Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr15 67479795 . C A CCDS10222.1:NM_005902.3:c.1102Cga>Aga_NP_005893.1:p.368R>R Homo sapiens SMAD family member 3 (SMAD3), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1khx 1 Q15796 92.51 1e-157 X-RAY
 2002-02-06 ARG A:170 A:410 141.0 0.627 G -61.3 -30.4 141.0 0.627 0.0 HOH
 3.050
 O
 O
6zvq 1 Q15796 92.51 1e-157 X-RAY
 2021-06-09 ARG A:170 A:410 144.0 0.64 G -64.9 -27.5 144.0 0.64 0.0 SO4
TAR
GOL
HOH
 9.154
2.632
4.808
3.138
 NH1
CG
CD
O
 O2
O3
H2
O
1mk2 1 P84022 100.0 4e-154 X-RAY
 2002-10-16 ARG A:149 A:367 124.0 0.551 G -57.7 -28.2 124.0 0.551 0.0 ACY
ACY
ACY
 3.641
9.317
8.208
 CZ
NH2
NH1
 CH3
O
CH3
6m64 1 Q15796 96.1 6e-149 X-RAY
 2020-11-25 ARG A:151 A:410 177.0 0.787 G -65.9 -28.2 141.0 0.627 0.16 E:Q15796:0.16
 HOH
 2.919
 O
 O
ARG C:151 C:410 148.0 0.658 G -65.6 -26.1 141.0 0.627 0.031 A:Q15796:0.031
 HOH
 2.861
 O
 O
ARG E:151 E:410 164.0 0.729 G -59.1 -27.8 130.0 0.578 0.151 C:Q15796:0.151
 HOH
 3.068
 O
 O
7co1 1 Q15796 96.1 6e-149 X-RAY
 2020-11-25 ARG A:151 A:410 143.0 0.636 G -65.0 -23.5 120.0 0.533 0.103 E:Q15796:0.102
ARG C:151 C:410 145.0 0.644 G -65.6 -24.0 123.0 0.547 0.097 A:Q15796:0.098
ARG E:151 E:410 151.0 0.671 G -64.9 -23.3 131.0 0.582 0.089 C:Q15796:0.089
1u7f 1 P84022 100.0 2e-147 X-RAY
 2004-09-28 ARG A:141 A:368 140.0 0.622 G -67.3 -20.0 140.0 0.622 0.0 HOH
 3.248
 CG
 O
ARG C:141 C:368 201.0 0.893 G -63.0 -31.9 188.0 0.836 0.057 A:P84022:0.058
 HOH
 2.642
 NH1
 O
5xoc 1 P84022 100.0 2e-147 X-RAY
 2018-03-28 ARG A:151 A:368 167.0 0.742 G -69.2 -16.9 83.0 0.369 0.373 B:P0AA25+O75593:0.373
 HOH
 6.770
 NH2
 O
1mjs 1 P84022 100.0 9e-147 X-RAY
 2002-10-16 ARG A:140 A:367 182.0 0.809 G -62.6 -27.1 182.0 0.809 0.0 HOH
 3.833
 CA
 O
1u7v 1 Q15796 96.97 6e-145 X-RAY
 2004-09-28 ARG A:141 A:410 137.0 0.609 G -65.5 -26.6 125.0 0.556 0.053 C:Q13485:0.053
ARG B:141 C:410 196.0 0.871 G -59.4 -30.7 186.0 0.827 0.044 A:Q15796:0.044
5xod 1 Q15796 97.46 3e-144 X-RAY
 2018-03-28 ARG A:151 A:410 106.0 0.471 G -61.5 -27.5 106.0 0.471 0.0 HOH
 3.284
 NH1
 O
5zoj 1 Q15796 97.46 4e-144 X-RAY
 2018-10-10 ARG A:152 A:410 147.0 0.653 G -69.8 -17.3 147.0 0.653 0.0
ARG B:152 B:410 158.0 0.702 G -69.1 -21.9 149.0 0.662 0.04 A:Q15796:0.04
ARG C:152 C:410 159.0 0.707 G -68.5 -20.4 150.0 0.667 0.04 B:Q15796:0.04
1dev 1 Q15796 97.45 9e-144 X-RAY
 2000-01-21 ARG A:150 A:410 106.0 0.471 G -66.9 -35.4 106.0 0.471 0.0
ARG C:150 C:410 101.0 0.449 G -62.9 -28.7 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p84022-f1 1 P84022 100.0 0.0 ARG A:368 A:368 111.0 0.493 G -64.5 -30.1
af-q15796-f1 1 Q15796 83.73 0.0 ARG A:410 A:410 92.0 0.409 G -64.5 -30.9