Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 6714373 . C A CCDS32883.1:NM_000064.2:c.589Gaa>Taa_NP_000055.2:p.197E>* Homo sapiens complement component 3 (C3), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2wii 1 P01024 100.0 0.0 X-RAY
 2009-06-09 GLU A:175 A:175 147.0 0.774 S -55.9 -40.3 114.0 0.6 0.174 B:P01024:0.174
 GOL
GOL
HOH
 6.782
9.469
7.629
 CB
OE2
N
 C1
C3
O
2win 1 P01024 100.0 0.0 X-RAY
 2009-06-09 GLU A:175 A:175 134.0 0.705 S -60.1 -44.3 81.0 0.426 0.279 B:P01024:0.279
GLU C:175 C:175 137.0 0.721 S -60.1 -44.4 NA NA NA
GLU E:175 E:175 136.0 0.716 S -60.1 -44.3 NA NA NA
GLU G:175 G:175 138.0 0.726 S -60.2 -44.3 85.0 0.447 0.279 H:P01024:0.279
2xwj 1 P01024 100.0 0.0 X-RAY
 2011-01-12 GLU A:175 A:175 143.0 0.753 S -56.6 -48.9 70.0 0.368 0.385 B:P01024:0.147
I:P00751:0.237
 NAG
 9.916
 O
 O6
GLU C:175 C:175 141.0 0.742 S -56.5 -49.0 NA NA NA
GLU E:175 E:175 143.0 0.753 S -56.1 -49.3 NA NA NA
GLU G:175 G:175 142.0 0.747 S -56.8 -49.0 NA NA NA
3l3o 1 P01024 100.0 0.0 X-RAY
 2010-08-04 GLU A:175 A:175 146.0 0.768 S -69.0 -49.4 120.0 0.632 0.136 B:P01024:0.137
GLU F:175 D:175 149.0 0.784 S -69.0 -49.4 NA NA NA
3l5n 1 P01024 100.0 0.0 X-RAY
 2010-08-04 GLU A:175 A:175 143.0 0.753 S -53.7 -47.7 76.0 0.4 0.353 B:P01024:0.353
3nms 1 P01024 100.0 0.0 X-RAY
 2010-08-04 GLU A:175 A:175 148.0 0.779 S -69.0 -49.3 122.0 0.642 0.137 D:P01024:0.137
3ohx 1 P01024 100.0 0.0 X-RAY
 2010-09-01 GLU A:175 A:175 149.0 0.784 S -69.0 -49.4 123.0 0.647 0.137 B:P01024:0.137
GLU H:175 D:175 149.0 0.784 S -69.0 -49.5 NA NA NA
3t4a 1 P01024 100.0 0.0 X-RAY
 2011-11-23 GLU A:175 A:175 145.0 0.763 S -62.2 -30.9 118.0 0.621 0.142 B:P01024:0.142
GLU D:175 D:175 146.0 0.768 S -62.2 -30.9 NA NA NA
5fo7 1 P01024 100.0 0.0 X-RAY
 2016-04-06 GLU A:175 A:197 147.0 0.774 S -64.5 -53.5 108.0 0.568 0.206 B:P01024:0.205
5fo8 1 P01024 100.0 0.0 X-RAY
 2016-04-06 GLU A:175 A:197 143.0 0.753 S -60.6 -42.2 112.0 0.589 0.164 B:P01024:0.163
 NAG
HOH
 9.186
3.069
 O
O
 O7
O
5fo9 1 P01024 100.0 0.0 X-RAY
 2016-04-06 GLU A:175 A:197 139.0 0.732 S -75.6 -34.5 NA NA NA
GLU D:175 D:197 141.0 0.742 S -76.4 -34.8 78.0 0.411 0.331 E:P01024:0.332
5foa 1 P01024 100.0 0.0 X-RAY
 2016-04-06 GLU A:175 A:197 131.0 0.689 S -66.6 -27.1 93.0 0.489 0.2 B:P01024:0.2
GLU C:175 C:197 147.0 0.774 S -65.8 -27.5 NA NA NA
5fob 1 P01024 100.0 0.0 X-RAY
 2016-04-06 GLU A:175 A:197 143.0 0.753 S -68.5 -37.2 96.0 0.505 0.248 B:P01024:0.247
 GOL
GOL
HOH
 9.830
7.947
3.123
 O
OE1
O
 O2
O3
O
5o32 1 P01024 100.0 0.0 X-RAY
