Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr16 75258061 . G A CCDS32490.1:NM_001906.4:c.605gGg>gAg_NP_001897.4:p.202G>E Homo sapiens chymotrypsinogen B1 (CTRB1), mRNA.
pdb_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id
alphafold_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1acb 1 P00766 81.63 3e-148 X-RAY
1993-10-31 GLY A:184 E:184 7.0 0.093 E 113.7 -144.7 7.0 0.093 0.0 HOH
3.504
CA
O
1cgi 1 P00766 81.63 3e-148 X-RAY
1993-10-31 GLY A:184 E:184 4.0 0.053 E 119.7 -153.4 4.0 0.053 0.0 HOH
3.134
O
O
1cgj 1 P00766 81.63 3e-148 X-RAY
1993-10-31 GLY A:184 E:184 3.0 0.04 E 101.6 -134.1 3.0 0.04 0.0 HOH
3.115
O
O
1chg 1 P00766 81.63 3e-148 X-RAY
1976-11-22 GLY A:184 A:184 0.0 0.0 E 133.0 -119.1 0.0 0.0 0.0
1ex3 1 P00766 81.63 3e-148 X-RAY
2000-05-17 GLY A:184 A:184 2.0 0.027 E 136.7 -150.5 2.0 0.027 0.0 HOH
6.896
O
O
1gcd 1 P00766 81.63 3e-148 X-RAY
1994-06-22 GLY A:184 A:184 5.0 0.067 E 108.4 -137.4 5.0 0.067 0.0 HOH
3.551
CA
O
1gl0 1 P00766 81.63 3e-148 X-RAY
2001-11-28 GLY A:184 E:184 5.0 0.067 E 116.9 -143.2 5.0 0.067 0.0 HOH
3.250
CA
O
1gl1 1 P00766 81.63 3e-148 X-RAY
2001-11-28 GLY A:184 A:184 5.0 0.067 E 106.8 -148.9 5.0 0.067 0.0 HOH
2.846
O
O
GLY B:184 B:184 6.0 0.08 E 110.8 -144.2 NA NA NA
GLY C:184 C:184 7.0 0.093 E 111.2 -142.8 NA NA NA
1k2i 1 P00766 81.63 3e-148 X-RAY
2001-12-05 GLY A:184 1:184 3.0 0.04 E 115.5 -141.0 3.0 0.04 0.0 SN1
HOH
9.827
3.344
CA
CA
CE1
O
1oxg 1 P00766 81.63 3e-148 X-RAY
2004-05-18 GLY A:184 A:184 6.0 0.08 E 107.7 -140.5 6.0 0.08 0.0 HOH
2.682
O
O
1p2m 1 P00766 81.63 3e-148 X-RAY
2004-04-20 GLY A:184 A:184 5.0 0.067 E 104.9 -140.1 5.0 0.067 0.0 HOH
2.810
O
O
GLY C:184 C:184 4.0 0.053 E 104.6 -140.0 NA NA NA
1p2n 1 P00766 81.63 3e-148 X-RAY
2004-04-20 GLY A:184 A:184 5.0 0.067 E 106.7 -139.3 5.0 0.067 0.0 HOH
2.788
O
O
GLY C:184 C:184 4.0 0.053 E 104.7 -138.9 NA NA NA
1p2o 1 P00766 81.63 3e-148 X-RAY
2004-04-20 GLY A:184 A:184 5.0 0.067 E 108.6 -139.0 5.0 0.067 0.0 HOH
3.002
O
O
GLY C:184 C:184 4.0 0.053 E 105.6 -139.6 NA NA NA
1p2q 1 P00766 81.63 3e-148 X-RAY
2004-04-20 GLY A:184 A:184 4.0 0.053 E 106.5 -140.9 4.0 0.053 0.0 HOH
2.846
O
O
GLY C:184 C:184 4.0 0.053 E 107.8 -139.3 NA NA NA
1t7c 1 P00766 81.63 3e-148 X-RAY
2005-03-08 GLY A:184 A:184 5.0 0.067 E 108.3 -142.4 5.0 0.067 0.0 HOH
2.930
O
O
GLY C:184 C:184 4.0 0.053 E 106.0 -140.3 NA NA NA
1t8l 1 P00766 81.63 3e-148 X-RAY
