Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr3 | 10191512 | . | C | A | CCDS2597.1:NM_000551.3:c.505Cta>Ata_NP_000542.1:p.169L>I | Homo sapiens von Hippel-Lindau tumor suppressor (VHL), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 4wqo | 1 | P40337 | 100.0 | 4e-156 |
X-RAY |
2015-03-04 | LEU | A:189 | A:169 | 134.0 | 0.788 | H | -107.9 | -24.2 | 55.0 | 0.324 | 0.464 |
B:Q15370:0.329 C:Q15369:0.212 |
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| 7q2j | 3 | P40337 | 94.25 | 1e-118 |
X-RAY |
2021-11-24 | LEU | C:153 | C:169 | 84.0 | NA | H | -93.4 | -29.9 | 40.0 | NA | NA |
B:Q15369:NA A:Q15370:NA |
|||||
| 4b9k | 3 | P40337 | 95.32 | 3e-118 |
X-RAY |
2012-10-24 | LEU | C:127 | C:169 | 134.0 | 0.788 | H | -107.1 | -24.2 | 50.0 | 0.294 | 0.494 |
B:Q15369:0.247 A:Q15370:0.312 |
HOH |
4.201 |
O |
O |
|
| LEU | F:127 | F:169 | 141.0 | 0.829 | H | -108.2 | -24.0 | NA | NA | NA | |||||||||||||
| LEU | I:127 | I:169 | 142.0 | 0.835 | H | -107.4 | -23.7 | NA | NA | NA | |||||||||||||
| LEU | L:127 | L:169 | 136.0 | 0.8 | H | -107.4 | -23.5 | NA | NA | NA | |||||||||||||
| 1lqb | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2002-07-03 | LEU | C:118 | C:169 | 143.0 | 0.841 | H | -112.1 | -32.1 | 59.0 | 0.347 | 0.494 |
B:Q15369:0.212 A:Q15370:0.353 |
HOH |
4.085 |
O |
O |
|
| 3ztd | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2012-07-25 | LEU | C:118 | C:169 | 132.0 | 0.776 | H | -107.3 | -0.4 | 60.0 | 0.353 | 0.423 |
B:Q15369:0.224 A:Q15370:0.218 |
HOH |
4.693 |
CD1 |
O |
|
| LEU | F:118 | F:169 | 135.0 | 0.794 | T | -99.7 | -12.7 | NA | NA | NA | |||||||||||||
| LEU | I:118 | I:169 | 129.0 | 0.759 | H | -107.1 | -35.6 | NA | NA | NA | |||||||||||||
| LEU | L:118 | L:169 | 126.0 | 0.741 | H | -119.9 | -15.4 | NA | NA | NA | |||||||||||||
| 4b95 | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2012-10-24 | LEU | C:118 | C:169 | 137.0 | 0.806 | H | -108.7 | -23.7 | 63.0 | 0.371 | 0.435 |
B:Q15369:0.229 A:Q15370:0.241 |
HOH |
4.812 |
N |
O |
|
| LEU | F:118 | F:169 | 141.0 | 0.829 | H | -108.9 | -27.0 | NA | NA | NA | |||||||||||||
| LEU | I:118 | I:169 | 139.0 | 0.818 | H | -110.6 | -18.2 | NA | NA | NA | |||||||||||||
| LEU | L:118 | L:169 | 135.0 | 0.794 | H | -109.5 | -20.2 | NA | NA | NA | |||||||||||||
| 4bks | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2013-11-27 | LEU | C:118 | C:169 | 136.0 | 0.8 | H | -106.5 | -24.1 | 57.0 | 0.335 | 0.465 |
B:Q15369:0.235 A:Q15370:0.282 |
ACT HOH |
7.588 6.112 |
N CD1 |
O O |
|
| LEU | F:118 | F:169 | 142.0 | 0.835 | H | -105.1 | -25.7 | NA | NA | NA | |||||||||||||
| LEU | I:118 | I:169 | 140.0 | 0.824 | H | -106.5 | -26.2 | NA | NA | NA | |||||||||||||
| LEU | L:118 | L:169 | 134.0 | 0.788 | H | -105.7 | -24.4 | NA | NA | NA | |||||||||||||
| 4bkt | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2013-11-27 | LEU | C:118 | C:169 | 137.0 | 0.806 | H | -104.3 | -26.8 | 54.0 | 0.318 | 0.488 |
B:Q15369:0.235 A:Q15370:0.312 |
HOH |
4.725 |
C |
O |
|