 2017-06-28 GLU A:175 A:197 145.0 0.763 S -64.9 -55.0 70.0 0.368 0.395 B:P01024:0.089
E:P05156:0.305
GLU F:175 E:197 153.0 0.805 S -65.6 -56.5 63.0 0.332 0.473 J:P05156:0.337
G:P01024:0.168
5o35 1 P01024 100.0 0.0 X-RAY
 2017-06-28 GLU A:175 A:197 140.0 0.737 S -64.5 -54.0 114.0 0.6 0.137 B:P01024:0.137
6rur 3 P01024 100.0 0.0 X-RAY
 2019-08-21 GLU E:175 A:175 165.0 0.868 S -71.9 -33.8 86.0 0.453 0.415 F:P01024:0.416
GLU G:175 G:175 140.0 0.737 S -69.5 -33.9 52.0 0.274 0.463 H:P01024:0.463
6ruv 4 P01024 100.0 0.0 X-RAY
 2019-08-21 GLU G:175 A:175 161.0 0.847 S -74.9 -24.1 91.0 0.479 0.368 H:P01024:0.368
GLU I:175 G:175 155.0 0.816 S -74.4 -23.5 90.0 0.474 0.342 J:P01024:0.342
7bag 1 P01024 100.0 0.0 X-RAY
 2022-01-12 GLU A:175 A:175 139.0 0.732 S -68.6 -34.9 89.0 0.468 0.264 B:P01024:0.263
 HOH
 3.100
 OE2
 O
6ru5 1 P01024 99.84 0.0 X-RAY
 2019-08-21 GLU A:175 A:197 159.0 0.837 S -73.5 -24.2 136.0 0.716 0.121 B:P01024:0.121
3g6j 1 P01024 100.0 0.0 X-RAY
 2009-03-10 GLU A:175 A:175 133.0 0.7 S -70.9 -58.7 96.0 0.505 0.195 B:P01024:0.195
GLU C:175 C:175 147.0 0.774 S -64.4 -37.9 NA NA NA
6yo6 1 ? 99.69 0.0 X-RAY
 2021-02-24 GLU A:175 A:197 140.0 0.737 S -70.9 -44.9 68.0 0.358 0.379 B:None:0.379
2i07 1 P01024 99.84 0.0 X-RAY
 2006-10-24 GLU A:175 A:175 148.0 0.779 S -66.0 -27.2 80.0 0.421 0.358 B:P01024:0.358
6ehg 1 P01024 99.69 0.0 X-RAY
 2018-02-14 GLU A:175 A:197 139.0 0.732 S -70.9 -44.9 69.0 0.363 0.369 B:P01024:0.368
 NAG
 9.711
 O
 O7
2xwb 1 P01024 100.0 0.0 X-RAY
 2011-01-12 GLU A:175 A:175 137.0 0.721 T -60.4 -40.5 75.0 0.395 0.326 B:P01024:0.111
E:P00751:0.211
GLU C:175 C:175 138.0 0.726 T -60.7 -40.0 NA NA NA
2a73 1 P01024 99.84 0.0 X-RAY
 2005-09-27 GLU A:175 A:175 156.0 0.821 S -74.9 -7.0 125.0 0.658 0.163 B:P01024:0.163
2a74 1 P01024 99.84 0.0 X-RAY
 2005-09-27 GLU A:175 A:175 143.0 0.753 S -71.1 -31.8 109.0 0.574 0.179 B:P01024:0.179
 HOH
 3.158
 O
 O
GLU D:175 D:175 148.0 0.779 S -64.6 -36.1 NA NA NA
2qki 1 P01024 99.84 0.0 X-RAY
 2007-08-14 GLU A:175 A:175 137.0 0.721 S -58.3 -36.8 100.0 0.526 0.195 B:P01024:0.195
 BR
HOH
 8.744
6.174
 C
OE1
 BR
O
GLU D:175 D:175 142.0 0.747 S -75.2 -33.4 NA NA NA
2ice 1 P01024 99.84 0.0 X-RAY
 2006-11-07 GLU A:175 A:175 144.0 0.758 S -61.9 -42.7 114.0 0.6 0.158 B:P01024:0.158
GLU E:175 D:175 145.0 0.763 S -66.3 -45.1 NA NA NA
2icf 1 P01024 99.84 0.0 X-RAY
 2006-11-07 GLU A:175 A:175 156.0 0.821 S -69.3 -17.8 135.0 0.711 0.11 B:P01024:0.111
 NAG
 9.187
 O
 O4

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p01024-f1 1 P01024 100.0 0.0 GLU A:197 A:197 110.0 0.579 S -54.5 -23.6