Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 115828909 . A C CCDS882.1:NM_002506.2:c.508Ttc>Gtc_NP_002497.2:p.170F>V Homo sapiens nerve growth factor (NGF), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6xuo 1 F6SVV7 94.62 8e-146 X-RAY
 2020-01-29 PHE A:153 A:49 109.0 0.519 E -130.7 152.7 62.0 0.295 0.224 A:F6SVV7:0.224
3ij2 1 P01139 82.19 2e-135 X-RAY
 2010-01-12 PHE A:152 A:49 117.0 0.557 42.5 -115.1 69.0 0.329 0.228 D:P07174:0.229
PHE C:152 B:49 117.0 0.557 41.9 -115.3 72.0 0.343 0.214 B:P07174:0.214
1sg1 1 P01138 100.0 1e-87 X-RAY
 2004-06-01 PHE A:49 A:49 118.0 0.562 E -129.6 161.7 87.0 0.414 0.148 B:P01138:0.148
 HOH
 3.538
 CE2
 O
PHE B:49 B:49 111.0 0.529 E -124.1 149.1 9.0 0.043 0.486 A:P01138:0.286
C:P07174:0.281
 HOH
 4.643
 CE2
 O
1www 1 P01138 100.0 1e-87 X-RAY
 1999-09-15 PHE A:49 V:49 153.0 0.729 E -105.5 115.1 87.0 0.414 0.315 B:P01138:0.314
 HOH
 3.306
 CB
 O
PHE B:49 W:49 104.0 0.495 E -120.0 141.9 50.0 0.238 0.257 A:P01138:0.257
 HOH
 5.239
 N
 O
2ifg 2 P01138 100.0 1e-87 X-RAY
 2007-02-13 PHE C:49 E:49 115.0 0.548 E -105.6 115.2 70.0 0.333 0.215 D:P01138:0.214
PHE D:49 F:49 102.0 0.486 E -119.9 141.9 51.0 0.243 0.243 C:P01138:0.243
4edw 1 P01138 100.0 1e-87 X-RAY
 2014-04-02 PHE A:49 V:49 126.0 0.6 E -125.8 141.7 122.0 0.581 0.019 C:None:0.019
 HOH
 7.954
 CE2
 O
4edx 1 P01138 100.0 1e-87 X-RAY
 2014-04-02 PHE A:49 W:49 144.0 0.686 E -105.1 138.0 53.0 0.252 0.434 C:None:0.143
D:P01138:0.338
 HOH
 6.392
 CE2
 O
PHE D:49 V:49 129.0 0.614 E -106.0 136.5 53.0 0.252 0.362 F:None:0.081
A:P01138:0.295
4zbn 2 P01138 100.0 1e-87 X-RAY
 2015-06-10 PHE C:49 A:49 110.0 0.524 E -139.3 137.4 66.0 0.314 0.21 D:P01138:0.21
 DUZ
DUZ
DUZ
HOH
 8.248
5.613
9.767
6.733
 CD1
CE1
CE1
CB
 O3'
OP1
C29
O
PHE D:49 B:49 123.0 0.586 E -126.5 143.4 69.0 0.329 0.257 C:P01138:0.257
 DUZ
DUZ
HOH
 9.275
6.780
9.091
 CD1
CD1
CE1
 O3'
OP1
O
6yw8 1 P01138 100.0 4e-86 NMR
 2021-05-12 PHE A:49 A:49 112.0 0.533 E -123.9 113.1 93.0 0.443 0.09 B:P01138:0.09
PHE B:49 B:49 113.0 0.538 E -124.2 113.3 96.0 0.457 0.081 A:P01138:0.081
4efv 1 ? 97.37 4e-81 X-RAY
 2012-08-22 PHE A:49 A:49 107.0 0.51 E -117.5 151.3 50.0 0.238 0.272 B:None:0.271
 PO4
HOH
 8.734
5.883
 CE2
CB
 O1
O
PHE B:49 B:49 102.0 0.486 E -119.8 156.0 63.0 0.3 0.186 A:None:0.186
 PO4
HOH
 8.367
3.452
 CE2
CZ
 O3
O
5jz7 1 P01138 100.0 4e-80 X-RAY
 2017-01-11 PHE A:43 A:49 119.0 0.567 E -134.1 139.1 62.0 0.295 0.272 B:P01138:0.271
PHE B:43 B:49 116.0 0.552 E -133.9 137.7 62.0 0.295 0.257 A:P01138:0.257
PHE E:43 E:49 118.0 0.562 E -122.2 140.4 NA NA NA
PHE F:43 F:49 126.0 0.6 E -134.5 140.2 NA NA NA
4eax 1 P01139 89.17 1e-77 X-RAY
 2012-09-12 PHE A:49 A:49 115.0 0.548 E -99.1 122.2 70.0 0.333 0.215 E:None:0.214
 S12
HOH
 3.895
5.944
 CD1
CE1
 C8
O
PHE B:49 B:49 71.0 0.338 E -105.2 126.9 71.0 0.338 0.0 S12
HOH
 3.525
8.669
 CA
O
 N
O
PHE C:49 C:49 111.0 0.529 E -97.1 120.7 NA NA NA
PHE D:49 D:49 68.0 0.324 E -103.2 133.1 NA NA NA
4xpj 1 P01139 89.17 1e-77 X-RAY
 2015-07-15 PHE A:49 A:49 111.0 0.529 E -96.9 116.3 111.0 0.529 0.0 LPY
HOH
 4.090
4.308
 CD2
CG
 C35
O
PHE B:49 B:49 116.0 0.552 E -112.1 114.1 116.0 0.552 0.0 LPY
HOH
 3.145
3.564
 CA
CB
 O2
O
1sgf 2 P01139 89.83 8e-77 X-RAY
 1998-05-27 PHE B:49 B:49 104.0 0.495 E -162.5 138.3 30.0 0.143 0.352 E:P01139:0.352
PHE E:49 Y:49 105.0 0.5 -132.3 134.4 35.0 0.167 0.333 B:P01139:0.333
5lsd 1 P01139 89.83 8e-77 NMR
 2017-07-05 PHE A:49 A:49 123.0 0.586 E -120.8 136.1 67.0 0.319 0.267 B:P01139:0.267
PHE B:49 B:49 124.0 0.59 E -121.5 135.9 66.0 0.314 0.276 A:P01139:0.276
6ffy 2 P01139 90.43 4e-75 X-RAY
 2018-08-01 PHE B:49 B:170 98.0 0.467 E -108.3 153.9 45.0 0.214 0.253 C:P01139:0.243
A:Q9EPR5:0.005
PHE C:49 C:170 105.0 0.5 E -115.1 169.0 58.0 0.276 0.224 B:P01139:0.224
1btg 1 P01139 91.74 4e-71 X-RAY
 1996-03-08 PHE A:41 A:49 98.0 0.467 E -133.8 159.6 98.0 0.467 0.0 HOH
 6.572
 CZ
 O
PHE B:41 B:49 113.0 0.538 E -138.7 162.5 108.0 0.514 0.024 C:P01139:0.024
 HOH
 7.927
 CB
 O
PHE C:41 C:49 131.0 0.624 E -113.4 178.3 108.0 0.514 0.11 B:P01139:0.11
 HOH
 9.975
 O
 O
1bet 1 P01139 92.52 2e-70 X-RAY
 1994-05-31 PHE A:40 A:49 115.0 0.548 E -138.5 139.7 62.0 0.295 0.253 A:P01139:0.252
 HOH
 3.412
 CB
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p01138-f1 1 P01138 100.0 0.0 PHE A:170 A:170 46.0 0.219 E -96.2 141.7