| LEU | F:118 | F:169 | 141.0 | 0.829 | H | -103.5 | -27.0 | NA | NA | NA | |||||||||||||
| LEU | I:118 | I:169 | 142.0 | 0.835 | H | -103.5 | -25.8 | NA | NA | NA | |||||||||||||
| LEU | L:118 | L:169 | 135.0 | 0.794 | H | -104.2 | -25.0 | NA | NA | NA | |||||||||||||
| 4w9c | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2014-09-10 | LEU | C:118 | C:169 | 136.0 | 0.8 | H | -107.9 | -25.9 | 60.0 | 0.353 | 0.447 |
B:Q15369:0.229 A:Q15370:0.294 |
HOH |
5.790 |
N |
O |
|
| LEU | F:118 | F:169 | 136.0 | 0.8 | H | -109.0 | -13.0 | NA | NA | NA | |||||||||||||
| LEU | I:118 | I:169 | 140.0 | 0.824 | H | -103.8 | -22.9 | NA | NA | NA | |||||||||||||
| LEU | L:118 | L:169 | 135.0 | 0.794 | H | -100.8 | -19.5 | NA | NA | NA | |||||||||||||
| 4w9d | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2014-09-10 | LEU | C:118 | C:169 | 134.0 | 0.788 | T | -112.3 | -18.6 | 57.0 | 0.335 | 0.453 |
B:Q15369:0.229 A:Q15370:0.294 |
HOH |
5.855 |
N |
O |
|
| LEU | F:118 | F:169 | 132.0 | 0.776 | H | -106.1 | -18.8 | NA | NA | NA | |||||||||||||
| LEU | I:118 | I:169 | 140.0 | 0.824 | H | -97.8 | -21.4 | NA | NA | NA | |||||||||||||
| LEU | L:118 | L:169 | 137.0 | 0.806 | H | -114.1 | -22.4 | NA | NA | NA | |||||||||||||
| 4w9e | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2014-09-10 | LEU | C:118 | C:169 | 136.0 | 0.8 | H | -104.4 | -27.5 | 57.0 | 0.335 | 0.465 |
B:Q15369:0.235 A:Q15370:0.306 |
HOH |
4.502 |
N |
O |
|
| LEU | F:118 | F:169 | 137.0 | 0.806 | H | -85.3 | -31.7 | NA | NA | NA | |||||||||||||
| LEU | I:118 | I:169 | 137.0 | 0.806 | H | -92.9 | -22.6 | NA | NA | NA | |||||||||||||
| LEU | L:118 | L:169 | 133.0 | 0.782 | H | -94.3 | -8.5 | NA | NA | NA | |||||||||||||
| 4w9f | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2014-09-10 | LEU | C:118 | C:169 | 135.0 | 0.794 | H | -106.9 | -18.0 | 53.0 | 0.312 | 0.482 |
B:Q15369:0.229 A:Q15370:0.294 |
HOH |
4.314 |
C |
O |
|
| LEU | F:118 | F:169 | 138.0 | 0.812 | H | -98.9 | -25.9 | NA | NA | NA | |||||||||||||
| LEU | I:118 | I:169 | 133.0 | 0.782 | H | -103.5 | -23.5 | NA | NA | NA | |||||||||||||
| LEU | L:118 | L:169 | 136.0 | 0.8 | H | -107.3 | -16.2 | NA | NA | NA | |||||||||||||
| 4w9g | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2014-09-10 | LEU | C:118 | C:169 | 139.0 | 0.818 | H | -102.1 | -33.3 | 64.0 | 0.376 | 0.442 |
B:Q15369:0.235 A:Q15370:0.282 |
HOH |
6.351 |
CD1 |
O |
|
| LEU | F:118 | F:169 | 138.0 | 0.812 | H | -94.3 | -46.0 | NA | NA | NA | |||||||||||||
| LEU | I:118 | I:169 | 143.0 | 0.841 | H | -95.2 | -21.0 | NA | NA | NA | |||||||||||||
| LEU | L:118 | L:169 | 135.0 | 0.794 | H | -103.0 | -21.1 | NA | NA | NA | |||||||||||||
| 4w9h | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2014-09-10 | LEU | C:118 | C:169 | 136.0 | 0.8 | H | -105.3 | -23.3 | 55.0 | 0.324 | 0.476 |
B:Q15369:0.247 A:Q15370:0.306 |
HOH |
4.473 |
C |
O |
|
| LEU | F:118 | F:169 | 137.0 | 0.806 | H | -103.4 | -20.9 | NA | NA | NA | |||||||||||||
