Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr3 | 10183795 | . | G | A | CCDS2597.1:NM_000551.3:c.264tgG>tgA_NP_000542.1:p.88W>* | Homo sapiens von Hippel-Lindau tumor suppressor (VHL), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 4wqo | 1 | P40337 | 100.0 | 4e-156 |
X-RAY |
2015-03-04 | TRP | A:108 | A:88 | 36.0 | 0.141 | E | -98.3 | 132.6 | 36.0 | 0.141 | 0.0 | ||||||
| 7q2j | 3 | P40337 | 94.25 | 1e-118 |
X-RAY |
2021-11-24 | TRP | C:72 | C:88 | 35.0 | 0.137 | E | -103.6 | 131.5 | 35.0 | 0.137 | 0.0 |
8KH |
3.405 |
CE2 |
C32 |
||
| 4b9k | 3 | P40337 | 95.32 | 3e-118 |
X-RAY |
2012-10-24 | TRP | C:46 | C:88 | 30.0 | 0.118 | E | -94.6 | 131.6 | 30.0 | 0.118 | 0.0 |
TG0 HOH |
3.526 4.051 |
CE2 CZ3 |
C28 O |
||
| TRP | F:46 | F:88 | 30.0 | 0.118 | E | -95.1 | 131.8 | NA | NA | NA | |||||||||||||
| TRP | I:46 | I:88 | 29.0 | 0.114 | E | -95.9 | 132.3 | NA | NA | NA | |||||||||||||
| TRP | L:46 | L:88 | 29.0 | 0.114 | E | -95.4 | 132.5 | NA | NA | NA | |||||||||||||
| 1lqb | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2002-07-03 | TRP | C:37 | C:88 | 20.0 | 0.078 | E | -103.7 | 129.0 | 5.0 | 0.02 | 0.058 |
D:Q16665:0.059 |
HOH |
6.502 |
CZ2 |
O |
|
| 3ztd | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2012-07-25 | TRP | C:37 | C:88 | 9.0 | 0.035 | E | -100.9 | 132.7 | 9.0 | 0.035 | 0.0 |
ZTD HOH |
3.333 6.410 |
CE2 CZ2 |
CD2 O |
||
| TRP | F:37 | F:88 | 10.0 | 0.039 | E | -73.7 | 136.4 | NA | NA | NA | |||||||||||||
| TRP | I:37 | I:88 | 10.0 | 0.039 | E | -88.3 | 140.2 | NA | NA | NA | |||||||||||||
| TRP | L:37 | L:88 | 13.0 | 0.051 | E | -93.6 | 134.3 | NA | NA | NA | |||||||||||||
| 4b95 | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2012-10-24 | TRP | C:37 | C:88 | 25.0 | 0.098 | E | -94.4 | 130.2 | 25.0 | 0.098 | 0.0 |
UCK HOH |
3.536 6.631 |
CH2 CZ2 |
C21 O |
||
| TRP | F:37 | F:88 | 32.0 | 0.125 | E | -95.1 | 130.3 | NA | NA | NA | |||||||||||||
| TRP | I:37 | I:88 | 33.0 | 0.129 | E | -95.3 | 131.8 | NA | NA | NA | |||||||||||||
| TRP | L:37 | L:88 | 26.0 | 0.102 | E | -94.9 | 131.4 | NA | NA | NA | |||||||||||||
| 4bks | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2013-11-27 | TRP | C:37 | C:88 | 9.0 | 0.035 | E | -96.4 | 135.3 | 9.0 | 0.035 | 0.0 |
X6C HOH |
3.511 4.362 |
CE2 CZ3 |
CD2 O |
||
| TRP | F:37 | F:88 | 10.0 | 0.039 | E | -96.6 | 135.6 | NA | NA | NA | |||||||||||||
| TRP | I:37 | I:88 | 10.0 | 0.039 | E | -95.8 | 135.0 | NA | NA | NA | |||||||||||||
| TRP | L:37 | L:88 | 11.0 | 0.043 | E | -94.9 | 135.2 | NA | NA | NA | |||||||||||||
| 4bkt | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2013-11-27 | TRP | C:37 | C:88 | 25.0 | 0.098 | E | -96.5 | 132.3 | 25.0 | 0.098 | 0.0 |
QD0 HOH |
3.472 4.372 |
CE2 CH2 |
C17 O |
||
