Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr20 | 6759732 | . | G | A | CCDS13099.1:NM_001200.2:c.1187cGc>cAc_NP_001191.1:p.396R>H | Homo sapiens bone morphogenetic protein 2 (BMP2), mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 1es7 | 1 | P12643 | 100.0 | 1e-82 |
X-RAY |
2000-10-07 | ARG | A:116 | A:114 | 109.0 | 0.484 | -128.8 | 360.0 | 72.0 | 0.32 | 0.164 |
C:P12643:0.164 |
HOH |
2.576 |
O |
O |
||
| ARG | C:116 | C:614 | 110.0 | 0.489 | -124.8 | 360.0 | 72.0 | 0.32 | 0.169 |
A:P12643:0.169 |
HOH |
2.600 |
O |
O |
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| 2qj9 | 1 | P12643 | 100.0 | 1e-82 |
X-RAY |
2008-01-15 | ARG | A:116 | B:114 | 117.0 | NA | -127.3 | 360.0 | 75.0 | NA | NA |
B:P12643:NA |
HOH |
2.576 |
OXT |
O |
||
| ARG | B:116 | A:114 | 114.0 | NA | -127.8 | 360.0 | 72.0 | NA | NA |
A:P12643:NA |
HOH |
2.457 |
OXT |
O |
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| 2qja | 1 | P12643 | 100.0 | 1e-82 |
X-RAY |
2008-01-15 | ARG | A:116 | A:114 | 110.0 | NA | -132.4 | 360.0 | 69.0 | NA | NA |
B:P12643:NA |
HOH |
2.704 |
OXT |
O |
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| ARG | B:116 | B:114 | 114.0 | NA | -116.2 | 360.0 | 72.0 | NA | NA |
A:P12643:NA |
HOH |
2.495 |
OXT |
O |
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| 2qjb | 1 | P12643 | 100.0 | 1e-82 |
X-RAY |
2008-01-15 | ARG | A:116 | A:114 | 113.0 | NA | -133.1 | 360.0 | 74.0 | NA | NA |
B:P12643:NA |
CL HOH |
4.579 2.645 |
CG OXT |
CL O |
||
| ARG | B:116 | B:114 | 115.0 | NA | -149.3 | 360.0 | 78.0 | NA | NA |
A:P12643:NA |
CL HOH |
3.926 2.263 |
NH1 OXT |
CL O |
|||||||||
| 1rew | 1 | P12643 | 100.0 | 2e-82 |
X-RAY |
2004-05-04 | ARG | A:114 | A:114 | 123.0 | NA | -135.1 | 360.0 | 80.0 | NA | NA |
B:P12643:NA |
HOH |
2.505 |
OXT |
O |
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| ARG | B:114 | B:114 | 117.0 | NA | -132.4 | 360.0 | 74.0 | NA | NA |
A:P12643:NA |
HOH |
2.537 |
OXT |
O |
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| 2goo | 1 | P12643 | 100.0 | 2e-82 |
X-RAY |
2006-05-09 | ARG | A:114 | A:114 | 115.0 | NA | -134.8 | 360.0 | 115.0 | NA | NA |
HOH |
2.396 |
OXT |
O |
|||
| ARG | D:114 | D:114 | 121.0 | NA | -128.9 | 360.0 | 121.0 | NA | NA |
HOH |
2.561 |
OXT |
O |
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| 2h62 | 1 | P12643 | 100.0 | 2e-82 |
X-RAY |
2007-04-10 | ARG | A:114 | A:114 | 94.0 | NA | -131.1 | 360.0 | 49.0 | NA | NA |
B:P12643:NA |
HOH |
2.635 |
OXT |
O |
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| ARG | B:114 | B:114 | 117.0 | NA | -128.4 | 360.0 | 70.0 | NA | NA |
A:P12643:NA |
HOH |
2.538 |
OXT |
O |
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| 3bmp | 1 | P12643 | 100.0 | 2e-82 |
X-RAY |
2000-03-12 | ARG | A:114 | A:114 | 92.0 | NA | -138.5 | 360.0 | 53.0 | NA | NA |
A:P12643:NA |
HOH |
2.685 |
O |
O |
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| 4uhy | 1 | P12643 | 100.0 | 2e-82 |
X-RAY |
2015-05-06 | ARG | A:114 | A:396 | 103.0 | NA | -138.3 | 360.0 | 64.0 | NA | NA |
B:P12643:NA |