| LEU | I:118 | I:169 | 139.0 | 0.818 | H | -104.2 | -22.3 | NA | NA | NA | |||||||||||||
| LEU | L:118 | L:169 | 138.0 | 0.812 | H | -98.6 | -29.2 | NA | NA | NA | |||||||||||||
| 4w9i | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2014-09-10 | LEU | C:118 | C:169 | 136.0 | 0.8 | H | -110.6 | -19.1 | 55.0 | 0.324 | 0.476 |
B:Q15369:0.229 A:Q15370:0.329 |
HOH |
5.658 |
N |
O |
|
| LEU | F:118 | F:169 | 137.0 | 0.806 | H | -94.7 | -41.6 | NA | NA | NA | |||||||||||||
| LEU | I:118 | I:169 | 138.0 | 0.812 | H | -97.1 | -30.3 | NA | NA | NA | |||||||||||||
| LEU | L:118 | L:169 | 134.0 | 0.788 | H | -113.9 | -13.1 | NA | NA | NA | |||||||||||||
| 4w9j | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2014-09-10 | LEU | C:118 | C:169 | 137.0 | 0.806 | H | -108.0 | -22.6 | 58.0 | 0.341 | 0.465 |
B:Q15369:0.229 A:Q15370:0.306 |
HOH |
4.377 |
O |
O |
|
| LEU | F:118 | F:169 | 136.0 | 0.8 | H | -101.0 | -30.0 | NA | NA | NA | |||||||||||||
| LEU | I:118 | I:169 | 141.0 | 0.829 | H | -97.4 | -28.7 | NA | NA | NA | |||||||||||||
| LEU | L:118 | L:169 | 138.0 | 0.812 | T | -117.0 | -31.5 | NA | NA | NA | |||||||||||||
| 4w9k | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2014-09-10 | LEU | C:118 | C:169 | 137.0 | 0.806 | H | -106.6 | -25.4 | 58.0 | 0.341 | 0.465 |
B:Q15369:0.235 A:Q15370:0.306 |
HOH |
5.705 |
N |
O |
|
| LEU | F:118 | F:169 | 135.0 | 0.794 | H | -103.6 | -47.4 | NA | NA | NA | |||||||||||||
| LEU | I:118 | I:169 | 139.0 | 0.818 | H | -107.9 | -15.4 | NA | NA | NA | |||||||||||||
| LEU | L:118 | L:169 | 137.0 | 0.806 | T | -132.2 | -10.1 | NA | NA | NA | |||||||||||||
| 4w9l | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2014-09-10 | LEU | C:118 | C:169 | 135.0 | 0.794 | H | -106.6 | -26.1 | 58.0 | 0.341 | 0.453 |
B:Q15369:0.235 A:Q15370:0.294 |
HOH |
5.756 |
N |
O |
|
| LEU | F:118 | F:169 | 136.0 | 0.8 | H | -96.7 | -43.8 | NA | NA | NA | |||||||||||||
| LEU | I:118 | I:169 | 137.0 | 0.806 | H | -105.4 | -21.5 | NA | NA | NA | |||||||||||||
| LEU | L:118 | L:169 | 136.0 | 0.8 | H | -113.0 | -28.8 | NA | NA | NA | |||||||||||||
| 5lli | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2016-11-09 | LEU | C:118 | C:169 | 133.0 | 0.782 | T | -116.8 | -12.1 | 56.0 | 0.329 | 0.453 |
B:Q15369:0.212 A:Q15370:0.306 |
HOH |
4.536 |
O |
O |
|
| LEU | F:118 | F:169 | 138.0 | 0.812 | H | -82.4 | -39.8 | NA | NA | NA | |||||||||||||
| LEU | I:118 | I:169 | 135.0 | 0.794 | H | -95.5 | -26.8 | NA | NA | NA | |||||||||||||
| LEU | L:118 | L:169 | 133.0 | 0.782 | H | -110.8 | -22.2 | NA | NA | NA | |||||||||||||
| 5nvv | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2017-09-20 | LEU | C:118 | C:169 | 136.0 | 0.8 | H | -108.9 | -17.1 | 50.0 | 0.294 | 0.506 |
B:Q15369:0.235 A:Q15370:0.341 |
HOH |
4.443 |
O |
O |
|
| LEU | F:118 | F:169 | 132.0 | 0.776 | H | -103.6 | -25.1 | NA | NA | NA | |||||||||||||
| LEU | I:118 | I:169 | 135.0 | 0.794 | H | -101.1 | -22.6 | NA | NA | NA | |||||||||||||
