Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 6714193 . A C CCDS32883.1:NM_000064.2:c.666ttT>ttG_NP_000055.2:p.222F>L Homo sapiens complement component 3 (C3), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2wii 1 P01024 100.0 0.0 X-RAY
 2009-06-09 PHE A:200 A:200 1.0 0.005 E -141.0 134.9 1.0 0.005 0.0 HOH
 7.731
 CB
 O
2win 1 P01024 100.0 0.0 X-RAY
 2009-06-09 PHE A:200 A:200 0.0 0.0 E -138.8 128.5 0.0 0.0 0.0
PHE C:200 C:200 0.0 0.0 E -138.8 128.6 NA NA NA
PHE E:200 E:200 0.0 0.0 E -138.8 128.6 NA NA NA
PHE G:200 G:200 1.0 0.005 E -138.8 128.5 1.0 0.005 0.0
2xwj 1 P01024 100.0 0.0 X-RAY
 2011-01-12 PHE A:200 A:200 1.0 0.005 E -146.1 135.0 1.0 0.005 0.0
PHE C:200 C:200 1.0 0.005 E -146.0 135.2 NA NA NA
PHE E:200 E:200 1.0 0.005 E -146.1 135.2 NA NA NA
PHE G:200 G:200 1.0 0.005 E -146.5 135.1 NA NA NA
3l3o 1 P01024 100.0 0.0 X-RAY
 2010-08-04 PHE A:200 A:200 2.0 0.01 E -158.9 137.4 2.0 0.01 0.0
PHE F:200 D:200 2.0 0.01 E -158.9 137.3 NA NA NA
3l5n 1 P01024 100.0 0.0 X-RAY
 2010-08-04 PHE A:200 A:200 0.0 0.0 -139.5 128.9 0.0 0.0 0.0
3nms 1 P01024 100.0 0.0 X-RAY
 2010-08-04 PHE A:200 A:200 3.0 0.014 -158.8 137.3 3.0 0.014 0.0
3ohx 1 P01024 100.0 0.0 X-RAY
 2010-09-01 PHE A:200 A:200 2.0 0.01 E -159.0 137.4 2.0 0.01 0.0
PHE H:200 D:200 1.0 0.005 E -159.0 137.4 NA NA NA
3t4a 1 P01024 100.0 0.0 X-RAY
 2011-11-23 PHE A:200 A:200 1.0 0.005 E -155.5 138.9 1.0 0.005 0.0
PHE D:200 D:200 0.0 0.0 E -155.5 138.9 NA NA NA
5fo7 1 P01024 100.0 0.0 X-RAY
 2016-04-06 PHE A:200 A:222 0.0 0.0 E -145.9 134.3 0.0 0.0 0.0
5fo8 1 P01024 100.0 0.0 X-RAY
 2016-04-06 PHE A:200 A:222 2.0 0.01 E -142.8 142.7 2.0 0.01 0.0 HOH
 6.157
 CB
 O
5fo9 1 P01024 100.0 0.0 X-RAY
 2016-04-06 PHE A:200 A:222 1.0 0.005 E -149.2 145.5 NA NA NA
PHE D:200 D:222 0.0 0.0 E -150.0 146.6 0.0 0.0 0.0
5foa 1 P01024 100.0 0.0 X-RAY
 2016-04-06 PHE A:200 A:222 2.0 0.01 E -138.3 139.9 2.0 0.01 0.0
PHE C:200 C:222 2.0 0.01 E -137.8 141.1 NA NA NA
5fob 1 P01024 100.0 0.0 X-RAY
 2016-04-06 PHE A:200 A:222 0.0 0.0 E -145.3 144.5 0.0 0.0 0.0 GOL
GOL
HOH
 7.673
7.245
4.021
 N
N
CA
 O3
C3
O
5o32 1 P01024 100.0 0.0 X-RAY