| TRP | F:37 | F:88 | 26.0 | 0.102 | E | -97.1 | 132.9 | NA | NA | NA | |||||||||||||
| TRP | I:37 | I:88 | 27.0 | 0.106 | E | -96.5 | 132.6 | NA | NA | NA | |||||||||||||
| TRP | L:37 | L:88 | 25.0 | 0.098 | E | -94.2 | 127.9 | NA | NA | NA | |||||||||||||
| 4w9c | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2014-09-10 | TRP | C:37 | C:88 | 4.0 | 0.016 | E | -93.7 | 128.6 | 4.0 | 0.016 | 0.0 |
3JG HOH |
3.520 3.847 |
CE2 CH2 |
CD2 O |
||
| TRP | F:37 | F:88 | 3.0 | 0.012 | E | -98.8 | 130.4 | NA | NA | NA | |||||||||||||
| TRP | I:37 | I:88 | 3.0 | 0.012 | E | -95.1 | 131.9 | NA | NA | NA | |||||||||||||
| TRP | L:37 | L:88 | 4.0 | 0.016 | E | -92.4 | 128.9 | NA | NA | NA | |||||||||||||
| 4w9d | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2014-09-10 | TRP | C:37 | C:88 | 4.0 | 0.016 | E | -94.4 | 131.9 | 4.0 | 0.016 | 0.0 |
3JK HOH |
3.555 4.673 |
CE2 CH2 |
CD2 O |
||
| TRP | F:37 | F:88 | 4.0 | 0.016 | E | -96.6 | 133.3 | NA | NA | NA | |||||||||||||
| TRP | I:37 | I:88 | 4.0 | 0.016 | E | -93.4 | 133.2 | NA | NA | NA | |||||||||||||
| TRP | L:37 | L:88 | 4.0 | 0.016 | E | -92.3 | 128.9 | NA | NA | NA | |||||||||||||
| 4w9e | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2014-09-10 | TRP | C:37 | C:88 | 3.0 | 0.012 | E | -93.5 | 123.9 | 3.0 | 0.012 | 0.0 |
3JT HOH |
3.612 4.114 |
CE2 CH2 |
CD2 O |
||
| TRP | F:37 | F:88 | 4.0 | 0.016 | E | -96.0 | 129.8 | NA | NA | NA | |||||||||||||
| TRP | I:37 | I:88 | 4.0 | 0.016 | E | -92.1 | 130.2 | NA | NA | NA | |||||||||||||
| TRP | L:37 | L:88 | 4.0 | 0.016 | E | -91.6 | 129.1 | NA | NA | NA | |||||||||||||
| 4w9f | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2014-09-10 | TRP | C:37 | C:88 | 3.0 | 0.012 | E | -96.5 | 132.7 | 3.0 | 0.012 | 0.0 |
3JU HOH |
3.454 4.147 |
CE2 CZ3 |
CD2 O |
||
| TRP | F:37 | F:88 | 3.0 | 0.012 | E | -94.8 | 130.4 | NA | NA | NA | |||||||||||||
| TRP | I:37 | I:88 | 11.0 | 0.043 | E | -99.2 | 129.1 | NA | NA | NA | |||||||||||||
| TRP | L:37 | L:88 | 3.0 | 0.012 | E | -93.5 | 130.4 | NA | NA | NA | |||||||||||||
| 4w9g | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2014-09-10 | TRP | C:37 | C:88 | 3.0 | 0.012 | E | -97.5 | 122.0 | 3.0 | 0.012 | 0.0 |
3JV HOH |
3.616 4.869 |
CE2 CH2 |
CD2 O |
||
| TRP | F:37 | F:88 | 3.0 | 0.012 | E | -100.2 | 129.7 | NA | NA | NA | |||||||||||||
| TRP | I:37 | I:88 | 4.0 | 0.016 | E | -92.4 | 130.0 | NA | NA | NA | |||||||||||||
| TRP | L:37 | L:88 | 3.0 | 0.012 | E | -87.5 | 132.1 | NA | NA | NA | |||||||||||||
| 4w9h | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2014-09-10 | TRP | C:37 | C:88 | 4.0 | 0.016 | E | -94.0 | 130.4 | 4.0 | 0.016 | 0.0 |
3JF HOH |
3.496 4.343 |
CE2 CZ3 |
CD2 O |
||
| TRP | F:37 | F:88 | 3.0 | 0.012 | E | -98.5 | 132.4 | NA | NA | NA | |||||||||||||