2005-03-08 GLY A:184 A:184 5.0 0.067 E 108.5 -138.1 5.0 0.067 0.0 HOH
2.816
O
O
GLY C:184 C:184 4.0 0.053 E 108.0 -137.6 NA NA NA
1t8m 1 P00766 81.63 3e-148 X-RAY
2005-03-08 GLY A:184 A:184 5.0 0.067 E 106.8 -141.3 5.0 0.067 0.0 HOH
2.876
O
O
GLY C:184 C:184 4.0 0.053 E 105.9 -140.4 NA NA NA
1t8n 1 P00766 81.63 3e-148 X-RAY
2005-03-08 GLY A:184 A:184 5.0 0.067 E 107.3 -141.5 5.0 0.067 0.0 HOH
2.997
O
O
GLY C:184 C:184 4.0 0.053 E 104.7 -139.5 NA NA NA
1t8o 1 P00766 81.63 3e-148 X-RAY
2005-03-08 GLY A:184 A:184 4.0 0.053 E 107.2 -141.0 4.0 0.053 0.0 HOH
2.864
O
O
GLY C:184 C:184 4.0 0.053 E 106.6 -140.5 NA NA NA
2cga 1 P00766 81.63 3e-148 X-RAY
1987-04-16 GLY A:184 A:184 2.0 0.027 E 100.5 -141.0 2.0 0.027 0.0 HOH
3.181
O
O
GLY B:184 B:184 4.0 0.053 E 118.4 -140.4 4.0 0.053 0.0 HOH
2.886
O
O
2y6t 1 P00766 81.63 3e-148 X-RAY
2011-04-20 GLY A:184 A:184 4.0 0.053 E 98.2 -124.1 4.0 0.053 0.0 HOH
8.339
O
O
GLY B:184 B:184 4.0 0.053 E 111.7 -141.6 4.0 0.053 0.0
GLY C:184 C:184 4.0 0.053 E 117.3 -135.3 NA NA NA
GLY D:184 D:184 5.0 0.067 E 100.6 -128.7 NA NA NA
3t62 1 P00766 81.63 3e-148 X-RAY
2012-08-01 GLY A:184 A:184 5.0 0.067 E 107.9 -137.3 5.0 0.067 0.0 HOH
2.777
O
O
GLY C:184 B:184 5.0 0.067 E 108.2 -133.1 NA NA NA
GLY E:184 C:184 4.0 0.053 E 106.1 -130.3 NA NA NA
4q2k 1 P00766 81.63 3e-148 X-RAY
2014-07-23 GLY A:184 A:184 4.0 0.053 E 100.1 -136.9 4.0 0.053 0.0 5BF
5BF
HOH
9.796
6.480
5.874
CA
O
CA
C44
C21
O
GLY B:184 B:184 4.0 0.053 E 108.8 -133.1 NA NA NA
GLY C:184 C:184 5.0 0.067 E 111.9 -138.4 NA NA NA
GLY D:184 D:184 5.0 0.067 E 108.4 -134.1 5.0 0.067 0.0 5BF
HOH
9.824
3.517
CA
CA
C42
O
5j4q 1 P00766 81.63 3e-148 X-RAY
2017-04-12 GLY A:184 A:184 5.0 0.067 E 104.7 -130.7 5.0 0.067 0.0 HOH
3.923
CA
O
5j4s 1 P00766 81.63 3e-148 X-RAY
2017-04-12 GLY A:184 A:184 3.0 0.04 E 107.2 -136.5 3.0 0.04 0.0 HOH
2.566
HA3
O
7kty 1 P00766 81.63 3e-148 X-RAY
2021-03-10 GLY A:184 A:184 2.0 0.027 E 116.8 -141.5 2.0 0.027 0.0 HOH
3.626
CA
O
7ktz 1 P00766 81.63 3e-148 X-RAY
2021-03-10 GLY A:184 A:184 3.0 0.04 E 119.4 -142.8 3.0 0.04 0.0 HOH
2.912
O
O
7ku0 1 P00766 81.63 3e-148 X-RAY
2021-03-10 GLY A:184 A:184 2.0 0.027 E 119.1 -144.2 2.0 0.027 0.0 HOH
2.727
O
O
7ku1 1 P00766 81.63 3e-148 X-RAY
2021-03-10 GLY A:184 A:184 3.0 0.04 E 115.7 -145.0 3.0 0.04 0.0
7ku2 1 P00766 81.63 3e-148 X-RAY
2021-03-10 GLY A:184 A:184 3.0 0.04 E 113.0 -141.4 3.0 0.04 0.0 HOH
6.825
CA
O
7ku3 1 P00766 81.63 3e-148 X-RAY
