Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr10 115485285 . T A CCDS7580.1:NM_033338.5:c.640Ttc>Atc_NP_203124.1:p.214F>I Homo sapiens caspase 7 (CASP7), transcript variant a, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5v6u 1 P55210 100.0 0.0 X-RAY
 2017-10-18 PHE A:181 A:181 2.0 0.01 E -115.9 124.4 2.0 0.01 0.0 HOH
 9.239
 CE1
 O
PHE B:181 B:181 2.0 0.01 E -126.0 118.9 2.0 0.01 0.0 8YM
HOH
 6.895
7.118
 CE1
O
 C12
O
5v6z 1 P55210 100.0 0.0 X-RAY
 2018-03-21 PHE A:181 A:181 0.0 0.0 E -122.8 124.6 0.0 0.0 0.0 HOH
 8.980
 CE1
 O
PHE B:181 B:181 2.0 0.01 E -135.8 121.6 2.0 0.01 0.0 8YJ
HOH
 5.940
8.724
 CE1
CE1
 OAQ
O
4fdl 1 P55210 100.0 0.0 X-RAY
 2012-08-01 PHE A:183 A:181 1.0 0.005 E -124.3 128.9 1.0 0.005 0.0 HOH
 7.086
 CE1
 O
PHE B:183 B:181 1.0 0.005 E -131.5 119.9 1.0 0.005 0.0 HOH
 7.366
 CE1
 O
1kmc 1 P55210 99.67 0.0 X-RAY
 2002-01-16 PHE A:181 A:280 1.0 0.005 E -132.5 117.8 1.0 0.005 0.0 HOH
 7.698
 CE1
 O
PHE B:181 B:280 0.0 0.0 E -129.5 118.9 0.0 0.0 0.0 HOH
 6.760
 O
 O
1f1j 1 P55210 99.67 0.0 X-RAY
 2001-05-23 PHE A:183 A:181 0.0 0.0 E -123.6 127.3 0.0 0.0 0.0 HOH
 6.789
 CE1
 O
PHE B:183 B:481 0.0 0.0 E -140.0 125.6 NA NA NA
3r5k 1 P55210 99.01 0.0 X-RAY
 2011-06-29 PHE A:181 A:181 1.0 0.005 E -120.3 122.6 1.0 0.005 0.0 HOH
 7.516
 O
 O
PHE B:181 B:481 1.0 0.005 E -127.6 133.1 1.0 0.005 0.0 HOH
 6.861
 CB
 O
1i4o 1 P55210 100.0 0.0 X-RAY
 2001-03-21 PHE A:158 A:181 1.0 0.005 E -125.9 120.7 1.0 0.005 0.0 HOH
 6.549
 CE1
 O
PHE B:158 B:181 1.0 0.005 E -130.4 110.3 NA NA NA
1gqf 1 P55210 99.61 0.0 X-RAY
 2002-01-04 PHE A:135 A:280 0.0 0.0 E -120.6 113.4 0.0 0.0 0.0
PHE B:135 B:280 0.0 0.0 E -128.1 106.2 0.0 0.0 0.0
1shj 1 P55210 99.61 0.0 X-RAY
 2004-08-17 PHE A:132 A:181 1.0 0.005 E -119.6 114.2 1.0 0.005 0.0 NXN
 6.985
 O
 CL4
PHE B:132 B:181 1.0 0.005 E -113.1 115.4 1.0 0.005 0.0 NXN
 7.138
 CB
 C11
4hq0 1 P55210 97.34 0.0 X-RAY
 2013-09-11 PHE A:136 A:181 1.0 0.005 E -125.1 120.6 1.0 0.005 0.0
PHE B:136 B:181 2.0 0.01 E -125.2 114.9 2.0 0.01 0.0
4hqr 1 P55210 97.34 0.0 X-RAY
 2013-09-11 PHE A:136 A:181 1.0 0.005 E -125.9 118.2 1.0 0.005 0.0
PHE B:136 B:181 2.0 0.01 E -125.7 108.3 2.0 0.01 0.0
1k86 1 P55210 99.6 0.0 X-RAY
 2001-11-21 PHE A:131 A:181 0.0 0.0 E -127.7 117.8 0.0 0.0 0.0
PHE B:131 B:181 1.0 0.005 E -125.6 108.9 1.0 0.005 0.0 HOH