| LEU | L:118 | L:169 | 132.0 | 0.776 | T | -118.3 | -27.4 | NA | NA | NA | |||||||||||||
| 5nvw | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2017-09-20 | LEU | C:118 | C:169 | 135.0 | 0.794 | H | -111.5 | -11.2 | 52.0 | 0.306 | 0.488 |
B:Q15369:0.229 A:Q15370:0.335 |
HOH |
4.366 |
O |
O |
|
| LEU | F:118 | F:169 | 136.0 | 0.8 | H | -111.3 | -23.5 | NA | NA | NA | |||||||||||||
| LEU | I:118 | I:169 | 136.0 | 0.8 | H | -106.2 | -24.9 | NA | NA | NA | |||||||||||||
| LEU | L:118 | L:169 | 137.0 | 0.806 | T | -116.2 | -22.4 | NA | NA | NA | |||||||||||||
| 5nvx | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2017-09-20 | LEU | C:118 | C:169 | 135.0 | 0.794 | H | -113.1 | -13.7 | 52.0 | 0.306 | 0.488 |
B:Q15369:0.229 A:Q15370:0.329 |
HOH |
4.317 |
O |
O |
|
| LEU | F:118 | F:169 | 138.0 | 0.812 | H | -95.0 | -29.2 | NA | NA | NA | |||||||||||||
| LEU | I:118 | I:169 | 136.0 | 0.8 | H | -95.9 | -25.3 | NA | NA | NA | |||||||||||||
| LEU | L:118 | L:169 | 133.0 | 0.782 | T | -115.2 | -16.2 | NA | NA | NA | |||||||||||||
| 5nvy | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2017-09-20 | LEU | C:118 | C:169 | 139.0 | 0.818 | H | -106.1 | -26.4 | 56.0 | 0.329 | 0.489 |
B:Q15369:0.247 A:Q15370:0.324 |
HOH |
6.086 |
CD1 |
O |
|
| LEU | F:118 | F:169 | 132.0 | 0.776 | H | -88.5 | -55.0 | NA | NA | NA | |||||||||||||
| LEU | I:118 | I:169 | 137.0 | 0.806 | H | -72.6 | -21.5 | NA | NA | NA | |||||||||||||
| LEU | L:118 | L:169 | 139.0 | 0.818 | H | -98.7 | -44.5 | NA | NA | NA | |||||||||||||
| 5nvz | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2017-09-20 | LEU | C:118 | C:169 | 134.0 | 0.788 | T | -115.0 | -24.5 | 55.0 | 0.324 | 0.464 |
B:Q15369:0.218 A:Q15370:0.312 |
HOH |
6.140 |
CD1 |
O |
|
| LEU | F:118 | F:169 | 133.0 | 0.782 | H | -101.2 | -60.9 | NA | NA | NA | |||||||||||||
| LEU | I:118 | I:169 | 138.0 | 0.812 | H | -90.9 | -21.7 | NA | NA | NA | |||||||||||||
| LEU | L:118 | L:169 | 136.0 | 0.8 | H | -103.9 | -24.1 | NA | NA | NA | |||||||||||||
| 5nw0 | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2017-09-20 | LEU | C:118 | C:169 | 135.0 | 0.794 | T | -113.0 | -19.3 | 54.0 | 0.318 | 0.476 |
B:Q15369:0.224 A:Q15370:0.324 |
HOH |
4.410 |
O |
O |
|
| LEU | F:118 | F:169 | 136.0 | 0.8 | H | -106.1 | -34.7 | NA | NA | NA | |||||||||||||
| LEU | I:118 | I:169 | 138.0 | 0.812 | H | -100.4 | -21.2 | NA | NA | NA | |||||||||||||
| LEU | L:118 | L:169 | 135.0 | 0.794 | T | -117.8 | -29.2 | NA | NA | NA | |||||||||||||
| 5nw1 | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2017-09-20 | LEU | C:118 | C:169 | 135.0 | 0.794 | H | -108.0 | -20.4 | 55.0 | 0.324 | 0.47 |
B:Q15369:0.224 A:Q15370:0.318 |
HOH |
4.413 |
O |
O |
|
| LEU | F:118 | F:169 | 137.0 | 0.806 | H | -105.3 | -39.3 | NA | NA | NA | |||||||||||||
| LEU | I:118 | I:169 | 137.0 | 0.806 | T | -112.9 | -31.1 | NA | NA | NA | |||||||||||||
| LEU | L:118 | L:169 | 134.0 | 0.788 | T | -112.3 | -15.8 | NA | NA | NA | |||||||||||||