 2017-06-28 PHE A:200 A:222 1.0 0.005 E -146.8 133.8 1.0 0.005 0.0
PHE F:200 E:222 1.0 0.005 E -146.6 133.9 1.0 0.005 0.0
5o35 1 P01024 100.0 0.0 X-RAY
 2017-06-28 PHE A:200 A:222 2.0 0.01 E -145.5 133.3 2.0 0.01 0.0
6rur 3 P01024 100.0 0.0 X-RAY
 2019-08-21 PHE E:200 A:200 4.0 0.019 E -143.5 167.2 4.0 0.019 0.0
PHE G:200 G:200 1.0 0.005 E -143.7 166.1 1.0 0.005 0.0
6ruv 4 P01024 100.0 0.0 X-RAY
 2019-08-21 PHE G:200 A:200 3.0 0.014 E -152.7 172.5 3.0 0.014 0.0
PHE I:200 G:200 3.0 0.014 E -152.7 171.5 3.0 0.014 0.0
7bag 1 P01024 100.0 0.0 X-RAY
 2022-01-12 PHE A:200 A:200 0.0 0.0 E -142.7 147.6 0.0 0.0 0.0 HOH
 3.883
 CA
 O
6ru5 1 P01024 99.84 0.0 X-RAY
 2019-08-21 PHE A:200 A:222 2.0 0.01 E -153.5 157.6 2.0 0.01 0.0
3g6j 1 P01024 100.0 0.0 X-RAY
 2009-03-10 PHE A:200 A:200 0.0 0.0 E -135.8 135.7 0.0 0.0 0.0
PHE C:200 C:200 2.0 0.01 E -148.0 138.4 NA NA NA
6yo6 1 ? 99.69 0.0 X-RAY
 2021-02-24 PHE A:200 A:222 0.0 0.0 E -145.9 135.7 0.0 0.0 0.0
2i07 1 P01024 99.84 0.0 X-RAY
 2006-10-24 PHE A:200 A:200 3.0 0.014 E -138.1 140.0 3.0 0.014 0.0
6ehg 1 P01024 99.69 0.0 X-RAY
 2018-02-14 PHE A:200 A:222 1.0 0.005 E -145.9 135.7 1.0 0.005 0.0
2xwb 1 P01024 100.0 0.0 X-RAY
 2011-01-12 PHE A:200 A:200 1.0 0.005 E -147.7 139.4 1.0 0.005 0.0
PHE C:200 C:200 2.0 0.01 E -147.3 139.6 NA NA NA
2a73 1 P01024 99.84 0.0 X-RAY
 2005-09-27 PHE A:200 A:200 1.0 0.005 E -149.5 159.0 1.0 0.005 0.0
2a74 1 P01024 99.84 0.0 X-RAY
 2005-09-27 PHE A:200 A:200 0.0 0.0 E -131.8 153.8 0.0 0.0 0.0 HOH
 4.005
 CA
 O
PHE D:200 D:200 0.0 0.0 E -144.4 151.0 NA NA NA
2qki 1 P01024 99.84 0.0 X-RAY
 2007-08-14 PHE A:200 A:200 0.0 0.0 E -142.8 157.0 0.0 0.0 0.0 GOL
HOH
 5.182
3.934
 CB
CA
 O3
O
PHE D:200 D:200 0.0 0.0 E -147.2 151.9 NA NA NA
2ice 1 P01024 99.84 0.0 X-RAY
 2006-11-07 PHE A:200 A:200 1.0 0.005 E -148.4 149.2 1.0 0.005 0.0
PHE E:200 D:200 1.0 0.005 E -148.9 144.9 NA NA NA
2icf 1 P01024 99.84 0.0 X-RAY
 2006-11-07 PHE A:200 A:200 0.0 0.0 E -169.0 126.8 0.0 0.0 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p01024-f1 1 P01024 100.0 0.0 PHE A:222 A:222 0.0 0.0 E -144.5 150.8