 8.836
 O
 O
3h1p 1 P55210 99.21 0.0 X-RAY
 2009-06-30 PHE A:132 A:181 0.0 0.0 E -118.2 129.0 0.0 0.0 0.0 HOH
 6.830
 O
 O
PHE B:132 B:181 1.0 0.005 E -130.6 125.0 1.0 0.005 0.0 HOH
 6.859
 O
 O
1k88 1 P55210 99.21 0.0 X-RAY
 2001-11-21 PHE A:131 A:181 1.0 0.005 E -125.2 114.5 1.0 0.005 0.0 HOH
 9.551
 O
 O
PHE B:131 B:181 0.0 0.0 E -121.4 117.0 0.0 0.0 0.0 HOH
 8.785
 O
 O
4fea 1 P55210 100.0 0.0 X-RAY
 2012-08-01 PHE A:125 A:181 17.0 0.081 E -113.2 116.9 17.0 0.081 0.0 0TE
0TE
 9.869
7.772
 O
CD2
 C2
C10
PHE B:125 B:181 6.0 0.029 E -155.3 117.8 6.0 0.029 0.0 0TE
 7.811
 CB
 C10
4jj8 1 P55210 100.0 0.0 X-RAY
 2013-06-12 PHE A:125 A:181 0.0 0.0 E -128.7 116.5 0.0 0.0 0.0 HOH
 6.900
 CE2
 O
PHE B:125 B:181 2.0 0.01 E -129.0 116.7 NA NA NA
4jr1 1 P55210 99.6 0.0 X-RAY
 2013-05-08 PHE A:128 A:181 1.0 0.005 E -127.8 113.6 1.0 0.005 0.0 HOH
 6.437
 CE1
 O
PHE B:128 B:181 1.0 0.005 E -122.6 110.6 1.0 0.005 0.0 HOH
 7.051
 O
 O
4jr2 1 P55210 99.6 0.0 X-RAY
 2013-05-08 PHE A:128 A:181 1.0 0.005 E -125.0 124.0 1.0 0.005 0.0 HOH
 6.801
 O
 O
PHE B:128 B:181 1.0 0.005 E -122.0 125.8 1.0 0.005 0.0 HOH
 6.612
 CE1
 O
1shl 1 P55210 95.55 1e-177 X-RAY
 2004-08-17 PHE A:125 A:181 1.0 0.005 E -120.7 117.1 1.0 0.005 0.0 FXN
 5.646
 CB
 F18
PHE B:125 B:181 1.0 0.005 E -127.2 113.1 1.0 0.005 0.0 FXN
FXN
 5.828
9.866
 CB
O
 F18
S19
4zvo 1 P55210 100.0 1e-146 X-RAY
 2016-04-20 PHE A:181 A:181 58.0 0.276 E -121.8 121.9 3.0 0.014 0.262 B:P55210:0.262
 HOH
 8.306
 CB
 O
PHE C:181 C:481 57.0 0.271 E -124.1 122.3 0.0 0.0 0.271 D:P55210:0.271
 HOH
 8.446
 CB
 O
4zvp 1 P55210 100.0 1e-146 X-RAY
 2016-04-20 PHE A:181 A:181 55.0 0.262 E -128.8 122.4 2.0 0.01 0.252 B:P55210:0.252
 HOH
 7.538
 CE1
 O
PHE C:181 C:481 54.0 0.257 E -130.0 122.7 1.0 0.005 0.252 D:P55210:0.252
 HOH
 7.034
 O
 O
4zvq 1 P55210 100.0 1e-146 X-RAY
 2016-04-20 PHE A:181 A:181 53.0 0.252 E -130.2 119.3 2.0 0.01 0.242 B:P55210:0.243
 HOH
 8.525
 O
 O
PHE C:181 C:481 57.0 0.271 E -130.2 119.1 1.0 0.005 0.266 D:P55210:0.267
 HOH
 8.073
 CB
 O
4zvr 1 P55210 100.0 1e-146 X-RAY
 2016-04-20 PHE A:181 A:181 58.0 0.276 E -123.9 123.7 2.0 0.01 0.266 B:P55210:0.267
 HOH
 6.808
 O
 O
PHE C:181 C:481 56.0 0.267 E -126.3 123.9 1.0 0.005 0.262 D:P55210:0.262
 HOH
 6.848
 O
 O
4zvs 1 P55210 100.0 1e-146 X-RAY
