Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr3 | 10183823 | . | T | A | CCDS2597.1:NM_000551.3:c.292Tac>Aac_NP_000542.1:p.98Y>N | Homo sapiens von Hippel-Lindau tumor suppressor (VHL), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 4wqo | 1 | P40337 | 100.0 | 4e-156 |
X-RAY |
2015-03-04 | TYR | A:118 | A:98 | 100.0 | 0.435 | -131.1 | 164.7 | 100.0 | 0.435 | 0.0 | |||||||
| 7q2j | 3 | P40337 | 94.25 | 1e-118 |
X-RAY |
2021-11-24 | TYR | C:82 | C:98 | 101.0 | 0.439 | -118.2 | 174.2 | 101.0 | 0.439 | 0.0 |
8KH |
2.788 |
OH |
O3 |
|||
| 4b9k | 3 | P40337 | 95.32 | 3e-118 |
X-RAY |
2012-10-24 | TYR | C:56 | C:98 | 85.0 | 0.37 | -117.6 | 167.5 | 85.0 | 0.37 | 0.0 |
TG0 HOH |
2.651 2.624 |
OH O |
O24 O |
|||
| TYR | F:56 | F:98 | 88.0 | 0.383 | -118.1 | 167.0 | NA | NA | NA | ||||||||||||||
| TYR | I:56 | I:98 | 86.0 | 0.374 | -117.6 | 164.0 | NA | NA | NA | ||||||||||||||
| TYR | L:56 | L:98 | 86.0 | 0.374 | -120.9 | 165.8 | NA | NA | NA | ||||||||||||||
| 1lqb | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2002-07-03 | TYR | C:47 | C:98 | 89.0 | 0.387 | -132.1 | 167.3 | 32.0 | 0.139 | 0.248 |
D:Q16665:0.248 |
HOH |
7.979 |
O |
O |
||
| 3ztd | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2012-07-25 | TYR | C:47 | C:98 | 31.0 | 0.135 | -114.7 | 169.9 | 31.0 | 0.135 | 0.0 |
ZTD |
2.481 |
OH |
O |
|||
| TYR | F:47 | F:98 | 35.0 | 0.152 | -105.4 | 174.9 | NA | NA | NA | ||||||||||||||
| TYR | I:47 | I:98 | 34.0 | 0.148 | -114.8 | 173.1 | NA | NA | NA | ||||||||||||||
| TYR | L:47 | L:98 | 31.0 | 0.135 | -124.6 | 170.9 | NA | NA | NA | ||||||||||||||
| 4b95 | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2012-10-24 | TYR | C:47 | C:98 | 90.0 | 0.391 | -119.2 | 168.5 | 90.0 | 0.391 | 0.0 |
UCK HOH |
2.823 7.496 |
OH OH |
O15 O |
|||
| TYR | F:47 | F:98 | 86.0 | 0.374 | -118.3 | 164.2 | NA | NA | NA | ||||||||||||||
| TYR | I:47 | I:98 | 103.0 | 0.448 | -120.4 | 163.2 | NA | NA | NA | ||||||||||||||
| TYR | L:47 | L:98 | 88.0 | 0.383 | -120.3 | 167.4 | NA | NA | NA | ||||||||||||||
| 4bks | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2013-11-27 | TYR | C:47 | C:98 | 30.0 | 0.13 | -117.8 | 165.3 | 30.0 | 0.13 | 0.0 |
X6C HOH |
2.702 3.412 |
OH OH |
O O |
|||
| TYR | F:47 | F:98 | 27.0 | 0.117 | -117.5 | 165.0 | NA | NA | NA | ||||||||||||||
| TYR | I:47 | I:98 | 26.0 | 0.113 | -117.9 | 165.3 | NA | NA | NA | ||||||||||||||
| TYR | L:47 | L:98 | 38.0 | 0.165 | -118.3 | 163.1 | NA | NA | NA | ||||||||||||||
| 4bkt | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2013-11-27 | TYR | C:47 | C:98 | 91.0 | 0.396 | -120.4 | 163.6 | 91.0 | 0.396 | 0.0 |
QD0 HOH |
2.653 2.985 |
OH O |
O13 O |
|||
| TYR | F:47 | F:98 | 71.0 | 0.309 | -119.3 | 162.2 | NA | NA | NA | ||||||||||||||