| 5nw2 | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2017-09-20 | LEU | C:118 | C:169 | 135.0 | 0.794 | H | -110.3 | -20.5 | 55.0 | 0.324 | 0.47 |
B:Q15369:0.224 A:Q15370:0.318 |
HOH |
4.491 |
O |
O |
|
| LEU | F:118 | F:169 | 136.0 | 0.8 | H | -101.9 | -29.7 | NA | NA | NA | |||||||||||||
| LEU | I:118 | I:169 | 137.0 | 0.806 | T | -112.8 | -36.6 | NA | NA | NA | |||||||||||||
| LEU | L:118 | L:169 | 135.0 | 0.794 | T | -117.0 | -12.3 | NA | NA | NA | |||||||||||||
| 5t35 | 4 | P40337 | 99.38 | 4e-117 |
X-RAY |
2017-03-08 | LEU | D:118 | D:169 | 138.0 | 0.812 | H | -113.6 | -9.3 | 55.0 | 0.324 | 0.488 |
B:Q15370:0.306 C:Q15369:0.235 |
HOH |
4.363 |
O |
O |
|
| LEU | H:118 | H:169 | 139.0 | 0.818 | H | -113.6 | -9.0 | NA | NA | NA | |||||||||||||
| 6bvb | 1 | P40337 | 99.38 | 4e-117 |
X-RAY |
2018-08-01 | LEU | A:118 | V:169 | 138.0 | 0.812 | H | -100.7 | -20.4 | 51.0 | 0.3 | 0.512 |
B:Q15370:0.359 C:Q15369:0.247 |
HOH |
4.211 |
O |
O |
|
| 6gfy | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2018-07-11 | LEU | C:118 | C:169 | 134.0 | 0.788 | H | -106.2 | -29.8 | 53.0 | 0.312 | 0.476 |
B:Q15369:0.224 A:Q15370:0.324 |
HOH |
5.836 |
N |
O |
|
| LEU | F:118 | F:169 | 131.0 | 0.771 | H | -78.9 | -68.1 | NA | NA | NA | |||||||||||||
| LEU | I:118 | I:169 | 135.0 | 0.794 | H | -92.5 | -35.9 | NA | NA | NA | |||||||||||||
| LEU | L:118 | L:169 | 135.0 | 0.794 | T | -111.1 | -36.7 | NA | NA | NA | |||||||||||||
| 6gfz | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2018-07-11 | LEU | C:118 | C:169 | 135.0 | 0.794 | H | -109.8 | -17.4 | 51.0 | 0.3 | 0.494 |
B:Q15369:0.229 A:Q15370:0.341 |
HOH |
3.561 |
CD2 |
O |
|
| LEU | F:118 | F:169 | 133.0 | 0.782 | H | -93.5 | -26.5 | NA | NA | NA | |||||||||||||
| LEU | I:118 | I:169 | 137.0 | 0.806 | H | -93.8 | -30.9 | NA | NA | NA | |||||||||||||
| LEU | L:118 | L:169 | 136.0 | 0.8 | T | -126.4 | -21.4 | NA | NA | NA | |||||||||||||
| 6gmn | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2018-08-08 | LEU | C:118 | C:169 | 135.0 | 0.794 | H | -108.8 | -23.3 | 51.0 | 0.3 | 0.494 |
B:Q15369:0.229 A:Q15370:0.3 |
ACT HOH |
7.651 4.859 |
N N |
O O |
|
| LEU | F:118 | F:169 | 139.0 | 0.818 | H | -105.1 | -21.6 | NA | NA | NA | |||||||||||||
| LEU | L:118 | L:169 | 133.0 | 0.782 | H | -106.0 | -20.7 | NA | NA | NA | |||||||||||||
| 6gmn | 5 | P40337 | 99.38 | 4e-117 |
X-RAY |
2018-08-08 | LEU | I:118 | I:169 | 136.0 | 0.8 | H | -106.6 | -23.0 | NA | NA | NA | ||||||
| 6gmq | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2018-08-22 | LEU | C:118 | C:169 | 138.0 | 0.812 | T | -107.9 | -25.8 | 58.0 | 0.341 | 0.471 |
A:Q15370:0.306 B:Q15369:0.218 |
HOH |
4.273 |
C |
O |
|
| LEU | F:118 | F:169 | 123.0 | 0.724 | H | -108.6 | -23.2 | NA | NA | NA | |||||||||||||
| LEU | I:118 | I:169 | 134.0 | 0.788 | H | -110.0 | -24.7 | NA | NA | NA | |||||||||||||
| LEU | L:118 | L:169 | 136.0 | 0.8 | T | -112.7 | -24.0 | NA | NA | NA | |||||||||||||
| 6gmx | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2018-08-08 | LEU | C:118 | C:169 | 136.0 | 0.8 | H | -108.6 | -23.0 | 57.0 | 0.335 | 0.465 |
