Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr19 | 6719225 | . | G | A | CCDS32883.1:NM_000064.2:c.264ttC>ttT_NP_000055.2:p.88F>F | Homo sapiens complement component 3 (C3), mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 2wii | 1 | P01024 | 100.0 | 0.0 |
X-RAY |
2009-06-09 | PHE | A:66 | A:66 | 4.0 | 0.019 | E | -137.8 | 143.1 | 4.0 | 0.019 | 0.0 |
NAG HOH |
9.498 6.238 |
N N |
C1 O |
||
| 2win | 1 | P01024 | 100.0 | 0.0 |
X-RAY |
2009-06-09 | PHE | A:66 | A:66 | 2.0 | 0.01 | E | -118.8 | 168.3 | 2.0 | 0.01 | 0.0 | ||||||
| PHE | C:66 | C:66 | 2.0 | 0.01 | E | -118.8 | 168.3 | NA | NA | NA | |||||||||||||
| PHE | E:66 | E:66 | 1.0 | 0.005 | E | -118.8 | 168.2 | NA | NA | NA | |||||||||||||
| PHE | G:66 | G:66 | 3.0 | 0.014 | E | -118.8 | 168.3 | 3.0 | 0.014 | 0.0 |
NAG |
9.579 |
N |
O5 |
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| 2xwj | 1 | P01024 | 100.0 | 0.0 |
X-RAY |
2011-01-12 | PHE | A:66 | A:66 | 1.0 | 0.005 | E | -105.8 | 156.5 | 1.0 | 0.005 | 0.0 | ||||||
| PHE | C:66 | C:66 | 1.0 | 0.005 | E | -107.5 | 153.2 | NA | NA | NA | |||||||||||||
| PHE | E:66 | E:66 | 0.0 | 0.0 | E | -107.0 | 153.4 | NA | NA | NA | |||||||||||||
| PHE | G:66 | G:66 | 1.0 | 0.005 | E | -105.4 | 156.3 | NA | NA | NA | |||||||||||||
| 3l3o | 1 | P01024 | 100.0 | 0.0 |
X-RAY |
2010-08-04 | PHE | A:66 | A:66 | 9.0 | 0.043 | E | -150.2 | 156.3 | 9.0 | 0.043 | 0.0 |
NAG |
9.861 |
N |
O7 |
||
| PHE | F:66 | D:66 | 9.0 | 0.043 | E | -150.2 | 156.3 | NA | NA | NA | |||||||||||||
| 3l5n | 1 | P01024 | 100.0 | 0.0 |
X-RAY |
2010-08-04 | PHE | A:66 | A:66 | 25.0 | 0.119 | -131.2 | 171.2 | 25.0 | 0.119 | 0.0 |
NAG |
7.591 |
N |
C6 |
|||
| 3nms | 1 | P01024 | 100.0 | 0.0 |
X-RAY |
2010-08-04 | PHE | A:66 | A:66 | 9.0 | 0.043 | E | -150.2 | 156.3 | 9.0 | 0.043 | 0.0 |
NAG |
9.861 |
N |
O7 |
||
| 3ohx | 1 | P01024 | 100.0 | 0.0 |
X-RAY |
2010-09-01 | PHE | A:66 | A:66 | 7.0 | 0.033 | E | -150.2 | 156.3 | 7.0 | 0.033 | 0.0 |
NAG |
9.862 |
N |
O7 |
||
| PHE | H:66 | D:66 | 7.0 | 0.033 | E | -150.2 | 156.3 | NA | NA | NA | |||||||||||||
| 3t4a | 1 | P01024 | 100.0 | 0.0 |
X-RAY |
2011-11-23 | PHE | A:66 | A:66 | 1.0 | 0.005 | E | -122.1 | 159.5 | 1.0 | 0.005 | 0.0 | ||||||
| PHE | D:66 | D:66 | 1.0 | 0.005 | E | -122.1 | 159.5 | NA | NA | NA | |||||||||||||
