Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr5 132015565 . T A CCDS4158.1:NM_000589.3:c.343Tgg>Agg_NP_000580.1:p.115W>R Homo sapiens interleukin 4 (IL4), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4ydy 2 P05112 100.0 1e-92 X-RAY
 2015-03-04 TRP B:92 I:91 121.0 0.475 H -53.1 -39.1 2.0 0.008 0.467 A:None:0.467
 HOH
 2.893
 O
 O
TRP D:92 J:91 125.0 0.49 H -57.5 -37.0 NA NA NA
1hik 1 P05112 100.0 2e-92 X-RAY
 1996-01-29 TRP A:91 A:91 53.0 0.208 H -71.5 -52.0 53.0 0.208 0.0
1iar 1 P05112 100.0 2e-92 X-RAY
 2000-03-03 TRP A:91 A:91 71.0 0.278 H -62.7 -42.2 35.0 0.137 0.141 B:P24394:0.141
 HOH
 2.584
 O
 O
1rcb 1 P05112 100.0 2e-92 X-RAY
 1993-10-31 TRP A:91 A:91 57.0 0.224 H -67.7 -18.3 57.0 0.224 0.0 HOH
 3.690
 CZ2
 O
2b8u 1 P05112 100.0 2e-92 X-RAY
 2006-05-30 TRP A:91 A:91 58.0 0.227 H -62.4 -35.9 58.0 0.227 0.0 SO4
HOH
 6.954
3.652
 NE1
CZ2
 O3
O
2int 1 P05112 100.0 2e-92 X-RAY
 1994-01-31 TRP A:91 A:91 53.0 0.208 H -59.7 -39.6 53.0 0.208 0.0
3bpl 1 P05112 100.0 2e-92 X-RAY
 2008-02-05 TRP A:91 A:91 77.0 0.302 H -65.4 -44.0 41.0 0.161 0.141 B:P24394:0.141
 HOH
 4.256
 CD1
 O
3bpn 1 P05112 100.0 2e-92 X-RAY
 2008-02-05 TRP A:91 A:91 70.0 0.275 H -50.3 -55.9 49.0 0.192 0.083 B:P24394:0.082
1hij 1 P05112 99.22 1e-91 X-RAY
 1996-01-29 TRP A:91 A:91 45.0 0.176 H -61.3 -38.2 45.0 0.176 0.0
1hzi 1 P05112 99.22 1e-91 X-RAY
 2001-08-29 TRP A:91 A:91 52.0 0.204 H -61.7 -36.9 52.0 0.204 0.0 HOH
 2.908
 O
 O
2d48 1 P05112 99.22 1e-91 X-RAY
 2006-05-30 TRP A:91 A:91 58.0 0.227 H -60.4 -36.8 58.0 0.227 0.0 HOH
 3.568
 CZ2
 O
1bbn 1 P05112 96.21 2e-91 NMR
 1993-10-31 TRP A:95 A:95 54.0 0.212 H -88.9 -22.0 54.0 0.212 0.0
2b8z 1 P05112 99.22 2e-91 X-RAY
 2006-05-30 TRP A:91 A:91 52.0 0.204 H -65.2 -38.3 52.0 0.204 0.0 SO4
HOH
 7.177
2.922
 NE1
NE1
 O3
O
2b8x 1 P05112 99.22 4e-91 X-RAY
 2006-05-30 TRP A:91 A:91 60.0 0.235 H -63.9 -34.5 60.0 0.235 0.0 SO4
HOH
 7.067
3.515
 NE1
CZ2
 O3
O
2b90 1 P05112 98.45 1e-90 X-RAY
 2006-05-30 TRP A:91 A:91 64.0 0.251 H -62.8 -40.6 64.0 0.251 0.0 SO4
HOH
 7.146
3.759
 NE1
CB
 O3
O
2b8y 1 P05112 98.45 2e-90 X-RAY
 2006-05-30 TRP A:91 A:91 57.0 0.224 H -63.1 -39.1 57.0 0.224 0.0 SO4
HOH
 7.200
3.684
 NE1
CZ2
 O3
O
2b91 1 P05112 98.45 3e-90 X-RAY
 2006-05-30 TRP A:91 A:91 53.0 0.208 H -64.0 -36.3 53.0 0.208 0.0 SO4
HOH
 7.101
2.709
 NE1
O
 O3
O
5fhx 1 P05112 100.0 6e-88 X-RAY
 2016-03-30 TRP A:86 A:91 41.0 0.161 H -58.8 -37.5 41.0 0.161 0.0 HOH
 5.823
 CZ2
 O
6oel 1 P05112 93.8 8e-87 X-RAY
 2019-08-07 TRP A:91 A:91 124.0 0.486 H -71.7 -48.3 54.0 0.212 0.274 B:P24394:0.275
 NAG
 8.289
 CH2
 O6
3qb7 1 D4HNR6 93.8 1e-86 X-RAY
 2012-04-25 TRP A:94 A:91 70.0 0.275 H -62.3 -42.4 70.0 0.275 0.0
TRP B:94 B:91 90.0 0.353 H -56.2 -36.8 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p05112-f1 1 P05112 100.0 9e-113 TRP A:115 A:115 65.0 0.255 H -61.6 -41.4