Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 6707931 . C A CCDS32883.1:NM_000064.2:c.1855Gtg>Ttg_NP_000055.2:p.619V>L Homo sapiens complement component 3 (C3), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2wii 1 P01024 100.0 0.0 X-RAY
 2009-06-09 VAL A:597 A:597 48.0 0.31 H -57.0 -44.8 48.0 0.31 0.0 HOH
 3.456
 CG2
 O
2win 1 P01024 100.0 0.0 X-RAY
 2009-06-09 VAL A:597 A:597 58.0 0.374 H -76.8 -43.3 58.0 0.374 0.0
VAL C:597 C:597 55.0 0.355 H -76.8 -43.3 NA NA NA
VAL E:597 E:597 59.0 0.381 H -76.8 -43.3 NA NA NA
VAL G:597 G:597 68.0 0.439 H -76.8 -43.3 68.0 0.439 0.0
2xwj 1 P01024 100.0 0.0 X-RAY
 2011-01-12 VAL A:597 A:597 59.0 0.381 H -72.4 -38.3 59.0 0.381 0.0
VAL C:597 C:597 59.0 0.381 H -72.8 -38.2 NA NA NA
VAL E:597 E:597 59.0 0.381 H -73.0 -38.1 NA NA NA
VAL G:597 G:597 61.0 0.394 H -72.6 -38.0 NA NA NA
3l3o 1 P01024 100.0 0.0 X-RAY
 2010-08-04 VAL A:597 A:597 51.0 0.329 H -69.5 -36.4 51.0 0.329 0.0
VAL F:597 D:597 49.0 0.316 H -69.4 -36.4 NA NA NA
3l5n 1 P01024 100.0 0.0 X-RAY
 2010-08-04 VAL A:597 A:597 62.0 0.4 H -104.5 -27.6 62.0 0.4 0.0
3nms 1 P01024 100.0 0.0 X-RAY
 2010-08-04 VAL A:597 A:597 50.0 0.323 H -69.5 -36.4 50.0 0.323 0.0
3ohx 1 P01024 100.0 0.0 X-RAY
 2010-09-01 VAL A:597 A:597 51.0 0.329 H -69.5 -36.3 51.0 0.329 0.0
VAL H:597 D:597 51.0 0.329 H -69.4 -36.4 NA NA NA
3t4a 1 P01024 100.0 0.0 X-RAY
 2011-11-23 VAL A:597 A:597 47.0 0.303 H -49.9 -45.8 47.0 0.303 0.0
VAL D:597 D:597 47.0 0.303 H -50.0 -45.8 NA NA NA
5fo7 1 P01024 100.0 0.0 X-RAY
 2016-04-06 VAL A:597 A:619 49.0 0.316 H -60.1 -46.5 49.0 0.316 0.0
5fo8 1 P01024 100.0 0.0 X-RAY
 2016-04-06 VAL A:597 A:619 55.0 0.355 H -55.8 -45.2 55.0 0.355 0.0 HOH
 2.912
 O
 O
5fo9 1 P01024 100.0 0.0 X-RAY
 2016-04-06 VAL A:597 A:619 51.0 0.329 H -58.7 -37.7 NA NA NA
VAL D:597 D:619 54.0 0.348 H -60.0 -38.3 54.0 0.348 0.0
5foa 1 P01024 100.0 0.0 X-RAY
 2016-04-06 VAL A:597 A:619 44.0 0.284 H -62.7 -55.6 44.0 0.284 0.0
VAL C:597 C:619 45.0 0.29 H -62.6 -55.8 NA NA NA
5fob 1 P01024 100.0 0.0 X-RAY
 2016-04-06 VAL A:597 A:619 44.0 0.284 H -55.7 -41.9 44.0 0.284 0.0 GOL
GOL
HOH
 5.515
8.434
4.487
 CG2
CG2
CG2
 O2
O2
O
5o32 1 P01024 100.0 0.0 X-RAY
