Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr10 115481525 . T A CCDS7580.1:NM_033338.5:c.462gaT>gaA_NP_203124.1:p.154D>E Homo sapiens caspase 7 (CASP7), transcript variant a, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5v6u 1 P55210 100.0 0.0 X-RAY
 2017-10-18 ASP A:121 A:121 75.0 0.5 H -62.2 -50.3 75.0 0.5 0.0 HOH
 6.484
 O
 O
ASP B:121 B:121 63.0 0.42 H -79.3 -42.5 63.0 0.42 0.0 HOH
 5.312
 O
 O
5v6z 1 P55210 100.0 0.0 X-RAY
 2018-03-21 ASP A:121 A:121 104.0 0.693 H -71.9 -48.3 104.0 0.693 0.0
ASP B:121 B:121 53.0 0.353 H -63.7 -52.1 53.0 0.353 0.0 HOH
 5.295
 O
 O
4fdl 1 P55210 100.0 0.0 X-RAY
 2012-08-01 ASP A:123 A:121 67.0 0.447 H -80.4 -43.6 67.0 0.447 0.0 HOH
 2.839
 OD2
 O
ASP B:123 B:121 67.0 0.447 H -60.4 -51.6 67.0 0.447 0.0 HOH
 2.485
 OD2
 O
1kmc 1 P55210 99.67 0.0 X-RAY
 2002-01-16 ASP A:121 A:213 52.0 0.347 H -60.0 -53.3 52.0 0.347 0.0 HOH
 6.396
 OD2
 O
ASP B:121 B:213 54.0 0.36 H -59.8 -53.3 54.0 0.36 0.0 HOH
 8.869
 N
 O
1f1j 1 P55210 99.67 0.0 X-RAY
 2001-05-23 ASP A:123 A:121 59.0 0.393 H -70.9 -49.0 59.0 0.393 0.0 HOH
 2.660
 OD2
 O
ASP B:123 B:421 55.0 0.367 H -63.5 -48.8 NA NA NA
3r5k 1 P55210 99.01 0.0 X-RAY
 2011-06-29 ASP A:121 A:121 95.0 0.633 H -73.4 -53.7 95.0 0.633 0.0 HOH
 2.878
 CB
 O
ASP B:121 B:421 55.0 0.367 H -73.5 -37.3 55.0 0.367 0.0 HOH
 8.206
 OD2
 O
1i4o 1 P55210 100.0 0.0 X-RAY
 2001-03-21 ASP A:98 A:121 62.0 0.413 H -69.8 -40.8 62.0 0.413 0.0 HOH
 2.961
 N
 O
ASP B:98 B:121 70.0 0.467 H -57.1 -40.7 NA NA NA
1gqf 1 P55210 99.61 0.0 X-RAY
 2002-01-04 ASP A:75 A:213 68.0 0.453 H -54.3 -63.7 68.0 0.453 0.0
ASP B:75 B:213 72.0 0.48 H -66.3 -63.2 72.0 0.48 0.0 HOH
 3.382
 OD1
 O
1shj 1 P55210 99.61 0.0 X-RAY
 2004-08-17 ASP A:72 A:121 65.0 0.433 H -68.4 -53.6 65.0 0.433 0.0
ASP B:72 B:121 67.0 0.447 H -66.5 -48.9 67.0 0.447 0.0
4hq0 1 P55210 97.34 0.0 X-RAY
 2013-09-11 ASP A:76 A:121 78.0 0.52 H -64.1 -50.1 78.0 0.52 0.0
ASP B:76 B:121 60.0 0.4 H -61.9 -47.3 60.0 0.4 0.0
4hqr 1 P55210 97.34 0.0 X-RAY
