Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr21 | 42629199 | . | G | A | CCDS13668.1:NM_012105.4:c.1249Gtc>Atc_NP_036237.2:p.417V>I | Homo sapiens beta-site APP-cleaving enzyme 2 (BACE2), transcript variant a, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 6uj0 | 1 | Q9Y5Z0 | 99.78 | 0.0 |
X-RAY |
2020-10-07 | VAL | A:417 | A:355 | 1.0 | 0.006 | E | -106.8 | 133.5 | 1.0 | 0.006 | 0.0 |
HOH |
3.994 |
CG2 |
O |
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| VAL | B:417 | B:355 | 0.0 | 0.0 | E | -116.5 | 126.7 | NA | NA | NA | |||||||||||||
| 6uj1 | 1 | Q9Y5Z0 | 99.78 | 0.0 |
X-RAY |
2020-10-07 | VAL | A:417 | A:355 | 1.0 | 0.006 | E | -107.8 | 128.9 | 1.0 | 0.006 | 0.0 | ||||||
| VAL | B:417 | B:355 | 0.0 | 0.0 | E | -118.3 | 124.5 | NA | NA | NA | |||||||||||||
| 3zkm | 1 | Q9Y5Z0 | 100.0 | 0.0 |
X-RAY |
2013-05-29 | VAL | A:343 | A:355 | 0.0 | 0.0 | E | -113.6 | 126.4 | 0.0 | 0.0 | 0.0 |
HOH |
3.760 |
CG2 |
O |
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| VAL | B:343 | B:355 | 0.0 | 0.0 | E | -107.1 | 128.8 | NA | NA | NA | |||||||||||||
| 3zkn | 1 | Q9Y5Z0 | 100.0 | 0.0 |
X-RAY |
2013-05-29 | VAL | A:343 | A:355 | 0.0 | 0.0 | E | -111.9 | 129.2 | NA | NA | NA | ||||||
| VAL | B:343 | B:355 | 0.0 | 0.0 | E | -116.0 | 122.3 | 0.0 | 0.0 | 0.0 |
HOH |
3.878 |
CG2 |
O |
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| 3zkq | 1 | Q9Y5Z0 | 100.0 | 0.0 |
X-RAY |
2013-05-29 | VAL | A:343 | A:355 | 0.0 | 0.0 | E | -112.7 | 125.2 | 0.0 | 0.0 | 0.0 |
HOH |
4.002 |
CG2 |
O |
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| 3zks | 1 | Q9Y5Z0 | 100.0 | 0.0 |
X-RAY |
2013-05-29 | VAL | A:343 | A:355 | 1.0 | 0.006 | E | -105.5 | 126.9 | 1.0 | 0.006 | 0.0 |
HOH |
4.028 |
CG2 |
O |
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| 4bel | 1 | Q9Y5Z0 | 100.0 | 0.0 |
X-RAY |
2013-05-29 | VAL | A:343 | A:355 | 0.0 | 0.0 | E | -113.9 | 124.2 | 0.0 | 0.0 | 0.0 |
HOH |
4.081 |
CG2 |
O |
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| VAL | B:343 | B:355 | 0.0 | 0.0 | E | -111.1 | 123.8 | NA | NA | NA | |||||||||||||
| 4bfb | 1 | Q9Y5Z0 | 100.0 | 0.0 |
X-RAY |
2013-05-29 | VAL | A:343 | A:355 | 1.0 | 0.006 | E | -113.9 | 125.8 | 1.0 | 0.006 | 0.0 |
HOH |
4.371 |
CG2 |
O |
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| VAL | B:343 | B:355 | 0.0 | 0.0 | E | -118.2 | 129.4 | NA | NA | NA | |||||||||||||
| 6jsz | 1 | Q9Y5Z0 | 100.0 | 0.0 |
X-RAY |
2019-08-28 | VAL | A:343 | A:355 | 0.0 | 0.0 | E | -108.4 | 123.0 | 0.0 | 0.0 | 0.0 |
HOH |
3.935 |
CG2 |
O |
