Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr21 42617959 . C A CCDS13668.1:NM_012105.4:c.953gCg>gAg_NP_036237.2:p.318A>E Homo sapiens beta-site APP-cleaving enzyme 2 (BACE2), transcript variant a, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6uj0 1 Q9Y5Z0 99.78 0.0 X-RAY
 2020-10-07 ALA A:318 A:256 22.0 0.191 H -65.3 -40.6 22.0 0.191 0.0 HOH
 2.686
 O
 O
ALA B:318 B:256 17.0 0.148 H -62.4 -41.9 NA NA NA
6uj1 1 Q9Y5Z0 99.78 0.0 X-RAY
 2020-10-07 ALA A:318 A:256 22.0 0.191 H -63.5 -36.8 22.0 0.191 0.0
ALA B:318 B:256 24.0 0.209 H -61.5 -52.2 NA NA NA
3zkm 1 Q9Y5Z0 100.0 0.0 X-RAY
 2013-05-29 ALA A:244 A:256 21.0 0.183 H -61.7 -39.3 21.0 0.183 0.0 HOH
 2.552
 O
 O
ALA B:244 B:256 21.0 0.183 H -62.0 -40.4 NA NA NA
3zkn 1 Q9Y5Z0 100.0 0.0 X-RAY
 2013-05-29 ALA A:244 A:256 23.0 0.2 H -66.4 -38.2 NA NA NA
ALA B:244 B:256 21.0 0.183 H -56.5 -41.5 21.0 0.183 0.0 HOH
 2.643
 O
 O
3zkq 1 Q9Y5Z0 100.0 0.0 X-RAY
 2013-05-29 ALA A:244 A:256 21.0 0.183 H -62.5 -39.9 21.0 0.183 0.0 HOH
 2.750
 O
 O
3zks 1 Q9Y5Z0 100.0 0.0 X-RAY
 2013-05-29 ALA A:244 A:256 17.0 0.148 H -57.5 -40.4 17.0 0.148 0.0 HOH
 2.496
 O
 O
4bel 1 Q9Y5Z0 100.0 0.0 X-RAY
 2013-05-29 ALA A:244 A:256 22.0 0.191 H -65.1 -43.2 22.0 0.191 0.0 HOH
 2.665
 O
 O
ALA B:244 B:256 25.0 0.217 H -59.3 -40.9 NA NA NA
4bfb 1 Q9Y5Z0 100.0 0.0 X-RAY
 2013-05-29 ALA A:244 A:256 31.0 0.27 H -64.8 -35.2 31.0 0.27 0.0 HOH
 3.586
 N
 O
ALA B:244 B:256 26.0 0.226 H -55.4 -40.3 NA NA NA
6jsz 1 Q9Y5Z0 100.0 0.0 X-RAY
 2019-08-28 ALA A:244 A:256 25.0 0.217 H -66.4 -42.5 25.0 0.217 0.0 HOH
 2.996
 O
 O
7d5b 1 Q9Y5Z0 100.0 0.0 X-RAY
 2021-03-31 ALA A:244 A:256 16.0 0.139 H -64.6 -41.1 16.0 0.139 0.0 HOH
 2.712
 O
 O
7d5u 1 Q9Y5Z0 100.0 0.0 X-RAY
 2021-03-31 ALA A:244 A:256 27.0 0.235 H -64.5 -32.1 27.0 0.235 0.0 HOH
 3.671
 N
 O
7n4n 1 Q9Y5Z0 100.0 0.0 X-RAY
 2021-10-06 ALA A:244 A:256 18.0 0.157 H -68.7 -41.2 18.0 0.157 0.0 HOH
 2.659
 O
 O
3zkg 1 Q9Y5Z0 99.74 0.0 X-RAY
 2013-05-29 ALA A:244 A:256 30.0 0.261 H -66.3 -41.5 30.0 0.261 0.0 HOH
 2.865
 O
 O
ALA B:244 B:256 22.0 0.191 H -56.6 -42.7 NA NA NA
3zki 1 Q9Y5Z0 99.74 0.0 X-RAY
 2013-05-29 ALA A:244 A:256 28.0 0.243 H -70.4 -35.4 28.0 0.243 0.0 HOH
 2.740
 O
 O
ALA B:244 B:256 10.0 0.087 H -66.3 -40.4 NA NA NA
3zkx 1 Q9Y5Z0 99.74 0.0 X-RAY
 2013-05-29 ALA A:244 A:256 21.0 0.183 H -63.8 -41.3 21.0 0.183 0.0 HOH
 2.770
 O
 O
3zl7 1 Q9Y5Z0 99.74 0.0 X-RAY
 2013-05-29 ALA A:244 A:256 31.0 0.27 H -66.8 -33.6 31.0 0.27 0.0
3zlq 1 Q9Y5Z0 99.74 0.0 X-RAY
 2013-05-01 ALA A:244 A:256 27.0 0.235 H -55.1 -49.2 27.0 0.235 0.0 HOH
 9.208
 CB
 O
ALA B:244 B:256 18.0 0.157 H -78.4 -26.9 18.0 0.157 0.0
2ewy 1 Q9Y5Z0 100.0 0.0 X-RAY
 2006-11-07 ALA A:241 A:256 18.0 0.157 H -48.7 -48.7 18.0 0.157 0.0 HOH
 7.255
 N
 O
ALA B:241 B:256 20.0 0.174 H -48.7 -48.7 NA NA NA
ALA C:241 C:256 20.0 0.174 H -48.6 -48.7 NA NA NA
ALA D:241 D:256 19.0 0.165 H -48.6 -48.8 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q9y5z0-f1 1 Q9Y5Z0 100.0 0.0 ALA A:318 A:318 21.0 0.183 H -65.0 -38.4