Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr1 | 115828864 | . | C | A | CCDS882.1:NM_002506.2:c.553Gtt>Ttt_NP_002497.2:p.185V>F | Homo sapiens nerve growth factor (NGF), mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 6xuo | 1 | F6SVV7 | 94.62 | 8e-146 |
X-RAY |
2020-01-29 | VAL | A:168 | A:64 | 126.0 | 0.813 | T | -127.0 | -63.2 | 126.0 | 0.813 | 0.0 | ||||||
| 3ij2 | 1 | P01139 | 82.19 | 2e-135 |
X-RAY |
2010-01-12 | VAL | A:167 | A:64 | 46.0 | 0.297 | B | -134.3 | 165.7 | 25.0 | 0.161 | 0.136 |
D:P07174:0.135 |
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| VAL | C:167 | B:64 | 46.0 | 0.297 | B | -140.9 | 163.1 | 24.0 | 0.155 | 0.142 |
B:P07174:0.142 |
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| 1sg1 | 1 | P01138 | 100.0 | 1e-87 |
X-RAY |
2004-06-01 | VAL | A:64 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| VAL | B:64 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| 1www | 1 | P01138 | 100.0 | 1e-87 |
X-RAY |
1999-09-15 | VAL | A:64 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| VAL | B:64 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| 2ifg | 2 | P01138 | 100.0 | 1e-87 |
X-RAY |
2007-02-13 | VAL | C:64 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| VAL | D:64 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| 4edw | 1 | P01138 | 100.0 | 1e-87 |
X-RAY |
2014-04-02 | VAL | A:64 | V:64 | 31.0 | 0.2 | 360.0 | -106.1 | 31.0 | 0.2 | 0.0 |
HOH |
8.368 |
CG2 |
O |
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| 4edx | 1 | P01138 | 100.0 | 1e-87 |
X-RAY |
2014-04-02 | VAL | A:64 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| VAL | D:64 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| 4zbn | 2 | P01138 | 100.0 | 1e-87 |
X-RAY |
2015-06-10 | VAL | C:64 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| VAL | D:64 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| 6yw8 | 1 | P01138 | 100.0 | 4e-86 |
NMR |
2021-05-12 | VAL | A:64 | A:64 | 40.0 | 0.258 | T | -120.7 | -9.9 | 37.0 | 0.239 | 0.019 |
B:P01138:0.019 |
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| VAL | B:64 | B:64 | 40.0 | 0.258 | T | -121.3 | -9.5 | 37.0 | 0.239 | 0.019 |
A:P01138:0.019 |
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| 4efv | 1 | ? | 97.37 | 4e-81 |
X-RAY |
2012-08-22 | VAL | A:64 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| VAL | B:64 | B:64 | 71.0 | 0.458 | S | -91.7 | -140.5 | 71.0 | 0.458 | 0.0 |
HOH |
7.118 |
CG1 |
O |
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| 5jz7 | 1 | P01138 | 100.0 | 4e-80 |
X-RAY |
2017-01-11 | VAL | A:58 | A:64 | 48.0 | 0.31 | B | -122.5 | 146.7 | 39.0 | 0.252 | 0.058 |
D:None:0.058 |
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| VAL | B:58 | B:64 | 49.0 | 0.316 | S | -122.6 | 146.8 | 41.0 | 0.265 | 0.051 |
L:None:0.052 |
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| VAL | E:58 | E:64 | 50.0 | 0.323 | B | -120.5 | 120.0 | NA | NA | NA | |||||||||||||
| VAL | F:58 | F:64 | 48.0 | 0.31 | S | -122.4 | 146.9 | NA | NA | NA | |||||||||||||
| 4eax | 1 | P01139 | 89.17 | 1e-77 |
X-RAY |
2012-09-12 | VAL | A:64 | A:64 | 49.0 | 0.316 | B | -71.0 | 153.1 | 49.0 | 0.316 | 0.0 | ||||||
| VAL | B:64 | B:64 | 51.0 | 0.329 | B | -100.5 | 154.2 | 51.0 | 0.329 | 0.0 | |||||||||||||
| VAL | C:64 | C:64 | 40.0 | 0.258 | B | -80.0 | 178.4 | NA | NA | NA | |||||||||||||
| VAL | D:64 | D:64 | 45.0 | 0.29 | B | -120.9 | 161.9 | NA | NA | NA | |||||||||||||
| 4xpj | 1 | P01139 | 89.17 | 1e-77 |
X-RAY |
2015-07-15 | VAL | A:64 | A:64 | 51.0 | 0.329 | B | -76.7 | 162.0 | 51.0 | 0.329 | 0.0 |
HOH |
6.027 |
CG2 |
O |
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| VAL | B:64 | B:64 | 46.0 | 0.297 | B | -106.5 | 159.0 | 46.0 | 0.297 | 0.0 |
HOH |
6.804 |
CG2 |
O |
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| 1sgf | 2 | P01139 | 89.83 | 8e-77 |
X-RAY |
1998-05-27 | VAL | B:64 | B:64 | 71.0 | 0.458 | B | -127.3 | 132.1 | 71.0 | 0.458 | 0.0 |
NAG NAG |
8.990 8.876 |
O O |
O6 C8 |
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| VAL | E:64 | Y:64 | 52.0 | 0.335 | B | -147.1 | 146.4 | 52.0 | 0.335 | 0.0 |
NAG NAG |
9.068 9.458 |
O O |
O6 C8 |
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| 5lsd | 1 | P01139 | 89.83 | 8e-77 |
NMR |
2017-07-05 | VAL | A:64 | A:64 | 47.0 | 0.303 | B | -122.2 | 154.4 | 47.0 | 0.303 | 0.0 | ||||||
| VAL | B:64 | B:64 | 49.0 | 0.316 | B | -122.6 | 154.7 | 49.0 | 0.316 | 0.0 | |||||||||||||
| 6ffy | 2 | P01139 | 90.43 | 4e-75 |
X-RAY |
2018-08-01 | VAL | B:64 | B:185 | 58.0 | 0.374 | B | -125.2 | -167.4 | 58.0 | 0.374 | 0.0 | ||||||
| VAL | C:64 | C:185 | 64.0 | 0.413 | B | -128.1 | -168.1 | 64.0 | 0.413 | 0.0 | |||||||||||||
| 1btg | 1 | P01139 | 91.74 | 4e-71 |
X-RAY |
1996-03-08 | VAL | A:56 | A:64 | 56.0 | 0.361 | B | -151.3 | 153.7 | 56.0 | 0.361 | 0.0 |
HOH |
3.382 |
CA |
O |
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| VAL | B:56 | B:64 | 57.0 | 0.368 | S | -118.6 | 174.6 | 57.0 | 0.368 | 0.0 | |||||||||||||
| VAL | C:56 | C:64 | 50.0 | 0.323 | B | -129.6 | 173.3 | 50.0 | 0.323 | 0.0 |
HOH |
7.272 |
N |
O |
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| 1bet | 1 | P01139 | 92.52 | 2e-70 |
X-RAY |
1994-05-31 | VAL | A:55 | A:64 | 44.0 | 0.284 | B | -134.7 | 158.2 | 44.0 | 0.284 | 0.0 |
HOH |
4.483 |
CG1 |
O |
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AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p01138-f1 | 1 | P01138 | 100.0 | 0.0 | VAL | A:185 | A:185 | 53.0 | 0.342 | B | -134.7 | 161.3 | |