Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr3 | 10191531 | . | A | C | CCDS2597.1:NM_000551.3:c.524tAc>tCc_NP_000542.1:p.175Y>S | Homo sapiens von Hippel-Lindau tumor suppressor (VHL), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 4wqo | 1 | P40337 | 100.0 | 4e-156 |
X-RAY |
2015-03-04 | TYR | A:195 | A:175 | 4.0 | 0.017 | G | -49.9 | -50.7 | 4.0 | 0.017 | 0.0 | ||||||
| 7q2j | 3 | P40337 | 94.25 | 1e-118 |
X-RAY |
2021-11-24 | TYR | C:159 | C:175 | 2.0 | 0.009 | G | -39.3 | -45.9 | 2.0 | 0.009 | 0.0 | ||||||
| 4b9k | 3 | P40337 | 95.32 | 3e-118 |
X-RAY |
2012-10-24 | TYR | C:133 | C:175 | 18.0 | 0.078 | G | -58.1 | -41.1 | 18.0 | 0.078 | 0.0 |
HOH |
2.644 |
OH |
O |
||
| TYR | F:133 | F:175 | 13.0 | 0.057 | G | -58.0 | -42.1 | NA | NA | NA | |||||||||||||
| TYR | I:133 | I:175 | 2.0 | 0.009 | G | -56.9 | -45.4 | NA | NA | NA | |||||||||||||
| TYR | L:133 | L:175 | 2.0 | 0.009 | G | -57.0 | -44.2 | NA | NA | NA | |||||||||||||
| 1lqb | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2002-07-03 | TYR | C:124 | C:175 | 15.0 | 0.065 | G | -39.7 | -50.8 | 15.0 | 0.065 | 0.0 |
HOH |
2.431 |
OH |
O |
||
| 3ztd | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2012-07-25 | TYR | C:124 | C:175 | 4.0 | 0.017 | G | -63.8 | -46.9 | 4.0 | 0.017 | 0.0 |
HOH |
9.001 |
CD1 |
O |
||
| TYR | F:124 | F:175 | 6.0 | 0.026 | G | -47.0 | -44.8 | NA | NA | NA | |||||||||||||
| TYR | I:124 | I:175 | 4.0 | 0.017 | T | -44.7 | -35.8 | NA | NA | NA | |||||||||||||
| TYR | L:124 | L:175 | 4.0 | 0.017 | G | -48.2 | -40.1 | NA | NA | NA | |||||||||||||
| 4b95 | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2012-10-24 | TYR | C:124 | C:175 | 14.0 | 0.061 | G | -58.2 | -35.2 | 14.0 | 0.061 | 0.0 |
HOH |
5.077 |
OH |
O |
||
| TYR | F:124 | F:175 | 6.0 | 0.026 | G | -50.2 | -49.1 | NA | NA | NA | |||||||||||||
| TYR | I:124 | I:175 | 16.0 | 0.07 | G | -51.4 | -45.6 | NA | NA | NA | |||||||||||||
| TYR | L:124 | L:175 | 10.0 | 0.043 | G | -49.6 | -47.9 | NA | NA | NA | |||||||||||||
| 4bks | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2013-11-27 | TYR | C:124 | C:175 | 4.0 | 0.017 | G | -57.3 | -38.7 | 4.0 | 0.017 | 0.0 |
HOH |
3.774 |
O |
O |
||
| TYR | F:124 | F:175 | 3.0 | 0.013 | G | -56.5 | -42.4 | NA | NA | NA | |||||||||||||
| TYR | I:124 | I:175 | 3.0 | 0.013 | G | -56.3 | -39.0 | NA | NA | NA | |||||||||||||
| TYR | L:124 | L:175 | 4.0 | 0.017 | G | -56.1 | -38.4 | NA | NA | NA | |||||||||||||
| 4bkt | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2013-11-27 | TYR | C:124 | C:175 | 5.0 | 0.022 | G | -58.2 | -39.5 | 5.0 | 0.022 | 0.0 |
HOH |
6.437 |
OH |
O |
||