| TRP | I:37 | I:88 | 5.0 | 0.02 | E | -95.5 | 131.0 | NA | NA | NA | |||||||||||||
| TRP | L:37 | L:88 | 4.0 | 0.016 | E | -92.7 | 131.0 | NA | NA | NA | |||||||||||||
| 4w9i | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2014-09-10 | TRP | C:37 | C:88 | 5.0 | 0.02 | E | -94.1 | 128.2 | 5.0 | 0.02 | 0.0 |
3JS HOH |
3.482 4.109 |
CE2 CZ3 |
CD2 O |
||
| TRP | F:37 | F:88 | 1.0 | 0.004 | E | -98.9 | 130.1 | NA | NA | NA | |||||||||||||
| TRP | I:37 | I:88 | 1.0 | 0.004 | E | -93.6 | 127.4 | NA | NA | NA | |||||||||||||
| TRP | L:37 | L:88 | 1.0 | 0.004 | E | -91.4 | 127.1 | NA | NA | NA | |||||||||||||
| 4w9j | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2014-09-10 | TRP | C:37 | C:88 | 2.0 | 0.008 | E | -100.2 | 131.6 | 2.0 | 0.008 | 0.0 |
3JH HOH |
3.603 4.270 |
CE2 CH2 |
CAW O |
||
| TRP | F:37 | F:88 | 3.0 | 0.012 | E | -93.7 | 133.4 | NA | NA | NA | |||||||||||||
| TRP | I:37 | I:88 | 3.0 | 0.012 | E | -98.2 | 132.1 | NA | NA | NA | |||||||||||||
| TRP | L:37 | L:88 | 3.0 | 0.012 | E | -98.3 | 131.7 | NA | NA | NA | |||||||||||||
| 4w9k | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2014-09-10 | TRP | C:37 | C:88 | 3.0 | 0.012 | E | -94.4 | 130.5 | 3.0 | 0.012 | 0.0 |
3JO HOH |
3.553 4.503 |
CE2 CH2 |
CAX O |
||
| TRP | F:37 | F:88 | 4.0 | 0.016 | E | -96.0 | 132.0 | NA | NA | NA | |||||||||||||
| TRP | I:37 | I:88 | 4.0 | 0.016 | E | -99.6 | 131.6 | NA | NA | NA | |||||||||||||
| TRP | L:37 | L:88 | 4.0 | 0.016 | E | -92.8 | 128.9 | NA | NA | NA | |||||||||||||
| 4w9l | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2014-09-10 | TRP | C:37 | C:88 | 3.0 | 0.012 | E | -98.6 | 130.3 | 3.0 | 0.012 | 0.0 |
3JJ HOH |
3.600 4.697 |
CE2 CH2 |
CAU O |
||
| TRP | F:37 | F:88 | 3.0 | 0.012 | E | -101.1 | 131.3 | NA | NA | NA | |||||||||||||
| TRP | I:37 | I:88 | 2.0 | 0.008 | E | -101.5 | 130.2 | NA | NA | NA | |||||||||||||
| TRP | L:37 | L:88 | 3.0 | 0.012 | E | -94.0 | 128.1 | NA | NA | NA | |||||||||||||
| 5lli | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2016-11-09 | TRP | C:37 | C:88 | 3.0 | 0.012 | E | -96.9 | 134.9 | 3.0 | 0.012 | 0.0 |
6Z3 HOH |
3.605 4.570 |
CE2 CZ3 |
CD2 O |
||
| TRP | F:37 | F:88 | 4.0 | 0.016 | E | -95.8 | 133.7 | NA | NA | NA | |||||||||||||
| TRP | I:37 | I:88 | 4.0 | 0.016 | E | -97.7 | 130.3 | NA | NA | NA | |||||||||||||
| TRP | L:37 | L:88 | 3.0 | 0.012 | E | -95.0 | 127.7 | NA | NA | NA | |||||||||||||
| 5nvv | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2017-09-20 | TRP | C:37 | C:88 | 3.0 | 0.012 | E | -93.4 | 131.7 | 3.0 | 0.012 | 0.0 |
9BT HOH |
3.484 4.257 |
CE2 CZ3 |
CD2 O |
||
| TRP | F:37 | F:88 | 4.0 | 0.016 | E | -93.6 | 131.2 | NA | NA | NA | |||||||||||||
| TRP | I:37 | I:88 | 4.0 | 0.016 | E | -97.7 | 128.9 | NA | NA | NA | |||||||||||||