| TYR | I:47 | I:98 | 85.0 | 0.37 | -119.4 | 161.1 | NA | NA | NA | ||||||||||||||
| TYR | L:47 | L:98 | 72.0 | 0.313 | -119.9 | 162.1 | NA | NA | NA | ||||||||||||||
| 4w9c | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2014-09-10 | TYR | C:47 | C:98 | 24.0 | 0.104 | -126.2 | 165.6 | 24.0 | 0.104 | 0.0 |
3JG HOH |
2.673 3.377 |
OH C |
O O |
|||
| TYR | F:47 | F:98 | 26.0 | 0.113 | -118.8 | 170.8 | NA | NA | NA | ||||||||||||||
| TYR | I:47 | I:98 | 30.0 | 0.13 | -114.7 | 168.7 | NA | NA | NA | ||||||||||||||
| TYR | L:47 | L:98 | 32.0 | 0.139 | -125.8 | 167.3 | NA | NA | NA | ||||||||||||||
| 4w9d | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2014-09-10 | TYR | C:47 | C:98 | 24.0 | 0.104 | -125.1 | 169.9 | 24.0 | 0.104 | 0.0 |
3JK HOH |
2.744 6.283 |
OH C |
O O |
|||
| TYR | F:47 | F:98 | 28.0 | 0.122 | -115.8 | 171.7 | NA | NA | NA | ||||||||||||||
| TYR | I:47 | I:98 | 29.0 | 0.126 | -119.1 | 171.5 | NA | NA | NA | ||||||||||||||
| TYR | L:47 | L:98 | 31.0 | 0.135 | -124.7 | 171.1 | NA | NA | NA | ||||||||||||||
| 4w9e | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2014-09-10 | TYR | C:47 | C:98 | 23.0 | 0.1 | -122.5 | 174.5 | 23.0 | 0.1 | 0.0 |
3JT HOH |
2.572 5.302 |
OH OH |
O O |
|||
| TYR | F:47 | F:98 | 24.0 | 0.104 | -119.3 | 172.1 | NA | NA | NA | ||||||||||||||
| TYR | I:47 | I:98 | 24.0 | 0.104 | -114.1 | 171.4 | NA | NA | NA | ||||||||||||||
| TYR | L:47 | L:98 | 27.0 | 0.117 | -123.2 | 170.6 | NA | NA | NA | ||||||||||||||
| 4w9f | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2014-09-10 | TYR | C:47 | C:98 | 20.0 | 0.087 | -124.5 | 171.8 | 20.0 | 0.087 | 0.0 |
3JU HOH |
2.626 3.587 |
OH CE2 |
O O |
|||
| TYR | F:47 | F:98 | 20.0 | 0.087 | -123.5 | 170.6 | NA | NA | NA | ||||||||||||||
| TYR | I:47 | I:98 | 33.0 | 0.143 | -124.0 | 169.2 | NA | NA | NA | ||||||||||||||
| TYR | L:47 | L:98 | 30.0 | 0.13 | -122.9 | 171.5 | NA | NA | NA | ||||||||||||||
| 4w9g | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2014-09-10 | TYR | C:47 | C:98 | 26.0 | 0.113 | -123.7 | 171.1 | 26.0 | 0.113 | 0.0 |
3JV HOH |
2.580 3.633 |
OH CD2 |
O O |
|||
| TYR | F:47 | F:98 | 20.0 | 0.087 | -119.6 | 168.4 | NA | NA | NA | ||||||||||||||
| TYR | I:47 | I:98 | 21.0 | 0.091 | -113.6 | 165.4 | NA | NA | NA | ||||||||||||||
| TYR | L:47 | L:98 | 25.0 | 0.109 | -120.8 | 167.1 | NA | NA | NA | ||||||||||||||
| 4w9h | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2014-09-10 | TYR | C:47 | C:98 | 22.0 | 0.096 | -127.4 | 168.9 | 22.0 | 0.096 | 0.0 |
3JF HOH |
2.595 3.034 |
OH O |
O O |
|||
| TYR | F:47 | F:98 | 25.0 | 0.109 | -122.3 | 168.9 | NA | NA | NA | ||||||||||||||
| TYR | I:47 | I:98 | 27.0 | 0.117 | -123.9 | 174.1 | NA | NA | NA | ||||||||||||||
