Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr15 67473756 . G A CCDS10222.1:NM_005902.3:c.836aGg>aAg_NP_005893.1:p.279R>K Homo sapiens SMAD family member 3 (SMAD3), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1khx 1 Q15796 92.51 1e-157 X-RAY
 2002-02-06 ARG A:81 A:321 51.0 0.227 -58.2 141.0 51.0 0.227 0.0 HOH
 2.887
 NH1
 O
6zvq 1 Q15796 92.51 1e-157 X-RAY
 2021-06-09 ARG A:81 A:321 48.0 0.213 -74.4 150.9 48.0 0.213 0.0 GOL
GOL
TAR
HOH
 2.299
6.703
3.238
3.400
 NH1
NH2
NH1
CA
 H31
O1
O1
O
1mk2 1 P84022 100.0 4e-154 X-RAY
 2002-10-16 ARG A:60 A:278 61.0 0.271 -51.1 137.3 61.0 0.271 0.0
6m64 1 Q15796 96.1 6e-149 X-RAY
 2020-11-25 ARG A:62 A:321 47.0 0.209 -66.0 137.6 47.0 0.209 0.0 HOH
 3.071
 NH1
 O
ARG C:62 C:321 50.0 0.222 -80.2 146.1 50.0 0.222 0.0 HOH
 2.413
 O
 O
ARG E:62 E:321 43.0 0.191 -55.4 146.6 43.0 0.191 0.0 HOH
 2.787
 O
 O
7co1 1 Q15796 96.1 6e-149 X-RAY
 2020-11-25 ARG A:62 A:321 53.0 0.236 -72.4 131.1 53.0 0.236 0.0
ARG C:62 C:321 44.0 0.196 -72.9 130.5 44.0 0.196 0.0
ARG E:62 E:321 53.0 0.236 -74.3 128.7 53.0 0.236 0.0
1u7f 1 P84022 100.0 2e-147 X-RAY
 2004-09-28 ARG A:52 A:279 44.0 0.196 -70.8 128.1 44.0 0.196 0.0 HOH
 2.911
 CA
 O
ARG C:52 C:279 49.0 0.218 -84.2 127.2 32.0 0.142 0.076 B:Q13485:0.076
 HOH
 3.338
 CD
 O
5xoc 1 P84022 100.0 2e-147 X-RAY
 2018-03-28 ARG A:62 A:279 57.0 0.253 -66.3 134.7 57.0 0.253 0.0 HOH
 7.367
 NH2
 O
1mjs 1 P84022 100.0 9e-147 X-RAY
 2002-10-16 ARG A:51 A:278 46.0 0.204 -73.1 128.9 46.0 0.204 0.0 HOH
 2.635
 NH2
 O
1u7v 1 Q15796 96.97 6e-145 X-RAY
 2004-09-28 ARG A:52 A:321 43.0 0.191 -66.8 128.2 43.0 0.191 0.0
ARG B:52 C:321 52.0 0.231 -81.6 128.7 29.0 0.129 0.102 C:Q13485:0.102
5xod 1 Q15796 97.46 3e-144 X-RAY
 2018-03-28 ARG A:62 A:321 54.0 0.24 -96.3 131.3 54.0 0.24 0.0 HOH
 3.333
 CA
 O
5zoj 1 Q15796 97.46 4e-144 X-RAY
 2018-10-10 ARG A:63 A:321 59.0 0.262 -67.6 132.0 59.0 0.262 0.0
ARG B:63 B:321 45.0 0.2 -68.2 133.5 45.0 0.2 0.0
ARG C:63 C:321 47.0 0.209 -66.4 132.4 47.0 0.209 0.0
1dev 1 Q15796 97.45 9e-144 X-RAY
 2000-01-21 ARG A:61 A:321 51.0 0.227 -67.7 118.5 51.0 0.227 0.0
ARG C:61 C:321 59.0 0.262 -76.5 118.8 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p84022-f1 1 P84022 100.0 0.0 ARG A:279 A:279 55.0 0.244 -68.2 122.7
af-q15796-f1 1 Q15796 83.73 0.0 ARG A:321 A:321 64.0 0.284 -67.4 121.3