 2013-09-11 ASP A:76 A:121 62.0 0.413 H -68.7 -34.3 62.0 0.413 0.0
ASP B:76 B:121 64.0 0.427 H -69.0 -39.0 64.0 0.427 0.0
1k86 1 P55210 99.6 0.0 X-RAY
 2001-11-21 ASP A:71 A:121 56.0 0.373 H -65.1 -44.7 56.0 0.373 0.0 HOH
 7.708
 O
 O
ASP B:71 B:121 50.0 0.333 H -63.8 -49.1 50.0 0.333 0.0 HOH
 2.568
 OD2
 O
3h1p 1 P55210 99.21 0.0 X-RAY
 2009-06-30 ASP A:72 A:121 70.0 0.467 H -74.3 -47.1 70.0 0.467 0.0 HOH
 3.340
 N
 O
ASP B:72 B:121 64.0 0.427 H -65.6 -47.4 64.0 0.427 0.0 HOH
 3.547
 CB
 O
1k88 1 P55210 99.21 0.0 X-RAY
 2001-11-21 ASP A:71 A:121 62.0 0.413 H -60.5 -46.9 62.0 0.413 0.0 HOH
 8.269
 O
 O
ASP B:71 B:121 79.0 0.527 H -63.3 -35.6 79.0 0.527 0.0 HOH
 2.612
 OD1
 O
4fea 1 P55210 100.0 0.0 X-RAY
 2012-08-01 ASP A:65 A:121 75.0 0.5 H -61.6 -35.6 75.0 0.5 0.0
ASP B:65 B:121 118.0 0.787 H -58.9 -32.6 118.0 0.787 0.0
4jj8 1 P55210 100.0 0.0 X-RAY
 2013-06-12 ASP A:65 A:121 69.0 0.46 H -62.7 -43.4 69.0 0.46 0.0
ASP B:65 B:121 69.0 0.46 H -62.5 -43.8 NA NA NA
4jr1 1 P55210 99.6 0.0 X-RAY
 2013-05-08 ASP A:68 A:121 71.0 0.473 H -67.6 -50.3 71.0 0.473 0.0 HOH
 3.002
 OD2
 O
ASP B:68 B:121 56.0 0.373 H -69.5 -51.8 56.0 0.373 0.0 HOH
 2.729
 OD2
 O
4jr2 1 P55210 99.6 0.0 X-RAY
 2013-05-08 ASP A:68 A:121 62.0 0.413 H -62.6 -43.5 62.0 0.413 0.0 HOH
 2.397
 OD1
 O
ASP B:68 B:121 62.0 0.413 H -66.4 -45.0 62.0 0.413 0.0 HOH
 2.766
 OD2
 O
1shl 1 P55210 95.55 1e-177 X-RAY
 2004-08-17 ASP A:65 A:121 60.0 0.4 H -66.6 -46.7 60.0 0.4 0.0
ASP B:65 B:121 66.0 0.44 H -62.5 -47.7 66.0 0.44 0.0
4zvo 1 P55210 100.0 1e-146 X-RAY
 2016-04-20 ASP A:121 A:121 65.0 0.433 H -56.3 -46.5 65.0 0.433 0.0
ASP C:121 C:421 66.0 0.44 H -57.4 -46.8 66.0 0.44 0.0
4zvp 1 P55210 100.0 1e-146 X-RAY
 2016-04-20 ASP A:121 A:121 65.0 0.433 H -70.0 -43.5 65.0 0.433 0.0 HOH
 4.776
 OD2
 O
ASP C:121 C:421 62.0 0.413 H -69.2 -47.1 62.0 0.413 0.0 HOH
 6.451
 OD2
 O
4zvq 1 P55210 100.0 1e-146 X-RAY
 2016-04-20 ASP A:121 A:121 68.0 0.453 H -72.8 -43.1 68.0 0.453 0.0 HOH
 5.013
 O
 O
ASP C:121 C:421 63.0 0.42 H -73.1 -43.4 63.0 0.42 0.0 HOH
 4.945
 O
 O