| TYR | L:47 | L:98 | 29.0 | 0.126 | -118.0 | 172.0 | NA | NA | NA | ||||||||||||||
| 4w9i | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2014-09-10 | TYR | C:47 | C:98 | 18.0 | 0.078 | -116.9 | 168.2 | 18.0 | 0.078 | 0.0 |
3JS HOH |
2.587 3.802 |
OH CD1 |
O O |
|||
| TYR | F:47 | F:98 | 20.0 | 0.087 | -108.7 | 170.9 | NA | NA | NA | ||||||||||||||
| TYR | I:47 | I:98 | 24.0 | 0.104 | -113.3 | 171.8 | NA | NA | NA | ||||||||||||||
| TYR | L:47 | L:98 | 24.0 | 0.104 | -122.1 | 169.2 | NA | NA | NA | ||||||||||||||
| 4w9j | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2014-09-10 | TYR | C:47 | C:98 | 20.0 | 0.087 | -121.8 | 171.6 | 20.0 | 0.087 | 0.0 |
3JH HOH |
2.581 7.273 |
OH O |
OAY O |
|||
| TYR | F:47 | F:98 | 19.0 | 0.083 | -125.5 | 168.6 | NA | NA | NA | ||||||||||||||
| TYR | I:47 | I:98 | 22.0 | 0.096 | -121.1 | 172.5 | NA | NA | NA | ||||||||||||||
| TYR | L:47 | L:98 | 24.0 | 0.104 | -122.2 | 171.6 | NA | NA | NA | ||||||||||||||
| 4w9k | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2014-09-10 | TYR | C:47 | C:98 | 26.0 | 0.113 | -120.5 | 169.1 | 26.0 | 0.113 | 0.0 |
3JO HOH |
2.599 4.801 |
OH O |
OAG O |
|||
| TYR | F:47 | F:98 | 22.0 | 0.096 | -119.1 | 172.0 | NA | NA | NA | ||||||||||||||
| TYR | I:47 | I:98 | 27.0 | 0.117 | -116.9 | 176.9 | NA | NA | NA | ||||||||||||||
| TYR | L:47 | L:98 | 24.0 | 0.104 | -123.2 | 169.4 | NA | NA | NA | ||||||||||||||
| 4w9l | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2014-09-10 | TYR | C:47 | C:98 | 24.0 | 0.104 | -125.4 | 169.5 | 24.0 | 0.104 | 0.0 |
3JJ HOH |
2.600 3.680 |
OH CG |
OAW O |
|||
| TYR | F:47 | F:98 | 22.0 | 0.096 | -119.1 | 174.3 | NA | NA | NA | ||||||||||||||
| TYR | I:47 | I:98 | 29.0 | 0.126 | -125.0 | 173.5 | NA | NA | NA | ||||||||||||||
| TYR | L:47 | L:98 | 22.0 | 0.096 | -129.1 | 166.7 | NA | NA | NA | ||||||||||||||
| 5lli | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2016-11-09 | TYR | C:47 | C:98 | 22.0 | 0.096 | -120.0 | 170.7 | 22.0 | 0.096 | 0.0 |
6Z3 HOH |
2.560 3.017 |
OH O |
O O |
|||
| TYR | F:47 | F:98 | 24.0 | 0.104 | -115.4 | 173.6 | NA | NA | NA | ||||||||||||||
| TYR | I:47 | I:98 | 29.0 | 0.126 | -115.8 | 176.8 | NA | NA | NA | ||||||||||||||
| TYR | L:47 | L:98 | 30.0 | 0.13 | -123.9 | 168.7 | NA | NA | NA | ||||||||||||||
| 5nvv | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2017-09-20 | TYR | C:47 | C:98 | 21.0 | 0.091 | -120.6 | 168.6 | 21.0 | 0.091 | 0.0 |
9BT HOH |
2.604 3.023 |
OH O |
O O |
|||
| TYR | F:47 | F:98 | 22.0 | 0.096 | -116.1 | 171.3 | NA | NA | NA | ||||||||||||||
| TYR | I:47 | I:98 | 27.0 | 0.117 | -119.1 | 172.1 | NA | NA | NA | ||||||||||||||
