Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr20 6759611 . A C CCDS13099.1:NM_001200.2:c.1066Att>Ctt_NP_001191.1:p.356I>L Homo sapiens bone morphogenetic protein 2 (BMP2), mRNA.
pdb_id: 
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label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1es7 1 P12643 100.0 1e-82 X-RAY
 2000-10-07 ILE A:76 A:74 69.0 0.394 S -86.3 126.0 24.0 0.137 0.257 C:P12643:0.257
 HOH
 6.853
 O
 O
ILE C:76 C:574 69.0 0.394 S -88.8 127.3 24.0 0.137 0.257 A:P12643:0.257
 HOH
 6.805
 O
 O
2qj9 1 P12643 100.0 1e-82 X-RAY
 2008-01-15 ILE A:76 B:74 62.0 0.354 S -104.6 120.7 13.0 0.074 0.28 B:P12643:0.28
 HOH
 3.844
 C
 O
ILE B:76 A:74 59.0 0.337 S -98.1 125.0 12.0 0.069 0.268 A:P12643:0.269
 HOH
 5.467
 O
 O
2qja 1 P12643 100.0 1e-82 X-RAY
 2008-01-15 ILE A:76 A:74 61.0 0.349 S -118.8 125.3 13.0 0.074 0.275 B:P12643:0.274
 HOH
 5.448
 CD1
 O
ILE B:76 B:74 65.0 0.371 S -95.1 121.1 14.0 0.08 0.291 A:P12643:0.291
 HOH
 6.277
 CD1
 O
2qjb 1 P12643 100.0 1e-82 X-RAY
 2008-01-15 ILE A:76 A:74 57.0 0.326 S -105.2 113.0 11.0 0.063 0.263 B:P12643:0.263
 HOH
 7.646
 CG2
 O
ILE B:76 B:74 58.0 0.331 S -91.0 125.3 13.0 0.074 0.257 A:P12643:0.257
 HOH
 6.802
 CG1
 O
1rew 1 P12643 100.0 2e-82 X-RAY
 2004-05-04 ILE A:74 A:74 73.0 0.417 S -88.1 123.6 27.0 0.154 0.263 B:P12643:0.263
 HOH
 5.215
 O
 O
ILE B:74 B:74 62.0 0.354 S -93.0 123.7 16.0 0.091 0.263 A:P12643:0.263
 HOH
 3.994
 CG1
 O
2goo 1 P12643 100.0 2e-82 X-RAY
 2006-05-09 ILE A:74 A:74 74.0 0.423 S -79.9 119.6 74.0 0.423 0.0 HOH
 4.446
 C
 O
ILE D:74 D:74 65.0 0.371 S -79.6 120.0 65.0 0.371 0.0 HOH
 4.694
 O
 O
2h62 1 P12643 100.0 2e-82 X-RAY
 2007-04-10 ILE A:74 A:74 62.0 0.354 S -95.0 122.4 14.0 0.08 0.274 B:P12643:0.274
 HOH
 3.996
 CD1
 O
ILE B:74 B:74 64.0 0.366 S -94.9 121.5 19.0 0.109 0.257 A:P12643:0.257
 HOH
 3.686
 CD1
 O
3bmp 1 P12643 100.0 2e-82 X-RAY
 2000-03-12 ILE A:74 A:74 66.0 0.377 S -105.7 127.4 15.0 0.086 0.291 A:P12643:0.291
 HOH
 4.524
 CD1
 O
4uhy 1 P12643 100.0 2e-82 X-RAY
 2015-05-06 ILE A:74 A:356 68.0 0.389 S -87.8 115.7 16.0 0.091 0.298 B:P12643:0.297
ILE B:74 B:356 67.0 0.383 S -87.9 117.1 15.0 0.086 0.297 A:P12643:0.297
4uhz 1 P12643 100.0 2e-82 X-RAY
 2015-05-06 ILE A:74 A:356 70.0 0.4 S -89.2 121.9 70.0 0.4 0.0 SO4
 4.641
 O
 O1
4ui0 1 P12643 100.0 2e-82 X-RAY
 2015-05-06 ILE A:74 A:356 67.0 0.383 S -95.0 120.0 17.0 0.097 0.286 B:P12643:0.286
 HOH
 6.961
 CG1
 O
ILE B:74 B:356 66.0 0.377 S -93.9 120.2 18.0 0.103 0.274 A:P12643:0.274
 HOH
 7.936
 CG2
 O
4ui1 1 P12643 100.0 2e-82 X-RAY
 2015-05-06 ILE A:74 A:356 65.0 0.371 S -86.6 118.4 65.0 0.371 0.0 HOH
 4.487
 CG1
 O
ILE B:74 B:356 65.0 0.371 S -87.3 118.6 NA NA NA
4ui2 2 P12643 100.0 2e-82 X-RAY
 2015-05-06 ILE B:74 B:356 68.0 0.389 S -81.5 125.7 17.0 0.097 0.292 B:P12643:0.291
2h64 1 P12643 98.25 8e-81 X-RAY
 2007-04-10 ILE A:74 A:74 50.0 0.286 S -91.1 121.4 5.0 0.029 0.257 A:P12643:0.257
 HOH
 3.725
 CD1
 O
3bk3 1 P12643 98.25 1e-80 X-RAY
 2008-05-27 ILE A:74 A:74 61.0 0.349 S -106.1 118.9 9.0 0.051 0.298 B:P12643:0.297
 HOH
 7.199
 CG2
 O
ILE B:74 B:74 65.0 0.371 S -85.6 121.1 12.0 0.069 0.302 A:P12643:0.303
 HOH
 5.834
 CD1
 O
6omn 1 P12643 100.0 1e-77 X-RAY
 2019-05-08 ILE A:68 E:74 57.0 0.326 S -92.6 119.1 13.0 0.074 0.252 B:P12643:0.251
ILE B:68 F:74 65.0 0.371 S -86.8 125.5 13.0 0.074 0.297 A:P12643:0.297
 HOH
 4.222
 N
 O
ILE C:68 G:74 57.0 0.326 S -94.6 126.6 NA NA NA
ILE D:68 H:74 66.0 0.377 S -103.5 119.1 NA NA NA
1reu 1 P12643 99.03 2e-75 X-RAY
 2004-05-04 ILE A:63 A:74 50.0 0.286 S -95.0 121.3 10.0 0.057 0.229 A:P12643:0.229
 HOH
 7.512
 CG2
 O
4mid 1 ? 81.42 2e-68 X-RAY
 2014-05-07 ILE A:75 A:74 65.0 0.371 S -88.1 125.4 9.0 0.051 0.32 A:None:0.32
 HOH
 4.929
 CG1
 O
6oml 1 ? 85.71 9e-65 X-RAY
 2019-05-15 VAL A:65 X:74 30.0 0.194 S -109.9 127.4 1.0 0.006 0.188 B:None:0.187
 HOH
 4.263
 O
 O
VAL B:65 Y:74 24.0 0.155 S -105.8 122.9 1.0 0.006 0.149 A:None:0.148
 HOH
 6.763
 CG1
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p12643-f1 1 P12643 100.0 0.0 ILE A:356 A:356 50.0 0.286 S -82.4 135.9