Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr21 42615361 . A C CCDS13668.1:NM_012105.4:c.806aAg>aCg_NP_036237.2:p.269K>T Homo sapiens beta-site APP-cleaving enzyme 2 (BACE2), transcript variant a, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6uj0 1 Q9Y5Z0 99.78 0.0 X-RAY
 2020-10-07 LYS A:269 A:207 70.0 0.35 S -74.0 -34.8 70.0 0.35 0.0 HOH
 2.491
 NZ
 O
LYS B:269 B:207 78.0 0.39 E -87.6 -24.8 NA NA NA
6uj1 1 Q9Y5Z0 99.78 0.0 X-RAY
 2020-10-07 LYS A:269 A:207 96.0 0.48 E -72.8 -26.3 96.0 0.48 0.0
LYS B:269 B:207 84.0 0.42 E -69.8 -37.1 NA NA NA
3zkm 1 Q9Y5Z0 100.0 0.0 X-RAY
 2013-05-29 LYS A:195 A:207 64.0 0.32 S -79.3 -33.4 64.0 0.32 0.0 HOH
 3.180
 NZ
 O
LYS B:195 B:207 67.0 0.335 S -80.3 -38.3 NA NA NA
3zkn 1 Q9Y5Z0 100.0 0.0 X-RAY
 2013-05-29 LYS A:195 A:207 73.0 0.365 S -91.9 -20.7 NA NA NA
LYS B:195 B:207 70.0 0.35 S -80.9 -35.9 70.0 0.35 0.0 HOH
 3.481
 NZ
 O
3zkq 1 Q9Y5Z0 100.0 0.0 X-RAY
 2013-05-29 LYS A:195 A:207 69.0 0.345 S -75.0 -35.0 69.0 0.345 0.0 HOH
 2.822
 O
 O
3zks 1 Q9Y5Z0 100.0 0.0 X-RAY
 2013-05-29 LYS A:195 A:207 64.0 0.32 S -83.1 -29.5 64.0 0.32 0.0 HOH
 3.574
 CD
 O
4bel 1 Q9Y5Z0 100.0 0.0 X-RAY
 2013-05-29 LYS A:195 A:207 82.0 0.41 E -79.1 -38.1 82.0 0.41 0.0 HOH
 2.852
 O
 O
LYS B:195 B:207 72.0 0.36 S -80.2 -33.5 NA NA NA
4bfb 1 Q9Y5Z0 100.0 0.0 X-RAY
 2013-05-29 LYS A:195 A:207 64.0 0.32 S -78.6 -36.6 64.0 0.32 0.0 HOH
 2.676
 NZ
 O
LYS B:195 B:207 73.0 0.365 -90.5 -35.2 NA NA NA
6jsz 1 Q9Y5Z0 100.0 0.0 X-RAY
 2019-08-28 LYS A:195 A:207 75.0 0.375 E -70.8 -36.3 75.0 0.375 0.0 HOH
 2.766
 NZ
 O
7d5b 1 Q9Y5Z0 100.0 0.0 X-RAY
 2021-03-31 LYS A:195 A:207 74.0 0.37 E -71.2 -31.5 74.0 0.37 0.0 HOH
 2.740
 NZ
 O
7d5u 1 Q9Y5Z0 100.0 0.0 X-RAY
 2021-03-31 LYS A:195 A:207 81.0 0.405 S -80.3 -20.9 81.0 0.405 0.0 HOH
 3.813
 CD
 O
7n4n 1 Q9Y5Z0 100.0 0.0 X-RAY
 2021-10-06 LYS A:195 A:207 71.0 0.355 S -73.2 -35.1 71.0 0.355 0.0 HOH
 1.821
 HZ3
 O
3zkg 1 Q9Y5Z0 99.74 0.0 X-RAY
 2013-05-29 LYS A:195 A:207 78.0 0.39 E -81.0 -26.8 78.0 0.39 0.0 HOH
 2.948
 NZ
 O
LYS B:195 B:207 75.0 0.375 S -78.2 -29.0 NA NA NA
3zki 1 Q9Y5Z0 99.74 0.0 X-RAY
 2013-05-29 LYS A:195 A:207 77.0 0.385 S -89.0 -27.8 77.0 0.385 0.0 HOH
 2.793
 NZ
 O
LYS B:195 B:207 75.0 0.375 S -79.4 -28.6 NA NA NA
3zkx 1 Q9Y5Z0 99.74 0.0 X-RAY
 2013-05-29 LYS A:195 A:207 71.0 0.355 S -77.6 -31.9 71.0 0.355 0.0 HOH
 2.977
 NZ
 O
3zl7 1 Q9Y5Z0 99.74 0.0 X-RAY
 2013-05-29 LYS A:195 A:207 74.0 0.37 E -74.6 -45.7 74.0 0.37 0.0
3zlq 1 Q9Y5Z0 99.74 0.0 X-RAY
 2013-05-01 LYS A:195 A:207 67.0 0.335 E -86.9 -26.9 67.0 0.335 0.0 HOH
 4.291
 CG
 O
LYS B:195 B:207 70.0 0.35 E -80.7 -31.4 70.0 0.35 0.0 HOH
 4.010
 CD
 O
2ewy 1 Q9Y5Z0 100.0 0.0 X-RAY
 2006-11-07 LYS A:192 A:207 68.0 0.34 S -66.7 -56.0 68.0 0.34 0.0 HOH
 3.066
 O
 O
LYS B:192 B:207 68.0 0.34 S -66.8 -55.9 NA NA NA
LYS C:192 C:207 67.0 0.335 S -66.7 -56.0 NA NA NA
LYS D:192 D:207 67.0 0.335 S -66.7 -55.9 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q9y5z0-f1 1 Q9Y5Z0 100.0 0.0 LYS A:269 A:269 75.0 0.375 S -81.4 -38.8