4zvr 1 P55210 100.0 1e-146 X-RAY
 2016-04-20 ASP A:121 A:121 68.0 0.453 H -65.3 -40.2 68.0 0.453 0.0 HOH
 7.131
 O
 O
ASP C:121 C:421 66.0 0.44 H -66.3 -44.4 66.0 0.44 0.0 HOH
 7.001
 OD2
 O
4zvs 1 P55210 100.0 1e-146 X-RAY
 2016-04-20 ASP A:121 A:121 65.0 0.433 H -68.3 -43.9 65.0 0.433 0.0 HOH
 3.523
 N
 O
ASP C:121 C:421 63.0 0.42 H -69.2 -43.2 63.0 0.42 0.0 HOH
 3.287
 CA
 O
4zvt 1 P55210 100.0 1e-146 X-RAY
 2016-04-20 ASP A:121 A:121 72.0 0.48 H -61.4 -44.4 72.0 0.48 0.0
ASP C:121 C:421 70.0 0.467 H -62.1 -44.1 70.0 0.467 0.0
4zvu 1 P55210 100.0 1e-146 X-RAY
 2016-04-20 ASP A:121 A:121 71.0 0.473 H -67.3 -45.9 71.0 0.473 0.0
ASP C:121 C:421 68.0 0.453 H -67.0 -46.0 68.0 0.453 0.0
5ic6 1 P55210 100.0 1e-146 X-RAY
 2016-07-20 ASP A:121 A:121 71.0 0.473 H -66.2 -37.5 71.0 0.473 0.0
ASP C:121 C:121 66.0 0.44 H -65.5 -36.9 NA NA NA
5k20 1 P55210 100.0 1e-146 X-RAY
 2017-01-11 ASP A:121 A:121 65.0 0.433 H -65.4 -43.9 65.0 0.433 0.0 HOH
 8.260
 O
 O
ASP C:121 C:421 63.0 0.42 H -66.9 -44.6 63.0 0.42 0.0 HOH
 3.661
 N
 O
6cl1 1 P55210 100.0 1e-146 X-RAY
 2019-03-06 ASP A:121 A:121 83.0 0.553 H -69.9 -46.9 83.0 0.553 0.0
ASP C:121 C:121 65.0 0.433 H -75.5 -39.9 65.0 0.433 0.0
6cl2 1 P55210 100.0 1e-146 X-RAY
 2019-03-06 ASP A:121 A:121 75.0 0.5 H -75.1 -41.3 75.0 0.5 0.0 HOH
 8.883
 O
 O
ASP C:121 C:121 52.0 0.347 H -65.3 -47.5 52.0 0.347 0.0 HOH
 7.367
 O
 O
6x8j 1 P55210 100.0 1e-146 X-RAY
 2021-06-02 ASP A:121 A:121 60.0 0.4 H -73.5 -41.0 60.0 0.4 0.0 HOH
 8.756
 N
 O
ASP C:121 B:121 78.0 0.52 H -74.4 -41.7 78.0 0.52 0.0 HOH
 9.072
 O
 O
6x8l 1 P55210 100.0 1e-146 X-RAY
 2021-06-02 ASP A:121 A:121 71.0 0.473 H -70.7 -45.8 71.0 0.473 0.0 HOH
 7.691
 O
 O
ASP C:121 B:121 100.0 0.667 H -76.7 -44.3 100.0 0.667 0.0 HOH
 9.005
 O
 O
4jb8 1 P55210 100.0 1e-128 X-RAY
 2013-08-21 ASP A:98 A:121 80.0 0.533 H -72.0 -36.1 80.0 0.533 0.0 HOH
 2.300
 OD2
 O
4lsz 1 P55210 100.0 1e-128 X-RAY
 2014-07-02 ASP A:98 A:121 91.0 0.607 H -64.6 -41.1 49.0 0.327 0.28 E:None:0.28
 HOH
 7.355
 O
 O