| TRP | L:37 | L:88 | 3.0 | 0.012 | E | -92.1 | 128.0 | NA | NA | NA | |||||||||||||
| 5nvw | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2017-09-20 | TRP | C:37 | C:88 | 4.0 | 0.016 | E | -93.5 | 132.7 | 4.0 | 0.016 | 0.0 |
9BW HOH |
3.510 4.202 |
CE2 CZ3 |
CD2 O |
||
| TRP | F:37 | F:88 | 3.0 | 0.012 | E | -97.1 | 129.7 | NA | NA | NA | |||||||||||||
| TRP | I:37 | I:88 | 4.0 | 0.016 | E | -95.6 | 130.0 | NA | NA | NA | |||||||||||||
| TRP | L:37 | L:88 | 2.0 | 0.008 | E | -89.8 | 130.1 | NA | NA | NA | |||||||||||||
| 5nvx | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2017-09-20 | TRP | C:37 | C:88 | 4.0 | 0.016 | E | -94.1 | 131.3 | 4.0 | 0.016 | 0.0 |
4YY HOH |
3.509 4.300 |
CE2 CZ3 |
CD2 O |
||
| TRP | F:37 | F:88 | 4.0 | 0.016 | E | -95.9 | 130.5 | NA | NA | NA | |||||||||||||
| TRP | I:37 | I:88 | 4.0 | 0.016 | E | -95.6 | 127.9 | NA | NA | NA | |||||||||||||
| TRP | L:37 | L:88 | 3.0 | 0.012 | E | -93.0 | 129.2 | NA | NA | NA | |||||||||||||
| 5nvy | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2017-09-20 | TRP | C:37 | C:88 | 4.0 | 0.016 | E | -85.5 | 132.1 | 4.0 | 0.016 | 0.0 |
9B5 HOH |
3.488 4.416 |
CE2 CH2 |
CAO O |
||
| TRP | F:37 | F:88 | 4.0 | 0.016 | E | -93.1 | 134.3 | NA | NA | NA | |||||||||||||
| TRP | I:37 | I:88 | 4.0 | 0.016 | E | -92.9 | 133.3 | NA | NA | NA | |||||||||||||
| TRP | L:37 | L:88 | 5.0 | 0.02 | E | -95.2 | 123.1 | NA | NA | NA | |||||||||||||
| 5nvz | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2017-09-20 | TRP | C:37 | C:88 | 4.0 | 0.016 | E | -95.0 | 131.0 | 4.0 | 0.016 | 0.0 |
9BN HOH |
3.640 4.577 |
CE2 CZ3 |
CD2 O |
||
| TRP | F:37 | F:88 | 4.0 | 0.016 | E | -104.5 | 131.6 | NA | NA | NA | |||||||||||||
| TRP | I:37 | I:88 | 4.0 | 0.016 | E | -90.3 | 137.7 | NA | NA | NA | |||||||||||||
| TRP | L:37 | L:88 | 4.0 | 0.016 | E | -90.3 | 133.8 | NA | NA | NA | |||||||||||||
| 5nw0 | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2017-09-20 | TRP | C:37 | C:88 | 4.0 | 0.016 | E | -97.7 | 132.7 | 4.0 | 0.016 | 0.0 |
9BK HOH |
3.616 4.305 |
CE2 CZ3 |
CD2 O |
||
| TRP | F:37 | F:88 | 5.0 | 0.02 | E | -100.0 | 128.6 | NA | NA | NA | |||||||||||||
| TRP | I:37 | I:88 | 4.0 | 0.016 | E | -96.0 | 132.3 | NA | NA | NA | |||||||||||||
| TRP | L:37 | L:88 | 3.0 | 0.012 | E | -92.8 | 129.6 | NA | NA | NA | |||||||||||||
| 5nw1 | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2017-09-20 | TRP | C:37 | C:88 | 5.0 | 0.02 | E | -94.2 | 131.7 | 5.0 | 0.02 | 0.0 |
9BH HOH |
3.532 4.315 |
CE2 CZ3 |
CD2 O |
||
| TRP | F:37 | F:88 | 4.0 | 0.016 | E | -96.2 | 128.1 | NA | NA | NA | |||||||||||||
| TRP | I:37 | I:88 | 4.0 | 0.016 | E | -97.5 | 130.0 | NA | NA | NA | |||||||||||||
| TRP | L:37 | L:88 | 3.0 | 0.012 | E | -93.1 | 130.6 | NA | NA | NA | |||||||||||||