| 5fo7 | 1 | P01024 | 100.0 | 0.0 |
X-RAY |
2016-04-06 | PHE | A:66 | A:88 | 4.0 | 0.019 | E | -144.4 | 148.5 | 4.0 | 0.019 | 0.0 |
NAG |
9.614 |
N |
O7 |
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| 5fo8 | 1 | P01024 | 100.0 | 0.0 |
X-RAY |
2016-04-06 | PHE | A:66 | A:88 | 3.0 | 0.014 | E | -145.9 | 161.6 | 3.0 | 0.014 | 0.0 |
NAG HOH |
9.468 3.522 |
N CA |
C1 O |
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| 5fo9 | 1 | P01024 | 100.0 | 0.0 |
X-RAY |
2016-04-06 | PHE | A:66 | A:88 | 9.0 | 0.043 | E | -133.3 | 153.4 | NA | NA | NA | ||||||
| PHE | D:66 | D:88 | 6.0 | 0.029 | E | -133.6 | 154.0 | 6.0 | 0.029 | 0.0 |
NAG |
9.273 |
N |
C1 |
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| 5foa | 1 | P01024 | 100.0 | 0.0 |
X-RAY |
2016-04-06 | PHE | A:66 | A:88 | 5.0 | 0.024 | E | -128.0 | 161.3 | 5.0 | 0.024 | 0.0 | ||||||
| PHE | C:66 | C:88 | 5.0 | 0.024 | E | -128.5 | 159.7 | NA | NA | NA | |||||||||||||
| 5fob | 1 | P01024 | 100.0 | 0.0 |
X-RAY |
2016-04-06 | PHE | A:66 | A:88 | 6.0 | 0.029 | E | -143.8 | 150.0 | 6.0 | 0.029 | 0.0 |
NAG IOD HOH |
7.615 8.521 9.876 |
N O N |
C8 I O |
||
| 5o32 | 1 | P01024 | 100.0 | 0.0 |
X-RAY |
2017-06-28 | PHE | A:66 | A:88 | 5.0 | 0.024 | E | -144.7 | 149.1 | 5.0 | 0.024 | 0.0 |
NAG |
9.317 |
N |
C8 |
||
| PHE | F:66 | E:88 | 5.0 | 0.024 | E | -144.1 | 149.1 | 5.0 | 0.024 | 0.0 |
NAG |
9.666 |
N |
C1 |
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| 5o35 | 1 | P01024 | 100.0 | 0.0 |
X-RAY |
2017-06-28 | PHE | A:66 | A:88 | 5.0 | 0.024 | E | -144.6 | 149.1 | 5.0 | 0.024 | 0.0 | ||||||
| 6rur | 3 | P01024 | 100.0 | 0.0 |
X-RAY |
2019-08-21 | PHE | E:66 | A:66 | 12.0 | 0.057 | E | -155.0 | 169.5 | 12.0 | 0.057 | 0.0 | ||||||
| PHE | G:66 | G:66 | 6.0 | 0.029 | E | -154.1 | 168.3 | 6.0 | 0.029 | 0.0 | |||||||||||||
| 6ruv | 4 | P01024 | 100.0 | 0.0 |
X-RAY |
2019-08-21 | PHE | G:66 | A:66 | 19.0 | 0.09 | E | -154.1 | 175.9 | 19.0 | 0.09 | 0.0 | ||||||
| PHE | I:66 | G:66 | 15.0 | 0.071 | E | -154.1 | 175.9 | 15.0 | 0.071 | 0.0 | |||||||||||||
| 7bag | 1 | P01024 | 100.0 | 0.0 |
X-RAY |
2022-01-12 | PHE | A:66 | A:66 | 8.0 | 0.038 | E | -166.0 | 174.8 | 8.0 | 0.038 | 0.0 |
NAG HOH |
9.542 4.074 |
N CA |
C1 O |
||