2021-03-10 GLY A:184 A:184 3.0 0.04 E 121.7 -139.8 3.0 0.04 0.0 HOH
2.906
O
O
1dlk 2 P00766 80.87 2e-137 X-RAY
2000-05-03 GLY B:169 B:184 4.0 0.053 E 101.5 -147.1 4.0 0.053 0.0 HOH
3.413
CA
O
GLY D:169 D:184 5.0 0.067 E 113.8 -141.7 NA NA NA
1ab9 3 P00766 80.21 5e-51 X-RAY
1997-08-20 GLY C:36 C:184 5.0 0.067 E 115.1 -141.9 5.0 0.067 0.0 HOH
2.794
O
O
1ca0 3 P00766 80.21 5e-51 X-RAY
1997-07-23 GLY C:36 C:184 3.0 0.04 E 100.0 -138.9 3.0 0.04 0.0 HOH
3.378
CA
O
GLY G:36 H:184 2.0 0.027 E 125.2 -146.7 NA NA NA
1cbw 3 P00766 80.21 5e-51 X-RAY
1997-07-23 GLY C:36 C:184 6.0 0.08 E 132.0 -150.6 6.0 0.08 0.0 HOH
3.649
CA
O
GLY G:36 H:184 6.0 0.08 E 102.8 -130.3 NA NA NA
1cho 3 P00766 80.21 5e-51 X-RAY
1988-07-16 GLY C:36 G:184 4.0 0.053 E 109.4 -146.5 4.0 0.053 0.0 HOH
2.996
O
O
1gct 3 P00766 80.21 5e-51 X-RAY
1991-10-15 GLY C:36 C:184 3.0 0.04 E 107.3 -143.1 3.0 0.04 0.0 HOH
2.793
O
O
1gg6 3 P00766 80.21 5e-51 X-RAY
2000-09-20 GLY C:36 C:184 4.0 0.053 E 110.5 -141.3 4.0 0.053 0.0 SO4
APF
HOH
9.385
9.454
3.365
N
CA
CA
O3
CP3
O
1ggd 3 P00766 80.21 5e-51 X-RAY
2000-09-20 GLY C:36 C:184 4.0 0.053 E 113.5 -143.4 4.0 0.053 0.0 FAF
HOH
9.479
3.298
CA
CA
CE2
O
1gha 3 P00766 80.21 5e-51 X-RAY
1994-06-22 GLY C:36 G:184 4.0 0.053 E 115.0 -146.0 4.0 0.053 0.0 HOH
3.220
CA
O
1ghb 3 P00766 80.21 5e-51 X-RAY
1994-06-22 GLY C:36 G:184 4.0 0.053 E 129.2 -150.9 4.0 0.053 0.0 ACE
TRP
HEX
HOH
6.516
6.822
9.088
2.953
CA
N
C
CA
O
OXT
C1
O
1gmc 3 P00766 80.21 5e-51 X-RAY
1993-10-31 GLY C:36 G:184 4.0 0.053 E 117.4 -140.3 4.0 0.053 0.0 HOH
3.164
CA
O
1gmd 3 P00766 80.21 5e-51 X-RAY
1993-10-31 GLY C:36 G:184 4.0 0.053 E 112.7 -138.0 4.0 0.053 0.0 HEX
HOH
9.352
3.347
CA
CA
C2
O
1gmh 3 P00766 80.21 5e-51 X-RAY
1994-09-30 GLY C:36 G:184 5.0 0.067 E 108.3 -137.9 5.0 0.067 0.0 HOH
2.567
O
O
1hja 3 P00766 80.21 5e-51 X-RAY
1998-01-14 GLY C:36 C:184 5.0 0.067 E 105.2 -149.2 5.0 0.067 0.0 HOH
3.120
CA
O
1mtn 3 P00766 80.21 5e-51 X-RAY
1996-08-17 GLY C:36 C:184 8.0 0.107 E 106.4 -143.4 8.0 0.107 0.0 HOH
4.927
CA
O
GLY G:36 G:184 6.0 0.08 E 114.5 -142.4 NA NA NA
1n8o 3 P00766 80.21 5e-51 X-RAY
2002-12-18 GLY C:36 C:184 6.0 0.08 E 113.4 -137.9 6.0 0.08 0.0 HOH
3.466
CA
O
1vgc 3 P00766 80.21 5e-51 X-RAY
1997-11-12 GLY C:36 C:184 4.0 0.053 E 106.7 -143.1 4.0 0.053 0.0 V36
HOH
8.668
2.648
CA
O
CL4
O
1yph 3 P00766 80.21 5e-51 X-RAY
2006-02-14 GLY C:36 E:184 5.0 0.067 E 111.6 -143.5 5.0 0.067 0.0 HOH