| TYR | F:124 | F:175 | 5.0 | 0.022 | G | -57.3 | -40.1 | NA | NA | NA | |||||||||||||
| TYR | I:124 | I:175 | 4.0 | 0.017 | G | -57.4 | -39.4 | NA | NA | NA | |||||||||||||
| TYR | L:124 | L:175 | 4.0 | 0.017 | G | -55.5 | -41.2 | NA | NA | NA | |||||||||||||
| 4w9c | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2014-09-10 | TYR | C:124 | C:175 | 3.0 | 0.013 | G | -52.4 | -34.3 | 3.0 | 0.013 | 0.0 |
HOH |
2.552 |
OH |
O |
||
| TYR | F:124 | F:175 | 3.0 | 0.013 | G | -54.3 | -38.5 | NA | NA | NA | |||||||||||||
| TYR | I:124 | I:175 | 2.0 | 0.009 | G | -59.7 | -36.3 | NA | NA | NA | |||||||||||||
| TYR | L:124 | L:175 | 5.0 | 0.022 | G | -58.3 | -39.0 | NA | NA | NA | |||||||||||||
| 4w9d | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2014-09-10 | TYR | C:124 | C:175 | 4.0 | 0.017 | G | -49.8 | -34.7 | 4.0 | 0.017 | 0.0 |
HOH |
2.454 |
OH |
O |
||
| TYR | F:124 | F:175 | 2.0 | 0.009 | G | -53.1 | -38.4 | NA | NA | NA | |||||||||||||
| TYR | I:124 | I:175 | 3.0 | 0.013 | G | -51.4 | -40.4 | NA | NA | NA | |||||||||||||
| TYR | L:124 | L:175 | 2.0 | 0.009 | G | -55.4 | -42.1 | NA | NA | NA | |||||||||||||
| 4w9e | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2014-09-10 | TYR | C:124 | C:175 | 5.0 | 0.022 | G | -56.2 | -38.3 | 5.0 | 0.022 | 0.0 |
HOH |
2.422 |
OH |
O |
||
| TYR | F:124 | F:175 | 6.0 | 0.026 | G | -44.8 | -41.0 | NA | NA | NA | |||||||||||||
| TYR | I:124 | I:175 | 2.0 | 0.009 | G | -57.1 | -33.4 | NA | NA | NA | |||||||||||||
| TYR | L:124 | L:175 | 4.0 | 0.017 | T | -58.0 | -36.8 | NA | NA | NA | |||||||||||||
| 4w9f | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2014-09-10 | TYR | C:124 | C:175 | 13.0 | 0.057 | G | -52.4 | -41.7 | 13.0 | 0.057 | 0.0 |
HOH |
2.425 |
OH |
O |
||
| TYR | F:124 | F:175 | 5.0 | 0.022 | G | -52.4 | -45.6 | NA | NA | NA | |||||||||||||
| TYR | I:124 | I:175 | 3.0 | 0.013 | G | -55.4 | -45.4 | NA | NA | NA | |||||||||||||
| TYR | L:124 | L:175 | 96.0 | 0.417 | -58.0 | 360.0 | NA | NA | NA | ||||||||||||||
| 4w9g | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2014-09-10 | TYR | C:124 | C:175 | 6.0 | 0.026 | T | -61.3 | -41.9 | 6.0 | 0.026 | 0.0 |
HOH |
7.536 |
OH |
O |
||
| TYR | F:124 | F:175 | 6.0 | 0.026 | G | -50.3 | -41.0 | NA | NA | NA | |||||||||||||
| TYR | I:124 | I:175 | 3.0 | 0.013 | G | -51.3 | -38.1 | NA | NA | NA | |||||||||||||
| TYR | L:124 | L:175 | 6.0 | 0.026 | G | -57.0 | -36.6 | NA | NA | NA | |||||||||||||
| 4w9h | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2014-09-10 | TYR | C:124 | C:175 | 4.0 | 0.017 | G | -51.4 | -37.2 | 4.0 | 0.017 | 0.0 |
HOH |
2.473 |
OH |
O |
||
| TYR | F:124 | F:175 | 3.0 | 0.013 | G | -50.1 | -43.6 | NA | NA | NA | |||||||||||||