| 6ru5 | 1 | P01024 | 99.84 | 0.0 |
X-RAY |
2019-08-21 | PHE | A:66 | A:88 | 5.0 | 0.024 | B | -155.1 | 155.2 | 5.0 | 0.024 | 0.0 | ||||||
| 3g6j | 1 | P01024 | 100.0 | 0.0 |
X-RAY |
2009-03-10 | PHE | A:66 | A:66 | 4.0 | 0.019 | E | -134.7 | 159.4 | 4.0 | 0.019 | 0.0 | ||||||
| PHE | C:66 | C:66 | 6.0 | 0.029 | E | -155.9 | 166.5 | NA | NA | NA | |||||||||||||
| 6yo6 | 1 | ? | 99.69 | 0.0 |
X-RAY |
2021-02-24 | PHE | A:66 | A:88 | 5.0 | 0.024 | E | -122.5 | 175.6 | 5.0 | 0.024 | 0.0 | ||||||
| 2i07 | 1 | P01024 | 99.84 | 0.0 |
X-RAY |
2006-10-24 | PHE | A:66 | A:66 | 1.0 | 0.005 | E | -128.5 | 160.0 | 1.0 | 0.005 | 0.0 |
NAG NAG |
9.057 9.461 |
N N |
C1 C8 |
||
| 6ehg | 1 | P01024 | 99.69 | 0.0 |
X-RAY |
2018-02-14 | PHE | A:66 | A:88 | 5.0 | 0.024 | E | -122.6 | 175.6 | 5.0 | 0.024 | 0.0 |
NAG |
9.794 |
N |
C1 |
||
| 2xwb | 1 | P01024 | 100.0 | 0.0 |
X-RAY |
2011-01-12 | PHE | A:66 | A:66 | 3.0 | 0.014 | E | -126.1 | 161.0 | 3.0 | 0.014 | 0.0 | ||||||
| PHE | C:66 | C:66 | 3.0 | 0.014 | E | -124.6 | 160.9 | NA | NA | NA | |||||||||||||
| 2a73 | 1 | P01024 | 99.84 | 0.0 |
X-RAY |
2005-09-27 | PHE | A:66 | A:66 | 12.0 | 0.057 | E | -154.3 | 155.4 | 12.0 | 0.057 | 0.0 |
NAG |
9.722 |
N |
C8 |
||
| 2a74 | 1 | P01024 | 99.84 | 0.0 |
X-RAY |
2005-09-27 | PHE | A:66 | A:66 | 1.0 | 0.005 | E | -138.4 | 155.0 | 1.0 | 0.005 | 0.0 |
NDG HOH |
9.271 4.234 |
N O |
C1 O |
||
| PHE | D:66 | D:66 | 3.0 | 0.014 | E | -134.7 | 179.0 | NA | NA | NA | |||||||||||||
| 2qki | 1 | P01024 | 99.84 | 0.0 |
X-RAY |
2007-08-14 | PHE | A:66 | A:66 | 4.0 | 0.019 | E | -125.0 | 158.8 | 4.0 | 0.019 | 0.0 |
NAG HOH |
9.721 4.819 |
N N |
C1 O |
||
| PHE | D:66 | D:66 | 4.0 | 0.019 | E | -127.5 | 155.3 | NA | NA | NA | |||||||||||||
| 2ice | 1 | P01024 | 99.84 | 0.0 |
X-RAY |
2006-11-07 | PHE | A:66 | A:66 | 1.0 | 0.005 | E | -120.7 | 166.5 | 1.0 | 0.005 | 0.0 |
NAG |
9.105 |
N |
C1 |
||
| PHE | E:66 | D:66 | 14.0 | 0.067 | E | -165.4 | 165.3 | NA | NA | NA | |||||||||||||
| 2icf | 1 | P01024 | 99.84 | 0.0 |
X-RAY |
2006-11-07 | PHE | A:66 | A:66 | 4.0 | 0.019 | E | -134.5 | 162.9 | 4.0 | 0.019 | 0.0 |
NAG |
9.268 |
N |
O5 |
||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p01024-f1 | 1 | P01024 | 100.0 | 0.0 | PHE | A:88 | A:88 | 4.0 | 0.019 | E | -139.4 | 162.2 | |