2.692
O
O
GLY F:36 F:184 4.0 0.053 E 104.8 -140.8 4.0 0.053 0.0 HOH
3.470
CA
O
2cha 3 P00766 80.21 5e-51 X-RAY
1977-01-18 GLY C:36 C:184 2.0 0.027 E 97.2 -129.0 2.0 0.027 0.0 HOH
4.544
CA
O
GLY F:36 G:184 4.0 0.053 E 97.2 -129.0 4.0 0.053 0.0
2gch 3 P00766 80.21 5e-51 X-RAY
1980-07-09 GLY C:36 G:184 3.0 0.04 E 119.7 -149.1 3.0 0.04 0.0 HOH
3.101
O
O
2gct 3 P00766 80.21 5e-51 X-RAY
1991-10-15 GLY C:36 C:184 3.0 0.04 E 110.3 -145.9 3.0 0.04 0.0 HOH
3.042
O
O
2gmt 3 P00766 80.21 5e-51 X-RAY
1994-11-01 GLY C:36 C:184 3.0 0.04 E 111.2 -140.5 3.0 0.04 0.0 HOH
2.830
O
O
2p8o 3 P00766 80.21 5e-51 X-RAY
2007-05-08 GLY C:36 C:184 4.0 0.053 E 110.4 -139.3 4.0 0.053 0.0 BVA
HOH
8.260
3.312
CA
CA
C19
O
2vgc 3 P00766 80.21 5e-51 X-RAY
1997-11-12 GLY C:36 C:184 3.0 0.04 E 110.7 -141.8 3.0 0.04 0.0 V35
HOH
8.857
2.813
CA
O
CL4
O
3bg4 3 P00766 80.21 5e-51 X-RAY
2008-07-29 GLY C:36 C:184 3.0 0.04 E 113.4 -139.0 3.0 0.04 0.0 HOH
3.662
O
O
3gch 3 P00766 80.21 5e-51 X-RAY
1990-10-15 GLY C:36 C:184 5.0 0.067 E 98.8 -126.3 5.0 0.067 0.0 HOH
3.351
CA
O
3gct 3 P00766 80.21 5e-51 X-RAY
1991-10-15 GLY C:36 G:184 4.0 0.053 E 106.0 -144.0 4.0 0.053 0.0 HOH
2.806
O
O
3vgc 3 P00766 80.21 5e-51 X-RAY
1997-11-12 GLY C:36 C:184 3.0 0.04 E 108.1 -141.6 3.0 0.04 0.0 SRB
HOH
8.254
2.738
CA
O
C9
O
4cha 3 P00766 80.21 5e-51 X-RAY
1985-04-01 GLY C:36 C:184 5.0 0.067 E 109.5 -141.0 5.0 0.067 0.0 HOH
3.381
CA
O
GLY F:36 G:184 7.0 0.093 E 99.4 -133.8 7.0 0.093 0.0 HOH
3.632
CA
O
4gch 3 P00766 80.21 5e-51 X-RAY
1990-10-15 GLY C:36 G:184 2.0 0.027 E 107.7 -137.0 2.0 0.027 0.0 DMC
HOH
8.309
3.405
CA
CA
CM2
O
4vgc 3 P00766 80.21 5e-51 X-RAY
1997-11-12 GLY C:36 C:184 3.0 0.04 E 104.8 -142.1 3.0 0.04 0.0 SRD
HOH
9.662
2.827
CA
O
C9
O
5cha 3 P00766 80.21 5e-51 X-RAY
1985-04-01 GLY C:36 C:184 7.0 0.093 E 102.2 -133.0 7.0 0.093 0.0 HOH
3.477
CA
O
GLY F:36 G:184 5.0 0.067 E 105.9 -137.4 5.0 0.067 0.0 HOH
2.322
N
O
5gch 3 P00766 80.21 5e-51 X-RAY
1990-10-15 GLY C:36 G:184 4.0 0.053 E 108.3 -144.9 4.0 0.053 0.0 HOH
3.262
CA
O
5r42 3 P00766 80.21 5e-51 X-RAY
2021-09-01 GLY C:36 C:184 4.0 0.053 E 108.0 -136.1 4.0 0.053 0.0 HOH
3.451
CA
O
5r43 3 P00766 80.21 5e-51 X-RAY
2021-09-01 GLY C:36 C:184 3.0 0.04 E 106.4 -135.7 3.0 0.04 0.0 HOH
3.393
CA
O
5r44 3 P00766 80.21 5e-51 X-RAY
2021-09-01 GLY C:36 C:184 4.0 0.053 E 107.9 -136.4 4.0 0.053 0.0 HOH
3.456
CA
O
5r45 3 P00766 80.21 5e-51 X-RAY