| 5nw2 | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2017-09-20 | TRP | C:37 | C:88 | 4.0 | 0.016 | E | -95.9 | 132.1 | 4.0 | 0.016 | 0.0 |
9B8 HOH |
3.545 4.412 |
CE2 CZ3 |
CD2 O |
||
| TRP | F:37 | F:88 | 4.0 | 0.016 | E | -100.5 | 132.6 | NA | NA | NA | |||||||||||||
| TRP | I:37 | I:88 | 4.0 | 0.016 | E | -98.3 | 130.4 | NA | NA | NA | |||||||||||||
| TRP | L:37 | L:88 | 3.0 | 0.012 | E | -88.8 | 128.8 | NA | NA | NA | |||||||||||||
| 5t35 | 4 | P40337 | 99.38 | 4e-117 |
X-RAY |
2017-03-08 | TRP | D:37 | D:88 | 9.0 | 0.035 | E | -102.9 | 127.8 | 9.0 | 0.035 | 0.0 |
759 HOH |
3.536 6.128 |
CZ3 CZ2 |
CAE O |
||
| TRP | H:37 | H:88 | 11.0 | 0.043 | E | -101.9 | 127.9 | NA | NA | NA | |||||||||||||
| 6bvb | 1 | P40337 | 99.38 | 4e-117 |
X-RAY |
2018-08-01 | TRP | A:37 | V:88 | 32.0 | 0.125 | E | -98.9 | 132.3 | 15.0 | 0.059 | 0.066 |
D:None:0.067 |
HOH |
5.493 |
HZ2 |
O |
|
| 6gfy | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2018-07-11 | TRP | C:37 | C:88 | 4.0 | 0.016 | E | -92.6 | 128.8 | 4.0 | 0.016 | 0.0 |
EXH HOH |
3.550 4.712 |
CE2 CH2 |
CAQ O |
||
| TRP | F:37 | F:88 | 4.0 | 0.016 | E | -96.0 | 131.5 | NA | NA | NA | |||||||||||||
| TRP | I:37 | I:88 | 4.0 | 0.016 | E | -90.4 | 131.2 | NA | NA | NA | |||||||||||||
| TRP | L:37 | L:88 | 3.0 | 0.012 | E | -89.8 | 129.5 | NA | NA | NA | |||||||||||||
| 6gfz | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2018-07-11 | TRP | C:37 | C:88 | 4.0 | 0.016 | E | -97.7 | 132.0 | 4.0 | 0.016 | 0.0 |
EXE HOH |
3.543 4.355 |
CE2 CH2 |
CAQ O |
||
| TRP | F:37 | F:88 | 4.0 | 0.016 | E | -96.5 | 131.3 | NA | NA | NA | |||||||||||||
| TRP | I:37 | I:88 | 4.0 | 0.016 | E | -98.5 | 129.5 | NA | NA | NA | |||||||||||||
| TRP | L:37 | L:88 | 3.0 | 0.012 | E | -89.3 | 129.4 | NA | NA | NA | |||||||||||||
| 6gmn | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2018-08-08 | TRP | C:37 | C:88 | 27.0 | 0.106 | E | -92.8 | 131.7 | 27.0 | 0.106 | 0.0 |
HOH |
3.694 |
NE1 |
O |
||
| TRP | F:37 | F:88 | 26.0 | 0.102 | E | -93.8 | 131.6 | NA | NA | NA | |||||||||||||
| TRP | L:37 | L:88 | 26.0 | 0.102 | E | -93.5 | 131.6 | NA | NA | NA | |||||||||||||
| 6gmn | 5 | P40337 | 99.38 | 4e-117 |
X-RAY |
2018-08-08 | TRP | I:37 | I:88 | 26.0 | 0.102 | E | -95.3 | 132.7 | NA | NA | NA | ||||||
| 6gmq | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2018-08-22 | TRP | C:37 | C:88 | 38.0 | 0.149 | E | -99.1 | 131.9 | 38.0 | 0.149 | 0.0 |
HOH |
3.956 |
CZ3 |
O |
||
| TRP | F:37 | F:88 | 21.0 | 0.082 | E | -98.7 | 136.9 | NA | NA | NA | |||||||||||||
| TRP | I:37 | I:88 | 26.0 | 0.102 | E | -97.2 | 134.9 | NA | NA | NA | |||||||||||||
| TRP | L:37 | L:88 | 27.0 | 0.106 | E | -96.1 | 137.6 | NA | NA | NA | |||||||||||||
| 6gmx | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2018-08-08 | TRP | C:37 | C:88 | 24.0 | 0.094 | E | -98.0 | 131.6 | 24.0 | 0.094 | 0.0 |