B:Q15369:0.229 A:Q15370:0.276 |
HOH |
5.501 |
N |
O |
|
| LEU | F:118 | F:169 | 134.0 | 0.788 | H | -102.7 | -27.1 | NA | NA | NA | |||||||||||||
| LEU | I:118 | I:169 | 139.0 | 0.818 | H | -107.3 | -22.3 | NA | NA | NA | |||||||||||||
| LEU | L:118 | L:169 | 133.0 | 0.782 | H | -108.0 | -25.5 | NA | NA | NA | |||||||||||||
| 6hax | 2 | P40337 | 99.38 | 4e-117 |
X-RAY |
2019-06-12 | LEU | B:118 | B:169 | 138.0 | 0.812 | H | -104.5 | -27.1 | 52.0 | 0.306 | 0.506 |
D:Q15370:0.335 C:Q15369:0.247 |
EDO HOH |
7.793 4.465 |
N O |
O1 O |
|
| LEU | F:118 | F:169 | 139.0 | 0.818 | H | -104.7 | -27.6 | NA | NA | NA | |||||||||||||
| 6hay | 2 | P40337 | 99.38 | 4e-117 |
X-RAY |
2019-06-12 | LEU | B:118 | B:169 | 136.0 | 0.8 | H | -107.7 | -27.1 | 51.0 | 0.3 | 0.5 |
D:Q15370:0.318 C:Q15369:0.259 |
EDO HOH |
7.886 3.350 |
N O |
O1 O |
|
| LEU | F:118 | F:169 | 135.0 | 0.794 | H | -108.5 | -21.3 | NA | NA | NA | |||||||||||||
| 6sis | 4 | P40337 | 99.38 | 4e-117 |
X-RAY |
2019-12-04 | LEU | D:118 | D:169 | 136.0 | 0.8 | H | -99.0 | -14.7 | 55.0 | 0.324 | 0.476 |
B:Q15370:0.324 C:Q15369:0.229 |
HOH |
8.404 |
CG |
O |
|
| LEU | H:118 | H:169 | 138.0 | 0.812 | H | -99.5 | -14.2 | NA | NA | NA | |||||||||||||
| 7jto | 4 | P40337 | 99.38 | 4e-117 |
X-RAY |
2021-10-06 | LEU | D:118 | L:169 | 133.0 | 0.782 | H | -95.7 | -20.8 | 54.0 | 0.318 | 0.464 |
B:Q15370:0.282 C:Q15369:0.247 |
NA HOH |
8.367 2.439 |
N O |
NA O |
|
| 7jtp | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2021-10-06 | LEU | C:118 | L:169 | 141.0 | 0.829 | T | -112.8 | -25.9 | 56.0 | 0.329 | 0.5 |
B:Q15369:0.253 A:Q15370:0.288 |
HOH |
5.652 |
N |
O |
|
| 3zrc | 3 | P40337 | 98.77 | 4e-117 |
X-RAY |
2012-03-07 | LEU | C:119 | C:169 | 82.0 | NA | T | -109.1 | -19.4 | 76.0 | NA | NA |
B:Q15369:NA |
|||||
| LEU | F:119 | F:169 | 145.0 | 0.853 | T | -122.5 | -26.0 | NA | NA | NA | |||||||||||||
| LEU | I:119 | I:169 | 139.0 | 0.818 | H | -95.1 | -37.8 | NA | NA | NA | |||||||||||||
| LEU | L:119 | L:169 | 139.0 | 0.818 | T | -111.2 | -25.8 | NA | NA | NA | |||||||||||||
| 3zrf | 3 | P40337 | 98.77 | 4e-117 |
X-RAY |
2012-03-07 | LEU | C:119 | C:169 | 87.0 | NA | T | -122.2 | -16.1 | 40.0 | NA | NA |
B:Q15369:NA A:Q15370:NA |
HOH |
6.368 |
N |
O |
|
| LEU | F:119 | F:169 | 133.0 | 0.782 | T | -132.7 | -10.3 | NA | NA | NA | |||||||||||||
| LEU | I:119 | I:169 | 140.0 | 0.824 | H | -107.0 | -21.3 | NA | NA | NA | |||||||||||||
| LEU | L:119 | L:169 | 127.0 | 0.747 | H | -105.5 | -11.5 | NA | NA | NA | |||||||||||||
| 3ztc | 3 | P40337 | 98.77 | 4e-117 |
X-RAY |
2012-07-25 | LEU | C:119 | C:169 | 140.0 | 0.824 | T | -117.5 | -39.5 | 72.0 | 0.424 | 0.4 |
B:Q15369:0.206 A:Q15370:0.188 |
HOH |
4.530 |
CD1 |
O |
|
| LEU | F:119 | F:169 | 128.0 | 0.753 | T | -125.1 | -31.3 | NA | NA | NA | |||||||||||||
| LEU | I:119 | I:169 | 140.0 | 0.824 | H | -96.5 | -25.9 | NA | NA | NA | |||||||||||||
| LEU | L:119 | L:169 | 127.0 | 0.747 | H | -105.4 | -30.4 | NA | NA | NA | |||||||||||||