2021-09-01 GLY C:36 C:184 5.0 0.067 E 106.0 -136.1 5.0 0.067 0.0 HOH
2.749
O
O
5r46 3 P00766 80.21 5e-51 X-RAY
2021-09-01 GLY C:36 C:184 4.0 0.053 E 108.3 -136.4 4.0 0.053 0.0 HOH
3.442
CA
O
5r47 3 P00766 80.21 5e-51 X-RAY
2021-09-01 GLY C:36 C:184 4.0 0.053 E 105.3 -136.1 4.0 0.053 0.0 HOH
3.389
CA
O
5r48 3 P00766 80.21 5e-51 X-RAY
2021-09-01 GLY C:36 C:184 4.0 0.053 E 108.3 -136.5 4.0 0.053 0.0 HOH
3.445
CA
O
5r49 3 P00766 80.21 5e-51 X-RAY
2021-09-01 GLY C:36 C:184 4.0 0.053 E 106.2 -135.4 4.0 0.053 0.0 HOH
3.408
CA
O
5r4a 3 P00766 80.21 5e-51 X-RAY
2021-09-01 GLY C:36 C:184 4.0 0.053 E 109.4 -136.3 4.0 0.053 0.0 HOH
3.443
CA
O
5r4b 3 P00766 80.21 5e-51 X-RAY
2021-09-01 GLY C:36 C:184 4.0 0.053 E 105.6 -135.4 4.0 0.053 0.0 HOH
3.390
CA
O
5r4c 3 P00766 80.21 5e-51 X-RAY
2021-09-01 GLY C:36 C:184 4.0 0.053 E 107.9 -137.3 4.0 0.053 0.0 HOH
3.452
CA
O
5r4d 3 P00766 80.21 5e-51 X-RAY
2021-09-01 GLY C:36 C:184 4.0 0.053 E 107.4 -134.6 4.0 0.053 0.0 HOH
3.379
CA
O
6cha 3 P00766 80.21 5e-51 X-RAY
1987-04-16 GLY C:36 C:184 6.0 0.08 E 106.0 -150.8 6.0 0.08 0.0 PBA
HOH
8.988
3.014
CA
CA
CE2
O
GLY F:36 G:184 5.0 0.067 E 103.4 -139.1 5.0 0.067 0.0 PBA
HOH
9.570
2.649
CA
O
CE2
O
6di8 3 P00766 80.21 5e-51 X-RAY
2019-01-23 GLY C:36 C:184 5.0 0.067 E 104.7 -132.4 5.0 0.067 0.0 HOH
2.761
O
O
GLY F:36 F:184 5.0 0.067 E 106.2 -131.5 NA NA NA
GLY I:36 I:184 5.0 0.067 E 104.6 -132.5 NA NA NA
GLY L:36 L:184 5.0 0.067 E 106.7 -131.8 NA NA NA
6gch 3 P00766 80.21 5e-51 X-RAY
1990-10-15 GLY C:36 G:184 2.0 0.027 E 106.2 -141.1 2.0 0.027 0.0 APF
HOH
9.939
3.209
CA
CA
CP3
O
7gch 3 P00766 80.21 5e-51 X-RAY
1990-10-15 GLY C:36 G:184 3.0 0.04 E 115.4 -136.7 2.0 0.027 0.013 B:P00766:0.013
LPF
HOH
9.648
2.259
CA
O
CP5
O
7jrx 3 P00766 80.21 5e-51 X-RAY
2021-07-21 GLY C:36 C:184 6.0 0.08 E 108.9 -132.3 6.0 0.08 0.0 HOH
2.629
O
O
GLY G:36 c:184 5.0 0.067 E 107.2 -129.4 NA NA NA
8gch 3 P00766 80.21 5e-51 X-RAY
1992-04-15 GLY C:36 G:184 4.0 0.053 E 105.3 -142.5 4.0 0.053 0.0 HOH
3.298
CA
O
1afq 3 P00766 80.21 6e-51 X-RAY
1997-09-17 GLY C:35 C:184 4.0 0.053 E 113.6 -141.7 4.0 0.053 0.0 0FG
HOH
8.713
2.830
CA
O
F
O
3ru4 5 P00766 80.21 6e-51 X-RAY
2012-08-29 GLY E:35 E:184 3.0 0.04 E 110.9 -134.4 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p17538-f1 1 P17538 100.0 0.0 GLY A:202 A:202 4.0 0.053 E 87.0 -133.7
af-q6gpi1-f1 1 Q6GPI1 95.82 0.0 GLY A:202 A:202 4.0 0.053 E 93.7 -134.6