Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr22 30032747 . G A CCDS13861.1:NM_000268.3:c.122tGg>tAg_NP_000259.1:p.41W>* Homo sapiens neurofibromin 2 (NF2), transcript variant 1, mRNA.
pdb_id: 
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label_seq_id: 
label_comp_id: 
auth_asym_id: 
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6cds 1 P35240 99.71 0.0 X-RAY
 2018-07-18 TRP A:41 A:41 35.0 0.137 -54.2 141.7 35.0 0.137 0.0 HOH
 4.643
 CZ2
 O
TRP B:41 B:41 34.0 0.133 -53.6 141.8 NA NA NA
7lwh 1 P35240 99.41 0.0 X-RAY
 2021-08-11 TRP A:41 A:41 43.0 0.169 -96.3 139.7 43.0 0.169 0.0
1isn 1 P46662 99.38 0.0 X-RAY
 2002-04-03 TRP A:24 A:41 55.0 0.216 -76.6 146.5 55.0 0.216 0.0
4zrj 1 P35240 100.0 0.0 X-RAY
 2015-06-17 TRP A:41 A:41 62.0 0.243 -69.7 143.7 62.0 0.243 0.0 HOH
 2.887
 O
 O
4zri 1 P35240 100.0 0.0 X-RAY
 2015-06-17 TRP A:45 A:41 62.0 0.243 -59.3 139.4 62.0 0.243 0.0
TRP B:45 B:41 14.0 NA -58.9 148.6 NA NA NA
4zrk 1 P46662 99.38 0.0 X-RAY
 2015-06-17 TRP A:45 A:41 49.0 0.192 -63.6 130.8 49.0 0.192 0.0
TRP B:45 B:41 47.0 0.184 -60.5 133.4 NA NA NA
TRP C:45 C:41 49.0 0.192 -61.7 133.3 NA NA NA
TRP D:45 D:41 50.0 0.196 -62.5 133.5 NA NA NA
1h4r 1 P35240 100.0 0.0 X-RAY
 2002-01-16 TRP A:42 A:41 53.0 0.208 -63.1 148.5 53.0 0.208 0.0 SO4
HOH
 7.961
3.004
 N
NE1
 O4
O
TRP B:42 B:41 55.0 0.216 -59.1 153.8 55.0 0.216 0.0 SO4
HOH
 7.607
3.451
 N
NE1
 O2
O
4p7i 1 P46662 99.36 0.0 X-RAY
 2014-04-09 TRP A:45 A:41 54.0 0.212 -69.6 138.6 54.0 0.212 0.0 GOL
HOH
 8.172
4.851
 CH2
CZ2
 O3
O
TRP B:45 B:41 59.0 0.231 -69.0 143.0 NA NA NA
3u8z 1 P35240 100.0 0.0 X-RAY
 2011-11-02 TRP A:29 A:41 52.0 0.204 -68.3 141.0 12.0 0.047 0.157 C:P35240:0.157
 HOH
 2.621
 O
 O
TRP B:29 B:41 52.0 0.204 -68.1 140.1 NA NA NA
TRP C:29 C:41 55.0 0.216 -68.5 140.5 55.0 0.216 0.0 HOH
 6.490
 NE1
 O
TRP D:29 D:41 56.0 0.22 -68.3 140.2 NA NA NA
3wa0 1 P46662 99.32 0.0 X-RAY
 2014-05-28 TRP A:28 A:41 67.0 0.263 -64.0 157.5 67.0 0.263 0.0
TRP B:28 B:41 70.0 0.275 -63.4 158.8 NA NA NA
TRP C:28 C:41 70.0 0.275 -62.0 153.4 NA NA NA
TRP D:28 D:41 58.0 0.227 -66.9 152.7 NA NA NA
TRP E:28 E:41 65.0 0.255 -58.9 135.0 NA NA NA
TRP F:28 F:41 86.0 0.337 -55.6 126.1 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p35240-f1 1 P35240 100.0 0.0 TRP A:41 A:41 44.0 0.173 -62.7 138.1