| TYR | I:124 | I:175 | 3.0 | 0.013 | G | -52.0 | -44.0 | NA | NA | NA | |||||||||||||
| TYR | L:124 | L:175 | 4.0 | 0.017 | G | -49.8 | -42.7 | NA | NA | NA | |||||||||||||
| 4w9i | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2014-09-10 | TYR | C:124 | C:175 | 4.0 | 0.017 | T | -50.3 | -33.6 | 4.0 | 0.017 | 0.0 |
HOH |
2.552 |
OH |
O |
||
| TYR | F:124 | F:175 | 3.0 | 0.013 | G | -51.2 | -45.3 | NA | NA | NA | |||||||||||||
| TYR | I:124 | I:175 | 2.0 | 0.009 | G | -53.8 | -40.2 | NA | NA | NA | |||||||||||||
| TYR | L:124 | L:175 | 3.0 | 0.013 | G | -53.4 | -40.7 | NA | NA | NA | |||||||||||||
| 4w9j | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2014-09-10 | TYR | C:124 | C:175 | 14.0 | 0.061 | G | -51.5 | -41.1 | 14.0 | 0.061 | 0.0 |
HOH |
2.604 |
OH |
O |
||
| TYR | F:124 | F:175 | 5.0 | 0.022 | G | -51.5 | -40.0 | NA | NA | NA | |||||||||||||
| TYR | I:124 | I:175 | 11.0 | 0.048 | G | -51.9 | -40.5 | NA | NA | NA | |||||||||||||
| TYR | L:124 | L:175 | 9.0 | 0.039 | G | -45.2 | -42.6 | NA | NA | NA | |||||||||||||
| 4w9k | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2014-09-10 | TYR | C:124 | C:175 | 7.0 | 0.03 | G | -55.7 | -34.3 | 7.0 | 0.03 | 0.0 |
HOH |
2.583 |
OH |
O |
||
| TYR | F:124 | F:175 | 6.0 | 0.026 | G | -49.0 | -39.2 | NA | NA | NA | |||||||||||||
| TYR | I:124 | I:175 | 3.0 | 0.013 | G | -54.2 | -33.0 | NA | NA | NA | |||||||||||||
| TYR | L:124 | L:175 | 3.0 | 0.013 | G | -50.5 | -47.4 | NA | NA | NA | |||||||||||||
| 4w9l | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2014-09-10 | TYR | C:124 | C:175 | 15.0 | 0.065 | G | -55.5 | -35.3 | 15.0 | 0.065 | 0.0 |
HOH |
2.605 |
OH |
O |
||
| TYR | F:124 | F:175 | 6.0 | 0.026 | G | -53.9 | -37.5 | NA | NA | NA | |||||||||||||
| TYR | I:124 | I:175 | 4.0 | 0.017 | G | -56.8 | -42.9 | NA | NA | NA | |||||||||||||
| TYR | L:124 | L:175 | 8.0 | 0.035 | G | -54.4 | -42.7 | NA | NA | NA | |||||||||||||
| 5lli | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2016-11-09 | TYR | C:124 | C:175 | 10.0 | 0.043 | G | -46.8 | -40.6 | 10.0 | 0.043 | 0.0 |
HOH |
2.601 |
OH |
O |
||
| TYR | F:124 | F:175 | 11.0 | 0.048 | G | -55.2 | -44.4 | NA | NA | NA | |||||||||||||
| TYR | I:124 | I:175 | 5.0 | 0.022 | S | -62.9 | -33.7 | NA | NA | NA | |||||||||||||
| TYR | L:124 | L:175 | 3.0 | 0.013 | G | -45.2 | -48.4 | NA | NA | NA | |||||||||||||
| 5nvv | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2017-09-20 | TYR | C:124 | C:175 | 10.0 | 0.043 | G | -52.3 | -39.9 | 10.0 | 0.043 | 0.0 |
HOH |
2.488 |
OH |
O |
||
| TYR | F:124 | F:175 | 11.0 | 0.048 | G | -54.8 | -43.7 | NA | NA | NA | |||||||||||||
