HOH
 3.420
 CA
 O
4zbn 2 P01138 100.0 1e-87 X-RAY
 2015-06-10 ARG C:100 A:100 53.0 0.236 E -119.3 150.2 53.0 0.236 0.0 DUZ
DUZ
DUZ
DA
HOH
 8.888
5.785
7.140
9.252
3.462
 CA
CD
NH2
NH2
CA
 O3'
O4'
OP1
OP1
O
ARG D:100 B:100 89.0 0.396 E -130.8 154.5 89.0 0.396 0.0 DUZ
DUZ
DUZ
DA
HOH
 8.707
4.416
5.024
8.226
7.286
 CA
NH1
NH1
NH1
O
 O3'
C4'
OP1
O4'
O
6yw8 1 P01138 100.0 4e-86 NMR
 2021-05-12 ARG A:100 A:100 73.0 0.324 E -108.1 166.0 73.0 0.324 0.0
ARG B:100 B:100 74.0 0.329 E -108.2 166.0 74.0 0.329 0.0
4efv 1 ? 97.37 4e-81 X-RAY
 2012-08-22 ARG A:100 A:100 35.0 0.156 E -141.2 149.6 35.0 0.156 0.0 PO4
HOH
 2.792
3.496
 NE
CA
 O1
O
ARG B:100 B:100 34.0 0.151 E -133.3 149.1 34.0 0.151 0.0 PO4
HOH
 3.072
3.492
 NE
CA
 O1
O
5jz7 1 P01138 100.0 4e-80 X-RAY
 2017-01-11 ARG A:94 A:100 63.0 0.28 E -132.7 154.7 63.0 0.28 0.0
ARG B:94 B:100 63.0 0.28 E -129.3 155.5 63.0 0.28 0.0
ARG E:94 E:100 61.0 0.271 E -129.3 156.1 NA NA NA
ARG F:94 F:100 64.0 0.284 E -130.6 156.1 NA NA NA
4eax 1 P01139 89.17 1e-77 X-RAY
 2012-09-12 ARG A:100 A:100 30.0 0.133 E -128.2 148.6 30.0 0.133 0.0 S12
HOH
 5.980
3.590
 N
CG
 O4
O
ARG B:100 B:100 31.0 0.138 E -129.0 140.1 31.0 0.138 0.0 S12
HOH
 5.336
3.509
 N
CA
 C14
O
ARG C:100 C:100 27.0 0.12 E -130.4 146.7 NA NA NA
ARG D:100 D:100 30.0 0.133 E -127.6 144.0 NA NA NA
4xpj 1 P01139 89.17 1e-77 X-RAY
 2015-07-15 ARG A:100 A:100 35.0 0.156 E -131.1 137.4 35.0 0.156 0.0 LPY
HOH
 6.501
5.772
 N
N
 O5
O
ARG B:100 B:100 30.0 0.133 E -127.8 146.2 30.0 0.133 0.0 LPY
HOH
 6.143
3.050
 N
NE
 C33
O
1sgf 2 P01139 89.83 8e-77 X-RAY
 1998-05-27 ARG B:100 B:100 52.0 0.231 E -126.8 150.4 52.0 0.231 0.0
ARG E:100 Y:100 59.0 0.262 E -117.1 149.4 51.0 0.227 0.035 D:P00757:0.036
5lsd 1 P01139 89.83 8e-77 NMR
 2017-07-05 ARG A:100 A:100 115.0 0.511 E -125.0 178.1 99.0 0.44 0.071 B:P01139:0.071
ARG B:100 B:100 116.0 0.516 E -125.2 178.2 100.0 0.444 0.072 A:P01139:0.071
6ffy 2 P01139 90.43 4e-75 X-RAY
 2018-08-01 ARG B:100 B:221 45.0 0.2 E -102.9 161.4 45.0 0.2 0.0
ARG C:100 C:221 50.0 0.222 E -92.2 156.6 50.0 0.222 0.0
1btg 1 P01139 91.74 4e-71 X-RAY
 1996-03-08 ARG A:92 A:100 43.0 0.191 E -131.6 168.7 43.0 0.191 0.0 HOH
 3.208
 CG
 O
ARG B:92 B:100 36.0 0.16 E -152.1 157.8 36.0 0.16 0.0 HOH
 6.865
 NH1
 O
ARG C:92 C:100 43.0 0.191 E -148.0 159.5 43.0 0.191 0.0 HOH
 8.946
 O
 O
1bet 1 P01139 92.52 2e-70 X-RAY
 1994-05-31 ARG A:91 A:100 36.0 0.16 E -133.9 161.8 36.0 0.16 0.0 HOH
 7.377
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p01138-f1 1 P01138 100.0 0.0 ARG A:221 A:221 36.0 0.16 E -126.3 164.3