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| 7d5b | 1 | Q9Y5Z0 | 100.0 | 0.0 |
X-RAY |
2021-03-31 | VAL | A:343 | A:355 | 0.0 | 0.0 | E | -113.6 | 126.6 | 0.0 | 0.0 | 0.0 |
HOH |
4.023 |
CG2 |
O |
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| 7d5u | 1 | Q9Y5Z0 | 100.0 | 0.0 |
X-RAY |
2021-03-31 | VAL | A:343 | A:355 | 0.0 | 0.0 | E | -107.0 | 127.5 | 0.0 | 0.0 | 0.0 |
HOH |
3.879 |
CG2 |
O |
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| 7n4n | 1 | Q9Y5Z0 | 100.0 | 0.0 |
X-RAY |
2021-10-06 | VAL | A:343 | A:355 | 0.0 | 0.0 | E | -114.4 | 124.2 | 0.0 | 0.0 | 0.0 |
HOH |
3.340 |
HG23 |
O |
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| 3zkg | 1 | Q9Y5Z0 | 99.74 | 0.0 |
X-RAY |
2013-05-29 | VAL | A:343 | A:355 | 0.0 | 0.0 | E | -118.2 | 123.3 | 0.0 | 0.0 | 0.0 |
HOH |
4.113 |
CG2 |
O |
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| VAL | B:343 | B:355 | 0.0 | 0.0 | E | -115.2 | 131.2 | NA | NA | NA | |||||||||||||
| 3zki | 1 | Q9Y5Z0 | 99.74 | 0.0 |
X-RAY |
2013-05-29 | VAL | A:343 | A:355 | 0.0 | 0.0 | E | -120.5 | 129.7 | 0.0 | 0.0 | 0.0 |
HOH |
3.925 |
CG2 |
O |
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| VAL | B:343 | B:355 | 0.0 | 0.0 | E | -118.5 | 130.1 | NA | NA | NA | |||||||||||||
| 3zkx | 1 | Q9Y5Z0 | 99.74 | 0.0 |
X-RAY |
2013-05-29 | VAL | A:343 | A:355 | 0.0 | 0.0 | E | -107.4 | 124.9 | 0.0 | 0.0 | 0.0 |
HOH |
3.907 |
CG2 |
O |
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| 3zl7 | 1 | Q9Y5Z0 | 99.74 | 0.0 |
X-RAY |
2013-05-29 | VAL | A:343 | A:355 | 1.0 | 0.006 | E | -84.8 | 126.1 | 1.0 | 0.006 | 0.0 | ||||||
| 3zlq | 1 | Q9Y5Z0 | 99.74 | 0.0 |
X-RAY |
2013-05-01 | VAL | A:343 | A:355 | 1.0 | 0.006 | E | -119.4 | 120.7 | 1.0 | 0.006 | 0.0 |
HOH |
5.774 |
N |
O |
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| VAL | B:343 | B:355 | 0.0 | 0.0 | E | -127.9 | 125.4 | 0.0 | 0.0 | 0.0 |
HOH |
4.981 |
O |
O |
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| 2ewy | 1 | Q9Y5Z0 | 100.0 | 0.0 |
X-RAY |
2006-11-07 | VAL | A:340 | A:355 | 1.0 | 0.006 | E | -95.5 | 130.2 | 1.0 | 0.006 | 0.0 |
HOH |
9.469 |
CG1 |
O |
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| VAL | B:340 | B:355 | 0.0 | 0.0 | E | -95.5 | 130.2 | NA | NA | NA | |||||||||||||
| VAL | C:340 | C:355 | 0.0 | 0.0 | E | -95.5 | 130.2 | NA | NA | NA | |||||||||||||
| VAL | D:340 | D:355 | 1.0 | 0.006 | E | -95.5 | 130.2 | NA | NA | NA | |||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-q9y5z0-f1 | 1 | Q9Y5Z0 | 100.0 | 0.0 | VAL | A:417 | A:417 | 1.0 | 0.006 | E | -110.4 | 126.0 | |