| TYR | I:124 | I:175 | 4.0 | 0.017 | S | -60.1 | -39.1 | NA | NA | NA | |||||||||||||
| TYR | L:124 | L:175 | 2.0 | 0.009 | G | -56.1 | -47.5 | NA | NA | NA | |||||||||||||
| 5nvw | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2017-09-20 | TYR | C:124 | C:175 | 10.0 | 0.043 | G | -51.7 | -39.0 | 10.0 | 0.043 | 0.0 |
HOH |
2.599 |
OH |
O |
||
| TYR | F:124 | F:175 | 10.0 | 0.043 | G | -53.7 | -45.5 | NA | NA | NA | |||||||||||||
| TYR | I:124 | I:175 | 5.0 | 0.022 | G | -57.6 | -39.7 | NA | NA | NA | |||||||||||||
| TYR | L:124 | L:175 | 3.0 | 0.013 | G | -58.7 | -44.1 | NA | NA | NA | |||||||||||||
| 5nvx | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2017-09-20 | TYR | C:124 | C:175 | 10.0 | 0.043 | G | -47.0 | -38.7 | 10.0 | 0.043 | 0.0 |
HOH |
2.594 |
OH |
O |
||
| TYR | F:124 | F:175 | 9.0 | 0.039 | G | -52.8 | -42.0 | NA | NA | NA | |||||||||||||
| TYR | I:124 | I:175 | 5.0 | 0.022 | G | -56.9 | -38.8 | NA | NA | NA | |||||||||||||
| TYR | L:124 | L:175 | 3.0 | 0.013 | S | -57.9 | -50.3 | NA | NA | NA | |||||||||||||
| 5nvy | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2017-09-20 | TYR | C:124 | C:175 | 12.0 | 0.052 | T | -59.5 | -43.7 | 12.0 | 0.052 | 0.0 |
HOH |
2.726 |
OH |
O |
||
| TYR | F:124 | F:175 | 11.0 | 0.048 | G | -55.7 | -43.2 | NA | NA | NA | |||||||||||||
| TYR | I:124 | I:175 | 4.0 | 0.017 | G | -68.9 | -35.6 | NA | NA | NA | |||||||||||||
| TYR | L:124 | L:175 | 3.0 | 0.013 | G | -53.7 | -27.7 | NA | NA | NA | |||||||||||||
| 5nvz | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2017-09-20 | TYR | C:124 | C:175 | 12.0 | 0.052 | G | -43.3 | -31.9 | 12.0 | 0.052 | 0.0 |
HOH |
7.337 |
OH |
O |
||
| TYR | F:124 | F:175 | 11.0 | 0.048 | G | -48.6 | -43.1 | NA | NA | NA | |||||||||||||
| TYR | I:124 | I:175 | 4.0 | 0.017 | G | -54.6 | -36.1 | NA | NA | NA | |||||||||||||
| TYR | L:124 | L:175 | 7.0 | 0.03 | G | -44.7 | -40.8 | NA | NA | NA | |||||||||||||
| 5nw0 | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2017-09-20 | TYR | C:124 | C:175 | 15.0 | 0.065 | G | -54.0 | -34.2 | 15.0 | 0.065 | 0.0 |
HOH |
2.570 |
OH |
O |
||
| TYR | F:124 | F:175 | 14.0 | 0.061 | G | -50.2 | -40.5 | NA | NA | NA | |||||||||||||
| TYR | I:124 | I:175 | 6.0 | 0.026 | G | -55.4 | -41.4 | NA | NA | NA | |||||||||||||
| TYR | L:124 | L:175 | 6.0 | 0.026 | G | -56.2 | -46.1 | NA | NA | NA | |||||||||||||
| 5nw1 | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2017-09-20 | TYR | C:124 | C:175 | 14.0 | 0.061 | G | -54.3 | -37.6 | 14.0 | 0.061 | 0.0 |
HOH |
2.658 |
OH |
O |
||
| TYR | F:124 | F:175 | 11.0 | 0.048 | G | -58.2 | -41.3 | NA | NA | NA | |||||||||||||
