Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr14 54416940 . G A CCDS9715.1:NM_001202.3:c.1037gCt>gTt_NP_001193.2:p.346A>V Homo sapiens bone morphogenetic protein 4 (BMP4), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6omn 1 P12643 88.89 3e-69 X-RAY
 2019-05-08 ALA A:46 E:52 60.0 0.522 -80.7 173.8 60.0 0.522 0.0 NAG
 9.899
 O
 C8
ALA B:46 F:52 28.0 0.243 -67.2 167.6 28.0 0.243 0.0 NAG
HOH
 9.271
3.433
 CB
CA
 C8
O
ALA C:46 G:52 56.0 0.487 -70.4 158.1 NA NA NA
ALA D:46 H:52 50.0 0.435 -70.0 160.9 NA NA NA
2h64 1 P12643 85.71 1e-68 X-RAY
 2007-04-10 ALA A:52 A:52 45.0 0.391 -72.7 164.6 4.0 0.035 0.356 B:P36894:0.357
 HOH
 2.790
 O
 O
1es7 1 P12643 87.5 2e-68 X-RAY
 2000-10-07 ALA A:54 A:52 43.0 0.374 -73.1 155.3 3.0 0.026 0.348 B:P36894:0.348
 HOH
 2.730
 N
 O
ALA C:54 C:552 42.0 0.365 -73.3 155.1 2.0 0.017 0.348 D:P36894:0.348
 HOH
 2.671
 N
 O
2qj9 1 P12643 87.5 2e-68 X-RAY
 2008-01-15 ALA A:54 B:52 46.0 0.4 -65.7 160.0 4.0 0.035 0.365 C:P36894:0.365
 HOH
 2.820
 O
 O
ALA B:54 A:52 46.0 0.4 -67.5 161.1 4.0 0.035 0.365 D:P36894:0.365
 HOH
 2.885
 N
 O
2qja 1 P12643 87.5 2e-68 X-RAY
 2008-01-15 ALA A:54 A:52 49.0 0.426 -66.9 163.8 4.0 0.035 0.391 C:P36894:0.391
 HOH
 2.812
 N
 O
ALA B:54 B:52 47.0 0.409 -73.3 173.9 6.0 0.052 0.357 D:P36894:0.357
 HOH
 2.860
 O
 O
2qjb 1 P12643 87.5 2e-68 X-RAY
 2008-01-15 ALA A:54 A:52 43.0 0.374 -61.3 163.4 2.0 0.017 0.357 C:P36894:0.357
 HOH
 3.082
 O
 O
ALA B:54 B:52 45.0 0.391 -63.7 169.8 5.0 0.043 0.348 D:P36894:0.348
 HOH
 2.794
 N
 O
1rew 1 P12643 87.5 4e-68 X-RAY
 2004-05-04 ALA A:52 A:52 46.0 0.4 -76.8 161.7 4.0 0.035 0.365 C:P36894:0.365
 HOH
 2.875
 N
 O
ALA B:52 B:52 47.0 0.409 -77.8 165.2 4.0 0.035 0.374 D:P36894:0.374
 HOH
 2.863
 N
 O
2goo 1 P12643 87.5 4e-68 X-RAY
 2006-05-09 ALA A:52 A:52 47.0 0.409 -73.0 164.0 5.0 0.043 0.366 B:P36894:0.365
 HOH
 2.784
 O
 O
ALA D:52 D:52 46.0 0.4 -77.1 156.4 3.0 0.026 0.374 E:P36894:0.374
 HOH
 2.845
 N
 O
2h62 1 P12643 87.5 4e-68 X-RAY
 2007-04-10 ALA A:52 A:52 35.0 0.304 -55.4 126.8 35.0 0.304 0.0 HOH
 2.687
 O
 O
ALA B:52 B:52 49.0 0.426 -73.0 165.5 3.0 0.026 0.4 C:P36894:0.4
 HOH
 2.894
 O
 O
3bmp 1 P12643 87.5 4e-68 X-RAY
 2000-03-12 ALA A:52 A:52 30.0 0.261 -47.9 133.3 30.0 0.261 0.0 HOH
 7.651
 O
 O
4uhy 1 P12643 87.5 4e-68 X-RAY
 2015-05-06 ALA A:52 A:334 83.0 0.722 T -49.0 -23.8 83.0 0.722 0.0
ALA B:52 B:334 66.0 0.574 T -57.8 133.1 27.0 0.235 0.339 C:Q96B86:0.339
4uhz 1 P12643 87.5 4e-68 X-RAY
 2015-05-06 ALA A:52 A:334 31.0 0.27 T -72.7 133.4 31.0 0.27 0.0 SO4
 8.654
 CB
 O2
4ui0 1 P12643 87.5 4e-68 X-RAY
 2015-05-06 ALA A:52 NA:NA DO NA DO DO DO NA NA NA
ALA B:52 B:334 1.0 0.009 H -31.4 -47.5 1.0 0.009 0.0 HOH
 9.590
 CB
 O
4ui1 1 P12643 87.5 4e-68 X-RAY
 2015-05-06 ALA A:52 A:334 66.0 0.574 T -72.7 23.9 10.0 0.087 0.487 D:Q6ZVN8:0.487
 NO3
CL
HOH
 8.081
3.702
3.263
 CB
N
CB
 O2
CL
O
ALA B:52 B:334 66.0 0.574 T -54.1 98.2 NA NA NA
4ui2 2 P12643 87.5 4e-68 X-RAY
 2015-05-06 ALA B:52 B:334 0.0 0.0 H -63.0 -23.9 0.0 0.0 0.0
3bk3 1 P12643 85.71 5e-68 X-RAY
 2008-05-27 ALA A:52 A:52 26.0 0.226 -101.8 118.1 26.0 0.226 0.0 HOH
 4.244
 CB
 O
ALA B:52 B:52 30.0 0.261 -106.4 121.1 30.0 0.261 0.0 HOH
 3.490
 N
 O
1reu 1 P12643 90.2 5e-68 X-RAY
 2004-05-04 ALA A:41 A:52 39.0 0.339 -57.7 152.3 39.0 0.339 0.0 MPD
HOH
 9.496
4.832
 O
O
 O4
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p12644-f1 1 P12644 100.0 0.0 ALA A:346 A:346 40.0 0.348 -75.5 140.3