Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr15 67473647 . C A CCDS10222.1:NM_005902.3:c.727Cgc>Agc_NP_005893.1:p.243R>S Homo sapiens SMAD family member 3 (SMAD3), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1khx 1 Q15796 92.51 1e-157 X-RAY
 2002-02-06 ARG A:45 A:285 80.0 0.356 E -73.5 135.3 69.0 0.307 0.049 A:Q15796:0.049
 HOH
 2.577
 NH1
 O
6zvq 1 Q15796 92.51 1e-157 X-RAY
 2021-06-09 ARG A:45 A:285 91.0 0.404 E -73.2 137.8 78.0 0.347 0.057 A:Q15796:0.058
 GOL
GOL
TAR
GOL
GOL
HOH
 7.612
6.099
9.362
9.609
3.740
3.040
 NH2
O
NH2
NH1
NH1
N
 O3
O3
O1
O3
O3
O
1mk2 1 P84022 100.0 4e-154 X-RAY
 2002-10-16 ARG A:24 A:242 81.0 0.36 E -78.9 141.8 81.0 0.36 0.0
6m64 1 Q15796 96.1 6e-149 X-RAY
 2020-11-25 ARG A:26 A:285 91.0 0.404 E -62.2 136.0 91.0 0.404 0.0 HOH
 2.878
 NE
 O
ARG C:26 C:285 86.0 0.382 E -66.8 140.0 85.0 0.378 0.004 E:Q15796:0.004
 HOH
 2.697
 O
 O
ARG E:26 E:285 89.0 0.396 E -62.9 139.7 83.0 0.369 0.027 C:Q15796:0.027
 HOH
 2.832
 NH1
 O
7co1 1 Q15796 96.1 6e-149 X-RAY
 2020-11-25 ARG A:26 A:285 90.0 0.4 E -70.7 134.1 84.0 0.373 0.027 E:Q15796:0.027
ARG C:26 C:285 91.0 0.404 E -70.7 134.7 80.0 0.356 0.048 A:Q15796:0.049
ARG E:26 E:285 90.0 0.4 E -71.2 135.7 75.0 0.333 0.067 C:Q15796:0.067
1u7f 1 P84022 100.0 2e-147 X-RAY
 2004-09-28 ARG A:16 A:243 87.0 0.387 E -65.1 126.4 78.0 0.347 0.04 B:Q13485:0.04
 HOH
 2.208
 NH2
 O
ARG C:16 C:243 85.0 0.378 E -90.1 124.7 71.0 0.316 0.062 A:P84022:0.062
 HOH
 3.232
 N
 O
5xoc 1 P84022 100.0 2e-147 X-RAY
 2018-03-28 ARG A:26 A:243 87.0 0.387 E -63.4 136.3 85.0 0.378 0.009 A:P84022:0.009
 HOH
 2.721
 NH2
 O
1mjs 1 P84022 100.0 9e-147 X-RAY
 2002-10-16 ARG A:15 A:242 84.0 0.373 E -77.7 133.8 84.0 0.373 0.0 HOH
 2.896
 N
 O
1u7v 1 Q15796 96.97 6e-145 X-RAY
 2004-09-28 ARG A:16 A:285 89.0 0.396 E -74.7 130.5 81.0 0.36 0.036 C:Q13485:0.036
ARG B:16 C:285 95.0 0.422 E -75.8 118.3 84.0 0.373 0.049 A:Q15796:0.049
5xod 1 Q15796 97.46 3e-144 X-RAY
 2018-03-28 ARG A:26 A:285 84.0 0.373 E -64.8 137.4 80.0 0.356 0.017 A:Q15796:0.018
 HOH
 2.456
 NH1
 O
5zoj 1 Q15796 97.46 4e-144 X-RAY
 2018-10-10 ARG A:27 A:285 83.0 0.369 E -74.6 146.2 83.0 0.369 0.0
ARG B:27 B:285 80.0 0.356 E -76.2 146.6 80.0 0.356 0.0
ARG C:27 C:285 92.0 0.409 E -74.2 144.9 91.0 0.404 0.005 B:Q15796:0.004
1dev 1 Q15796 97.45 9e-144 X-RAY
 2000-01-21 ARG A:25 A:285 72.0 0.32 E -78.4 122.7 72.0 0.32 0.0
ARG C:25 C:285 69.0 0.307 E -73.5 127.8 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p84022-f1 1 P84022 100.0 0.0 ARG A:243 A:243 121.0 0.538 E -71.0 135.3
af-q15796-f1 1 Q15796 83.73 0.0 ARG A:285 A:285 132.0 0.587 E -70.9 134.8