| TYR | I:124 | I:175 | 4.0 | 0.017 | G | -50.2 | -52.9 | NA | NA | NA | |||||||||||||
| TYR | L:124 | L:175 | 3.0 | 0.013 | G | -49.8 | -49.4 | NA | NA | NA | |||||||||||||
| 5nw2 | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2017-09-20 | TYR | C:124 | C:175 | 15.0 | 0.065 | G | -53.2 | -35.1 | 15.0 | 0.065 | 0.0 |
HOH |
2.659 |
OH |
O |
||
| TYR | F:124 | F:175 | 12.0 | 0.052 | G | -53.7 | -41.0 | NA | NA | NA | |||||||||||||
| TYR | I:124 | I:175 | 3.0 | 0.013 | G | -49.8 | -48.0 | NA | NA | NA | |||||||||||||
| TYR | L:124 | L:175 | 3.0 | 0.013 | G | -56.8 | -46.1 | NA | NA | NA | |||||||||||||
| 5t35 | 4 | P40337 | 99.38 | 4e-117 |
X-RAY |
2017-03-08 | TYR | D:124 | D:175 | 7.0 | 0.03 | G | -45.5 | -42.6 | 7.0 | 0.03 | 0.0 |
HOH |
6.138 |
N |
O |
||
| TYR | H:124 | H:175 | 7.0 | 0.03 | G | -45.7 | -42.8 | NA | NA | NA | |||||||||||||
| 6bvb | 1 | P40337 | 99.38 | 4e-117 |
X-RAY |
2018-08-01 | TYR | A:124 | V:175 | 4.0 | 0.017 | G | -48.4 | -45.9 | 4.0 | 0.017 | 0.0 |
HOH |
2.526 |
OH |
O |
||
| 6gfy | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2018-07-11 | TYR | C:124 | C:175 | 8.0 | 0.035 | G | -51.2 | -39.2 | 8.0 | 0.035 | 0.0 |
HOH |
2.627 |
OH |
O |
||
| TYR | F:124 | F:175 | 9.0 | 0.039 | G | -52.2 | -44.9 | NA | NA | NA | |||||||||||||
| TYR | I:124 | I:175 | 4.0 | 0.017 | T | -61.5 | -33.8 | NA | NA | NA | |||||||||||||
| TYR | L:124 | L:175 | 5.0 | 0.022 | G | -43.0 | -48.4 | NA | NA | NA | |||||||||||||
| 6gfz | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2018-07-11 | TYR | C:124 | C:175 | 13.0 | 0.057 | G | -52.8 | -46.6 | 13.0 | 0.057 | 0.0 |
HOH |
2.604 |
OH |
O |
||
| TYR | F:124 | F:175 | 12.0 | 0.052 | G | -57.6 | -42.7 | NA | NA | NA | |||||||||||||
| TYR | I:124 | I:175 | 4.0 | 0.017 | G | -52.9 | -43.3 | NA | NA | NA | |||||||||||||
| TYR | L:124 | L:175 | 2.0 | 0.009 | G | -53.6 | -55.0 | NA | NA | NA | |||||||||||||
| 6gmn | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2018-08-08 | TYR | C:124 | C:175 | 15.0 | 0.065 | G | -57.3 | -38.2 | 15.0 | 0.065 | 0.0 |
HOH |
6.313 |
OH |
O |
||
| TYR | F:124 | F:175 | 3.0 | 0.013 | G | -57.6 | -41.3 | NA | NA | NA | |||||||||||||
| TYR | L:124 | L:175 | 4.0 | 0.017 | G | -57.7 | -39.6 | NA | NA | NA | |||||||||||||
| 6gmn | 5 | P40337 | 99.38 | 4e-117 |
X-RAY |
2018-08-08 | TYR | I:124 | I:175 | 3.0 | 0.013 | G | -57.1 | -38.4 | NA | NA | NA | ||||||
| 6gmq | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2018-08-22 | TYR | C:124 | C:175 | 5.0 | 0.022 | G | -47.1 | -45.7 | 5.0 | 0.022 | 0.0 |
HOH |
6.001 |
OH |
O |
||
| TYR | F:124 | F:175 | 12.0 | 0.052 | G | -44.7 | -48.3 | NA | NA | NA | |||||||||||||