| TYR | L:47 | L:98 | 31.0 | 0.135 | -122.3 | 170.4 | NA | NA | NA | ||||||||||||||
| 5nvw | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2017-09-20 | TYR | C:47 | C:98 | 23.0 | 0.1 | -126.7 | 168.7 | 23.0 | 0.1 | 0.0 |
9BW HOH |
2.707 3.005 |
OH O |
O O |
|||
| TYR | F:47 | F:98 | 24.0 | 0.104 | -118.0 | 171.5 | NA | NA | NA | ||||||||||||||
| TYR | I:47 | I:98 | 27.0 | 0.117 | -121.4 | 174.8 | NA | NA | NA | ||||||||||||||
| TYR | L:47 | L:98 | 30.0 | 0.13 | -124.0 | 166.0 | NA | NA | NA | ||||||||||||||
| 5nvx | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2017-09-20 | TYR | C:47 | C:98 | 23.0 | 0.1 | -123.6 | 168.0 | 23.0 | 0.1 | 0.0 |
4YY HOH |
2.698 2.979 |
OH O |
O O |
|||
| TYR | F:47 | F:98 | 23.0 | 0.1 | -115.2 | 172.1 | NA | NA | NA | ||||||||||||||
| TYR | I:47 | I:98 | 27.0 | 0.117 | -118.5 | 171.2 | NA | NA | NA | ||||||||||||||
| TYR | L:47 | L:98 | 32.0 | 0.139 | -123.4 | 168.8 | NA | NA | NA | ||||||||||||||
| 5nvy | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2017-09-20 | TYR | C:47 | C:98 | 16.0 | 0.07 | -119.9 | 170.2 | 16.0 | 0.07 | 0.0 |
9B5 HOH |
2.456 3.659 |
OH CD2 |
OAE O |
|||
| TYR | F:47 | F:98 | 18.0 | 0.078 | -110.7 | 170.2 | NA | NA | NA | ||||||||||||||
| TYR | I:47 | I:98 | 22.0 | 0.096 | -114.3 | 170.5 | NA | NA | NA | ||||||||||||||
| TYR | L:47 | L:98 | 23.0 | 0.1 | -116.7 | 169.7 | NA | NA | NA | ||||||||||||||
| 5nvz | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2017-09-20 | TYR | C:47 | C:98 | 25.0 | 0.109 | -121.4 | 168.4 | 25.0 | 0.109 | 0.0 |
9BN HOH |
2.438 7.221 |
OH CE2 |
O O |
|||
| TYR | F:47 | F:98 | 25.0 | 0.109 | -116.0 | 169.4 | NA | NA | NA | ||||||||||||||
| TYR | I:47 | I:98 | 27.0 | 0.117 | -120.2 | 170.2 | NA | NA | NA | ||||||||||||||
| TYR | L:47 | L:98 | 32.0 | 0.139 | -128.8 | 167.4 | NA | NA | NA | ||||||||||||||
| 5nw0 | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2017-09-20 | TYR | C:47 | C:98 | 24.0 | 0.104 | -125.6 | 168.0 | 24.0 | 0.104 | 0.0 |
9BK HOH |
2.683 3.059 |
OH O |
O O |
|||
| TYR | F:47 | F:98 | 25.0 | 0.109 | -116.6 | 170.8 | NA | NA | NA | ||||||||||||||
| TYR | I:47 | I:98 | 30.0 | 0.13 | -119.8 | 175.2 | NA | NA | NA | ||||||||||||||
| TYR | L:47 | L:98 | 30.0 | 0.13 | -121.4 | 168.7 | NA | NA | NA | ||||||||||||||
| 5nw1 | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2017-09-20 | TYR | C:47 | C:98 | 26.0 | 0.113 | -122.8 | 169.0 | 26.0 | 0.113 | 0.0 |
9BH HOH |
2.692 2.768 |
OH O |
O O |
|||
| TYR | F:47 | F:98 | 26.0 | 0.113 | -118.4 | 171.2 | NA | NA | NA | ||||||||||||||
| TYR | I:47 | I:98 | 28.0 | 0.122 | -122.2 | 172.8 | NA | NA | NA | ||||||||||||||
| TYR | L:47 | L:98 | 24.0 | 0.104 | -121.7 | 168.1 | NA | NA | NA | ||||||||||||||