| 3zun | 3 | P40337 | 98.77 | 4e-117 |
X-RAY |
2012-07-25 | LEU | C:119 | C:169 | 80.0 | NA | T | -113.3 | -9.8 | 42.0 | NA | NA |
B:Q15369:NA A:Q15370:NA |
HOH |
6.602 |
N |
O |
|
| LEU | F:119 | F:169 | 138.0 | 0.812 | H | -107.8 | -39.1 | NA | NA | NA | |||||||||||||
| LEU | I:119 | I:169 | 140.0 | 0.824 | H | -110.0 | -20.8 | NA | NA | NA | |||||||||||||
| LEU | L:119 | L:169 | 134.0 | 0.788 | T | -108.9 | -23.5 | NA | NA | NA | |||||||||||||
| 4ajy | 4 | P40337 | 98.77 | 4e-117 |
X-RAY |
2012-11-14 | LEU | D:119 | V:169 | 135.0 | 0.794 | H | -106.1 | -24.2 | 46.0 | 0.271 | 0.523 |
A:Q15370:0.382 B:Q15369:0.218 |
GOL HOH |
7.208 4.102 |
N O |
C3 O |
|
| 4awj | 3 | P40337 | 98.77 | 4e-117 |
X-RAY |
2012-11-14 | LEU | C:119 | C:169 | 137.0 | 0.806 | T | -112.6 | -25.9 | 62.0 | 0.365 | 0.441 |
B:Q15369:0.212 A:Q15370:0.265 |
ACT HOH |
7.471 3.956 |
N CD2 |
OXT O |
|
| LEU | F:119 | F:169 | 138.0 | 0.812 | T | -123.1 | -43.1 | NA | NA | NA | |||||||||||||
| LEU | I:119 | I:169 | 142.0 | 0.835 | H | -106.3 | -37.5 | NA | NA | NA | |||||||||||||
| LEU | L:119 | L:169 | 140.0 | 0.824 | H | -107.3 | -21.4 | NA | NA | NA | |||||||||||||
| 6gmr | 4 | P40337 | 98.77 | 4e-117 |
X-RAY |
2018-08-08 | LEU | D:119 | V:169 | 137.0 | 0.806 | H | -108.7 | -12.2 | 53.0 | 0.312 | 0.494 |
B:Q15369:0.224 A:Q15370:0.353 |
GOL HOH |
7.259 3.466 |
N CD2 |
C1 O |
|
| 1lm8 | 3 | P40337 | 100.0 | 6e-117 |
X-RAY |
2002-06-12 | LEU | C:116 | V:169 | 132.0 | 0.776 | H | -108.9 | -23.8 | 45.0 | 0.265 | 0.511 |
B:Q15369:0.229 A:Q15370:0.365 |
HOH |
3.203 |
O |
O |
|
| 1vcb | 3 | P40337 | 100.0 | 6e-117 |
X-RAY |
1999-04-21 | LEU | C:116 | C:169 | 139.0 | 0.818 | T | -107.3 | -40.7 | 100.0 | 0.588 | 0.23 |
B:Q15369:0.229 |
HOH |
4.113 |
CD2 |
O |
|
| LEU | F:116 | F:169 | 139.0 | 0.818 | T | -105.0 | -42.0 | NA | NA | NA | |||||||||||||
| LEU | I:116 | I:169 | 139.0 | 0.818 | T | -106.8 | -38.6 | NA | NA | NA | |||||||||||||
| LEU | L:116 | L:169 | 140.0 | 0.824 | T | -107.7 | -40.6 | NA | NA | NA | |||||||||||||
| 5n4w | 2 | P40337 | 100.0 | 6e-117 |
X-RAY |
2017-06-07 | LEU | B:116 | V:169 | 153.0 | 0.9 | S | -131.9 | 16.2 | 130.0 | 0.765 | 0.135 |
E:Q15369:0.135 |
|||||
| 6gfx | 3 | P40337 | 100.0 | 6e-117 |
X-RAY |
2018-07-11 | LEU | C:116 | C:169 | 143.0 | 0.841 | H | -102.6 | -20.5 | 52.0 | 0.306 | 0.535 |
B:Q15369:0.229 A:Q15370:0.394 |
HOH |
2.734 |
O |
O |
|
| 6i7q | 4 | P40337 | 100.0 | 6e-117 |
X-RAY |
2019-11-27 | LEU | D:116 | V:169 | 135.0 | 0.794 | H | -105.1 | -16.2 | 50.0 | 0.294 | 0.5 |
B:Q2KII4:0.253 A:Q15370:0.318 |
GOL HOH |
6.569 3.050 |
HG HD22 |
HO1 O |
|
| 6i7r | 4 | P40337 | 100.0 | 6e-117 |
X-RAY |
2019-11-27 | LEU | D:116 | V:169 | 131.0 | 0.771 | H | -117.5 | -8.4 | 49.0 | 0.288 | 0.483 |
B:Q15369:0.212 A:Q15370:0.341 |
FMT HOH |
7.110 4.360 |
HG N |
O2 O |
|
| 6r7f | 9 | P40337 | 100.0 | 6e-117 |
EM |
2019-08-28 | LEU | I:116 | V:169 | 132.0 | 0.776 | H | -74.2 | -36.2 | 90.0 | 0.529 | 0.247 |
