Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr22 41648953 . A C CCDS14012.1:NM_001278651.1:c.1303Tcc>Gcc_NP_001265580.1:p.435S>A Homo sapiens Ran GTPase activating protein 1 (RANGAP1), transcript variant 1, mRNA.
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5d2m 3 P46060 100.0 6e-119 X-RAY
 2015-11-04 SER C:19 C:435 58.0 0.504 H -56.7 -34.4 58.0 0.504 0.0 HOH
 2.930
 O
 O
SER F:19 F:435 47.0 0.409 H -70.5 -35.2 NA NA NA
1z5s 3 P46060 100.0 7e-119 X-RAY
 2005-06-07 SER C:20 C:435 61.0 0.53 H -46.1 -69.7 61.0 0.53 0.0
2grn 2 P46060 99.41 4e-118 X-RAY
 2006-05-30 SER B:18 B:435 88.0 0.765 H -58.7 -45.4 88.0 0.765 0.0 HOH
 3.610
 OG
 O
2gro 2 P46060 99.41 4e-118 X-RAY
 2006-05-30 SER B:18 B:435 90.0 0.783 H -61.5 -41.5 90.0 0.783 0.0 HOH
 2.846
 O
 O
2grp 2 P46060 99.41 4e-118 X-RAY
 2006-05-30 SER B:18 B:435 92.0 0.8 H -60.9 -39.3 92.0 0.8 0.0 HOH
 2.690
 O
 O
2grq 2 P46060 99.41 4e-118 X-RAY
 2006-05-30 SER B:18 B:435 90.0 0.783 H -60.5 -44.5 90.0 0.783 0.0 HOH
 2.862
 O
 O
2grr 2 P46060 99.41 4e-118 X-RAY
 2006-05-30 SER B:18 B:435 85.0 0.739 H -61.6 -45.7 85.0 0.739 0.0 HOH
 2.827
 O
 O
3uin 3 P46060 100.0 5e-118 X-RAY
 2011-12-28 SER C:19 C:435 68.0 0.591 H -52.3 -49.6 68.0 0.591 0.0
3uio 3 P46060 100.0 5e-118 X-RAY
 2011-12-28 SER C:19 C:435 53.0 0.461 H -60.0 -28.8 53.0 0.461 0.0
3uip 3 P46060 100.0 5e-118 X-RAY
 2011-12-28 SER C:19 C:435 65.0 0.565 H -58.8 -41.5 65.0 0.565 0.0 HOH
 6.190
 C
 O
2io2 3 P46060 99.41 1e-117 X-RAY
 2006-11-21 SER C:20 C:435 83.0 0.722 H -52.9 -39.2 37.0 0.322 0.4 B:P63165:0.4
 HOH
 8.502
 CB
 O
2io3 3 P46060 99.41 1e-117 X-RAY
 2006-11-14 SER C:20 C:435 64.0 0.557 H -67.7 -33.6 31.0 0.27 0.287 B:P61956:0.287
2iy0 3 P46060 100.0 2e-107 X-RAY
 2006-08-07 SER C:4 C:435 55.0 0.478 H -61.0 -44.8 55.0 0.478 0.0
1kps 2 P46061 81.76 3e-98 X-RAY
 2002-02-13 SER B:19 B:437 60.0 0.522 H -75.8 -23.9 60.0 0.522 0.0 HOH
 3.234
 N
 O
SER D:19 D:437 69.0 0.6 H -68.8 -26.6 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p46060-f1 1 P46060 100.0 0.0 SER A:435 A:435 66.0 0.574 H -57.4 -44.5