| 5nw2 | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2017-09-20 | TYR | C:47 | C:98 | 24.0 | 0.104 | -125.6 | 169.3 | 24.0 | 0.104 | 0.0 |
9B8 HOH |
2.738 3.064 |
OH O |
O O |
|||
| TYR | F:47 | F:98 | 26.0 | 0.113 | -119.0 | 171.7 | NA | NA | NA | ||||||||||||||
| TYR | I:47 | I:98 | 27.0 | 0.117 | -123.1 | 174.2 | NA | NA | NA | ||||||||||||||
| TYR | L:47 | L:98 | 29.0 | 0.126 | -123.4 | 168.0 | NA | NA | NA | ||||||||||||||
| 5t35 | 4 | P40337 | 99.38 | 4e-117 |
X-RAY |
2017-03-08 | TYR | D:47 | D:98 | 36.0 | 0.157 | -120.2 | 170.9 | 36.0 | 0.157 | 0.0 |
759 HOH |
2.565 6.947 |
OH OH |
O O |
|||
| TYR | H:47 | H:98 | 37.0 | 0.161 | -120.3 | 170.6 | NA | NA | NA | ||||||||||||||
| 6bvb | 1 | P40337 | 99.38 | 4e-117 |
X-RAY |
2018-08-01 | TYR | A:47 | V:98 | 99.0 | 0.43 | -127.3 | 164.3 | 38.0 | 0.165 | 0.265 |
D:None:0.265 |
HOH |
3.204 |
HE2 |
O |
||
| 6gfy | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2018-07-11 | TYR | C:47 | C:98 | 28.0 | 0.122 | -125.3 | 170.7 | 28.0 | 0.122 | 0.0 |
EXH HOH |
2.577 3.730 |
OH CD1 |
OAG O |
|||
| TYR | F:47 | F:98 | 24.0 | 0.104 | -118.8 | 170.3 | NA | NA | NA | ||||||||||||||
| TYR | I:47 | I:98 | 27.0 | 0.117 | -115.8 | 172.2 | NA | NA | NA | ||||||||||||||
| TYR | L:47 | L:98 | 32.0 | 0.139 | -126.9 | 172.4 | NA | NA | NA | ||||||||||||||
| 6gfz | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2018-07-11 | TYR | C:47 | C:98 | 20.0 | 0.087 | -122.0 | 169.8 | 20.0 | 0.087 | 0.0 |
EXE HOH |
2.782 2.924 |
OH O |
OAG O |
|||
| TYR | F:47 | F:98 | 23.0 | 0.1 | -118.0 | 171.2 | NA | NA | NA | ||||||||||||||
| TYR | I:47 | I:98 | 29.0 | 0.126 | -116.5 | 175.7 | NA | NA | NA | ||||||||||||||
| TYR | L:47 | L:98 | 32.0 | 0.139 | -121.3 | 175.4 | NA | NA | NA | ||||||||||||||
| 6gmn | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2018-08-08 | TYR | C:47 | C:98 | 80.0 | 0.348 | -121.7 | 168.5 | 80.0 | 0.348 | 0.0 |
HOH |
3.213 |
OH |
O |
|||
| TYR | F:47 | F:98 | 79.0 | 0.343 | -122.9 | 168.0 | NA | NA | NA | ||||||||||||||
| TYR | L:47 | L:98 | 88.0 | 0.383 | -121.7 | 167.3 | NA | NA | NA | ||||||||||||||
| 6gmn | 5 | P40337 | 99.38 | 4e-117 |
X-RAY |
2018-08-08 | TYR | I:47 | I:98 | 87.0 | 0.378 | -120.8 | 168.3 | NA | NA | NA | |||||||
| 6gmq | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2018-08-22 | TYR | C:47 | C:98 | 93.0 | 0.404 | -111.3 | 169.1 | 93.0 | 0.404 | 0.0 |
HOH |
4.661 |
O |
O |
|||
| TYR | F:47 | F:98 | 65.0 | 0.283 | -109.4 | 162.3 | NA | NA | NA | ||||||||||||||
| TYR | I:47 | I:98 | 91.0 | 0.396 | -107.7 | 164.4 | NA | NA | NA | ||||||||||||||
| TYR | L:47 | L:98 | 90.0 | 0.391 | -112.1 | 168.0 | NA | NA | NA | ||||||||||||||
| 6gmx | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2018-08-08 | TYR | C:47 | C:98 | 85.0 | 0.37 | -111.0 | 170.0 | 85.0 | 0.37 | 0.0 |