 2017-06-28 VAL A:597 A:619 53.0 0.342 H -59.1 -45.3 53.0 0.342 0.0
VAL F:597 E:619 52.0 0.335 H -59.0 -45.4 52.0 0.335 0.0
5o35 1 P01024 100.0 0.0 X-RAY
 2017-06-28 VAL A:597 A:619 54.0 0.348 H -59.9 -46.0 54.0 0.348 0.0
6rur 3 P01024 100.0 0.0 X-RAY
 2019-08-21 VAL E:597 A:597 52.0 0.335 H -70.3 -33.1 52.0 0.335 0.0
VAL G:597 G:597 60.0 0.387 H -69.6 -32.9 60.0 0.387 0.0
6ruv 4 P01024 100.0 0.0 X-RAY
 2019-08-21 VAL G:597 A:597 49.0 0.316 H -68.5 -37.7 49.0 0.316 0.0
VAL I:597 G:597 49.0 0.316 H -68.5 -38.2 49.0 0.316 0.0
7bag 1 P01024 100.0 0.0 X-RAY
 2022-01-12 VAL A:597 A:597 56.0 0.361 H -61.0 -45.6 56.0 0.361 0.0 HOH
 2.918
 O
 O
6ru5 1 P01024 99.84 0.0 X-RAY
 2019-08-21 VAL A:597 A:619 38.0 0.245 H -66.9 -41.5 38.0 0.245 0.0
3g6j 1 P01024 100.0 0.0 X-RAY
 2009-03-10 VAL A:597 A:597 53.0 0.342 H -56.6 -49.5 53.0 0.342 0.0
VAL C:597 C:597 51.0 0.329 H -77.3 -43.6 NA NA NA
6yo6 1 ? 99.69 0.0 X-RAY
 2021-02-24 VAL A:597 A:619 37.0 0.239 H -68.7 -36.5 37.0 0.239 0.0
2i07 1 P01024 99.84 0.0 X-RAY
 2006-10-24 VAL A:597 A:597 52.0 0.335 H -63.5 -56.4 52.0 0.335 0.0
6ehg 1 P01024 99.69 0.0 X-RAY
 2018-02-14 VAL A:597 A:619 45.0 0.29 H -68.8 -36.4 45.0 0.29 0.0
2xwb 1 P01024 100.0 0.0 X-RAY
 2011-01-12 VAL A:597 A:597 57.0 0.368 H -69.1 -40.8 57.0 0.368 0.0
VAL C:597 C:597 54.0 0.348 H -68.8 -41.6 NA NA NA
2a73 1 P01024 99.84 0.0 X-RAY
 2005-09-27 VAL A:597 A:597 57.0 0.368 H -76.2 -25.1 57.0 0.368 0.0
2a74 1 P01024 99.84 0.0 X-RAY
 2005-09-27 VAL A:597 A:597 43.0 0.277 H -63.6 -39.0 43.0 0.277 0.0 GOL
HOH
 9.389
2.707
 N
O
 C3
O
VAL D:597 D:597 46.0 0.297 H -58.6 -49.4 NA NA NA
2qki 1 P01024 99.84 0.0 X-RAY
 2007-08-14 VAL A:597 A:597 56.0 0.361 H -70.8 -37.9 56.0 0.361 0.0 GOL
HOH
 4.654
5.678
 CG2
CG2
 O2
O
VAL D:597 D:597 55.0 0.355 H -65.8 -40.1 NA NA NA
2ice 1 P01024 99.84 0.0 X-RAY
 2006-11-07 VAL A:597 A:597 52.0 0.335 H -62.8 -53.5 52.0 0.335 0.0
VAL E:597 D:597 55.0 0.355 H -64.8 -49.2 NA NA NA
2icf 1 P01024 99.84 0.0 X-RAY
 2006-11-07 VAL A:597 A:597 37.0 0.239 H -48.4 -60.9 37.0 0.239 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p01024-f1 1 P01024 100.0 0.0 VAL A:619 A:619 49.0 0.316 H -81.4 -32.8