| TYR | I:124 | I:175 | 7.0 | 0.03 | G | -46.9 | -45.4 | NA | NA | NA | |||||||||||||
| TYR | L:124 | L:175 | 3.0 | 0.013 | G | -51.5 | -47.4 | NA | NA | NA | |||||||||||||
| 6gmx | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2018-08-08 | TYR | C:124 | C:175 | 9.0 | 0.039 | G | -54.1 | -42.1 | 9.0 | 0.039 | 0.0 |
HOH |
7.018 |
OH |
O |
||
| TYR | F:124 | F:175 | 12.0 | 0.052 | G | -50.8 | -40.9 | NA | NA | NA | |||||||||||||
| TYR | I:124 | I:175 | 3.0 | 0.013 | G | -50.7 | -42.4 | NA | NA | NA | |||||||||||||
| TYR | L:124 | L:175 | 4.0 | 0.017 | G | -55.0 | -42.4 | NA | NA | NA | |||||||||||||
| 6hax | 2 | P40337 | 99.38 | 4e-117 |
X-RAY |
2019-06-12 | TYR | B:124 | B:175 | 3.0 | 0.013 | G | -57.1 | -44.5 | 3.0 | 0.013 | 0.0 |
HOH |
3.528 |
N |
O |
||
| TYR | F:124 | F:175 | 4.0 | 0.017 | G | -57.9 | -43.3 | NA | NA | NA | |||||||||||||
| 6hay | 2 | P40337 | 99.38 | 4e-117 |
X-RAY |
2019-06-12 | TYR | B:124 | B:175 | 2.0 | 0.009 | G | -49.7 | -48.0 | 2.0 | 0.009 | 0.0 |
EDO HOH |
9.690 2.714 |
OH OH |
O1 O |
||
| TYR | F:124 | F:175 | 2.0 | 0.009 | G | -61.0 | -45.9 | NA | NA | NA | |||||||||||||
| 6sis | 4 | P40337 | 99.38 | 4e-117 |
X-RAY |
2019-12-04 | TYR | D:124 | D:175 | 4.0 | 0.017 | G | -65.6 | -33.1 | 4.0 | 0.017 | 0.0 | ||||||
| TYR | H:124 | H:175 | 5.0 | 0.022 | G | -65.7 | -33.3 | NA | NA | NA | |||||||||||||
| 7jto | 4 | P40337 | 99.38 | 4e-117 |
X-RAY |
2021-10-06 | TYR | D:124 | L:175 | 3.0 | 0.013 | G | -50.7 | -47.7 | 3.0 | 0.013 | 0.0 |
HOH |
2.592 |
OH |
O |
||
| 7jtp | 3 | P40337 | 99.38 | 4e-117 |
X-RAY |
2021-10-06 | TYR | C:124 | L:175 | 4.0 | 0.017 | T | -61.2 | -50.4 | 4.0 | 0.017 | 0.0 |
HOH |
2.121 |
OH |
O |
||
| 3zrc | 3 | P40337 | 98.77 | 4e-117 |
X-RAY |
2012-03-07 | TYR | C:125 | C:175 | 21.0 | NA | -98.5 | 20.1 | 21.0 | NA | NA | |||||||
| TYR | F:125 | F:175 | 13.0 | 0.057 | G | -55.6 | -45.5 | NA | NA | NA | |||||||||||||
| TYR | I:125 | I:175 | 4.0 | 0.017 | S | -39.4 | -32.7 | NA | NA | NA | |||||||||||||
| TYR | L:125 | L:175 | 4.0 | 0.017 | T | -66.4 | -13.8 | NA | NA | NA | |||||||||||||
| 3zrf | 3 | P40337 | 98.77 | 4e-117 |
X-RAY |
2012-03-07 | TYR | C:125 | C:175 | 37.0 | NA | G | -71.2 | -25.9 | 37.0 | NA | NA | ||||||
| TYR | F:125 | F:175 | 11.0 | 0.048 | G | -51.7 | -42.2 | NA | NA | NA | |||||||||||||
| TYR | I:125 | I:175 | 2.0 | 0.009 | G | -44.9 | -32.2 | NA | NA | NA | |||||||||||||
| TYR | L:125 | L:175 | 7.0 | 0.03 | G | -52.9 | -39.6 | NA | NA | NA | |||||||||||||
| 3ztc | 3 | P40337 | 98.77 | 4e-117 |
X-RAY |
2012-07-25 | TYR | C:125 | C:175 | 9.0 | 0.039 | G | -61.6 | -47.8 | 9.0 | 0.039 | 0.0 |
HOH |
9.389 |
CD1 |
O |
||
| TYR | F:125 | F:175 | 4.0 | 0.017 | G | -45.6 | -44.0 | NA | NA | NA | |||||||||||||