IPA HOH |
3.251 5.797 |
OH CE2 |
C1 O |
|||
| TYR | F:47 | F:98 | 82.0 | 0.357 | -113.7 | 166.8 | NA | NA | NA | ||||||||||||||
| TYR | I:47 | I:98 | 84.0 | 0.365 | -112.9 | 169.7 | NA | NA | NA | ||||||||||||||
| TYR | L:47 | L:98 | 88.0 | 0.383 | -115.8 | 172.4 | NA | NA | NA | ||||||||||||||
| 6hax | 2 | P40337 | 99.38 | 4e-117 |
X-RAY |
2019-06-12 | TYR | B:47 | B:98 | 100.0 | 0.435 | -117.7 | 164.7 | 100.0 | 0.435 | 0.0 |
EDO FWZ EDO EDO HOH |
6.339 2.816 3.398 7.111 2.922 |
OH OH CA CE2 O |
C2 O16 O2 O2 O |
|||
| TYR | F:47 | F:98 | 102.0 | 0.443 | -117.9 | 166.1 | NA | NA | NA | ||||||||||||||
| 6hay | 2 | P40337 | 99.38 | 4e-117 |
X-RAY |
2019-06-12 | TYR | B:47 | B:98 | 97.0 | 0.422 | -112.9 | 167.1 | 97.0 | 0.422 | 0.0 |
FX8 EDO HOH |
2.716 7.428 2.787 |
OH CE2 O |
O16 O1 O |
|||
| TYR | F:47 | F:98 | 99.0 | 0.43 | -112.6 | 166.4 | NA | NA | NA | ||||||||||||||
| 6sis | 4 | P40337 | 99.38 | 4e-117 |
X-RAY |
2019-12-04 | TYR | D:47 | D:98 | 105.0 | 0.457 | -101.0 | 166.1 | 105.0 | 0.457 | 0.0 |
LFE |
2.615 |
OH |
O57 |
|||
| TYR | H:47 | H:98 | 105.0 | 0.457 | -100.6 | 165.2 | NA | NA | NA | ||||||||||||||
| 7jto | 4 | P40337 | 99.38 | 4e-117 |
X-RAY |
2021-10-06 | TYR | D:47 | L:98 | 101.0 | 0.439 | -112.1 | 172.7 | 101.0 | 0.439 | 0.0 |
VKA EDO HOH |
2.586 7.090 2.775 |
OH CE2 O |
O15 C1 O |
|||
| 7jtp | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2021-10-06 | TYR | C:47 | L:98 | 100.0 | 0.435 | -120.9 | 167.3 | 92.0 | 0.4 | 0.035 |
D:P61964:0.035 |
GOL X6M HOH |
3.867 2.688 3.141 |
CE2 OH OH |
O1 O2 O |
||
| 3zrc | 3 | P40337 | 98.77 | 4e-117 |
X-RAY |
2012-03-07 | TYR | C:48 | C:98 | 32.0 | 0.139 | -91.0 | -175.8 | 32.0 | 0.139 | 0.0 |
L8B |
2.952 |
OH |
CB |
|||
| TYR | F:48 | F:98 | 31.0 | 0.135 | -100.8 | -178.1 | NA | NA | NA | ||||||||||||||
| TYR | I:48 | I:98 | 26.0 | 0.113 | -125.3 | 171.4 | NA | NA | NA | ||||||||||||||
| TYR | L:48 | L:98 | 27.0 | 0.117 | -123.4 | 172.0 | NA | NA | NA | ||||||||||||||
| 3zrf | 3 | P40337 | 98.77 | 4e-117 |
X-RAY |
2012-03-07 | TYR | C:48 | C:98 | 82.0 | 0.357 | -115.2 | 153.6 | 82.0 | 0.357 | 0.0 | |||||||
| TYR | F:48 | F:98 | 81.0 | 0.352 | -120.2 | -174.3 | NA | NA | NA | ||||||||||||||
| TYR | I:48 | I:98 | 85.0 | 0.37 | -119.4 | 172.1 | NA | NA | NA | ||||||||||||||
| TYR | L:48 | L:98 | 80.0 | 0.348 | -122.3 | 165.0 | NA | NA | NA | ||||||||||||||
| 3ztc | 3 | P40337 | 98.77 | 4e-117 |
X-RAY |
2012-07-25 | TYR | C:48 | C:98 | 40.0 | 0.174 | -123.7 | 174.4 | 40.0 | 0.174 | 0.0 |
TR0 HOH |
2.600 7.997 |
OH OH |
O O |
|||
| TYR | F:48 | F:98 | 35.0 | 0.152 | -121.4 | -178.5 | NA | NA | NA | ||||||||||||||
| TYR | I:48 | I:98 | 31.0 | 0.135 | -123.8 | 166.0 | NA | NA | NA | ||||||||||||||