IPA HOH |
3.669 4.518 |
CE2 CH2 |
C3 O |
||
| TRP | F:37 | F:88 | 25.0 | 0.098 | E | -99.5 | 132.7 | NA | NA | NA | |||||||||||||
| TRP | I:37 | I:88 | 25.0 | 0.098 | E | -98.1 | 131.9 | NA | NA | NA | |||||||||||||
| TRP | L:37 | L:88 | 27.0 | 0.106 | E | -96.6 | 132.6 | NA | NA | NA | |||||||||||||
| 6hax | 2 | P40337 | 99.38 | 4e-117 |
X-RAY |
2019-06-12 | TRP | B:37 | B:88 | 31.0 | 0.122 | E | -103.8 | 130.1 | 31.0 | 0.122 | 0.0 |
EDO FWZ EDO HOH |
9.508 3.517 7.589 6.500 |
CZ3 CE2 CE3 CZ2 |
C2 C13 O1 O |
||
| TRP | F:37 | F:88 | 32.0 | 0.125 | E | -103.0 | 129.9 | NA | NA | NA | |||||||||||||
| 6hay | 2 | P40337 | 99.38 | 4e-117 |
X-RAY |
2019-06-12 | TRP | B:37 | B:88 | 32.0 | 0.125 | E | -99.0 | 133.4 | 32.0 | 0.125 | 0.0 |
FX8 HOH |
3.436 3.504 |
CE2 CE3 |
C13 O |
||
| TRP | F:37 | F:88 | 32.0 | 0.125 | E | -99.4 | 133.2 | NA | NA | NA | |||||||||||||
| 6sis | 4 | P40337 | 99.38 | 4e-117 |
X-RAY |
2019-12-04 | TRP | D:37 | D:88 | 27.0 | 0.106 | E | -118.7 | 122.1 | 27.0 | 0.106 | 0.0 |
LFE |
3.583 |
CZ3 |
C32 |
||
| TRP | H:37 | H:88 | 27.0 | 0.106 | E | -118.8 | 122.1 | NA | NA | NA | |||||||||||||
| 7jto | 4 | P40337 | 99.38 | 4e-117 |
X-RAY |
2021-10-06 | TRP | D:37 | L:88 | 31.0 | 0.122 | E | -100.4 | 126.9 | 31.0 | 0.122 | 0.0 |
VKA HOH |
3.443 3.690 |
CE2 CZ3 |
C18 O |
||
| 7jtp | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2021-10-06 | TRP | C:37 | L:88 | 30.0 | 0.118 | E | -94.9 | 133.1 | 30.0 | 0.118 | 0.0 |
GOL X6M HOH |
6.345 3.515 3.563 |
CZ3 CE2 CE3 |
O2 C46 O |
||
| 3zrc | 3 | P40337 | 98.77 | 4e-117 |
X-RAY |
2012-03-07 | TRP | C:38 | C:88 | 5.0 | 0.02 | E | -76.3 | 127.0 | 5.0 | 0.02 | 0.0 |
L8B |
3.485 |
CE2 |
CD2 |
||
| TRP | F:38 | F:88 | 10.0 | 0.039 | E | -91.3 | 124.2 | NA | NA | NA | |||||||||||||
| TRP | I:38 | I:88 | 12.0 | 0.047 | E | -78.9 | 141.2 | NA | NA | NA | |||||||||||||
| TRP | L:38 | L:88 | 12.0 | 0.047 | E | -80.1 | 142.2 | NA | NA | NA | |||||||||||||
| 3zrf | 3 | P40337 | 98.77 | 4e-117 |
X-RAY |
2012-03-07 | TRP | C:38 | C:88 | 21.0 | 0.082 | E | -99.4 | 137.9 | 21.0 | 0.082 | 0.0 | ||||||
| TRP | F:38 | F:88 | 28.0 | 0.11 | E | -86.6 | 145.5 | NA | NA | NA | |||||||||||||
| TRP | I:38 | I:88 | 23.0 | 0.09 | E | -93.0 | 145.2 | NA | NA | NA | |||||||||||||
| TRP | L:38 | L:88 | 28.0 | 0.11 | E | -113.3 | 136.2 | NA | NA | NA | |||||||||||||
| 3ztc | 3 | P40337 | 98.77 | 4e-117 |
X-RAY |
2012-07-25 | TRP | C:38 | C:88 | 20.0 | 0.078 | E | -96.8 | 134.3 | 20.0 | 0.078 | 0.0 |
TR0 HOH |
3.448 6.441 |
CE2 CZ2 |
CD2 O |
||
| TRP | F:38 | F:88 | 9.0 | 0.035 | E | -94.8 | 144.7 | NA | NA | NA | |||||||||||||
| TRP | I:38 | I:88 | 10.0 | 0.039 | E | -87.7 | 134.5 | NA | NA | NA | |||||||||||||
