Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr22 30051658 . C A CCDS13861.1:NM_000268.3:c.592Cga>Aga_NP_000259.1:p.198R>R Homo sapiens neurofibromin 2 (NF2), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6cds 1 P35240 99.71 0.0 X-RAY
 2018-07-18 ARG A:198 A:198 82.0 0.364 -76.4 130.5 82.0 0.364 0.0 HOH
 3.529
 CD
 O
ARG B:198 B:198 78.0 0.347 -76.2 131.1 NA NA NA
7lwh 1 P35240 99.41 0.0 X-RAY
 2021-08-11 ARG A:198 A:198 106.0 0.471 -85.8 118.3 106.0 0.471 0.0 HOH
 2.824
 O
 O
1isn 1 P46662 99.38 0.0 X-RAY
 2002-04-03 ARG A:181 A:198 97.0 0.431 -87.8 131.4 97.0 0.431 0.0
4zrj 1 P35240 100.0 0.0 X-RAY
 2015-06-17 ARG A:198 A:198 79.0 0.351 -89.2 122.8 79.0 0.351 0.0 HOH
 3.639
 O
 O
4zri 1 P35240 100.0 0.0 X-RAY
 2015-06-17 ARG A:202 A:198 84.0 0.373 -87.9 114.1 84.0 0.373 0.0
ARG B:202 B:198 88.0 0.391 -65.6 118.2 NA NA NA
4zrk 1 P46662 99.38 0.0 X-RAY
 2015-06-17 ARG A:202 A:198 89.0 0.396 -83.2 121.7 63.0 0.28 0.116 E:O95835:0.116
ARG B:202 B:198 74.0 0.329 -82.5 118.7 NA NA NA
ARG C:202 C:198 89.0 0.396 -80.4 118.1 NA NA NA
ARG D:202 D:198 81.0 0.36 -81.0 122.1 NA NA NA
1h4r 1 P35240 100.0 0.0 X-RAY
 2002-01-16 ARG A:199 A:198 104.0 0.462 -79.0 125.3 104.0 0.462 0.0 SO4
HOH
 2.860
2.513
 NH2
NH1
 O4
O
ARG B:199 B:198 95.0 0.422 -91.2 127.1 95.0 0.422 0.0 SO4
HOH
 2.506
3.331
 CD
NH2
 O4
O
4p7i 1 P46662 99.36 0.0 X-RAY
 2014-04-09 ARG A:202 A:198 83.0 0.369 -92.0 122.2 83.0 0.369 0.0
ARG B:202 B:198 83.0 0.369 -103.2 138.2 NA NA NA
3u8z 1 P35240 100.0 0.0 X-RAY
 2011-11-02 ARG A:186 A:198 184.0 0.818 -72.3 132.0 29.0 0.129 0.689 C:P35240:0.689
 HOH
 2.790
 O
 O
ARG B:186 B:198 180.0 0.8 -73.0 132.5 NA NA NA
ARG C:186 C:198 134.0 0.596 -74.8 131.0 7.0 0.031 0.565 A:P35240:0.564
 HOH
 2.783
 O
 O
ARG D:186 NA:NA DO NA DO DO DO NA NA NA
3wa0 1 P46662 99.32 0.0 X-RAY
 2014-05-28 ARG A:185 A:198 94.0 0.418 -93.4 129.1 94.0 0.418 0.0 HOH
 3.475
 NH1
 O
ARG B:185 B:198 90.0 0.4 -86.2 119.2 NA NA NA
ARG C:185 C:198 84.0 0.373 -90.3 122.3 NA NA NA
ARG D:185 D:198 91.0 0.404 -87.0 126.5 NA NA NA
ARG E:185 E:198 92.0 0.409 -89.4 122.7 NA NA NA
ARG F:185 F:198 89.0 0.396 -90.9 124.3 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p35240-f1 1 P35240 100.0 0.0 ARG A:198 A:198 86.0 0.382 -102.2 128.7