| TYR | I:125 | I:175 | 5.0 | 0.022 | G | -46.4 | -28.6 | NA | NA | NA | |||||||||||||
| TYR | L:125 | L:175 | 4.0 | 0.017 | G | -57.7 | -42.4 | NA | NA | NA | |||||||||||||
| 3zun | 3 | P40337 | 98.77 | 4e-117 |
X-RAY |
2012-07-25 | TYR | C:125 | C:175 | 5.0 | 0.022 | G | -62.9 | -37.8 | 5.0 | 0.022 | 0.0 |
HOH |
5.766 |
O |
O |
||
| TYR | F:125 | F:175 | 6.0 | 0.026 | G | -61.4 | -45.6 | NA | NA | NA | |||||||||||||
| TYR | I:125 | I:175 | 7.0 | 0.03 | G | -53.3 | -35.9 | NA | NA | NA | |||||||||||||
| TYR | L:125 | L:175 | 4.0 | 0.017 | G | -51.4 | -41.2 | NA | NA | NA | |||||||||||||
| 4ajy | 4 | P40337 | 98.77 | 4e-117 |
X-RAY |
2012-11-14 | TYR | D:125 | V:175 | 15.0 | 0.065 | G | -52.0 | -45.3 | 15.0 | 0.065 | 0.0 |
HOH |
2.624 |
OH |
O |
||
| 4awj | 3 | P40337 | 98.77 | 4e-117 |
X-RAY |
2012-11-14 | TYR | C:125 | C:175 | 7.0 | 0.03 | G | -64.8 | -30.5 | 7.0 | 0.03 | 0.0 |
HOH |
6.062 |
OH |
O |
||
| TYR | F:125 | F:175 | 4.0 | 0.017 | G | -65.3 | -37.0 | NA | NA | NA | |||||||||||||
| TYR | I:125 | I:175 | 6.0 | 0.026 | G | -67.3 | -29.5 | NA | NA | NA | |||||||||||||
| TYR | L:125 | L:175 | 5.0 | 0.022 | G | -58.0 | -45.5 | NA | NA | NA | |||||||||||||
| 6gmr | 4 | P40337 | 98.77 | 4e-117 |
X-RAY |
2018-08-08 | TYR | D:125 | V:175 | 15.0 | 0.065 | G | -52.8 | -46.6 | 15.0 | 0.065 | 0.0 |
HOH |
2.681 |
OH |
O |
||
| 1lm8 | 3 | P40337 | 100.0 | 6e-117 |
X-RAY |
2002-06-12 | TYR | C:122 | V:175 | 18.0 | 0.078 | G | -49.9 | -49.3 | 18.0 | 0.078 | 0.0 |
HOH |
2.872 |
OH |
O |
||
| 1vcb | 3 | P40337 | 100.0 | 6e-117 |
X-RAY |
1999-04-21 | TYR | C:122 | C:175 | 4.0 | 0.017 | G | -58.7 | -41.7 | 4.0 | 0.017 | 0.0 |
HOH |
6.536 |
N |
O |
||
| TYR | F:122 | F:175 | 5.0 | 0.022 | G | -60.2 | -41.1 | NA | NA | NA | |||||||||||||
| TYR | I:122 | I:175 | 4.0 | 0.017 | G | -58.6 | -39.8 | NA | NA | NA | |||||||||||||
| TYR | L:122 | L:175 | 3.0 | 0.013 | G | -58.2 | -40.6 | NA | NA | NA | |||||||||||||
| 5n4w | 2 | P40337 | 100.0 | 6e-117 |
X-RAY |
2017-06-07 | TYR | B:122 | V:175 | 34.0 | 0.148 | S | -93.3 | 0.6 | 34.0 | 0.148 | 0.0 | ||||||
| 6gfx | 3 | P40337 | 100.0 | 6e-117 |
X-RAY |
2018-07-11 | TYR | C:122 | C:175 | 14.0 | 0.061 | G | -52.2 | -45.3 | 14.0 | 0.061 | 0.0 |
HOH |
2.683 |
OH |
O |
||
| 6i7q | 4 | P40337 | 100.0 | 6e-117 |
X-RAY |
2019-11-27 | TYR | D:122 | V:175 | 4.0 | 0.017 | G | -49.5 | -44.6 | 4.0 | 0.017 | 0.0 |
HOH |
2.546 |
OH |
O |
||
| 6i7r | 4 | P40337 | 100.0 | 6e-117 |
X-RAY |
2019-11-27 | TYR | D:122 | V:175 | 4.0 | 0.017 | G | -52.7 | -42.3 | 4.0 | 0.017 | 0.0 |
HOH |
2.566 |
OH |
O |
||
| 6r7f | 9 | P40337 | 100.0 | 6e-117 |
EM |