ASP C:98 C:121 97.0 0.647 H -64.9 -40.3 39.0 0.26 0.387 F:None:0.387
 HOH
 5.289
 OD2
 O
2ql5 1 P55210 100.0 4e-127 X-RAY
 2007-08-28 ASP A:98 A:121 61.0 0.407 H -64.0 -44.5 61.0 0.407 0.0 HOH
 3.460
 N
 O
ASP C:98 C:421 62.0 0.413 H -60.6 -47.9 62.0 0.413 0.0 HOH
 3.363
 N
 O
2ql7 1 P55210 100.0 4e-127 X-RAY
 2007-08-28 ASP A:98 A:121 65.0 0.433 H -63.8 -43.8 65.0 0.433 0.0 HOH
 5.739
 OD2
 O
ASP C:98 C:421 68.0 0.453 H -60.6 -48.0 68.0 0.453 0.0 HOH
 2.578
 OD2
 O
2ql9 1 P55210 100.0 4e-127 X-RAY
 2007-08-28 ASP A:98 A:121 63.0 0.42 H -62.8 -42.6 63.0 0.42 0.0 HOH
 3.380
 CA
 O
ASP C:98 C:421 65.0 0.433 H -63.4 -42.4 65.0 0.433 0.0 HOH
 2.681
 OD2
 O
2qlb 1 P55210 100.0 4e-127 X-RAY
 2007-08-28 ASP A:98 A:121 60.0 0.4 H -67.4 -36.3 60.0 0.4 0.0 HOH
 3.357
 N
 O
ASP C:98 C:421 62.0 0.413 H -65.9 -40.6 62.0 0.413 0.0 HOH
 2.556
 OD2
 O
2qlf 1 P55210 100.0 4e-127 X-RAY
 2007-08-28 ASP A:98 A:121 65.0 0.433 H -57.9 -47.1 65.0 0.433 0.0 HOH
 8.537
 N
 O
ASP C:98 C:421 58.0 0.387 H -67.1 -50.8 58.0 0.387 0.0 HOH
 4.630
 OD1
 O
2qlj 1 P55210 100.0 4e-127 X-RAY
 2007-08-28 ASP A:98 A:121 58.0 0.387 H -65.4 -42.1 58.0 0.387 0.0
ASP C:98 C:421 65.0 0.433 H -62.4 -47.3 65.0 0.433 0.0 HOH
 4.439
 OD1
 O
3edr 1 P55210 100.0 4e-127 X-RAY
 2008-10-28 ASP A:98 A:121 70.0 0.467 H -65.4 -40.0 70.0 0.467 0.0 HOH
 4.349
 OD1
 O
ASP C:98 C:421 66.0 0.44 H -64.4 -48.0 66.0 0.44 0.0 HOH
 3.345
 CA
 O
3ibc 1 P55210 100.0 4e-127 X-RAY
 2009-09-01 ASP A:98 A:121 62.0 0.413 H -55.9 -54.1 62.0 0.413 0.0 HOH
 8.658
 O
 O
ASP C:98 C:421 70.0 0.467 H -61.5 -48.8 70.0 0.467 0.0 HOH
 7.832
 O
 O
3ibf 1 P55210 100.0 4e-127 X-RAY
 2009-09-01 ASP A:98 A:121 65.0 0.433 H -68.7 -46.8 65.0 0.433 0.0
ASP C:98 C:421 59.0 0.393 H -64.8 -46.2 59.0 0.393 0.0 HOH
 7.196
 OD2
 O
1i51 1 P55210 99.32 6e-107 X-RAY
 2002-02-23 ASP A:71 A:121 61.0 0.407 H -58.3 -53.7 61.0 0.407 0.0
ASP C:71 C:121 69.0 0.46 H -57.2 -48.0 69.0 0.46 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p55210-f1 1 P55210 100.0 0.0 ASP A:121 A:121 55.0 0.367 H -59.9 -44.7