| TRP | L:38 | L:88 | 11.0 | 0.043 | E | -101.5 | 142.6 | NA | NA | NA | |||||||||||||
| 3zun | 3 | P40337 | 98.77 | 4e-117 |
X-RAY |
2012-07-25 | TRP | C:38 | C:88 | 9.0 | 0.035 | E | -100.9 | 132.7 | 9.0 | 0.035 | 0.0 |
ZUN HOH |
3.432 3.645 |
CE2 CH2 |
CD2 O |
||
| TRP | F:38 | F:88 | 10.0 | 0.039 | E | -109.7 | 133.4 | NA | NA | NA | |||||||||||||
| TRP | I:38 | I:88 | 9.0 | 0.035 | E | -93.0 | 135.0 | NA | NA | NA | |||||||||||||
| TRP | L:38 | L:88 | 9.0 | 0.035 | E | -95.7 | 132.6 | NA | NA | NA | |||||||||||||
| 4ajy | 4 | P40337 | 98.77 | 4e-117 |
X-RAY |
2012-11-14 | TRP | D:38 | V:88 | 33.0 | 0.129 | E | -100.6 | 130.3 | 13.0 | 0.051 | 0.078 |
C:Q16665:0.078 |
HOH |
4.158 |
CZ3 |
O |
|
| 4awj | 3 | P40337 | 98.77 | 4e-117 |
X-RAY |
2012-11-14 | TRP | C:38 | C:88 | 21.0 | 0.082 | E | -103.5 | 125.0 | 21.0 | 0.082 | 0.0 |
V6F HOH |
3.489 4.143 |
CE2 CH2 |
C13 O |
||
| TRP | F:38 | F:88 | 22.0 | 0.086 | E | -107.0 | 124.2 | NA | NA | NA | |||||||||||||
| TRP | I:38 | I:88 | 24.0 | 0.094 | E | -97.4 | 128.8 | NA | NA | NA | |||||||||||||
| TRP | L:38 | L:88 | 28.0 | 0.11 | E | -95.1 | 132.1 | NA | NA | NA | |||||||||||||
| 6gmr | 4 | P40337 | 98.77 | 4e-117 |
X-RAY |
2018-08-08 | TRP | D:38 | V:88 | 35.0 | 0.137 | E | -101.0 | 128.3 | 14.0 | 0.055 | 0.082 |
C:None:0.082 |
HOH |
3.585 |
CE3 |
O |
|
| 1lm8 | 3 | P40337 | 100.0 | 6e-117 |
X-RAY |
2002-06-12 | TRP | C:35 | V:88 | 32.0 | 0.125 | E | -97.7 | 134.0 | 14.0 | 0.055 | 0.07 |
D:Q16665:0.071 |
HOH |
3.667 |
CH2 |
O |
|
| 1vcb | 3 | P40337 | 100.0 | 6e-117 |
X-RAY |
1999-04-21 | TRP | C:35 | C:88 | 25.0 | 0.098 | E | -90.3 | 134.4 | 25.0 | 0.098 | 0.0 |
HOH |
3.984 |
CE2 |
O |
||
| TRP | F:35 | F:88 | 24.0 | 0.094 | E | -90.4 | 134.3 | NA | NA | NA | |||||||||||||
| TRP | I:35 | I:88 | 24.0 | 0.094 | E | -90.5 | 136.9 | NA | NA | NA | |||||||||||||
| TRP | L:35 | L:88 | 25.0 | 0.098 | E | -91.6 | 135.8 | NA | NA | NA | |||||||||||||
| 5n4w | 2 | P40337 | 100.0 | 6e-117 |
X-RAY |
2017-06-07 | TRP | B:35 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 6gfx | 3 | P40337 | 100.0 | 6e-117 |
X-RAY |
2018-07-11 | TRP | C:35 | C:88 | 30.0 | 0.118 | E | -93.7 | 129.9 | 14.0 | 0.055 | 0.063 |
D:None:0.063 |
HOH |
4.035 |
CZ3 |
O |
|
| 6i7q | 4 | P40337 | 100.0 | 6e-117 |
X-RAY |
2019-11-27 | TRP | D:35 | V:88 | 20.0 | 0.078 | E | -100.0 | 132.3 | 3.0 | 0.012 | 0.066 |
C:Q99814:0.067 |
HOH |
3.285 |
HZ3 |
O |
|
| 6i7r | 4 | P40337 | 100.0 | 6e-117 |
X-RAY |
2019-11-27 | TRP | D:35 | V:88 | 23.0 | 0.09 | E | -97.4 | 127.5 | 4.0 | 0.016 | 0.074 |
C:Q99814:0.075 |
HOH |
3.506 |
HE3 |
O |
|
| 6r7f | 9 | P40337 | 100.0 | 6e-117 |
EM |
2019-08-28 | TRP | I:35 | V:88 | 36.0 | 0.141 | E | -109.1 | 133.3 | 36.0 | 0.141 | 0.0 | ||||||
| 7khh | 3 | P40337 | 100.0 | 6e-116 |
X-RAY |