2019-08-28 | TYR | I:122 | V:175 | 5.0 | 0.022 | T | -65.8 | -42.7 | 5.0 | 0.022 | 0.0 | ||||||
| 7khh | 3 | P40337 | 100.0 | 6e-116 |
X-RAY |
2021-02-24 | TYR | C:137 | C:175 | 3.0 | 0.013 | G | -57.0 | -44.1 | 3.0 | 0.013 | 0.0 |
HOH |
2.643 |
OH |
O |
||
| 7cjb | 1 | P40337 | 100.0 | 8e-116 |
X-RAY |
2021-07-14 | TYR | A:125 | A:175 | 4.0 | 0.017 | G | -47.8 | -38.8 | 4.0 | 0.017 | 0.0 | ||||||
| TYR | E:125 | E:175 | 4.0 | 0.017 | G | -48.2 | -39.8 | NA | NA | NA | |||||||||||||
| TYR | I:125 | I:175 | 4.0 | 0.017 | G | -47.0 | -40.2 | NA | NA | NA | |||||||||||||
| TYR | M:125 | M:175 | 5.0 | 0.022 | G | -47.2 | -40.7 | NA | NA | NA | |||||||||||||
| 6zhc | 1 | P40337 | 100.0 | 4e-113 |
X-RAY |
2020-08-05 | TYR | A:117 | AAA:175 | 5.0 | 0.022 | G | -51.9 | -43.4 | 5.0 | 0.022 | 0.0 |
EDO EDO HOH |
5.476 6.396 2.400 |
OH O OH |
O2 C2 O |
||
| 7pi4 | 1 | P40337 | 100.0 | 4e-113 |
X-RAY |
2021-09-29 | TYR | A:117 | AAA:175 | 2.0 | 0.009 | G | -53.6 | -36.8 | 2.0 | 0.009 | 0.0 |
EDO HOH |
6.635 2.552 |
OH OH |
O2 O |
||
| 6fmi | 3 | P40337 | 99.34 | 1e-109 |
X-RAY |
2018-04-11 | TYR | C:124 | C:175 | 4.0 | 0.017 | G | -53.1 | -40.4 | 4.0 | 0.017 | 0.0 |
HOH |
7.604 |
O |
O |
||
| TYR | F:124 | F:175 | 3.0 | 0.013 | S | -62.5 | -37.7 | NA | NA | NA | |||||||||||||
| 6fmj | 3 | P40337 | 99.34 | 1e-109 |
X-RAY |
2018-04-11 | TYR | C:124 | C:175 | 15.0 | 0.065 | T | -60.8 | -36.4 | 15.0 | 0.065 | 0.0 |
HOH |
2.651 |
OH |
O |
||
| TYR | F:124 | F:175 | 13.0 | 0.057 | G | -55.1 | -46.6 | NA | NA | NA | |||||||||||||
| TYR | I:124 | I:175 | 5.0 | 0.022 | G | -64.0 | -39.7 | NA | NA | NA | |||||||||||||
| TYR | L:124 | L:175 | 3.0 | 0.013 | G | -59.3 | -37.7 | NA | NA | NA | |||||||||||||
| 6fmk | 3 | P40337 | 99.34 | 1e-109 |
X-RAY |
2018-04-11 | TYR | C:124 | C:175 | 17.0 | 0.074 | G | -56.1 | -44.9 | 17.0 | 0.074 | 0.0 |
HOH |
2.707 |
OH |
O |
||
| TYR | F:124 | F:175 | 15.0 | 0.065 | G | -55.0 | -42.8 | NA | NA | NA | |||||||||||||
| TYR | I:124 | I:175 | 8.0 | 0.035 | S | -64.2 | -35.6 | NA | NA | NA | |||||||||||||
| TYR | L:124 | L:175 | 4.0 | 0.017 | G | -59.2 | -38.2 | NA | NA | NA | |||||||||||||
| 6hr2 | 2 | P40337 | 100.0 | 3e-108 |
X-RAY |
2019-06-12 | TYR | B:115 | B:175 | 4.0 | 0.017 | S | -71.5 | -43.7 | 4.0 | 0.017 | 0.0 |
HOH |
2.603 |
HH |
O |
||
| TYR | F:115 | F:175 | 5.0 | 0.022 | S | -71.6 | -43.8 | NA | NA | NA | |||||||||||||
| 6r6h | 12 | P40337 | 100.0 | 3e-107 |
EM |
2019-08-28 | TYR | L:116 | V:175 | 9.0 | 0.039 | H | -55.2 | -46.3 | 9.0 | 0.039 | 0.0 | ||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p40337-f1 | 1 | P40337 | 100.0 | 2e-156 | TYR | A:175 | A:175 | 5.0 | 0.022 | G | -55.1 | -44.7 | |