| TYR | L:48 | L:98 | 29.0 | 0.126 | -123.7 | 167.7 | NA | NA | NA | ||||||||||||||
| 3zun | 3 | P40337 | 98.77 | 4e-117 |
X-RAY |
2012-07-25 | TYR | C:48 | C:98 | 30.0 | 0.13 | -121.9 | 171.4 | 30.0 | 0.13 | 0.0 |
ZUN HOH |
2.664 6.742 |
OH O |
O O |
|||
| TYR | F:48 | F:98 | 21.0 | 0.091 | -108.3 | 171.1 | NA | NA | NA | ||||||||||||||
| TYR | I:48 | I:98 | 28.0 | 0.122 | -105.9 | 172.0 | NA | NA | NA | ||||||||||||||
| TYR | L:48 | L:98 | 28.0 | 0.122 | -112.8 | 171.5 | NA | NA | NA | ||||||||||||||
| 4ajy | 4 | P40337 | 98.77 | 4e-117 |
X-RAY |
2012-11-14 | TYR | D:48 | V:98 | 98.0 | 0.426 | -121.7 | 164.8 | 36.0 | 0.157 | 0.269 |
C:Q16665:0.27 |
HOH |
4.484 |
CB |
O |
||
| 4awj | 3 | P40337 | 98.77 | 4e-117 |
X-RAY |
2012-11-14 | TYR | C:48 | C:98 | 88.0 | 0.383 | -120.1 | 163.7 | 88.0 | 0.383 | 0.0 |
V6F HOH |
2.592 4.984 |
OH O |
O08 O |
|||
| TYR | F:48 | F:98 | 73.0 | 0.317 | -108.8 | 164.4 | NA | NA | NA | ||||||||||||||
| TYR | I:48 | I:98 | 73.0 | 0.317 | -112.5 | 165.6 | NA | NA | NA | ||||||||||||||
| TYR | L:48 | L:98 | 97.0 | 0.422 | -114.2 | 168.0 | NA | NA | NA | ||||||||||||||
| 6gmr | 4 | P40337 | 98.77 | 4e-117 |
X-RAY |
2018-08-08 | TYR | D:48 | V:98 | 103.0 | 0.448 | -121.6 | 163.4 | 39.0 | 0.17 | 0.278 |
C:None:0.278 |
HOH |
3.192 |
OH |
O |
||
| 1lm8 | 3 | P40337 | 100.0 | 6e-117 |
X-RAY |
2002-06-12 | TYR | C:45 | V:98 | 99.0 | 0.43 | -128.9 | 162.7 | 40.0 | 0.174 | 0.256 |
D:Q16665:0.257 |
HOH |
3.999 |
CE1 |
O |
||
| 1vcb | 3 | P40337 | 100.0 | 6e-117 |
X-RAY |
1999-04-21 | TYR | C:45 | C:98 | 87.0 | 0.378 | -101.9 | 171.1 | 87.0 | 0.378 | 0.0 |
HOH |
4.171 |
OH |
O |
|||
| TYR | F:45 | F:98 | 89.0 | 0.387 | -103.1 | 171.5 | NA | NA | NA | ||||||||||||||
| TYR | I:45 | I:98 | 90.0 | 0.391 | -103.3 | 170.7 | NA | NA | NA | ||||||||||||||
| TYR | L:45 | L:98 | 87.0 | 0.378 | -102.5 | 170.6 | NA | NA | NA | ||||||||||||||
| 5n4w | 2 | P40337 | 100.0 | 6e-117 |
X-RAY |
2017-06-07 | TYR | B:45 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 6gfx | 3 | P40337 | 100.0 | 6e-117 |
X-RAY |
2018-07-11 | TYR | C:45 | C:98 | 104.0 | 0.452 | -118.8 | 164.9 | 41.0 | 0.178 | 0.274 |
D:None:0.274 |
HOH |
4.464 |
CB |
O |
||
| 6i7q | 4 | P40337 | 100.0 | 6e-117 |
X-RAY |
2019-11-27 | TYR | D:45 | V:98 | 87.0 | 0.378 | -123.6 | 167.6 | 33.0 | 0.143 | 0.235 |
C:Q99814:0.235 |
HOH |
2.908 |
OH |
O |
||
| 6i7r | 4 | P40337 | 100.0 | 6e-117 |
X-RAY |
2019-11-27 | TYR | D:45 | V:98 | 87.0 | 0.378 | -125.3 | 162.9 | 34.0 | 0.148 | 0.23 |
C:Q99814:0.23 |
HOH |
3.012 |
OH |
O |
||
| 6r7f | 9 | P40337 | 100.0 | 6e-117 |
EM |
2019-08-28 | TYR | I:45 | V:98 | 84.0 | 0.365 | -135.6 | 172.0 | 84.0 | 0.365 | 0.0 | |||||||
| 7khh | 3 | P40337 | 100.0 | 6e-116 |