 2016-04-20 PHE A:181 A:181 56.0 0.267 E -128.3 113.6 1.0 0.005 0.262 B:P55210:0.262
 HOH
 8.453
 O
 O
PHE C:181 C:481 56.0 0.267 E -128.7 113.9 0.0 0.0 0.267 D:P55210:0.267
 HOH
 8.019
 CB
 O
4zvt 1 P55210 100.0 1e-146 X-RAY
 2016-04-20 PHE A:181 A:181 57.0 0.271 E -126.1 115.3 2.0 0.01 0.261 B:P55210:0.262
PHE C:181 C:481 57.0 0.271 E -126.2 115.7 0.0 0.0 0.271 D:P55210:0.271
4zvu 1 P55210 100.0 1e-146 X-RAY
 2016-04-20 PHE A:181 A:181 54.0 0.257 E -123.9 122.1 2.0 0.01 0.247 B:P55210:0.248
PHE C:181 C:481 57.0 0.271 E -124.0 122.0 1.0 0.005 0.266 D:P55210:0.267
 HOH
 8.490
 O
 O
5ic6 1 P55210 100.0 1e-146 X-RAY
 2016-07-20 PHE A:181 A:181 54.0 0.257 E -129.0 115.8 0.0 0.0 0.257 B:P55210:0.257
PHE C:181 C:181 57.0 0.271 E -126.0 117.1 NA NA NA
5k20 1 P55210 100.0 1e-146 X-RAY
 2017-01-11 PHE A:181 A:181 55.0 0.262 E -127.1 120.2 1.0 0.005 0.257 B:P55210:0.257
 HOH
 9.105
 CE1
 O
PHE C:181 C:481 55.0 0.262 E -125.1 120.1 1.0 0.005 0.257 D:P55210:0.257
 HOH
 6.656
 CE1
 O
6cl1 1 P55210 100.0 1e-146 X-RAY
 2019-03-06 PHE A:181 A:181 56.0 0.267 E -125.6 117.5 0.0 0.0 0.267 B:P55210:0.267
 HOH
 8.299
 CE1
 O
PHE C:181 C:181 56.0 0.267 E -128.0 115.5 1.0 0.005 0.262 D:P55210:0.262
 HOH
 8.687
 CE1
 O
6cl2 1 P55210 100.0 1e-146 X-RAY
 2019-03-06 PHE A:181 A:181 55.0 0.262 E -125.0 119.2 0.0 0.0 0.262 B:P55210:0.262
 HOH
 6.923
 O
 O
PHE C:181 C:181 55.0 0.262 E -126.8 117.3 1.0 0.005 0.257 D:P55210:0.257
 HOH
 6.929
 O
 O
6x8j 1 P55210 100.0 1e-146 X-RAY
 2021-06-02 PHE A:181 A:181 54.0 0.257 E -130.3 117.7 0.0 0.0 0.257 B:P55210:0.257
 HOH
 7.204
 CE1
 O
PHE C:181 B:181 53.0 0.252 E -130.2 119.3 0.0 0.0 0.252 D:P55210:0.252
 HOH
 9.989
 CB
 O
6x8l 1 P55210 100.0 1e-146 X-RAY
 2021-06-02 PHE A:181 A:181 55.0 0.262 E -129.6 120.9 1.0 0.005 0.257 B:P55210:0.257
 HOH
 8.667
 O
 O
PHE C:181 B:181 53.0 0.252 E -123.0 123.0 1.0 0.005 0.247 D:P55210:0.248
 HOH
 6.909
 O
 O
4jb8 1 P55210 100.0 1e-128 X-RAY
 2013-08-21 PHE A:158 A:181 56.0 0.267 E -122.0 122.6 1.0 0.005 0.262 B:P55210:0.262
 HOH
 6.828
 O
 O
4lsz 1 P55210 100.0 1e-128 X-RAY
 2014-07-02 PHE A:158 A:181 56.0 0.267 E -125.1 118.0 1.0 0.005 0.262 B:P55210:0.262
 HOH
 6.975
 CE1
 O
PHE C:158 C:181 59.0 0.281 E -124.6 119.5 1.0 0.005 0.276 D:P55210:0.276
 HOH
 7.017
 O
 O
2ql5 1 P55210 100.0 4e-127 X-RAY
 2007-08-28 PHE A:158 A:181 52.0 0.248 E -133.0 122.7 2.0 0.01 0.238 B:P55210:0.238