2021-02-24 | TRP | C:50 | C:88 | 34.0 | 0.133 | E | -96.1 | 129.5 | 26.0 | 0.102 | 0.031 |
D:O60885:0.031 |
WEP HOH |
2.926 4.989 |
CD1 CH2 |
H21 O |
|
| 7cjb | 1 | P40337 | 100.0 | 8e-116 |
X-RAY |
2021-07-14 | TRP | A:38 | A:88 | 21.0 | 0.082 | E | -98.2 | 132.3 | 4.0 | 0.016 | 0.066 |
D:Q13546:0.067 |
|||||
| TRP | E:38 | E:88 | 22.0 | 0.086 | E | -96.8 | 131.9 | NA | NA | NA | |||||||||||||
| TRP | I:38 | I:88 | 20.0 | 0.078 | E | -97.0 | 132.4 | NA | NA | NA | |||||||||||||
| TRP | M:38 | M:88 | 19.0 | 0.075 | E | -96.2 | 132.0 | NA | NA | NA | |||||||||||||
| 6zhc | 1 | P40337 | 100.0 | 4e-113 |
X-RAY |
2020-08-05 | TRP | A:30 | AAA:88 | 23.0 | 0.09 | E | -95.4 | 131.6 | 14.0 | 0.055 | 0.035 |
D:Q07817:0.035 |
QL8 EDO IOD IOD IOD HOH |
3.463 8.991 9.957 9.413 9.496 3.758 |
CE2 O N CH2 CH2 CZ3 |
C18 C1 I I I O |
|
| 7pi4 | 1 | P40337 | 100.0 | 4e-113 |
X-RAY |
2021-09-29 | TRP | A:30 | AAA:88 | 32.0 | 0.125 | E | -98.3 | 132.0 | 32.0 | 0.125 | 0.0 |
7QB EDO EDO PEG HOH |
3.426 5.756 4.082 7.208 4.702 |
CE2 CE3 CZ3 CZ3 CH2 |
C24 C2 C1 O1 O |
||
| 6fmi | 3 | P40337 | 99.34 | 1e-109 |
X-RAY |
2018-04-11 | TRP | C:37 | C:88 | 6.0 | 0.024 | E | -92.2 | 132.9 | 6.0 | 0.024 | 0.0 |
DV2 HOH |
3.618 6.910 |
CE2 CZ2 |
CAO O |
||
| TRP | F:37 | F:88 | 5.0 | 0.02 | E | -88.2 | 136.7 | NA | NA | NA | |||||||||||||
| 6fmj | 3 | P40337 | 99.34 | 1e-109 |
X-RAY |
2018-04-11 | TRP | C:37 | C:88 | 5.0 | 0.02 | E | -96.8 | 128.4 | 5.0 | 0.02 | 0.0 |
DV5 HOH |
3.420 4.028 |
CE2 CZ3 |
CD2 O |
||
| TRP | F:37 | F:88 | 4.0 | 0.016 | E | -97.5 | 126.8 | NA | NA | NA | |||||||||||||
| TRP | I:37 | I:88 | 4.0 | 0.016 | E | -94.2 | 127.9 | NA | NA | NA | |||||||||||||
| TRP | L:37 | L:88 | 4.0 | 0.016 | E | -94.5 | 126.3 | NA | NA | NA | |||||||||||||
| 6fmk | 3 | P40337 | 99.34 | 1e-109 |
X-RAY |
2018-04-11 | TRP | C:37 | C:88 | 26.0 | 0.102 | E | -93.2 | 127.4 | 26.0 | 0.102 | 0.0 |
DV8 HOH |
3.584 4.371 |
CE2 CH2 |
CAO O |
||
| TRP | F:37 | F:88 | 25.0 | 0.098 | E | -99.3 | 128.9 | NA | NA | NA | |||||||||||||
| TRP | I:37 | I:88 | 27.0 | 0.106 | E | -90.3 | 131.0 | NA | NA | NA | |||||||||||||
| TRP | L:37 | L:88 | 25.0 | 0.098 | E | -98.6 | 126.4 | NA | NA | NA | |||||||||||||
| 6hr2 | 2 | P40337 | 100.0 | 3e-108 |
X-RAY |
2019-06-12 | TRP | B:28 | B:88 | 33.0 | 0.129 | E | -100.3 | 127.2 | 32.0 | 0.125 | 0.004 |
A:P51532:0.004 |
FWZ HOH |
2.421 2.833 |
HH2 HZ3 |
H7 O |
|
| TRP | F:28 | F:88 | 34.0 | 0.133 | E | -102.0 | 127.4 | NA | NA | NA | |||||||||||||
| 6r6h | 12 | P40337 | 100.0 | 3e-107 |
EM |
2019-08-28 | TRP | L:29 | V:88 | 2.0 | 0.008 | E | -129.2 | 128.3 | 2.0 | 0.008 | 0.0 | ||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p40337-f1 | 1 | P40337 | 100.0 | 2e-156 | TRP | A:88 | A:88 | 35.0 | 0.137 | E | -92.0 | 133.0 | |