X-RAY |
2021-02-24 | TYR | C:60 | C:98 | 92.0 | 0.4 | -109.4 | 164.3 | 48.0 | 0.209 | 0.191 |
D:O60885:0.191 |
WEP HOH |
2.813 5.666 |
OH O |
O16 O |
||
| 7cjb | 1 | P40337 | 100.0 | 8e-116 |
X-RAY |
2021-07-14 | TYR | A:48 | A:98 | 90.0 | 0.391 | -106.5 | 160.1 | 30.0 | 0.13 | 0.261 |
D:Q13546:0.261 |
||||||
| TYR | E:48 | E:98 | 88.0 | 0.383 | -107.5 | 160.0 | NA | NA | NA | ||||||||||||||
| TYR | I:48 | I:98 | 93.0 | 0.404 | -107.3 | 161.3 | NA | NA | NA | ||||||||||||||
| TYR | M:48 | M:98 | 90.0 | 0.391 | -106.3 | 160.7 | NA | NA | NA | ||||||||||||||
| 6zhc | 1 | P40337 | 100.0 | 4e-113 |
X-RAY |
2020-08-05 | TYR | A:40 | AAA:98 | 103.0 | 0.448 | -118.5 | 167.0 | 103.0 | 0.448 | 0.0 |
QL8 IOD HOH |
2.680 7.465 2.800 |
OH CE2 OH |
O16 I O |
|||
| 7pi4 | 1 | P40337 | 100.0 | 4e-113 |
X-RAY |
2021-09-29 | TYR | A:40 | AAA:98 | 105.0 | 0.457 | -109.0 | 171.6 | 79.0 | 0.343 | 0.114 |
D:Q05397:0.113 |
7QB PEG EDO EDO EDO PEG HOH |
2.708 9.948 3.796 5.743 7.733 6.824 2.808 |
OH CE2 OH OH O OH O |
O5 C3 C2 O2 O2 O1 O |
||
| 6fmi | 3 | P40337 | 99.34 | 1e-109 |
X-RAY |
2018-04-11 | TYR | C:47 | C:98 | 20.0 | 0.087 | -122.9 | 173.1 | 20.0 | 0.087 | 0.0 |
DV2 HOH |
2.907 7.393 |
OH CE2 |
SAG O |
|||
| TYR | F:47 | F:98 | 18.0 | 0.078 | -123.5 | 169.5 | NA | NA | NA | ||||||||||||||
| 6fmj | 3 | P40337 | 99.34 | 1e-109 |
X-RAY |
2018-04-11 | TYR | C:47 | C:98 | 20.0 | 0.087 | -116.7 | 169.5 | 20.0 | 0.087 | 0.0 |
DV5 HOH |
2.537 3.105 |
OH O |
O O |
|||
| TYR | F:47 | F:98 | 22.0 | 0.096 | -109.6 | 170.2 | NA | NA | NA | ||||||||||||||
| TYR | I:47 | I:98 | 25.0 | 0.109 | -107.9 | 170.9 | NA | NA | NA | ||||||||||||||
| TYR | L:47 | L:98 | 23.0 | 0.1 | -117.8 | 166.8 | NA | NA | NA | ||||||||||||||
| 6fmk | 3 | P40337 | 99.34 | 1e-109 |
X-RAY |
2018-04-11 | TYR | C:47 | C:98 | 83.0 | 0.361 | -119.0 | 167.8 | 83.0 | 0.361 | 0.0 |
DV8 HOH |
2.845 7.378 |
OH CE2 |
SAF O |
|||
| TYR | F:47 | F:98 | 82.0 | 0.357 | -116.1 | 168.6 | NA | NA | NA | ||||||||||||||
| TYR | I:47 | I:98 | 88.0 | 0.383 | -120.8 | 173.1 | NA | NA | NA | ||||||||||||||
| TYR | L:47 | L:98 | 88.0 | 0.383 | -117.4 | 173.1 | NA | NA | NA | ||||||||||||||
| 6hr2 | 2 | P40337 | 100.0 | 3e-108 |
X-RAY |
2019-06-12 | TYR | B:38 | B:98 | 100.0 | 0.435 | -117.2 | 168.8 | 100.0 | 0.435 | 0.0 |
FWZ DMS HOH |
1.876 6.030 2.894 |
HH HE2 O |
O16 O O |
|||
| TYR | F:38 | F:98 | 100.0 | 0.435 | -117.5 | 169.1 | NA | NA | NA | ||||||||||||||
| 6r6h | 12 | P40337 | 100.0 | 3e-107 |
EM |
2019-08-28 | TYR | L:39 | V:98 | 46.0 | 0.2 | -137.4 | 173.7 | 46.0 | 0.2 | 0.0 | |||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p40337-f1 | 1 | P40337 | 100.0 | 2e-156 | TYR | A:98 | A:98 | 84.0 | 0.365 | -113.0 | 163.1 | ||