 HOH
 6.919
 O
 O
PHE C:158 C:481 56.0 0.267 E -131.6 117.1 1.0 0.005 0.262 D:P55210:0.262
 CIT
HOH
 8.797
6.847
 O
O
 O1
O
2ql7 1 P55210 100.0 4e-127 X-RAY
 2007-08-28 PHE A:158 A:181 56.0 0.267 E -126.1 121.6 3.0 0.014 0.253 B:P55210:0.252
 HOH
 7.003
 O
 O
PHE C:158 C:481 57.0 0.271 E -130.3 117.7 1.0 0.005 0.266 D:P55210:0.267
 CIT
HOH
 8.920
6.977
 CB
O
 O2
O
2ql9 1 P55210 100.0 4e-127 X-RAY
 2007-08-28 PHE A:158 A:181 55.0 0.262 E -130.3 121.6 2.0 0.01 0.252 B:P55210:0.252
 HOH
 6.633
 CE1
 O
PHE C:158 C:481 55.0 0.262 E -128.6 119.8 1.0 0.005 0.257 D:P55210:0.257
 CIT
HOH
 8.684
6.900
 CB
O
 O1
O
2qlb 1 P55210 100.0 4e-127 X-RAY
 2007-08-28 PHE A:158 A:181 56.0 0.267 E -127.1 120.0 1.0 0.005 0.262 B:P55210:0.262
 HOH
 6.722
 CE1
 O
PHE C:158 C:481 60.0 0.286 E -133.2 118.3 1.0 0.005 0.281 D:P55210:0.281
 CIT
HOH
 9.005
6.893
 O
O
 O1
O
2qlf 1 P55210 100.0 4e-127 X-RAY
 2007-08-28 PHE A:158 A:181 56.0 0.267 E -125.0 118.3 0.0 0.0 0.267 B:P55210:0.267
 HOH
 6.696
 O
 O
PHE C:158 C:481 51.0 0.243 E -134.4 111.8 1.0 0.005 0.238 D:P55210:0.238
 HOH
 9.542
 O
 O
2qlj 1 P55210 100.0 4e-127 X-RAY
 2007-08-28 PHE A:158 A:181 53.0 0.252 E -127.4 120.6 2.0 0.01 0.242 B:P55210:0.243
 HOH
 6.515
 CE1
 O
PHE C:158 C:481 55.0 0.262 E -129.5 116.9 1.0 0.005 0.257 D:P55210:0.257
 CIT
 8.976
 O
 O1
3edr 1 P55210 100.0 4e-127 X-RAY
 2008-10-28 PHE A:158 A:181 53.0 0.252 E -128.6 120.3 2.0 0.01 0.242 B:P55210:0.243
PHE C:158 C:481 57.0 0.271 E -132.5 116.7 1.0 0.005 0.266 D:P55210:0.267
 HOH
 6.757
 CE1
 O
3ibc 1 P55210 100.0 4e-127 X-RAY
 2009-09-01 PHE A:158 A:181 59.0 0.281 E -124.1 124.1 3.0 0.014 0.267 B:P55210:0.267
 HOH
 7.054
 CE1
 O
PHE C:158 C:481 58.0 0.276 E -130.8 120.4 2.0 0.01 0.266 D:P55210:0.267
 HOH
 7.010
 CE1
 O
3ibf 1 P55210 100.0 4e-127 X-RAY
 2009-09-01 PHE A:158 A:181 54.0 0.257 E -126.6 121.6 1.0 0.005 0.252 B:P55210:0.252
 HOH
 7.770
 CB
 O
PHE C:158 C:481 56.0 0.267 E -126.9 115.9 0.0 0.0 0.267 D:P55210:0.267
 HOH
 7.036
 CE1
 O
1i51 1 P55210 99.32 6e-107 X-RAY
 2002-02-23 PHE A:131 A:181 55.0 0.262 E -120.0 109.4 0.0 0.0 0.262 B:P55210:0.262
PHE C:131 C:181 55.0 0.262 E -122.6 113.6 1.0 0.005 0.257 D:P55210:0.257

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p55210-f1 1 P55210 100.0 0.0 PHE A:181 A:181 1.0 0.005 E -119.7 117.0