J:Q15370:0.082 K:Q15369:0.165 |
|||||
| 7khh | 3 | P40337 | 100.0 | 6e-116 |
X-RAY |
2021-02-24 | LEU | C:131 | C:169 | 136.0 | 0.8 | H | -107.4 | -24.7 | 52.0 | 0.306 | 0.494 |
A:Q15370:0.335 B:Q15369:0.247 |
HOH |
4.090 |
O |
O |
|
| 7cjb | 1 | P40337 | 100.0 | 8e-116 |
X-RAY |
2021-07-14 | LEU | A:119 | A:169 | 133.0 | 0.782 | H | -102.3 | -20.2 | 39.0 | 0.229 | 0.553 |
C:None:0.224 B:Q15370:0.406 |
|||||
| LEU | E:119 | E:169 | 135.0 | 0.794 | H | -102.3 | -20.0 | NA | NA | NA | |||||||||||||
| LEU | I:119 | I:169 | 137.0 | 0.806 | H | -102.1 | -20.7 | NA | NA | NA | |||||||||||||
| LEU | M:119 | M:169 | 134.0 | 0.788 | H | -101.6 | -21.3 | NA | NA | NA | |||||||||||||
| 6zhc | 1 | P40337 | 100.0 | 4e-113 |
X-RAY |
2020-08-05 | LEU | A:111 | AAA:169 | 135.0 | 0.794 | H | -98.7 | -18.7 | 50.0 | 0.294 | 0.5 |
B:Q15370:0.318 C:Q15369:0.259 |
EDO GOL EDO HOH |
4.041 7.371 8.818 4.173 |
O N CD1 CD1 |
O1 C1 O2 O |
|
| 7pi4 | 1 | P40337 | 100.0 | 4e-113 |
X-RAY |
2021-09-29 | LEU | A:111 | AAA:169 | 135.0 | 0.794 | H | -105.2 | -27.5 | 52.0 | 0.306 | 0.488 |
B:Q15370:0.335 C:Q15369-2:0.241 |
EDO EDO HOH |
4.071 6.866 4.091 |
C N O |
C2 O2 O |
|
| 6fmi | 3 | P40337 | 99.34 | 1e-109 |
X-RAY |
2018-04-11 | LEU | C:118 | C:169 | 142.0 | 0.835 | H | -101.5 | -30.8 | 65.0 | 0.382 | 0.453 |
B:Q15369:0.229 A:Q15370:0.265 |
HOH |
8.399 |
CD2 |
O |
|
| LEU | F:118 | F:169 | 137.0 | 0.806 | H | -76.1 | -52.7 | NA | NA | NA | |||||||||||||
| 6fmj | 3 | P40337 | 99.34 | 1e-109 |
X-RAY |
2018-04-11 | LEU | C:118 | C:169 | 134.0 | 0.788 | H | -105.8 | -38.6 | 54.0 | 0.318 | 0.47 |
B:Q15369:0.235 A:Q15370:0.318 |
HOH |
5.637 |
N |
O |
|
| LEU | F:118 | F:169 | 136.0 | 0.8 | H | -88.0 | -48.8 | NA | NA | NA | |||||||||||||
| LEU | I:118 | I:169 | 135.0 | 0.794 | H | -82.4 | -35.8 | NA | NA | NA | |||||||||||||
| LEU | L:118 | L:169 | 136.0 | 0.8 | H | -102.0 | -33.7 | NA | NA | NA | |||||||||||||
| 6fmk | 3 | P40337 | 99.34 | 1e-109 |
X-RAY |
2018-04-11 | LEU | C:118 | C:169 | 141.0 | 0.829 | H | -96.9 | -43.6 | 55.0 | 0.324 | 0.505 |
B:Q15369:0.253 A:Q15370:0.312 |
HOH |
4.921 |
O |
O |
|
| LEU | F:118 | F:169 | 136.0 | 0.8 | H | -98.3 | -49.9 | NA | NA | NA | |||||||||||||
| LEU | I:118 | I:169 | 133.0 | 0.782 | H | -90.0 | -34.2 | NA | NA | NA | |||||||||||||
| LEU | L:118 | L:169 | 136.0 | 0.8 | H | -100.9 | -46.7 | NA | NA | NA | |||||||||||||
| 6hr2 | 2 | P40337 | 100.0 | 3e-108 |
X-RAY |
2019-06-12 | LEU | B:109 | B:169 | 137.0 | 0.806 | H | -98.0 | -32.9 | 50.0 | 0.294 | 0.512 |
D:Q15370:0.324 C:Q15369:0.253 |
HOH |
4.563 |
HD11 |
O |
|
| LEU | F:109 | F:169 | 137.0 | 0.806 | H | -98.0 | -33.0 | NA | NA | NA | |||||||||||||
| 6r6h | 12 | P40337 | 100.0 | 3e-107 |
EM |
2019-08-28 | LEU | L:110 | V:169 | 126.0 | 0.741 | S | -103.8 | -58.1 | 33.0 | 0.194 | 0.547 |
I:Q15370:0.453 J:None:0.182 |
|||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p40337-f1 | 1 | P40337 | 100.0 | 2e-156 | LEU | A:169 | A:169 | 139.0 | 0.818 | H | -101.4 | -25.5 | |