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| ARG | B:114 | B:396 | 102.0 | NA | -134.8 | 360.0 | 59.0 | NA | NA |
A:P12643:NA |
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| 4uhz | 1 | P12643 | 100.0 | 2e-82 |
X-RAY |
2015-05-06 | ARG | A:114 | A:396 | 106.0 | NA | -134.3 | 360.0 | 106.0 | NA | NA | |||||||
| 4ui0 | 1 | P12643 | 100.0 | 2e-82 |
X-RAY |
2015-05-06 | ARG | A:114 | A:396 | 103.0 | NA | -130.3 | 360.0 | 60.0 | NA | NA |
B:P12643:NA |
CL HOH |
4.583 2.713 |
CG O |
CL O |
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| ARG | B:114 | B:396 | 102.0 | NA | -129.6 | 360.0 | 60.0 | NA | NA |
A:P12643:NA |
CL HOH |
3.830 2.583 |
CG O |
CL O |
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| 4ui1 | 1 | P12643 | 100.0 | 2e-82 |
X-RAY |
2015-05-06 | ARG | A:114 | A:396 | 124.0 | NA | -127.0 | 360.0 | 124.0 | NA | NA |
NO3 HOH |
7.888 2.565 |
NH1 O |
O2 O |
|||
| ARG | B:114 | B:396 | 109.0 | NA | -121.7 | 360.0 | NA | NA | NA | ||||||||||||||
| 4ui2 | 2 | P12643 | 100.0 | 2e-82 |
X-RAY |
2015-05-06 | ARG | B:114 | B:396 | 111.0 | NA | -140.0 | 360.0 | 64.0 | NA | NA |
B:P12643:NA |
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| 2h64 | 1 | P12643 | 98.25 | 8e-81 |
X-RAY |
2007-04-10 | ARG | A:114 | A:114 | 113.0 | NA | -131.7 | 360.0 | 66.0 | NA | NA |
A:P12643:NA |
HOH |
2.584 |
OXT |
O |
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| 3bk3 | 1 | P12643 | 98.25 | 1e-80 |
X-RAY |
2008-05-27 | ARG | A:114 | A:114 | 98.0 | NA | -132.9 | 360.0 | 55.0 | NA | NA |
B:P12643:NA |
HOH |
2.790 |
OXT |
O |
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| ARG | B:114 | B:114 | 103.0 | NA | -129.4 | 360.0 | 60.0 | NA | NA |
A:P12643:NA |
HOH |
2.690 |
OXT |
O |
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| 6omn | 1 | P12643 | 100.0 | 1e-77 |
X-RAY |
2019-05-08 | ARG | A:108 | E:114 | 111.0 | NA | -124.6 | 360.0 | 73.0 | NA | NA |
B:P12643:NA |
NAG HOH |
7.010 7.510 |
NH2 CG |
O5 O |
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| ARG | B:108 | F:114 | 116.0 | NA | -126.1 | 360.0 | 70.0 | NA | NA |
A:P12643:NA |
NAG HOH |
7.826 3.090 |
NH2 OXT |
O5 O |
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| ARG | C:108 | G:114 | 117.0 | NA | -137.2 | 360.0 | NA | NA | NA | ||||||||||||||
| ARG | D:108 | H:114 | 118.0 | NA | -133.2 | 360.0 | NA | NA | NA | ||||||||||||||
| 1reu | 1 | P12643 | 99.03 | 2e-75 |
X-RAY |
2004-05-04 | ARG | A:103 | A:114 | 101.0 | NA | -136.0 | 360.0 | 58.0 | NA | NA |
A:P12643:NA |
HOH |
2.638 |
O |
O |
||
| 6oml | 1 | ? | 85.71 | 9e-65 |
X-RAY |
2019-05-15 | ARG | A:105 | X:114 | 85.0 | 0.378 | -126.3 | 360.0 | 49.0 | 0.218 | 0.16 |
B:None:0.16 |
NAG HOH |
4.816 2.676 |
NH1 O |
O5 O |
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| ARG | B:105 | Y:114 | 116.0 | 0.516 | -131.1 | 360.0 | 68.0 | 0.302 | 0.214 |
A:None:0.213 |
NAG HOH |
7.732 2.764 |
NH2 O |
C1 O |
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AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p12643-f1 | 1 | P12643 | 100.0 | 0.0 | ARG | A:396 | A:396 | 102.0 | 0.453 | -123.5 | 360.0 | ||